推拿针灸联合口服独一味胶囊治疗退行性膝关节炎临床观察

目的观察推拿针灸联合口服独一味胶囊治疗退行性膝关节炎的疗效。方法将42例退行性膝关节炎患者患者随机分成2组。治疗组22例,采用推拿针灸配合独一味胶囊内服疗法,每天推拿针灸1次并加口服独一味胶囊治疗。对照组20例,采用口服独一味胶囊治疗。同时2疗程后分别观察2组关节疼痛、肿胀及功能改善情况。结果治疗组治愈率为59%,有效率为95.45%;对照组治愈率为50%,有效率为85%。2组有效率和治愈率比较,差异有统计学意义(P0.05、P0.025)。结论表明推拿针灸联合口服独一味胶囊疗法治疗退行性膝关节病,止痛、消除关节肿胀效果良好,疗效明显优于单纯中药内服疗法。     

推拿配合功能锻炼治疗膝骨性关节炎40例的临床观察

目的：观察推拿配合功能锻炼治疗膝骨性关节炎的临床疗效。方法：80例随机分为治疗组40例和对照组40例,治疗组采用推拿配合功能锻炼治疗,对照组采用注射玻璃酸钠治疗。结果：治疗组有效率95%,其中临床控制25例,显效8例,有效5例,无效2例;对照组总有效率85%例,其中临床控制18例,显效10例,有效6例,无效6例。两组比较有显著差异（P〈0.05）。结论：推拿配合功能锻炼治疗膝骨性关节炎的疗效优于采用注射玻璃酸钠治疗,明显缓解关节疼痛及恢复关节功能。     

中西医结合治疗退行性膝关节炎37例

目的：观察中西医结合治疗退行性膝关节炎的临床疗效。方法：73例退行性膝关节炎患者随机分为治疗组37例、对照组36例,对照组采用西药治疗,治疗组在对照组治疗基础上加用中药熏洗及局部外敷治疗。1疗程后评定疗效。结果：总有效率治疗组91.89%,对照组77.78%,两组疗效经统计学处理,有显著性差异（P〈0.05）。结论：中西医结合治疗退行性膝关节炎效果较好。     

温针灸配合温阳通痹中药治疗退行性膝关节炎疗效观察

目的：观察温针灸配合温阳通痹中药治疗退行性膝关节炎的临床疗效。方法：选择120例退行性膝关节炎患者纳入观察,将其随机分为治疗组（60例）与对照组（60例）。治疗组给予温针灸配合温阳通痹中药口服,对照组予温阳通痹中药口服。疗程均为14d。结果：经治疗,治疗组临床治愈13例,显效23例,有效17例,总有效率为88．3％;对照组临床治愈6例,显效18例,有效19例,总有效率为71．7％。治疗组疗效优于对照组,差异有统计学意义（P〈0．05）。结论：温针灸配合温阳通痹中药治疗退行性膝关节炎疗效确切,值得临床推广使用。     

理疗配合手法治疗退行性膝关节炎临床观察

目的观察理疗配合手法治疗退行性膝关节炎的疗效。方法：将190例患者随机平均分为治疗组和对照组,治疗组采用理疗配合膝关节手法治疗,对照组采用超短波和电脑中频治疗。结果与结论：治疗组治愈率为86.3%,对照组为46.3%,两组有显著性差异（P〈0.05）,说明理疗配合手法治疗退行性膝关节炎疗效好。两组1年后复发情况统计说明,治疗组比对照组复发率低（P〈0.05）,远期疗效较好。     

温针配合推拿治疗重度膝关节炎的护理体会

目的:探讨采用温针配合推拿治疗重度膝关节炎的护理体会,为今后临床重度膝关节炎患者的护理提供科学的指导。方法:收治的200例重度膝关节患者作为观察对象,随机分为试验组100例和对照组100例。试验组采用温针配合推拿治疗重度膝关节炎护理,对照组采用温针治疗护理,对比两组护理后治疗效果以及患者满意度。结果:试验组总有效率为94.0%;对照组总有效率为76.0%,两组比较,差异具有统计学意义(P<0.05);实验组患者满意度为95.0%,对照组患者满意度为70.0%,两组比较,差异有统计学意义(P<0.05)。结论:在治疗重度膝关节炎过程中,实施温针配合推拿治疗重度膝关节炎的治疗及护理,能显著提高患者治疗效果和患者满意度,有助于患者早日康复,提升患者生活质量。     

腕踝针配合推拿疗法治疗膝骨性关节炎

目的观察腕踝针配合推拿疗法治疗膝骨性关节炎的临床疗效。方法将64例膝骨性关节炎的患者随机分成治疗组和对照组,各32例。治疗组给予腕踝针和推拿治疗(1次/d,每周治疗5天,休息2天,共治疗4周),对照组给予塞来昔布胶囊口服治疗(2次/d, 1粒/次,共治疗4周)。2组均按照VAS计分标准、WOMAC计分观察临床疗效。结果治疗组总有效率为90.6%,对照组总有效率为81.3%,差异具有统计学意义(P 0.05)。结论腕踝针配合推拿疗法和口服药物疗法,在治疗膝骨性关节炎方面均有疗效,但前者疗效更明显。     

推拿配合电针治疗膝骨性关节炎38例临床分析

目的:探讨推拿配合电针治疗膝骨性关节炎的临床疗效。方法:采用中医推拿手法配合电针治疗膝骨性关节炎38例,运用Lysholm膝关节功能评分表判定临床疗效。结果:本组患者38例,显效23例(60.5%),进步9例(占23.5%),有效3例(占8.0%),无效3例(占8.0%),总有效率达92.1%。结论:推拿配合电针治疗可理筋舒骨,恢复关节功能,减轻疼痛肿胀。操作简便,疗效显著,可在临床推广应用。     

中医推拿辅治退行性膝关节炎的80例临床疗效

目的:探讨中医推拿辅助治疗退行性膝关节炎的疗效,以供临床治疗此疾病参考使用。方法:将骨科门诊2011年1月收治的80例退行性膝关节炎的患者随机分为2组,2组患者的一般资料及疾病严重程度比较无明显差异。对照组患者40例,给予玻璃酸钠注射治疗;实验组患者40例,在对照组治疗方法的基础上辅助以中医推拿治疗,比较2组患者的治疗效果,并将结果进行统计学分析。结果:实验组患者80例,其总有效率为93.75%(75/80);对照组患者总有效率为78.75%(63/80),2组患者比较有显著差异,经SPSS18.0软件统计学分析,χ2=5.94,p<0.05,差异有统计学意义。结论:采用中医推拿辅助对退行性关节炎进行治疗可以取得较好的治疗效果,减少患者治疗费用,进而提高其生活质量,值得在临床工作中应用。     

电针配合推拿治疗面神经麻痹临床观察

目的观察电针配合推拿治疗周围性面神经麻痹的临床疗效。方法将90例周围性面神经麻痹患者随机分为电针配合推拿(治疗组)、电针组和推拿组(对照组)。结果治疗组总有效率为93.3%,优于对照组83.3%和80%(P<0.05)。结论电针配合推拿治疗周围性面神经麻痹疗效肯定。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.