海口市0~6岁儿童母亲人乳头瘤病毒疫苗接种意愿及影响因素分析

目的 对海口市0~6岁儿童母亲人乳头瘤病毒HPV疫苗接种意愿及影响因素进行分析。 方法 采用横断面研究的方法,选取来海南省妇女儿童医学中心进行健康查体的0~6周岁儿童的母亲为调查对象,对其宫颈癌相关知识知晓情况及HPV接种意愿进行调查,多因素logistic回归分析影响HPV疫苗接种意愿的主要因素。 结果 962例被调查对象中,宫颈癌基本概念知晓率88.9%,宫颈癌主要致病HPV类型知晓率21.0%,HPV感染主要途径知晓率36.7%;HPV疫苗意愿接种率79.9%,不愿意接种的主要原因为疫苗价格过高(29.6%)、担心疫苗的不良反应(28.3%)、担心疫苗达不到保护效果(27.5%)等。多因素分析发现,母亲HPV疫苗接种意愿的影响因素有文化程度(OR=1.977,P=0.011)、职业(OR=1.714,P=0.044)、家庭月收入(OR=1.869,P=0.018)、是否知晓宫颈癌基本概念(OR=2.188,P=0.005)、是否知晓致病HPV类型(OR=2.235,P=0.005)及是否知晓HPV感染途径(OR=2.056,P=0.009)。 结论 文化程度较高、工作相对稳定、家庭月收入较高及宫颈癌相关知识知晓率高的人群更愿意接种HPV疫苗,而疫苗价格及疫苗的安全性、有效性对HPV疫苗接种意愿影响较大,应加强宫颈癌及HPV疫苗相关知识宣传、降低疫苗价格,促进疫苗普及接种。     

怀化市医疗机构工作人员新型冠状病毒疫苗接种意愿及影响因素

目的 了解怀化市医疗机构工作人员新型冠状病毒疫苗(简称新冠疫苗)接种意愿及影响因素,为新冠疫苗的接种工作提供依据。 方法 采用多阶段分层抽样法选取怀化市市、县/区、乡镇三级23家医疗机构的工作人员,开展网络问卷调查;采用χ²检验、logistic回归分析其影响因素。 结果 3 392名(85.70%)调查对象愿意接种新冠疫苗;logistic回归分析显示,乡镇级、县级医疗机构调查对象、临床医生、护理人员的接种意愿更高[OR(95%CI):1.558(1.148~2.114)、1.386(1.112~1.726)、1.550(1.008~2.384)、1.747(1.165~2.618)];硕士及以上学历者接种意愿更低[OR(95%CI):0.446(0.243~0.816)];认为新冠肺炎危害严重、认可疫苗的安全性、有效性、在 2020年接种过流感疫苗者更愿意接种新冠疫苗[OR(95%CI):1.493(1.221~1.825)、2.134(1.669~2.728)、2.546(1.925~3.366)、2.185(1.287~3.709)]。 结论 怀化市医疗机构工作人员新冠疫苗的接种意愿总体较高,应加强新冠疫苗相关知识宣传,增强该人群对疫苗接种的信心,进一步提高新冠疫苗的实际接种率。     

郑州市孕妇接种流行性感冒疫苗的意愿及影响因素分析

目的 了解孕妇接种流行性感冒(简称流感) 疫苗的意愿及其影响因素,为推广孕妇接种流感疫苗提供依据。 方法 采用整群随机抽样方法,从2019年1月—2020年4月在郑州大学第一附属医院建档在册的孕妇中随机抽取2019年12月建档在册835例孕妇进行流感疫苗接种意愿问卷调查。采用单因素χ²检验和多因素logistic回归分析孕妇接种流感疫苗意愿的影响因素。 结果 调查的835例孕妇的年龄范围为20~45岁,平均(29.61±3.87)岁,愿意接种流感疫苗的孕妇占32.57%, 拒绝孕期接种流感疫苗的主要原因为担心对胎儿有不良影响(55.24%)及疫苗不良反应(43.52%)。对孕期接种意愿影响最大的因素为孕期接种流感疫苗知识知晓得分≥10 分(OR=2.323,95%CI:1.681~3.210),以及医生推荐接种(OR=2.151,95%CI:1.572~2.944)。此外年龄≥35 岁、孕期合并慢性疾病、家人接种流感疫苗、孕期感染流感病毒的危害知晓得分≥10分和知晓接种推荐政策也影响孕妇的疫苗接种意愿。 结论 郑州市孕妇对接种流感疫苗的意愿较低。建议加强流感疫苗接种相关知识的宣传,充分发挥医生的指导作用,积极推动孕妇的流感疫苗接种普及工作。     

