儿童上呼吸道咳嗽综合征低温等离子腺样体消融治疗31例分析

目的:探讨鼻内镜低温等离子腺样体消融治疗儿童上呼吸道咳嗽综合征的疗效及安全性.方法:2007年10月～2010年3月对159例慢性咳嗽患儿行鼻内镜检查,将腺样体肥大合并咽后壁有脓性分泌物的31例(即上呼吸道咳嗽综合征伴腺样体肥大)患儿手术治疗,分析鼻内镜下行低温等离子腺样体消融术后对缓解患儿咳嗽的疗效.结果:术后随访6～12个月,痊愈25例,好转5例,无效1例,总有效率(包括痊愈和好转例数)为96.7％.结论:鼻内镜下行低温等离子腺样体消融术对上吸道咳嗽综合征伴腺样体肥大疗效确切.     

抽动障碍患儿的药物治疗与心理治疗临床分析

目的:探讨治疗抽动障碍(TD)的药物疗法与心理疗法及效果.方法:以1999年6月～2000年12月就诊并接受治疗的58例抽动障碍患儿为对象,分别对不同类TD患者(TTD、CTD、TS三类)施以不同的治疗方法,对TTD采用四步心理治疗法,对CTD、TS患者给予小剂量每日1次的氟哌啶醇(视病情变量)药物治疗配合心理调适.结果:小剂量每日1次服用氟哌啶醇同时配合心理治疗对CTD、TS有效.四步法心理治疗方案对TTD患儿有效,伴发声性抽动患儿进行心理调适,同时有必要选择性用药.结论:四步心理疗法及新的用药方案有效.     

儿童咳嗽变异性哮喘的肺功能改变

咳嗽变异性哮喘 (cough variance asthma,CVA)是哮喘的一种特殊形式 ,在临床上表现为一部分哮喘患儿长期、反复咳嗽 ,体检时无哮鸣音 ,易被误诊为上呼吸道感染或支气管炎。为此我们对 2 4例 CVA患儿进行了肺功能测定和支气管舒张试验 ,现报告如下。1　材料和方法1.1　对象　 (1) CVA组 :长期、反复咳嗽 ,体检无哮鸣音并排除肺部感染等疾病患儿 2 4例 ,男 17例 ,女 7例 ,年龄 6至12岁 ,平均 (8.73± 2 .0 0 )岁 ,咳嗽时间为 3个月至 2年 ,平均(7.5 8± 4.37)个月。 (2 )哮喘组 :缓解期典型哮喘患儿 2 0例 ,男 13例 ,女 7例 ,年龄 6至 12…     

儿童慢性咳嗽80例病因分析

目的 探讨儿童慢性咳嗽的病因.方法 对笔者所在医院2006年4月至2007年4月诊治的慢性咳嗽患儿诊治资料进行分析.结果 在80例慢性咳嗽患儿中,咳嗽变异性哮喘42例,鼻后滴流综合征20例,感染后咳嗽12例,心理性咳嗽6例.结论 儿童慢性咳嗽病因较多,根据咳嗽症状、辅助检查、治疗效果等大部分能确定病因.     

院前患儿死亡分析

我院儿科自1997年来共接诊就诊时死亡患儿52例,现总结如下: 1 一般资料 52例中,新生儿11例,1个月至1岁19例,1岁至3岁10例,3岁至6岁7例,6岁至10岁4例,12岁1例.其中有新生儿窒息史者4例,新生儿出血症史者1例,有中毒性痢疾史者3例,有惊厥史者8例,气管异物1例,电击伤1例,溺水2例,农药中毒2例,8例死亡前有轻度发热、咳嗽或腹泻病史,22例死亡后其家长说不出有任何诱因.     

