沈阳市2697名健康体检者超声跟骨骨密度调查分析

目的 了解沈阳地区健康男、女的骨密度情况。方法 回顾性分析2008~2010年中国医科大学附属盛京医院体检中心体检的1216名女性和1481名男性沈阳市健康体检者的骨密度，检测方法为定量超声跟骨骨密度测定。结果 女性平均T值-1.216±0. 960，男性平均T值-0.750±1. 028,二者差异显著；女性骨质疏松93例，占7.65%.，骨量减少663例，占52. 56%;男性骨质疏松37例，占 2.5%，骨量减少616例，占41.59%_。结论 女性各年龄段T值均低于男性，随着年龄增加，男女T值 均逐渐下降，进入围绝经期后女性T值下降更为迅速，定量超声跟骨骨密度测定可以作为骨量减少及骨质疏松的筛查手段。     

湖北孝感2950例健康人群桡骨超声骨密度 调查分析

目的调查湖北孝感部分企事业单位健康体检人群的骨密度变化规律及骨质疏松（OP)患病 情况，为OP的诊断和防治提供科学依据。方法应用定量超声骨密度仪对本地区四50例健康体检 人群进行骨定量超声检测和分析。结果女性桡骨超声速率（SOS)峰值出现在46~50岁，50岁以后 缓慢下降，60岁以后下降趋势明显。男性桡骨SOS峰值出现在51~ 55岁，之后呈缓慢下降。50岁以 上，OP患病率男性为14.0%，女性为41.6%，女性显著高于男性(P<0. 01)，并且，各年龄段女性OP 发生率明显高于男性（P<0.01 )。结论随着年龄的增加，男女性骨质疏松发生率均逐渐增加，定量 超声适用于普查，可用于骨质疏松的早期诊断，并进行早期预防。     

北京地区3859名体检人群骨密度调查及骨量异常患病率分析

目的调查北京地区健康体检人群骨密度的情况以及骨量减少和骨质疏松的患病率,为骨质疏松症的防治提供参考。方法选择2017年1月至2018年12月在中日友好医院健康体检中心进行健康体检的人群,排除继发性骨质疏松症及其他影响骨代谢的因素,共3859名。其中男性2067名,女性1792名。年龄20~83岁,平均年龄(51.29±11.18)岁,按性别及年龄每10年一组。采用美国GE公司的LUNAR Prodigy双能X线骨密度仪测量受试者腰椎1~4正位及股骨颈和全髋的骨密度。分析各组不同部位骨密度情况及骨量异常(包括骨量减少和骨质疏松)的患病率。采用SPSS 22.0统计软件进行分析,以P<0.05为差异有统计学意义。结果①男性腰椎1~4骨密度峰值在20~29岁,股骨颈和全髋骨密度峰值在30~39岁。女性各部位骨密度峰值均在30~39岁。②随年龄增长,男性和女性骨量异常患病率均呈上升趋势,50岁以上女性骨量异常患病率显著上升,明显高于同年龄组男性。③30~59岁男性和女性腰椎骨量异常患病率均明显高于髋部;70岁以上男性和60岁以上女性髋部骨量异常患病率明显高于腰椎。结论中老年人群尤其是绝经后女性是骨质疏松症的高危人群;老年人群的骨质疏松筛查可以考虑选择髋部骨密度为主。     

大庆地区1096例汉族人群骨密度调查及骨质疏松发生率分析

目的 调查大庆市1096例健康汉族人群骨密度,了解该地区健康人群骨量峰值、骨密度变化的规律及骨质疏松发生率。方法 采用美国GE公司生产的Luner Prodigy Advance型骨密度仪,检测受试者腰椎和股骨颈骨密度（BMD）。将1096例检测结果按不同性别每5岁为1年龄组,应用SPSS19.0软件统计分析骨密度测量指标及骨质疏松（OP）发生率。结果 大庆市汉族男、女性人群腰椎骨密度峰值分别为1.197±0.203、1.192±0.145,股骨颈骨密度峰值分别为0.977±0.157、0.918±0.128。其峰值骨量年龄男性为45～49岁,50岁以后开始缓慢下降。其峰值骨量年龄女性为40～49岁,50岁以后开始缓慢下降。50～54岁年龄段男性骨质疏松症发生率为5.56%,女性为5.67%;55～59岁年龄段男性骨质疏松症发生率为7.32%,女性为11.51%;60～64岁年龄段男性骨质疏松症发生率为15.15%,女性为28.28%;65～69岁年龄段男性骨质疏松发生率为26.67%,女性为29.41%;70～74岁年龄段男性骨质疏松发生率为25.00%,女性为44.44%;75～79岁年龄段男性骨质疏松发生率为36.36%,女性为77.78%;80岁以上男性骨质疏松发生率为66.67%,女性为83.33%。结论 大庆市汉族人群不同年龄及同年龄组两性之间比较骨密度测定值差异显著（P<0.01）。55岁以后各年龄段女性骨质疏松发生率明显高于男性（P<0.01）。本研究报告的骨密度峰值大于沈阳地区,与合肥地区相近,略低于贵阳地区。OP发生率与合肥地区比较相近,略低于沈阳地区。     

