双黄连超声雾化吸入治疗急性咽炎疗效观察

目的观察双黄连超声雾化吸入治疗急性咽炎的临床疗效。方法将172例急性咽炎患者随机分为治疗组和对照组(各86例),治疗组应用双黄连超声雾化吸入,对照组应用庆大霉素,地塞米松超声雾化吸入。结果治疗组疗效明显优于对照组(P<0.01)。结论双黄连雾化吸入治疗急性咽炎效果较好,值得临床推广。     

不同雾化方式对COPD患者舒适度的影响

目的:探讨适用于慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者理想的舒适度的雾化吸入方法。方法:采用随机数字表法将60例COPD患者分为压缩空气雾化组与超声雾化组,各30例,分别采用压缩空气驱动雾化吸入和超声雾化吸入,比较两组患者雾化吸入治疗前后患者舒适度改变;经皮血氧饱和度(pulse oxygensaturation,SpO2)的改变;化痰咳痰效果情况。结果:雾化吸入后压缩空气雾化组患者舒适度改变、SpO2升高较超声雾化组患者明显(P<0.01);两组患者痰液是否容易咳出,化痰咳痰效果情况差异无统计学意义(P>0.05)。结论:压缩空气驱动雾化吸入对提高COPD患者舒适度、改善患者缺氧症状的效果优于超声雾化吸入,提示其为COPD患者较理想的雾化方法。     

空气压缩泵吸入与超声波雾化吸入治疗毛细支气管炎疗效观察

目的:探讨比较空气压缩泵吸入与超声波雾化吸入对小儿毛细支气管炎的治疗作用。方法:120例毛细支气管炎患儿被随机分为治疗组与对照组,各60例,两组均给予抗感染等常规治疗,同时,治疗组患者用空气压缩泵雾化吸入沙丁胺醇加布地奈德、异丙托溴铵;对照组用同种药物以超声雾化吸入器吸入治疗,观察病情变化。结果:治疗组加用空气压缩泵雾化吸入治疗效果更好,与对照组超声波雾化吸入比较疗效差异有统计学意义(P<0.01)。结论:在常规治疗基础使用空气压缩泵比超声雾化吸入治疗毛细支气管炎更有效。     

婴儿奶嘴在小儿超声雾化吸入中的临床应用

目的观察婴儿奶嘴在超声雾化吸入治疗中的依从性和治疗效果。方法将260例行雾化吸入的患儿分为观察组和对照组,各130例,观察组采用普通婴儿奶嘴代替超声雾化吸入器口含嘴进行雾化治疗,对照组进行常规操作。结果两组患儿雾化吸入治疗的依从性比较,差异有统计学意义(P<0.05),观察组优于对照组。两组患儿咳嗽明显减轻所用时间、呼吸困难消失所用时间、肺部痰鸣音消失的时间经比较,差异均有统计学意义(P<0.01),观察组疗效优于对照组。结论婴儿奶嘴代替口含嘴可提高婴幼儿雾化吸入的依从性;咳嗽、咳痰、呼吸困难等症状能在短期内明显改善。     

氧气驱动雾化吸入治疗小儿毛细支气管炎50例疗效观察及护理

目的:观察氧气驱动雾化吸入治疗小儿毛细支气管炎的疗效,总结护理经验。方法:两组患儿均采取包括吸氧、抗感染、止咳、平喘、化痰等综合性治疗和常规护理,观察组在上述治疗的同时,遵医嘱将普米克令舒1mg/2ml加生理盐水10ml注入氧气驱动雾化吸入器,高流量氧气4～6L/min形成气雾,雾化吸入5～10min,2次/d。对照组应用超声雾化吸入器,将同种药物加入药皿中雾化吸入15～20min,2次/d。结果:治疗5d后,观察组治愈率明显高于对照组,经统计学分析,两组间差异有统计学意义(P<0.05)。结论:氧气驱动雾化疗效优于常规超声雾化吸入。护理中操作要认真,观察病情要仔细,正确叩击患儿背部,使痰液排出,治疗顺利进行。     

