真皮下血管网薄皮瓣在手部软组织缺损修复中的应用

目的　研究真皮下血管网薄皮瓣在手部软组织缺损修复中的应用。方法　对因外伤、热电等烧伤引起的手部软组织缺损或瘢痕挛缩畸形２３ 例（ 皮瓣面积为１６ ｃｍ ×５ ｃｍ ～８ ｃｍ ×４ ｃｍ） 患者,采用真皮下血管网皮瓣修复。结果　断蒂时间最短为术后７ ｄ ,最长为术后１２ ｄ ,２３ 例患者均获得满意效果。结论　该薄皮瓣在各种原因引起的手部软组织缺损修复中有其明显优点。     

腹部真皮下血管网薄皮瓣在手部软组织缺损修复中的应用

目的探讨腹部真皮下血管网薄皮瓣在手部软组织缺损修复中的应用。方法采用腹壁真皮下血管网薄皮瓣修复手部软组织缺损１２例，其中外伤引起的疤痕挛缩８例，热压伤致骨、肌腱外露４例。皮瓣面积３．５ｃｍ×７．５ｃｍ～９ｃｍ×１５ｃｍ。断蒂时间最短为７ｄ，最长为１２ｄ，平均为８．３ｄ。皮瓣蒂部创面用辐照猪皮覆盖。结果皮瓣全部一期成活，手外形及功能恢复较满意。应用辐照猪皮能减少蒂部伤口渗出和感染。结论腹壁真皮下血管网薄皮瓣特别适用于手部软组织缺损的修复。     

腓肠神经伴行血管为蒂的逆行岛状皮瓣修复足跟部皮肤缺损

探讨腓肠神经伴行血管为蒂的逆行岛状皮瓣临床应用的可能性。足跟部软组织缺损１１例中,慢性溃疡５例,跟骨骨髓炎２例,外伤后跟腱外露皮肤缺损４例。皮瓣面积４ｃｍ×３ｃｍ～８．０ｃｍ×９．５ｃｍ皮瓣移植后全部成活。腓肠神经伴行血管为蒂的逆行岛状皮瓣血供可靠,是足跟部软组织修复方法的理想选择。     

前臂背桡侧逆行筋膜蒂岛状皮瓣的临床应用

目的介绍一个新的皮瓣供区一一前臂背桡侧逆行筋膜蒂岛状皮的瓣的临床应用价值．方法以骨间后动脉桡侧支为轴型血管设计前臂背桡侧逆行的膜蒂岛状皮瓣修复手部软组织缺损８例，皮瓣面积６ｃｍ×３ｃｍ～１４ｃｍ×６ｃｍ．结果８个皮瓣全部成活，创口一期愈合．结论前臂背桡侧皮具有血供丰富，切取方便，损伤小，皮瓣质地佳，可制成感觉皮瓣等优点．逆行转位可修复腕、手部的皮肤缺损，其旋转弧可达近指关节．     

真皮下血管网薄皮瓣在手部软组织缺损修复中的应用

目的 研究真皮下血和网薄皮瓣在手部软组织缺损修复中的应用。方法 对因外伤、热电等烧伤引起的手部软组织缺损或瘢痕挛缩畸形２３例（皮瓣面积为１６ｃｍ×５ｃｍ－８ｃｍ×４ｃｍ）患,采用真皮下血管网皮瓣修复。结果 断蒂时间最短为术后７ｄ最长为术后１２ｄ,２３例患均获得满意效果。结论 该薄皮瓣在各种原因引起的手剖软组织缺损修复中有其明显优点。     

股薄肌皮瓣转移修复女性外阴恶性肿瘤根治术后的组织缺损

利用带血管蒂股薄肌皮瓣转移修复女性外阴恶性肿瘤根治术后的组织缺损３例，缺损面积最大１４ｃｍ×７ｃｍ，肌皮瓣面积最大１６ｃｍ×９ｃｍ。肌皮瓣全部一期成活。讨论了带血管蒂股薄肌皮瓣转移或移植时应注意的问题。     

皮瓣或肌皮瓣修复大块深度皮肤及软组织缺损

我科自１９９６年５月以来对８例不同原因所造成的皮肤及软组织大块深度缺损,采用各种皮瓣（或肌皮瓣）修复,获得了功能和形态满意的治疗效果。１　临床资料本组共８例,男６例,女２例,年龄５～６１岁。缺损范围５ｃｍ×５ｃｍ～１６ｃｍ×２２ｃｍ。其中肿瘤切除术后５例,电击伤１例,慢性溃疡１例,外伤１例;８例均同时伴有深部重要组织（如血管神经、肌腱、骨骼）裸露,另有面颊部洞穿性缺损１例。２　修复方法　　２例足跟部基底细胞癌扩大切除术后缺损,分别采用小腿内侧逆行岛状皮瓣及跖内侧皮瓣修复。１例足跟部慢性溃疡在外院…     

背阔肌游离移植皮瓣修复小腿远端及足大面积皮肤软组织缺损

目的:探讨应用背阔肌游离移植皮瓣修复足部大面积皮肤软组织缺损的可行性.方法:2000年3月～2008 年1 月, 收治四肢组织缺损22 例, 其中男性20例,女性2例;年龄22岁～45岁,中位年龄30岁.应用带血管、神经蒂的背阔肌游离皮瓣与胫后血管、神经吻合修复小腿远端及足部的皮肤软组织缺损22例,皮瓣面积最大为25cm×15cm,最小11cm×9cm.结果:20例背阔肌皮瓣游离移植术后血循环恢复良好,肌皮瓣顺利成活.2例延迟愈合,供区创面直接缝合67 例,部分缝合加植皮43 例.结论:背阔肌皮瓣的血管粗,切取范围大,耐磨损,可以修复小腿远端及足大面积皮肤软组织缺损.     

背阔肌皮瓣移植治疗小腿皮肤软组织缺损

目的观察背阔肌皮瓣移植治疗小腿大块组织缺损的疗效。方法通过吻合血管的方法进行背阔肌皮瓣移植治疗小腿大块软组织缺损共15例。结果全部病例移植的背阔肌皮瓣均存活,创面得以满意的修复。结论该术式在小腿皮肤软组织大量缺损又无法用局部带蒂肌皮瓣修复的情况下是一种疗效可靠的治疗办法。     

岛状斜方肌肌皮瓣在头颈外科中的应用

本文介绍自１９８５年４月至１９９３年７月应用岛状斜方肌肌皮瓣整复口腔颌面部恶性肿瘤术后组织缺损２３例的经验。其中６例选用颈横动、静脉血管蒂，５、例为上斜方肌蒂，８例同时采用包含枕动脉的上斜方肌蒂与颈横动、静脉血管蒂的双蒂瓣。４例吻合血管游离移植，均获成功。肌皮瓣面积最大１２ｃｍ×８ｃｍ，最小６ｃｍ×４ｃｍ。作者对肌皮瓣类型的选择、手术方法及其优缺点进行了讨论。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.