台州市高校女大学生对HPV疫苗的认知及接种意愿影响因素调查分析

目的 探讨台州市高校女大学生对人乳头瘤病毒(human papilloma virus,HPV)疫苗的认知及接种意愿影响因素,为接种预防性HPV疫苗提供参考。方法 通过自制调查问卷,于2018年1月—2019年8月,对台州市高校11 236例女大学生调查HPV疫苗的认知及接种意愿,并经多因素logistic回归模型分析其影响因素。结果 11 236例女大学生中,了解宫颈癌10 726例(95.46%)、了解HPV病毒3 110例(27.68%)、了解预防性HPV疫苗1 753(15.60%);存在预防性HPV疫苗接种意愿8 473例(75.41%),不愿意接种预防性HPV疫苗2 763例(24.59%);多因素logistic回归分析发现,了解宫颈癌(OR=3.196)、知晓HPV病毒感染和宫颈癌有关(OR=1.463)、知晓HPV感染的传播途径(OR=1.593)、知晓预防性HPV疫苗(OR=3.338)、知晓接种预防性HPV疫苗能预防宫颈癌(OR=5.177)、知晓预防性HPV疫苗接种后需接受常规妇科检查(OR=1.938)、知晓预防性HPV疫苗接种最佳时期(OR=2.109)、知晓HPV疫苗不会增加性传播疾病风险(OR=2.028)女大学生接种HPV疫苗意愿更高。结论 台州市高校女大学生对HPV疫苗的认知率较低,但存在较高的HPV疫苗接种意愿,为提高女大学生对HPV疫苗的认知,需要校园定期组织女大学生参加HPV疫苗相关知识的健康宣教活动。     

新疆疏附县儿童麻疹发病危险因素分析

目的 探讨新疆疏附县儿童麻疹发病相关影响因素,为制定麻疹防控策略提供依据。 方法 选取2016—2018年度新疆疏附县125名8月龄~14岁儿童麻疹确诊病例为病例组,按照1∶1配对原则选择对照组,制定问卷调查表,回顾性收集可能影响儿童麻疹发病的相关资料,采用条件logistic回归进行影响因素分析。 结果 多因素logistic回归分析结果显示,近一个月医院就诊史是儿童麻疹发病的危险因素(OR=4.876,95%CI:1.350~17.608),而居室通风(OR=0.103,95%CI:0.039~0.269)、家长麻疹认知合格(OR=0.187,95%CI:0.071~0.493)、儿童接种麻疹成分疫苗(OR=0.475,95%CI:0.290~0.778)则为儿童麻疹发病的保护因素。 结论 应加强疏附县医院院内感染管理力度,加大麻疹防控知识宣传教育力度,全面提高儿童麻疹疫苗接种率。     

宁夏贫困地区婴幼儿营养包服用情况及影响因素

目的 了解宁夏贫困地区婴幼儿营养包服用情况并对其影响因素进行分析。方法 2017-2018年期间,采用多阶段PPS抽样调查法和随机等距抽样相结合的方法,对宁夏7个贫困县(区)2 120名6~24月龄婴幼儿看护人进行问卷调查分析,内容包括婴幼儿出生基本情况、营养包服用、看护人喂养和营养知识情况等。结果 婴幼儿营养包有效服用率为80.3%,汉族营养包有效服用率高于回族,无不适反应高于有不适反应,随着婴幼儿月龄增加有效服用率升高,母亲、父亲学历越高有效服用率越高,不同民族、月龄、不适反应、母亲学历组间的差异有统计学意义(P＜0.05)。多因素非条件Logistic回归分析显示,汉族(OR=0.635,95%CI:0.487~0.827,P=0.001)、无不适反应(OR=0.286,95%CI:0.192~0.425,P<0.001)、月龄(OR=0.970,95%CI:0.951~0.990,P=0.003)为婴幼儿营养包食用依从性保护因素,母亲年龄是其危险因素(OR=1.023,95%CI:1.002~1.045,P=0.029)。结论 宁夏贫困地区婴幼儿营养包食用依从性有待进一步提高,需针对其影响因素采取相关干预措施。     

