LPHP治疗老年肱骨近端粉碎骨折

目的：探讨应用肱骨近端锁定钢板治疗老年肱骨近端粉碎骨折的疗效。方法：2004年4月-2009年8月我科使用肱骨近端锁定钢板治疗肱骨近端粉碎骨折51例,患者年龄60～83岁,平均65岁。骨折按Neer分型,2部分骨折18例,3部分骨折27例,4部分骨折6例。结果：51例均获随访,随诊5—24个月,平均14个月,所有患者均获骨性愈合。肩关节功能按Neer疗效评分系统评定,优34例,良13例,可4例,优良率为92．2％。结论：锁定加压钢板治疗老年人肱骨近端骨折疗效满意,是治疗老年人肱骨近端骨折较合适有效的内固定方法。     

肱骨近端锁定钢板治疗肱骨近端骨折的疗效

探讨应用肱骨近端锁定钢板治疗肱骨近端骨折的疗效。方法肱骨近端骨折46例根据Neer分型:二部分骨折17例,三部分骨折26例,四部分骨折3例。均使用肱骨近端锁定钢板治疗,术后行系统化康复训练,按Neer评分标准评定疗效。结果全部病例获8～16个月随访,骨折均愈合,平均临床愈合时间4.2个月(3～5个月)。46例中优24例,良15例,可5例,差2例,优良率达84.8%。结论肱骨近端锁定钢板是治疗肱骨近端骨折的一种理想选择,只要正确操作,可以获得较满意的临床效果。     

锁定钢板治疗肱骨近端骨折临床分析

目的探讨应用肱骨近端锁定钢板治疗中老年患者肱骨近端骨折的疗效。方法回顾性分析我院近年来收治的中老年患者的临床资料。结果 2006年4月～2010年8月使用肱骨近端锁定钢板治疗肱骨近端骨折54例,年龄45～81岁;平均54岁。骨折按Neer分型：2部分骨折15例,3部分骨折28例,4部分骨折11例,均予肱骨近端锁定钢板内固定。41例获随访,随诊6～24个月,平均14个月。均获骨性愈合,平均愈合时间4.8个月。肩关节功能按Neer疗效评分系统评定,优24例,良16例,可1例,差1例,优良率93.5%。结论锁定加压钢板治疗中老年患者肱骨近端骨折疗效满意,是目前治疗肱骨近端骨折较理想的内固定方法。只要重视肩袖损伤的修复,术后,早期进行功能锻炼,抗骨质疏松治疗,功能恢复良好。     

锁定钢板治疗肱骨近端复杂性骨折

目的 探讨锁定钢板治疗肱骨近端复杂性骨折的临床疗效.方法 选择2007年1月～2009年12月采用肱骨近端锁定钢板治疗肱骨近端骨折36例,骨折按Neer分类:三部分骨折25例,四部分骨折11例.均采用切开复位肱骨近端锁定钢板内固定.结果 36例均获得随访(9～24个月),所有病例均一期愈合,平均骨折愈合时间为9.5周.无一例内固定松动或肱骨头坏死.按Neer评分:优21例,良12例,可3例,优良率91.7%.结论 肱骨近端锁定钢板治疗肱骨近端复杂性骨折,操作简单,内固定坚强,效果满意.     

锁定钢板治疗老年肱骨近端骨折

目的探讨锁定钢板内固定治疗老年肱骨近端骨折的疗效。方法 16例老年肱骨近端患者采用锁定钢板内固定治疗,按照Neer评定标准评价疗效。结果 16例患者骨折均愈合,随访时间为4个月~2年,平均7个月。采用Neer百分制评定标准评定,优10例,良4例,可2例,优良率为87.5%.结论锁定钢板内固定对老年人肱骨近端骨折固定牢靠,疗效满意,是理想的治疗方法。     

锁定加压钢板内固定治疗肱骨近端骨折

目的:探讨肱骨近端锁定钢板治疗肱骨近端骨折的疗效。方法:回顾性分析2007年3月-2011年3月应用解剖锁定钢板内固定治疗36例肱骨近端骨折患者的资料。结果:36例患者术后随访8~28个月,平均18个月,骨折均获愈合。愈合时间为12~20周,平均14.6周。根据Neer功能评定标准:优18例,良15例,可3例,优良率91.67%。结论:锁定加压钢板治疗肱骨近端骨折,手术内固定牢靠,并发症少,骨折愈合率高,有利于早期功能锻炼。     

肱骨近端锁定钢板治疗老年肱骨近端骨折

目的探讨锁定钢板治疗老年人肱骨近端骨折的临床疗效。方法从2007年4月至2010年4月,应用肱骨近端锁定钢板治疗老年肱骨近端骨折13例。其中,Neer二部分骨折4例,三部分骨折7例,四部分骨折2例。结果术后平均随访6个月,所有病例无骨折不愈合,Neer肩关节功能评分：优5例,良4例,优良率为69.2%。结论肱骨近端锁定钢板内固定可靠,利于术后早期功能锻炼,为老年骨质疏松病人肱骨近端骨折治疗的良好选择。     

锁定钢板治疗肱骨外科颈骨折临床分析

目的 探讨锁定钢板治疗肱骨近端复杂骨折的临床疗效.方法 2008年2月-2011年4月使用端锁定钢板治疗肱骨近端骨折36例,年龄35-78岁;平均51岁.骨折按Neer分型:2部分骨折16例,3部分骨折14例,4部分骨折6例,伴肩关节脱位5例,均予肱骨近端锁定钢板内固定.结果 36例均获随访,随访5-36月,平均21个月.均获骨性愈合,平均愈合时间为4.7个月,无1例发生内固定松动,Neer肩关节功能评分标准.优良率88.89%.结论 锁定钢板是治疗肱骨外科颈骨折的一种优异的内固定方法.     

肱骨近端锁定钢板内固定治疗肱骨近端骨折

目的探讨锁定钢板治疗肱骨近端骨折的固定策略及疗效。方法回顾分析行锁定钢板治疗32例肱骨近端骨折患者资料,根据Neer分型:二部分骨折11例,三部分骨折15例,四部分骨折6例。采用三角肌胸大肌间沟入路,行肱骨近端锁定钢板内固定。结果本组32例患者术后获得5个月～2年(平均11.2个月)的随访,骨折均获得临床愈合,愈合时间8～20周(平均12.6周)。肩关节功能根据Neer功能评分标准评定:优25例,良4例,可2例,差1例,优良率为90.6%,1例术后发生肱骨头坏死。结论肱骨近端锁定钢板内固定治疗肱骨近端骨折可以取得良好疗效。操作时需注意保护肱骨头血运,骨折尽可能解剖复位,重建肱骨颈内侧支撑,骨缺损时植骨,这样可以提高疗效,减少并发症的发生。     

锁定钢板固定治疗肱骨近端骨折

目的研究和分析锁定钢板在肱骨近端骨折治疗中的应用价值。方法对26例肱骨近端骨折行切开复位肱骨近端锁定钢板（LPHP）内固定,并分析疗效。结果26例患者术后随访6～18个月,平均12个月,骨折均愈合,平均愈合时间5个月。按Neer评分标准评定,总优良率88％。结论LPHP治疗肱骨近端骨折疗效满意。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.