双能X线骨密度测量和超声骨密度检测在社区居民骨质疏松症筛查中的应用研究

目的回顾性研究重庆城区居民的骨密度情况,了解该区域人群骨量减少和骨质疏松的患病率,分析比较双能X线与定量超声桡骨骨密度检查方法的优劣,为骨质疏松的早防早治提供科学依据。方法采集2012年9月至2016年12月在西南大学医院健康管理中心完成桡骨远端骨密度检测且资料完备的9158名(男性4577名,女性4581名)健康汉族成年体检者数据,随机采用双能X线测量法或定量超声检测法进行检测,根据T值判定骨质疏松并计算其检出率。结果该人群骨质疏松总检出率为15.6%,其中男性为9.5%,女性为21.6%。随着年龄的增加,男女性骨质疏松的检出率不断上升,骨量正常人群比例呈不断下降趋势。40岁以上人群骨质疏松总检出率为19.0%,男性和女性分别为11.1%和27.3%;50岁以上人群骨质疏松总检出率为23.3%,男性和女性分别为13.3%和33.7%。两种骨密度检测方法比较,桡骨定量超声法骨质疏松的检出率高于双能X线测量法(P0.001)。结论重庆城区居民的骨质疏松检出率高于全国水平,属于骨质疏松高发地区,该区域人群骨健康状况堪忧;因地制宜选择便捷高效经济的骨量异常检测方法,并针对城区居民的生活环境特点进行系统规范的骨量减少危险因素干预,是预防和控制骨质疏松发生的关键。     

2011年河南地区部分50岁以上人群骨质疏松性骨折发病特点初步研究

目的 了解2011年河南地区至我院就诊的骨质疏松性骨折患者的发病特点,为骨质疏松性骨折的防治提供理论依据。方法 回顾性分析我院2011. 1~2011. 12于骨科及急诊外科住院治疗骨质疏松性骨折患者（50岁以上）385例,男性127例,女性258例,并对年龄、性别、部位、所占比例进行统计分析。结果 50岁以上患者骨质疏松性骨折发生率随年龄增长而增加,79岁达高峰,女性发病率 明显高于男性;385例患者中髋部骨折187例(占骨折总数的48.57% ),脊柱骨折174例(占骨折总数 的45. 19% ),腕部骨折6例(占骨折总数的1.56% ),其他部位骨折18例(占骨折总数的4. 68% )。结论2011年河南地区50岁以上人群骨质疏松性骨折主要以髋部及椎体为主,女性发病率明显高于男性,应加强防治。     

上海市闵行区中老年群体中不同骨密度人群的尿钙水平调查分析

目的探索上海市闵行区中老年人群钙营养状况及其与骨质疏松的相关性。方法对长期居住在上海闵行区的50岁以上的1460例体检人群进行问卷调查和体格检查,DXA测定腰椎、总髋、股骨颈和Ward三角区的骨密度,化学发光法测定空腹血钙、尿钙。根据WHO标准诊断骨量正常、减少和疏松,尿钙低于1.7 mmol/L为缺钙,骨质疏松尿钙高于5.3 mmol/L为高尿钙流失,其余为正常尿钙水平。结果 1460人中,骨质疏松人数为337人,占总人数的23.08%,骨量正常人数为420人,占总人数的28.77%。其中男性骨质疏松率为4.12%,女性骨质疏松率为37.88%。尿钙水平偏低人数为365人,占总人数的25.0%,高尿钙水平人数为176人,占总人数的12.1%。其中男性尿钙水平偏低率为30.32%,女性尿钙偏低率为22.78%。尿钙水平值以60岁以下骨量减少组3.67 mmol/L最高。三年尿钙水平变化值以女性骨质疏松组差异最显著(P0.05)。结论缺钙率女性略低于男性群体,但骨质疏松率女性远远高于男性。老年群体中缺钙为普遍现象,缺钙外加高钙流失是导致老年性骨质疏松的主要因素。骨质疏松干预过程中,除补钙外,采取有效防治钙流失的措施是防治骨质疏松的关键。     