山东省滨州市儿童流感疫苗接种率的变化趋势及影响因素分析

目的 对2015-2017年山东省滨州市5岁以下儿童10个接种门诊流感疫苗接种率现状进行调查分析,为儿童流感疫苗接种提供数据资料。方法 采用自制的调查问卷对滨州市480名5岁以下儿童父母进行问卷调查,并进行回顾性分析,采用Logistic回归模型分析5岁以下儿童流感疫苗接种的影响因素。结果 滨州市10个接种门诊5岁以下儿童流感疫苗接种率由2015年的42.29%(203/480)下降到2017年的20.21%(97/480);其中3~5岁以下儿童流感疫苗接种率由2015年的26.87%(129/480)下降到2017年的13.13%(63/480),3岁以下婴儿流感疫苗接种率由2015年的15.42%(74/480)下降到2017年的7.08%(34/480)均具有明显的下降趋势(χ²=11.073,14.312,P<0.05)。对儿童父母的问卷调查结果显示:不同文化程度、家庭人均月收入、职业、户籍所在地、是否接种过流感疫苗和支付医疗费用方式是影响儿童流感疫苗接种的主要因素,经多因素分析结果发现,父母文化程度初中以上(高中/中专/高职OR=1.49,95%CI: 1.08～2.04;本科/大专OR=2.45,95%CI: 1.61～3.73;硕士及以上OR=3.90,95%CI: 1.70～8.87)、家庭月人均收入3 000元及以上(3 000～5 999元OR=1.35,95%CI:1.07～1.71;≥6 000元OR=2.37,95%CI: 1.25～4.51)、职业为机关企事业单位员工(OR=3.15,95%CI: 1.71～5.80)、对流感疫苗知识知晓(OR=2.24,95%CI: 1.56～3.21)是影响5岁以下儿童家长流感疫苗接种率的重要因素(P<0.001)。结论 文化程度、家庭月人均收入、是否接种过流感疫苗是影响婴幼儿流感疫苗接种率的重要影响因素,应多层次开展有关流感及其疫苗接种知识的宣教。     

广州市荔湾区居民新冠疫苗接种意愿及影响因素

目的 了解广州市荔湾区常住居民对新冠疫苗的认识,探讨接种意愿及其影响因素,为提高新冠疫苗接种率提供依据。方法 通过问卷星,于2020年11月1日至12月15日邀请广州市荔湾区18~59岁常住居民在线填写问卷调查,内容包括基本资料、对新冠疫苗的认知和接种意愿等情况,采用描述流行病学方法对结果进行分析,采用多因素Logistic回归分析疫苗接种意愿的影响因素。结果 共调查5 763名18~59岁常住居民,其中男女分别占23.58%、76.42%,新冠疫苗接种的愿意率为82.44％。多因素Logistic回归分析结果显示,职业为教师（OR=3.009）、家务（OR=2.691）、医疗卫生人员（OR=2.652）、餐饮食品业（OR=2.292）的居民以及认为疫苗安全（OR=24.007）、认为得新冠肺炎的几率很大（OR=17.528）的居民接种意愿较高。结论 广州市荔湾区18~59岁常住居民接种新冠疫苗意愿较高,职业、对疫苗安全性的认知、对新冠肺炎的认知是居民新冠疫苗接种意愿的影响因素。     

