膝关节镜下半月板全切与部分切除对骨密度及下肢力线的影响

目的探讨膝关节镜下半月板全切与部分切除对骨密度及下肢力线的影响。方法选择2010年1月至2011年12月单侧外侧半月板损伤实施膝关节镜手术患者100例,随机分为两组：对照组50例进行关节镜下单侧半月板全切术,观察组50例则实施关节镜下单侧半月板部分切除术,比较两组膝关节周围骨密度及下肢力线变化。结果术后随访2年,观察组患侧膝关节周围骨密度显著优于对照组[（-1.42±0.15）g/cm2vs（-2.54±0.36）g/cm2,P〈0.01],观察组患侧下肢力线显著优于对照组[（8.51±1.24）mm vs（13.52±1.31）nm,P〈0.01]。结论对于膝关节半月板损伤患者,应尽量保留半月板,避免实施全切术,以减少对膝关节周围骨密度和下肢力线的影响。     

关节镜下外侧盘状半月板切除范围对单侧盘状半月板损伤患者下肢力线及膝关节功能的影响

目的探讨关节镜下外侧盘状半月板切除术中外侧盘状半月板切除范围对单侧盘状半月板损伤患者下肢力线及膝关节功能的影响。方法选择2016年2月至2017年2月无锡市第三人民医院收治的85例单侧盘状半月板损伤患者为研究对象,患者均接受关节镜下外侧盘状半月板切除术治疗,根据外侧盘状半月板切除范围分为A组(40例)和B组(45例),A组患者术中外侧盘状半月板切除范围≥1/2,B组患者外侧盘状半月板切除范围<1/2。所有患者术后随访2 a,分别于术前、术后1个月及术后1、2 a测量患者下肢力线(固有偏距),并进行膝关节功能Lysholm评分和国际膝关节文献委员会(IKDC)评分。结果 2组患者术前下肢力线(固有偏距)比较差异无统计学意义(P> 0. 05); 2组患者术后1个月及术后1、2 a下肢力线(固有偏距)均小于术前(P <0. 05),2组患者术后1、2 a下肢力线(固有偏距)均小于术后1个月(P <0. 05),2组患者术后2 a下肢力线(固有偏距)均小于术后1 a(P <0. 05);术后1个月及术后1、2 a,B组患者下肢力线(固有偏距)均小于A组(P <0. 05)。2组患者术前膝关节功能Lysholm评分、IKDC评分比较差异均无统计学意义(P> 0. 05); 2组患者术后1个月及术后1、2 a膝关节功能Lysholm评分、IKDC评分均高于术前(P <0. 05),2组患者术后1、2 a膝关节功能Lysholm评分、IKDC评分均高于术后1个月(P <0. 05); 2组患者术后2 a膝关节功能Lysholm评分、IKDC评分均高于术后1 a(P <0. 05);术后1个月及术后1、2 a,B组患者膝关节功能Lysholm评分、IKDC评分均高于A组(P <0. 05)。结论关节镜下外侧盘状半月板切除术中应尽量减少半月板切除范围,最大限度地保留正常半月板,以利于术后下肢力线和膝关节功能的恢复。     

早期康复对膝关节周围骨折术后关节功能恢复及骨密度的影响

目的探讨早期康复对膝关节周围骨折术后关节功能恢复及骨密度的影响。方法将我院住院治疗的80例膝关节周围骨折患者随机分为对照组与观察组各40例。对照组患者给予常规治疗措施,在术后3周后给予康复治疗,观察组患者在围手术期进行早期系统康复治疗,比较两组患者术后关节功能恢复及骨密度的变化。结果治疗后1个月观察组与对照组膝关节优良率分别为92．5％和77．5％,差异有统计学意义（P〈0．05）;治疗后3个月观察组膝关节Lysholm评分及关节活动度ROM均显著优于对照组（P〈0．05）;两组患者术后2个月检测腰椎、股骨骨密度较术前均下降,但观察组患者骨密度的减少量显著低于对照组（P〈0．05）。结论对膝关节周围骨折进行早期康复可减少骨密度减少量,促进关节功能恢复,改善患者预后。     