吉林省老年人群周围骨骨矿含量测定结果分析

目的通过测定所得骨矿含量数值更好的评估骨强度,监测骨质疏松的发生、发展,提高高危患者骨折风险识别能力。方法选取吉林省2375例50—89岁体检者运用美国OSTEOMETER DTX200周围骨骨密度测量仪测量受检者非受力侧前臂桡尺骨远端三分之一处的骨密度、骨矿含量,应用采用SPSS 17.0软件分析处理,数据用X±S表示。进行统计分析。结果男性50～59岁年龄组OP发生率为9.33%,女性为7.38%;60～69岁男性OP发生率为18.59%,女性为26.26%;70～79岁男性OP发生率为40.00%,女性为55.90%;80岁以上男性OP发生率63.93%,女性为71.42%。结论提示随着年龄增加,男女骨密度及BMC均呈下降趋势,女性下降速度明显较男性快,OP发生率也随之增加,各年龄组之间OP发生率女性亦均高于男性;T值大于-1的受检者中有5.74%骨量丢失率在13%～24%之间,亦为骨量减少范围,这类人群远期骨质疏松症的发病率及骨折的发生率很高,故骨矿含量(BMC)在临床骨质疏松症的诊断、治疗、预防骨质疏松骨折发生等方面起着重要作用。     

吸烟与男性骨质疏松关系的调查分析

目的 探讨吸烟与男性骨质疏松的关系。方法 对2012年3月～2012年10月在中南大学湘雅三医院 健康管理中心进行健康体检的资料完整的年龄20岁以上的男性人群进行回顾性研究,分别记录受检者骨质 疏松及相关危险因素的检测结果及问卷调查的结果。结果 在资料完整的2480例体检人群中低骨量、骨质 疏松检出率分别为44.9%和22.7%。吸烟量、烟龄及低体重指数与男性骨质疏松呈显著正相关(P<0．00)。 结论 男性骨质疏松发生率高,骨质疏松随着吸烟量、烟龄的增加及体重指数的降低而增加,预防骨质疏 松应提倡戒烟。     

社区健康体检人群生活行为方式与骨密度相关性研究.

目的研究不同性别和年龄的健康体检人群生活行为方式与群骨密度(bone mineral density,BMD)变化规律的相关性。方法采用Sahara临床超声骨密度仪对桂林市秀峰区2015年1月-2015年10月4185名社区健康体检人群跟骨进行BMD测定,结合生活行为方式调查问卷结果对相关数据进行统计分析。结果检测结果显示BMD正常者占66%,BMD异常者占34%;其中骨质疏松症(osteoporosis,OP)占2.29%,女性BMD正常率低于男性,OP发病率女性为2.72%,男性为1.91%;男性和女性BMD减少均多见于40岁以上中老年人群。生活行为方式调查结果显示不良的生活方式人群中BMD异常人群占68%,Logitics相关分析OR值为4.85(95%置信区间为3.14~6.83),结果具有统计学意义(P0.005)。结论健康人群不良的生活习惯是引起BMD异常导致OP发生的关键危险因素。因此,通过科学合理的的生活方式合并坚持良好的生活行为习惯,是预防OP发生的最佳措施。     

Epidemiologie der Extremitätenfrakturen

To analyze age- and sex-specific frequencies of peripheral fractures, we used data from the third MONICA-Augsburg Survey (1994/95). The study comprises 2404 male and 2450 female participants (age 25 to 74 years) who were questioned regarding fracture history. We investigated fracture prevalence, age-specific incidence rates, and the circumstances under which the fractures occurred. The age-standardized, cumulative fracture prevalence among men (m) 25 to 74 years of age was 45% and among women (w) of the same age 31%. Fracture prevalence among women was more than 10% lower than among men in the younger age groups (age 25 to 64 years), but after an significant increase in the 65 to 74-year-olds the fracture prevalence corresponded to that of men (m: 42%, w: 40%). A peak of incidence rates was found among men at age 15-24 (overall incidence rate: 2017 fractures/100,000 person-years) and at age 45-54 (overall incidence rate: 1640 fractures/100,000 PY), respectively, and among women at age 65-74 (overall incidence rate: 3214 fractures/100,000 PY). The prevalence of self-reported osteoporosis (age 25 to 74 years) was higher in women (7%) than in men (1%). Falls caused 43% (w: 59%, m: 33%) of all fractures, external violence 40% (m: 47%, w: 29%), and sports activities 15% (m: 18%, w: 10%). Further investigation of risk factors related to fractures can contribute to the development of specific preventive measures in that field. In the future, the prevention and efficient treatment of an existing or an often undiagnosed osteoporosis and also the prevention of falls in elderly persons should be an important public health concern.     