硫酸特布他林雾化吸入治疗COPD急性发作观察

目的评价硫酸特布他林雾化吸入治疗慢性阻塞性肺疾病(COPD)急性发作的效果。方法将42例COPD急性发作期患者分成两组,治疗组22例给予硫酸特布他林0.25mg加入0.9%生理盐水4ml中雾化吸入;对照组20例口服博利康尼0.25mg。观察两组治疗前后临床症状和肺功能FEV1.0、FVC的变化情况。结果治疗组的咳嗽、喘息症状以及罗音消失时间均比对照组明显缩短(P<0.05或0.01);两组治疗前后肺功能各项指标均得到改善,但治疗组明显优于对照组(P<0.01或0.05)。结论COPD急性发作期雾化吸入特布他林能有效缓解支气管痉挛,改善患者的临床症状及通气功能。     

普米克令舒吸入佐治小儿喘息性支气管炎效果观察

目的观察普米克令舒超声雾化吸入佐治喘息性支气管炎的效果。方法76例喘息性支气管炎患儿随机分为两组,地塞米松雾化吸入对照组30例,普米克令舒雾化吸入治疗组46例。两组常规予以抗感染、抗病毒、吸氧等处理,治疗组在上述综合治疗基础上,加用普米克令舒雾化吸入,每日2次。观察两组治疗前后心率、呼吸频率变化及喘息缓解、喘鸣音、咳嗽消失时间。结果治疗组、对照组治疗前后心率、呼吸频率的变化差异均有显著性(P<0.05)。治疗组气促缓解、喘鸣音、咳嗽消失时间比对照组缩短(P<0.05或0.01)。两组治愈率差异有显著性(P<0.05)。结论普米克令舒超声雾化吸入是佐治喘息性支气管炎安全有效的方法之一。     

氧驱动雾化吸入布地奈德治疗急性感染性喉炎临床观察

目的观察局部雾化吸入布地奈德与全身应用糖皮质激素治疗小儿急性感染性喉炎的效果及不良反应。方法选择100例急性感染性喉炎患儿,随机分为治疗组和对照组各50例。治疗组在控制感染的基础上局部雾化吸入布地奈德,对照组在控制感染的基础上静脉应用地塞米松。结果治疗组总有效率高于对照组(P<0.05);喉鸣、声嘶、犬吠样咳嗽消失时间及住院时间均比对照明显缩短(P<0.05或P<0.01)。结论局部雾化吸入布地奈德治疗小儿急性感染性喉炎效果显著,使用方便、安全。     

COPD患者应用不同雾化吸入方法的疗效观察及护理

目的探讨不同雾化吸入方法对慢性肺阻塞性肺疾病(COPD)患者的疗效观察及护理。方法回顾性研究我院2010年2月开始收治的40例COPD患者,其中20例使用超声雾化吸入法进行治疗,为A组,20例进行氧气雾化吸入法进行治疗,为B组,探讨两组疗效,比较两组治疗前后的FEV1(第一秒用力呼气容积)、PaCO2(二氧化碳分压)、PaO2(血氧张力)、SpO2(氧饱和度)、PEF(峰值呼气流速)和患者前后的症状。结果氧气雾化吸入法治疗COPD患者效果安全,确切,患者治疗前后FEV1、PaCO2、PaO2、SpO2、PEF和症状得到改善,比超声雾化吸入法效果更好,两组数据具有明显差异性(P<0.05),而且操作简单,患者易于接受。结论氧气雾化吸入法更适合COPD患者,同时配合系统的护理措施,可取得良好的治疗效果。     

病毒唑雾化吸入治疗呼吸道合胞病毒感染的效果分析

目的观察病毒唑雾化吸入给药方式治疗呼吸道合胞病毒感染的效果。方法将120例12岁以下的呼吸道合胞病毒感染的患儿随机分成两组(每组60例),在同样治疗基础上,治疗组采用病毒唑超声雾化吸入,对照组采用病毒唑静脉滴注。结果治疗组疗效明显优于对照组(P<0.01),主要体征和体征持续时间比对照组明显缩短(P均<0.01)。结论采用病毒唑超声雾化吸入治疗呼吸道合胞病毒感染效果优于静脉给药。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.