半月板桶柄样损伤的关节镜手术治疗

目的 探讨膝关节半月板桶柄样损伤的关节镜手术治疗效果和手术技巧.方法 2006年10月1日至2007年9月30日对31例34膝关节半月板损伤患者在进关节镜探查手术时,被确定为半月板桶柄样损伤,12例为内侧半月板,19例为外侧半月板,其中3例为双侧外侧半月板损伤.本组术前患者往往存在膝节疼痛、弹响或跛行等症状,MRI检查有助于术前分类诊断.其中25例行半月板部分切除成形术,5例因边缘撕裂行半月板次全切除术,1例行半月板合术.对这些患者的临床表现特点进行总结,并随访关节镜手术的近期疗效.结果 所有病例术后随访症状均明显改善或消失,无术后并发症.本组ysholm膝关节功能评分从术前35～62分,平均(41.7±4.1)分,术后6个月提高到86～100分,平均(95.6±3.3)分(t=24.52,P＜0.01).结论 膝关节半板桶柄样损伤患者症状明显,关节镜手术治疗效果良好,并发症少.     

骨小梁金属髋臼假体对人工全髋关节置换术后髋臼侧假体周围骨密度的影响

目的 比较骨小梁金属(TM)髋臼与钛合金金属(Ti)髋臼术后短期临床预后及髋臼侧骨密度(BMD)变化,观察TM对人工全髋关节术后髋臼侧骨质变化的影响.方法 随访TM组患者15例和Ti组患者13例,比较两组病例术后髋关节Harris评分;观察X线平片上髋臼假体与骨界面有无放射性透亮线,根据Hodgkinson系统予以分级;利用双能X线骨密度仪(DEXA)分别于髋臼Ⅰ、Ⅱ和Ⅲ区取直径为1 cm的圆形感兴趣区域(ROI)测量BMD.结果 两组病例术后髋关节Harris评分比较,差异无统计学意义(P＞0.05).所有病例Hodgkinson系统分级皆为0级,未见假体松动移位.DEXA测量结果显示:Ti组术后患侧髋臼假体周围所有ROI的BMD值较健侧均有明显下降(P ＜0.05);TM组术后患侧髋臼假体周围各ROI的BMD值与健侧比较,差异均无统计学意义(P＞0.05);两组间ROI Ⅰ区和Ⅱ区术后BMD变化比例的差异有统计学意义(P＜0.05),而两组间ROIⅢ区BMD变化比例的差异无统计学意义(P＞0.05).结论 TM髋臼和Ti髋臼对术后髋臼侧骨质保留有重要意义.     

关节镜下外内缝合法和全内缝合法治疗膝关节外侧盘状半月板损伤对术后疼痛及关节功能的影响

目的探讨关节镜下外内缝合法和全内缝合法治疗膝关节外侧盘状半月板损伤对术后疼痛和关节功能的影响。方法随机抽选2019年1月至2020年12月郑州市骨科医院接收的80例膝关节外侧盘状半月板损伤患者,按照随机数字表法分为对照组与观察组各40例,分别实施关节镜下外内缝合法与关节镜下全内缝合法,对两组膝关节功能、手术相关指标、视觉模拟评分法(VAS)评分和Lysholm评分进行对比分析。结果对照组膝关节功能治疗优良率为90.00%,观察组为95.00%,两组比较差异无统计学意义(P0.05);对照组手术时间为(45.78±9.25) min,观察组为(36.32±8.47) min,观察组短于对照组(P0.05);两组术中出血量差异无统计学意义(P0.05);两组术前VAS评分和Lysholm评分差异无统计学意义(P0.05);术后,对照组分别为(3.15±0.79)分和(72.56±2.31)分,观察组分别为(2.32±0.47)分和(76.05±1.74)分,观察组均优于对照组(P0.05)。结论膝关节外侧盘状半月板损伤治疗过程中,关节镜下外内缝合法与关节镜下全内缝合法均具有显著效果,但是全内缝合法操作更加简单,其可以减少手术时间,减轻治疗疼痛程度,及早恢复膝关节功能,值得临床进一步采纳与推广。     