814例绝经后女性初潮年龄、绝经年龄及月经维持年限与骨质疏松症相关性研究

目的调查了解广州市社区绝经后妇女的生理因素对骨质疏松症的患病率及骨密度(BMD)的影响,为围绝经期女性骨质疏松的预防提供进一步证据。方法采用现场问卷调查了解受试者的基本资料,美国双能X线骨密度仪测量1199例绝经后女性的腰椎正位和左髋部骨密度,以年龄分组进行分析。结果共纳入的814名绝经后妇女当中,腰椎发生骨质疏松症300例,发生率36.9%;髋部发生骨质疏松的312例,发生率38.3%。绝经年限10年内的妇女中,初潮年龄较晚的骨密度越低,发生骨质疏松的风险越高; 55～65岁的绝经后妇女中,绝经年龄较早的骨密度越低,骨质疏松发生的风险越高;月经维持的年限越短,骨密度越低,发生骨质疏松的风险越高。结论广州市社区中绝经后妇女的骨质疏松患病率较高,初潮年龄较晚、绝经年龄较早或月经维持年限较短的妇女骨质疏松的发病率明显升高,建议早筛查、早诊断、早治疗。髋部BMD值是评价骨质疏松症较为敏感的指标,应该首选髋部作为骨密度测量的部位。     

Low calcaneal bone mineral density and the risk of distal forearm fracture in women and men: A population-based case-control study

ObjectiveWe used dual X-ray absorptiometry (DXA) to measure calcaneal bone mineral density (BMD) and estimate the prevalence of osteoporosis in a population with distal forearm fracture and a normative cohort.MethodsPatients 20 to 80 years of age with distal forearm fracture treated at one emergency hospital during two consecutive years were invited to calcaneal BMD measurement; 270 women (81%) and 64 men (73%) participated. A DXA heel scanner estimated BMD (g/cm²) and T-scores. Osteoporosis was defined as T-score ≤? 2.5 SD. Of the fracture cohort, 254 women aged 40–80 years and 27 men aged 60–80 years were compared with population-based control cohorts comprising 171 women in the age groups 50, 60, 70 and 80 years and 75 men in the age groups 60, 70, and 80 years.ResultsIn the fracture population no woman below 40 years or man below 60 years of age had osteoporosis. In women aged 40–80 years the prevalence of osteoporosis in the distal forearm fracture cohort was 34% and in the population-based controls was 25%; the age-adjusted prevalence ratio (PR) was 1.32 (95% CI 1.00–1.76). In the subgroup of women aged 60–80 years the age-adjusted prevalence ratio of osteoporosis was 1.28 (95% CI 0.95–1.71). In men aged 60–80 years the prevalence of osteoporosis in the fracture cohort was 44% and in the population-based controls was 8% (PR 6.31, 95% CI 2.78–14.4). The age-adjusted odds ratio for fracture associated with a 1-SD reduction in calcaneal BMD was in women aged 40–80 years 1.4 (95% CI 1.1–1.8), in the subgroup of women aged 60–80 years 1.2 (95% CI 0.95–1.6), and in men aged 60–80 years 2.6 (95% CI 1.7–4.1). Among those aged 60–80 years the area under the ROC curve was in women 0.56 (95% CI 0.49–0.63) and in men 0.80 (95% CI 0.70–0.80).ConclusionsThe age-adjusted prevalence of osteoporosis based on calcaneal BMD is higher in individuals with distal forearm fracture than in population-based controls. BMD impairment is associated with increased odds ratio for forearm fracture in both women and men but the differences between cases and controls are more pronounced in men than in women, which may have implications in fracture prevention.     