新生儿重症监护病房医院感染现状及相关危险因素分析

目的 通过观察重症监护病房新生儿医院感染现状,筛查出高危因素,制定相应预防对策,控制新生儿感染。 方法 选取2018年1—12月在海南省妇幼保健院新生儿重症监护病房收治的患儿527例为研究对象,采用单因素χ²检验及多因素logistic回归分析其医院感染发生情况及相关影响因素。 结果 527例患儿中发生医院感染的新生儿24例,感染率4.55%。单因素分析结果显示发生医院感染和未发生医院感染的新生儿在体重(P=0.011)、胎龄(P＜0.001)、分娩方式(P=0.014)、有无机械通气(P=0.008)、有无静脉营养(P=0.001)、是否侵入式治疗(P＜0.001)等指标构成上差异有统计学意义。多因素logistic分析结果显示,影响重症监护病房新生儿发生医院感染的独立危险因素有新生儿体重偏低(OR=2.117,95%CI:1.988~2.254);早产(OR=2.077,95%CI:2.009~2.148);剖宫产(OR=1.276,95%CI:1.199~1.359);机械通气(OR=1.699,95%CI:1.621~1.78);静脉营养(OR=2.387,95%CI:2.342~2.433)和侵入式治疗(OR=1.522,95%CI:1.501~1.543)。 结论 重症监护病房新生儿医院感染率较高,应根据相应的危险因素制定预防对策,控制新生儿感染率。     

失眠症状与青少年学校表现的相关性研究

目的 分析我国青少年失眠症状与学校表现的相关性。方法 运用分层整群抽样法对上海市4 966名青少年进行失眠症状和学校表现的横断面调查。采用青少年睡眠障碍问卷(ASDQ)和学业成绩教师评估问卷(TSAF)分别对青少年失眠状况和学校表现进行评估。结果 调查对象平均年龄为(15.59±2.04)岁,男性占49.3%。多因素分析结果显示,失眠症状与青少年学校表现相关,具体因素有入睡困难与注意力不集中(OR=1.30,95%CI:1.11~1.52,P=0.001)、学业成绩差(OR=1.24,95%CI:1.06~1.45,P=0.007)及人际交往受挫(OR=1.26,95%CI:1.08~1.48,P=0.003);睡眠维持障碍与注意力不集中(OR=1.25,95%CI:1.06~1.46,P=0.007)和学习自觉性差(OR=1.22,95%CI:1.04~1.44,P= 0.017)相关;再次入睡困难与学习自觉性差(OR=1.20,95%CI:1.00~1.45,P=0.048)相关。结论 青少年失眠症状与学校不良表现具有相关性,应当引起足够重视,及时进行筛查和干预,以促进青少年睡眠健康和学校表现。     

浙江省≥60岁人群新冠疫苗接种意愿和影响因素

  目的  了解浙江省≥60岁人群新型冠状病毒疫苗(简称新冠疫苗)的接种意愿及其影响因素。  方法  2020年9月1日—2020年11月30日采用分层抽样法对浙江省≥60岁人群进行问卷调查,收集基本信息、接种意愿、COVID-19风险意识等信息,采用χ2检验比较各组接种意愿率的差异,并用多因素Logistic回归分析模型分析接种意愿的影响因素。  结果  共1 858名≥60岁老年人完成调查,其新冠疫苗免费接种、自费接种的意愿率分别为88.3%和66.1%。多因素Logistic回归分析模型显示,对于免费接种,居住在乡村(OR=1.6,95% CI:1.2~2.2)、无外出(OR=1.6,95% CI:1.1~2.3)、听说过COVID-19(OR=3.7,95% CI:2.4~5.8)、认为COVID-19会造成严重后果(OR=2.3,95% CI:1.6~3.5)的老年人接种意愿更高。愿意自费接种的主要原因是认同新冠疫苗的安全性和有效性;不愿意自费接种的原因主要包括新冠疫苗需要收费和担心新冠疫苗的不良反应。  结论  浙江省≥60岁人群新冠疫苗免费接种意愿较高,但仍应加强关于新冠疫苗知识的宣传教育,并落实全民免费接种政策,以增强该人群接种疫苗的依从性。     