关节镜下手术治疗膝关节半月板损伤39例临床观察

目的观察关节镜下手术治疗膝关节半月板损伤的临床治疗效果。方法对39例膝关节半月板损伤患者(观察组)应用关节镜下手术治疗,根据半月板损伤的类型分别进行处理,术后随访观察;并与40例半月板全切除术患者(对照组)进行比较,采用Lysholm膝关节功能评分评价手术治疗效果。结果所有患者均获得随访,平均随访时间(13.5±3.6)个月(2～32个月);观察组Lysholm-Ⅱ评分术前平均(45.1±2.1)分,术后平均(90.7±12.5)分,对照组术前评分平均(45.0±2.3)分,术后平均(75.3±11.8)分,两组治疗效果具有统计学意义(P0.01)。结论关节镜下手术治疗膝关节半月板损伤能最大限度地保留半月板,创伤小,恢复快,疗效佳,有利于早期功能锻炼。     

犬HA涂层股骨柄结合自体颗粒骨移植后假体周围骨CT值评估

目的:从CT值的角度分析髓腔颗粒骨植骨对犬HA涂层股骨柄置换后股骨柄周围骨密度的影响。方法:24只健康成年杂种犬随机分为颗粒骨组和非颗粒骨组,每组各12只;均行右侧人工股骨柄置换术,实验组在植入HA涂层股骨柄的同时,髓腔植入自体微小颗粒骨,对照组不植入颗粒骨。术后应用16排螺旋CT扫描仪来测定并分析假体周围的CT值,随访时间为3个月。每个股骨测量70个CT值(每个股骨按照Gruen法,分为7个区,每区取10个点)组成数据集,采集数据时应用标准的CT软件ADW4.2观察并分析结果。结果:手术方式、术后时间对假体周围ROI1和ROI7(ROI:感兴趣区)CT值的影响没有显著差异,手术方式与术后时间也不存在交互作用,p值均大于0.05;手术方式与术后时间对ROI5,ROI6区CT值的影响均有显著性(p<0.05);ROI2,ROI3,ROI4随时间推移假体周围CT值均有不同程度的降低,差异有统计学意义(P<0.05),而手术方式对此三区术后CT值变化的影响不具有统计学意义。结论:3个月内2组股骨假体周围的大部分区域骨密度均呈进行性下降趋势,颗粒骨在假体周围某些区域可缓解股骨柄移植后的骨密度降低。骨CT值可间接反映骨密度的变化,CT测量准确便捷,可提供了大量三维CT值,适于进行骨密度的研究。     

全髋关节置换术后假体周围骨密度和 骨代谢的变化及其临床意义

目的 探讨全髋关节置换术后假体周围骨密度和骨代谢的变化及其临床意义。方法 前瞻性收 集该院收治的全髋关节置换术后患者128 例,测定患者术前、术后12 个月的骨密度和骨代谢水平,分析骨密 度和骨代谢水平与Harris 评分的相关性。结果 术后12 个月患者Harris 评分高于术前（P <0.05）。Pearson 线 性相关性分析显示,Harris 评分与感兴趣区域1（ROI 1）、ROI 7 骨密度呈正相关（P <0.05）。与术前比较, 术后12 个月ROI 1、ROI 2、ROI 3、ROI 5、ROI 6 和ROI 7 骨密度水平降低（P <0.05）;手术前后ROI 4 骨密度比较,差异无统计学意义（P >0.05）;术后12 个月抗酒石酸酸性磷酸酶5b 水平升高（P <0.05）。 结论 全髋关节置换术后假体周围骨密度降低,可能与骨破坏有关,可影响患者术后康复质量。     

Arthroscopic meniscectomy of discoid lateral meniscus in adolescents

目的 探讨关节镜下半月板成形术治疗青少年盘状半月板的疗效.方法 自2005年1月至2010年12月,关节镜下治疗43例(47膝)膝关节盘状半月板损伤患者,男25例,女18例；平均年龄16.5±4.6岁；左21例,右26例,双膝4例；内侧盘状半月板3例,外侧盘状半月板44例,术前病程13.6±3.9月.结果 术后平均随访27.3±8.9月(16 ～ 58月),Ikeuchi 膝关节功能评分标准,优41例(87.2％),良2侧(4.3％),可4例(8.5％),差0例.术前lysholm评分32～75 (61.2±11.4)分,终末随访时89 ～ 100( 96.3±4.5)分,较术前有显著提高(t=19.634,P＜0.01).结论 关节镜下治疗青少年盘状半月板疗效满意；早期治疗有利于减少骨关节炎的发生.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.