Estimating the excess costs for patients with incident fractures, prevalent fractures, and nonfracture osteoporosis

Summary

Based on a population age 50+, significant excess costs relative to matched controls exist for patients with incident fractures that are similar in relative magnitude to other chronic diseases such as stroke or heart disease. Prevalent fractures also have significant excess costs that are similar in relative magnitude to asthma/chronic obstructive pulmonary disease.

Introduction

Cost of illness studies for osteoporosis that only include incident fractures may ignore the long-term cost of prevalent fractures and primary preventive care. We estimated the excess costs for patients with incident fractures, prevalent fractures, and nonfracture osteoporosis relative to matched controls.

Methods

Men and women age 50+ were selected from administrative records in the province of Manitoba, Canada for the fiscal year 2007–2008. Three types of cases were identified: (1) patients with incident fractures in the current year (2007–2008), (2) patients with prevalent fractures in previous years (1995–2007), and (3) nonfracture osteoporosis patients identified by specific pharmacotherapy or low bone mineral density. Excess resource utilization and costs were estimated by subtracting control means from case means.

Results

Seventy-three percent of provincial population age 50+ (52 % of all men and 91 % of all women) were included (121,937 cases, 162,171 controls). There were 3,776 cases with incident fracture (1,273 men and 2,503 women), 43,406 cases with prevalent fractures (15,784 men and 27,622 women) and 74,755 nonfracture osteoporosis cases (7,705 men and 67,050 women). All incident fractures had significant excess costs. Incident hip fractures had the highest excess cost: men $44,963 (95 % CI: $38,498–51,428) and women $45,715 (95 % CI: $36,998–54,433). Prevalent fractures (other than miscellaneous or wrist fractures) also had significant excess costs. No significant excess costs existed for nonfracture osteoporosis.

Conclusion

Significant excess costs exist for patients with incident fractures and with prevalent hip, vertebral, humerus, multiple, and traumatic fractures. Ignoring prevalent fractures underestimate the true cost of osteoporosis.     

Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA

Summary Application of the WHO fracture prediction algorithm in conjunction with an updated US economic analysis indicates that osteoporosis treatment is cost-effective in patients with fragility fractures or osteoporosis, in older individuals at average risk and in younger persons with additional clinical risk factors for fracture, supporting existing practice recommendations. Introduction The new WHO fracture prediction algorithm was combined with an updated economic analysis to evaluate existing NOF guidance for osteoporosis prevention and treatment. Methods The WHO fracture prediction algorithm was calibrated to the US population using national age-, sex- and race-specific death rates and age- and sex-specific hip fracture incidence rates from the largely white population of Olmsted County, MN. Fracture incidence for other races was estimated by ratios to white women and men. The WHO algorithm estimated the probability (%) of a hip fracture (or a major osteoporotic fracture) over 10 years, given specific age, gender, race and clinical profiles. The updated economic model suggested that osteoporosis treatment was cost-effective when the 10-year probability of hip fracture reached 3%. Results It is cost-effective to treat patients with a fragility fracture and those with osteoporosis by WHO criteria, as well as older individuals at average risk and osteopenic patients with additional risk factors. However, the estimated 10-year fracture probability was lower in men and nonwhite women compared to postmenopausal white women. Conclusions This analysis generally endorsed existing clinical practice recommendations, but specific treatment decisions must be individualized. An estimate of the patient’s 10-year fracture risk should facilitate shared decision-making. The authors comprise the National Osteoporosis Foundation Guide Committee.     

应用双能X线骨密度仪对辽宁地区正常人群骨密度的流行病学调查

目的 调查辽宁地区正常人群骨密度值及骨质疏松患病率，为骨质疏松的预防提供科学依据。方法 对辽宁地区一般人群随机抽样2300例，应用美国Lunar公司生产的双能X线骨密度仪分别测试受试的L2－4及股骨上段（包括股骨颈，Ward's区及粗隆部位）的BMD值。结果 各检测组的BMD峰值均出现于20－29岁组，且BMD随年龄增加而逐渐降低，进入50－59岁组，女性的骨量丢失速度明显加快，尤以Ward's区明显。60－69岁年龄组的骨质疏松症患病率，男性为27％，女性为46．8％。结论 BMD随年龄增长而下降，骨质疏松发病率也随之增加，女性发病率明显高于男性。     

Fracture Rates and Fracture Risk in Patients With Marfan Syndrome: A Nationwide Register-Based Cohort Study