广州市居民对新型冠状病毒疫苗的认知与接种意愿调查

目的 调查广州市居民对新冠疫苗的认知、接种意愿及影响因素，为新冠疫苗在居民中的推广提供理论依据和建议。方法 采用简单随机抽样方法对广州市居民进行电话调查，对数据进行χ2检验和多因素logistic回归分析。结果 回收有效问卷1 000份，居民新冠疫苗知晓率为83.60%（836/1 000），79.16%（547/691）愿意接种新冠疫苗；年龄≥40岁（OR = 0.524，95% CI: 0.291～0.943，P = 0.031）、未曾自费接种（OR = 1.456，95% CI: 1.030～2.059，P = 0.033）是影响居民疫苗知晓率的因素；女性（OR = 0.657，95% CI: 0.422～0.978，P = 0.038）、未曾自费接种（OR = 1.850，95% CI: 1.249～2.740，P = 0.002）是影响居民接种意愿的因素，疫苗无副作用（OR = 0.504，95% CI: 0.298～0.853，P = 0.011）和不清楚疫苗有效期（OR = 10.074，95% CI: 4.105～24.724，P = 0.031）是居民不接种新冠疫苗的重要影响因素。结论 广州市居民对新冠疫苗知晓度高、接种意愿强，但疫苗上市后立即接种的积极性低、认知尚匮乏，建议加强新冠疫苗相关知识的宣传教育。     

上海市大学生新型冠状病毒疫苗接种意愿及影响因素

目的 了解上海市大学生接种新型冠状病毒疫苗(新冠疫苗)的意愿及影响因素.方法 选择2021年2月23日-2021年3月15日上海市四所不同学科类别院校的学生进行在线问卷调查,分析新冠疫苗接种意愿率,采用多因素Logistic回归分析模型探讨影响新冠疫苗接种意愿的因素.结果 4462名被调查者接种意愿率为78.04％,L...     

Willingness to Receive COVID-19 Vaccination Among People Living With HIV and AIDS in China: Nationwide Cross-sectional Online Survey

BackgroundHIV infection is a significant independent risk factor for both severe COVID-19 presentation at hospital admission and in-hospital mortality. Available information has suggested that people living with HIV and AIDS (PLWHA) could benefit from COVID-19 vaccination. However, there is a dearth of evidence on willingness to receive COVID-19 vaccination among PLWHA.ObjectiveThe aim of this study was to investigate willingness to receive COVID-19 vaccination among a national sample of PLWHA in China.MethodsThis cross-sectional online survey investigated factors associated with willingness to receive COVID-19 vaccination among PLWHA aged 18 to 65 years living in eight conveniently selected Chinese metropolitan cities between January and February 2021. Eight community-based organizations (CBOs) providing services to PLWHA facilitated the recruitment. Eligible PLWHA completed an online survey developed using a widely used encrypted web-based survey platform in China. We fitted a single logistic regression model to obtain adjusted odds ratios (aORs), which involved one of the independent variables of interest and all significant background variables. Path analysis was also used in the data analysis.ResultsOut of 10,845 PLWHA approached by the CBOs, 2740 completed the survey, and 170 had received at least one dose of the COVID-19 vaccine. This analysis was performed among 2570 participants who had never received COVID-19 vaccination. Over half of the participants reported willingness to receive COVID-19 vaccination (1470/2570, 57.2%). Perceptions related to COVID-19 vaccination were significantly associated with willingness to receive COVID-19 vaccination, including positive attitudes (aOR 1.11, 95% CI 1.09-1.12; P<.001), negative attitudes (aOR 0.96, 95% CI 0.94-0.97; P<.001), perceived support from significant others (perceived subjective norm; aOR 1.53, 95% CI 1.46-1.61; P<.001), and perceived behavioral control (aOR 1.13, 95% CI 1.11-1.14; P<.001). At the interpersonal level, receiving advice supportive of COVID-19 vaccination from doctors (aOR 1.99, 95% CI 1.65-2.40; P<.001), CBO staff (aOR 1.89, 95% CI 1.51-2.36; P<.001), friends and/or family members (aOR 3.22, 95% CI 1.93-5.35; P<.001), and PLWHA peers (aOR 2.38, 95% CI 1.85-3.08; P<.001) was associated with higher willingness to receive COVID-19 vaccination. The overall opinion supporting COVID-19 vaccination for PLWHA on the internet or social media was also positively associated with willingness to receive COVID-19 vaccination (aOR 1.59, 95% CI 1.31-1.94; P<.001). Path analysis indicated that interpersonal-level variables were indirectly associated with willingness to receive COVID-19 vaccination through perceptions (β=.43, 95% CI .37-.51; P<.001).ConclusionsAs compared to PLWHA in other countries and the general population in most parts of the world, PLWHA in China reported a relatively low willingness to receive COVID-19 vaccination. The internet and social media as well as interpersonal communications may be major sources of influence on PLWHA’s perceptions and willingness to receive COVID-19 vaccination.     

