腹腔镜手术治疗输卵管妊娠158例临床分析

目的探讨腹腔镜在输卵管妊娠治疗中的价值。方法158例输卵管妊娠患者采用腹腔镜下保守性手术或根治性手术。结果腹腔镜下行保守性手术占80.3%,根治性手术占18.4%。保守性手术组无一例发生持续性异位妊娠,发生率为0%,术后妊娠率为60.8%。腹腔镜输卵管妊娠保守性手术治疗保留了输卵管的功能,增加了病人生育机会。结论腹腔镜手术治疗可作为输卵管妊娠的首选方法。     

保留生育功能的腹腔镜下输卵管妊娠手术52例

目的探讨保留生育功能的腹腔镜手术治疗输卵管异位妊娠的临床价值。方法回顾分析要求保留生育功能的输卵管异位妊娠病例52例,所有患者在气管插管全麻下行腹腔镜手术治疗。结果52例异位妊娠患者腹腔镜手术均取得成功,所有患者术中均保留了输卵管。随访5～9个月,无并发症发生。结论保留生育功能的腹腔镜手术治疗输卵管妊娠微创、安全、有效,术后恢复快。但它需要一定的腹腔镜手术训练。     

电视腹腔镜手术治疗异位妊娠155例临床分析

目的探讨腹腔镜手术治疗异位妊娠的方法及手术病例选择.方法对155例腹腔镜手术治疗异位妊娠的临床资料进行回顾分析.结果 155例均成功行腹腔镜手术,无中转,有生育要求的73例均保留了输卵管.结论腹腔镜下治疗异位妊娠手术对患者损伤小,恢复快,但应注意病例选择并尽量避免再次异位妊娠的发生.     

腹腔镜术中应用甲氨蝶呤预防持续性异位妊娠临床分析

临床上异位妊娠的发病率呈逐年上升,发病年龄趋于年轻化的趋势,其中输卵管妊娠占了95％以上,对于患输卵管妊娠有保留生育要求的患者,保留输卵管的治疗效果尤显重要[1].单纯实施腹腔镜下保留输卵管的手术,有可能发生持续性异位妊娠(PEP)的不足.     

腹腔镜保守性手术治疗输卵管妊娠70例分析

目的 探讨腹腔镜下未破裂型输卵管妊娠或早期破裂输卵管妊娠保守手术的临床应用.方法 选择70例要求保留生育功能者进行保守治疗,即采取腹腔镜下输卵管开窗术及挤压法排除输卵管妊娠物及甲氨蝶呤患侧输卵管局部系膜下注射,配合口服米非司酮治疗.结果 70例全部成功,且均保留了输卵管.对1年内有生育要求的50例患者进行随访,有28例受孕,27例为宫内妊娠,1例再次输卵管妊娠.结论 输卵管妊娠腹腔镜下保守手术配合药物治疗可作为希望保留生育功能的异位妊娠患者的首选方案.     

输卵管妊娠腹腔镜保守治疗62例临床分析

目的 探讨腹腔镜保留输卵管手术治疗输卵管妊娠的效果.方法 回顾性分析笔者所在医院2007～2009年收治的62例有生育要求的输卵管妊娠妇女,采用腹腔镜保守治疗输卵管妊娠的临床资料.结果 62例输卵管妊娠患者均于腹腔镜下顺利完成手术,无1例中转开腹,手术时间短,术中出血少,术后无1例持续性异位妊娠发生.结论 腹腔镜保守治疗输卵管妊娠是安全可行的.     

腹腔镜手术在异位妊娠治疗中的应用

目的 探讨腹腔镜手术在异位妊娠治疗中的应用.方法 回顾性分析腹腔镜手术治疗异位妊娠60例和随机抽取开腹手术治疗异位妊娠60例的临床资料.结果 腹腔镜手术治疗异位妊娠60例均获成功,无一例中转开腹.比较输卵管开窗术、输卵管切除术,经统计学检验,差异有非常显著性(P<0.01).结论 腹腔镜手术是异位妊娠治疗的首要选择,以输卵管开窗术为主,达到了保留输卵管和生育功能的目的,异位妊娠破裂致腹腔内大出血不再是腹腔镜手术的禁忌症.     

腹腔镜下输卵管妊娠保留生育功能手术65例分析

异位妊娠是妇科常见急腹症之一，近年来国内外报道异位妊娠发生呈上升趋势，而输卵管妊娠占异位妊娠90％以上。随着腹腔镜手术在妇科领域的广泛应用，腹腔镜手术治疗异位妊娠有取代开腹手术的趋势。现就我院2004年2月～2006年6月65例有生育要求的输卵管妊娠，采用腹腔镜保留输卵管手术的临床资料分析如下。     

腹腔镜诊治异位妊娠32例临床分析

目的探讨腹腔镜对异位妊娠诊治的价值。方法采用腹腔镜下诊治32例异位妊娠患者,均在入院24h内接受急诊LSC手术。结果32例异位妊娠手术全部在腹腔镜下完成,无中转开腹,无并发症发生。结论腹腔镜诊治异位妊娠应为首选。手术方法根据患者生育情况及输卵管破坏程度决定输卵管是否保留。     

甲氨蝶呤配合腹腔镜保守手术治疗输卵管妊娠的临床分析

目的 探讨术前辅助甲氨蝶呤配合腹腔镜保守手术治疗输卵管妊娠的疗效及临床价值.方法 分析76例有生育要求、行腹腔镜保守手术治疗的输卵管妊娠患者的临床资料,其中术前应用甲氨蝶呤配合保留输卵管的腹腔镜手术治疗40例(研究组),行腹腔镜保留输卵管手术并术中局部注射甲氨蝶呤治疗36例(对照组),比较2组患者手术时间、术中出血、术后血血清人绒毛膜促性腺激素(HCG)下降、持续性异位妊娠发生率及术后输卵管通液的情况.结果 所有患者均成功实施保留患侧输卵管的腹腔镜手术,无中转开腹病例;研究组手术时间短、术中出血少、术后输卵管通畅率高,与对照组比较差异有统计学意义(P＜0.05),术后血HCG降至正常天数2组差异无统计学意义(P＞0.05).2组均未有持续性异位妊娠发生.结论 甲氨蝶呤配合保守性腹腔镜手术治疗输卵管妊娠不仅能减少术中出血,有效预防持续性异位妊娠的发生,确保手术的成功率及安全性,还能提高术后输卵管复通的几率,对改善患者术后的生育功能具有积极的临床意义.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.