Marfan syndrome (MFS), a rare genetic disease, has a prevalence of 6.5 in 100,000. Studies show that patients with MFS have reduced areal bone mineral density (BMD) compared with non-MFS individuals. We have previously shown that patients with MFS have reduced volumetric BMD and compromised trabecular and cortical bone microarchitecture. The present study was a registry-based, nationwide, population-based, cohort study using register data, aimed to evaluate fracture risk and fracture rates in MFS. We included 406 (196 women) patients with MFS through the Danish National Patient Register and 40,724 (19,327 women) persons, randomly selected and matched from the Civil Registry System. A total of 21.9% of the MFS and 18.9% of the reference population had experienced at least one fracture from 1995 to 2018. The fracture incidence rate was 27.5 per 1000 person-years in the MFS cohort (highest in young men and old women with MFS), and 20.3 per 1000 person-years in the reference population. The overall incidence rate ratio between the MFS and the reference population was 1.35 (95% confidence interval [CI ] 1.18–1.55) for all fractures. When evaluating the risk of being registered with an osteoporosis diagnosis in the Danish National Patient Register, starting relevant treatment for osteoporosis or experiencing a hip or spine fracture, 10.3% of the MFS cohort and 3.3% of the reference population could be classified as being osteoporotic. The between-group subhazard ratio was 3.97 (95% CI 2.56–6.25). Patients with MFS started treatment with an antiosteoporotic drug at a younger age than the reference population (57 [interquartile range 55–67] versus 71 [63–73]) years. The life expectancy in MFS is increasing, resulting in more patients facing diseases that are related to old age, such as age-related bone loss and increased risk of fractures. Our data suggest that bone health and fracture prevention needs to be part of the standard care for patients with MFS. © 2021 American Society for Bone and Mineral Research (ASBMR).     

Epidemiology of fractures of the proximal femur in Geneva: Incidence,clinical and social aspects

Fracture of the proximal femur (hip fracture) as a consequence of osteoporosis is an important public health problem. Its incidence, which rises with age, varies according to geographical location and race. There is no information concerning hip fracture in Switzerland, which is a Western country with a particularly aged population. During 1987, 361 patients with hip fracture were recorded in the University of Geneva Hospital, which is the main referral center for a population of about 376000 inhabitants. This represented 94% of all hip fractures occurring in the region. A moderate trauma was reported in 329 cases (91.1%). The overall annual incidence was 96.1 per 100000 population (146.9 for women and 39.8 for men). When only hip fractures following moderate trauma were considered, the incidence was 87.6 per 100000 population (138.8 for women and 30.8 for men). Rare under the age of 65, hip fracture incidence increased exponentially in older subjects. The mean age of patients with hip fracture was 82.0 years in women and 75.7 years in men. The ratio of cervical to trochanteric fracture was 1.03 and 1.12 in women and men, respectively. The mean length of stay in the orthopaedic ward was 30.5 days, and the total costs amounted to 8.8 million Swiss francs for hip fracture associated with moderate trauma. Forty-seven percent of subjects were transferred to another hospital for recovery or rehabilitation. During the stay in the orthopaedic ward, the mortality rate was 8.2%. These results emphasize the high incidence and cost of hip fractures in a region of Switzerland where the population is particularly old. The problem could even worsen with the progressive aging of the population.     

产后早期妇女骨质疏松相关因素分析

目的：了解产后早期妇女骨量丢失的影响因素,为防止妊娠有关的骨质疏松发生提供依据。方法纳入在我院分娩的产后10～14天妇女1125例,采用双能X线骨密度测定仪测定受试者L1-L4椎体及左侧股骨颈的骨密度（BMD）,根据骨密度分为骨质疏松组、骨量减少组、骨量正常组,比较各组间年龄、身高、体重指数（ BMI）、产次、钙摄入量等差异。结果在1125例调查者中,骨质疏松65例（5.8％）,骨量减少429例（38.1％）,骨量正常631例（56.1％）。牛奶摄入量每天＞200 ml的产妇,其骨质疏松发生率低于牛奶每天摄入＜200 ml的产妇（ P＜0.01）。孕期补钙的产妇骨质疏松发生率低于未补钙者（ P＜0.01）,有骨质疏松家庭史的产妇,其骨质疏松发生率高于无骨质疏松家庭的产妇（P＜0.01）。结论产后妇女骨质疏松及骨量减少的发生率较高,骨质疏松家族史、钙摄入不足、低BMI是产后骨量丢失的风险因素,产后常规测量骨密度有助于骨质疏松的早期诊断及治疗。