Trends,patterns and psychological influences on COVID-19 vaccination intention: Findings from a large prospective community cohort study in England and Wales (Virus Watch)

BackgroundVaccination intention is key to the success of any vaccination programme, alongside vaccine availability and access. Public intention to take a COVID-19 vaccine is high in England and Wales compared to other countries, but vaccination rate disparities between ethnic, social and age groups has led to concern.MethodsOnline survey of prospective household community cohort study participants across England and Wales (Virus Watch). Vaccination intention was measured by individual participant responses to ‘Would you accept a COVID-19 vaccine if offered?’, collected in December 2020 and February 2021. Responses to a 13-item questionnaire collected in January 2021 were analysed using factor analysis to investigate psychological influences on vaccination intention.ResultsSurvey response rate was 56% (20,785/36,998) in December 2020 and 53% (20,590/38,727) in February 2021, with 14,880 adults reporting across both time points. In December 2020, 1,469 (10%) participants responded ‘No’ or ‘Unsure’. Of these people, 1,266 (86%) changed their mind and responded ‘Yes’ or ‘Already had a COVID-19 vaccine’ by February 2021. Vaccination intention increased across all ethnic groups and levels of social deprivation. Age was most strongly associated with vaccination intention, with 16–24-year-olds more likely to respond “Unsure” or “No” versus “Yes” than 65–74-year-olds in December 2020 (OR: 4.63, 95 %CI: 3.42, 6.27 & OR 7.17 95 %CI: 4.26, 12.07 respectively) and February 2021 (OR: 27.92 95 %CI: 13.79, 56.51 & OR 17.16 95 %CI: 4.12, 71.55). The association between ethnicity and vaccination intention weakened, but did not disappear, over time. Both vaccine- and illness-related psychological factors were shown to influence vaccination intention.ConclusionsFour in five adults (86%) who were reluctant or intending to refuse a COVID-19 vaccine in December 2020 had changed their mind in February 2021 and planned to accept, or had already accepted, a vaccine.     

中国一般人群及医务工作者的新冠肺炎疫苗接种意愿及影响因素研究

目的了解中国一般人群和医务工作者在新冠肺炎疫苗上市前的接种意愿及其影响因素。方法2020年6月18—30日,在中国东、中、西部三个城市,随机选择当地居民和医务工作者,通过电话调查和网络问卷的方式研究新冠肺炎疫苗接种意愿,并采用多因素logistic回归分析其影响因素。结果共有1874名一般人群和627名医务工作者参加本研究。一般人群和医务工作者的新冠肺炎疫苗接种意愿分别为82.9%和95.9%,监护者和看护人对小孩和老人的疫苗接种意愿分别为83.0%和77.8%。疫苗的有效性和接种意愿呈正相关。多因素logistic回归结果显示,相较于兰州,居住在上海(OR=0.314,95%CI:0.209~0.464)或武汉(OR=0.547,95%CI:0.354~0.836)的一般人群新冠肺炎疫苗接种意愿更低,而有流感疫苗接种史(OR=2.784,95%CI:1.254~6.279)的医务工作者更愿意接种新冠肺炎疫苗;对于新冠肺炎的风险认知更高的一般人群及医务工作者新冠肺炎疫苗接种意愿更高(OR_(一般人群)=2.046,95%CI:1.685~2.495;OR_(医务工作者)=1.843,95%CI:1.081~3.082)。不愿意接种的主要原因为担心疫苗的安全性和有效性。结论中国公众和医务工作者对新冠肺炎疫苗接种的需求和认知度较高,建议开展大规模疫苗接种时注重介绍疫苗安全性和有效性以提高新冠肺炎疫苗的接种率,促进尽早形成人群免疫屏障.     