伴有咽喉炎样表现的慢性咳嗽的病因分布

目的调查伴有咽喉炎样表现的慢性咳嗽患者的病因分布。方法收集2002年12月至2010年3月广州呼吸疾病研究所门诊伴有咽喉炎样表现的慢性咳嗽患者。按慢性咳嗽病因诊断程序进行病因诊断,详细询问病史和查体,进行通气功能＋支气管激发试验、诱导痰细胞学检查、食管24小时pH值监测等检查,结合治疗反应确定病因诊断。结果共纳入伴有咽炎样表现的慢性咳嗽患者326例,男176例,女150例;平均年龄（41±13）岁,病程中位数为24个月（2～480个月）。最后明确诊断上气道咳嗽综合征或鼻后滴流综合征73例（23.31%）,咳嗽变异性哮喘61例（18.71%）,嗜酸细胞性支气管炎70例（22.47%）,胃食管反流性咳嗽54例（16.56%）,变应性咳嗽48例（14.72%）,其他病因28例（8.59%）,病因不明12例（3.68%）。伴发咽喉炎样表现的各个常见病因之间比例无显著差异。结论在伴有咽喉炎样表现的慢性咳嗽患者中,上气道咳嗽综合征的比例与其他病因的比例无显著性差异,表明单纯的咽喉炎样表现对上气道咳嗽综合征没有诊断价值。     

咳嗽变异性哮喘30例临床分析

我们将 2 0 0 0年 1月～ 2 0 0 2年 1月在我院就诊的咳嗽持续1个月以上的患儿 40例为研究对象 ,给予平喘药物和抗过敏药物试验性治疗。其中 30例治疗有效 ,现报告如下 :1　临床资料1 1　一般资料 :30例中男 18例 ,女 12例 ,年龄 1～ 3岁 6例 ,～ 5岁 10例 ,～ 7岁 8例 ,～ 10岁 6例。咳嗽呈持续性干咳7例 ,喉咙发痒者 3例 ,反复发作性咳嗽、以夜间或清晨发作、白天咳嗽轻或不咳者 2 0例。运动后咳嗽加重者 13例 ,有过荨麻疹病史的 10例 ,有药物过敏史者 7例。 1、2级亲属中有哮喘病的 8例。 30例患儿中咳嗽是唯一症状 ,无呼吸困难和喘息 ,血…     

佩利措伊斯-梅茨巴赫病临床及遗传学特征分析

目的 探讨佩利措伊斯-梅茨巴赫病(PMD)的临床及分子遗传学特征.方法 回归性分析2015年6月至2020年10月郑州大学第三附属医院确诊的12个家系共14例PMD患儿的临床表现和基因突变特点.结果 14例均为男性,就诊年龄5 d至10岁,起病年龄1 d至7个月.首发症状表现为眼球震颤9例,大运动发育迟缓3例,呻吟样呼...     

抽动障碍患儿的药物治疗与心理治疗临床分析

目的 :探讨治疗抽动障碍 (TD)的药物疗法与心理疗法及效果。方法 :以 1999年 6月～ 2 0 0 0年12月就诊并接受治疗的 5 8例抽动障碍患儿为对象 ,分别对不同类TD患者 (TTD、CTD、TS三类 )施以不同的治疗方法 ,对TTD采用四步心理治疗法 ,对CTD、TS患者给予小剂量每日 1次的氟哌啶醇 (视病情变量 )药物治疗配合心理调适。结果 :小剂量每日 1次服用氟哌啶醇同时配合心理治疗对CTD、TS有效。四步法心理治疗方案对TTD患儿有效 ,伴发声性抽动患儿进行心理调适 ,同时有必要选择性用药。结论 :四步心理疗法及新的用药方案有效。     

儿童咳嗽变异性哮喘136例临床分析

目的探讨儿童咳嗽变异性哮喘（CVA）的相关因素、诊断和治疗方法。方法选取哮喘专科门诊的136例CVA患儿,进行相关因素调查问卷资料统计,临床诊断和治疗结果等资料分析。结果 136例CVA患儿春秋两季多发,反复呼吸道感染、活动、冷空气刺激、过敏体质、家族过敏史及环境因素是相关因素,支气管激发试验阳性和支气管舒张剂诊断性治疗有效。抗哮喘治疗,随访观察3个月后,咳嗽症状消失或明显改善123例,有效率90.6%。结论对儿童长期咳嗽,并有相关诱因,抗感染治疗无效,抗哮喘治疗有效,并排除其他疾病的考虑CVA的诊断,以吸入糖皮质激素治疗为主。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.