上海市某区医务人员新冠疫苗接种情况及影响因素分析

目的 了解医务人员新冠疫苗的接种情况、影响因素及主观态度,为新冠疫苗的广泛接种提供理论依据.方法 选取上海市黄浦区全部的一级和二级医院共20所,采用随机抽样的方法抽取614名医务人员,利用自编问卷对其进行线上问卷调查.结果 共回收有效问卷609份,有效率99.2％.其中已接种新冠疫苗的有470人,未接种新冠疫苗的有13...     

Changes in COVID-19 vaccine acceptance rate among recovered critically Ill patients: A 12-month follow-up study

IntroductionWe surveyed a cohort of patients who recovered from severe SARS-CoV-2 infection to determine the COVID-19 vaccination rate. We also compared the willingness to accept COVID-19 vaccine before and after its availability to assess changes in perception and attitude towards vaccination.Materials and MethodsRecovered patients with severe hypoxemic respiratory failure from SARS-CoV-2 infection treated in the ICU at Grady Memorial Hospital, Atlanta, Georgia between April 1, 2020, and June 30, 2020 were followed up over a 1-year period to assess vaccine acceptability and acceptance rates, and changes in perception towards COVID-19 vaccination before and after vaccine availability.ResultsA total of 98 and 93 patients completed the initial and follow up surveys respectively. During the initial survey, 41% of the patients intended to receive vaccination, 46% responded they would not accept a vaccine against COVID-19 even if it were proven to be ‘safe and effective ‘and 13% undecided. During the follow up survey, 44% of the study cohort had received at least one dose of a COVID-19 vaccine. Major reasons provided by respondents for not accepting COVID-19 vaccine were lack of trust in the effectiveness of the vaccine, pharmaceutical companies, government, vaccine technology, fear of side effects and perceived immunity against COVID-19. Respondents were more likely to be vaccinated if recommended by their physicians (OR 6.4, 95% CI 2.8–8.3), employers (OR 2.5, 95% CI 1.9–5.8), and family and friends (OR 1.6, 95% CI 1.1–4.5).ConclusionWe found a suboptimal COVID-19 vaccination rate in a cohort of patients who recovered from severe infection. COVID-19 vaccine information and recommendation by healthcare providers, employers, and family and friends may improve vaccination uptake.     

Trust in government,intention to vaccinate and COVID-19 vaccine hesitancy: A comparative survey of five large cities in the United States,United Kingdom,and Australia

BackgroundThere is widespread hesitancy towards COVID-19 vaccines in the United States, United Kingdom, and Australia.ObjectiveTo identify predictors of willingness to vaccinate against COVID-19 in five cities with varying COVID-19 incidence in the US, UK, and Australia.DesignOnline, cross-sectional survey of adults from Dynata’s research panel in July-September 2020.Participants, settingAdults aged 18 and over in Sydney, Melbourne, London, New York City, or Phoenix.Main outcomes and measuresWillingness to receive a COVID-19 vaccine; reason for vaccine intention.Statistical methodsTo identify predictors of intention to receive a COVID-19 vaccine, we used Poisson regression with robust error estimation to produce prevalence ratios.ResultsThe proportion willing to receive a COVID-19 vaccine was 70% in London, 71% NYC, 72% in Sydney, 76% in Phoenix, and 78% in Melbourne. Age was the only sociodemographic characteristic that predicted willingness to receive a COVID-19 vaccine in all five cities. In Sydney and Melbourne, participants with high confidence in their current government had greater willingness to receive the vaccine (PR = 1.24; 95% CI = 1.07–1.44 and PR = 1.38; 95% CI = 1.74–1.62), while participants with high confidence in their current government in NYC and Phoenix were less likely to be willing to receive the vaccine (PR = 0.78; 95% CI = 0.72–0.85 and PR = 0.85; 95% CI = 0.76–0.96).LimitationsConsumer panels can be subject to bias and may not be representative of the general population.ConclusionsSuccess for COVID-19 vaccination programs requires high levels of vaccine acceptance. Our data suggests more than 25% of adults may not be willing to receive a COVID-19 vaccine, but many of them were not explicitly anti-vaccination and thus may become more willing to vaccinate over time. Among the three countries surveyed, there appears to be cultural differences, political influences, and differing experiences with COVID-19 that may affect willingness to receive a COVID-19 vaccine.