干扰素局部注射联合激光治疗前尿道尖锐湿疣

目的观察尿道局部注射干扰素联合CO2激光治疗男性前尿道尖锐湿疣的疗效。方法CO2激光去除疣体、尿道局部注射干扰素治疗男性前尿道尖锐湿疣患者61例。结果经观察6～12个月，26例（42．6％）经1次激光治疗痊愈，22例（36．1％）经2次激光治疗痊愈。结论尿道局部注射干扰素联合CO2激光治疗男性前尿道尖锐湿疣简便、经济、疗效确切。     

利普刀术与干扰素局部注射联合治疗女性尖锐湿疣

目的 观察利普刀术与干扰素局部注射联合治疗女性尖锐湿疣的疗效.方法 利普刀术联合局部注射干扰素治疗女性尖锐湿疣患者56例.结果 经观察6～12个月,26例(46.4%)经一次利普刀术治疗痊愈,23例(41.1%)经二次利普刀术治疗痊愈,5例(8.9%)经3次利普刀术治愈,2例(3.6%)经4～6次利普刀术治愈.结论 利普刀术与干扰素局部注射联合治疗女性尖锐湿疣简便、经济、疗效确切.     

CO2激光联合重组干扰素α-2b凝胶治疗男性尿道口尖锐湿疣21例

目的观察CO2激光联合重组干扰素α-2b凝胶治疗男性尿道口尖锐湿疣的疗效。方法21例男性尿道口尖锐湿疣的患者，采用LJL35-CB型CO2激光治疗机激光治疗后，再涂抹重组干扰素α-2b凝胶，一134次，连续用药6周为1疗程。结果治疗后每2周复诊一次，连续随访3个月，其中一次性痊愈16例；复发后重复经上述治疗1次后痊愈5例。结论CO2激光联合重组干扰素α-2b凝胶治疗男性尿道口尖锐湿疣，具有预防重复感染，减少复发，提高疗效等优点，值得临床推广应用。     

CO2激光联合干扰素γ局部注射治疗尖锐湿疣43例临床观察

目的　探讨免疫疗法联合二氧化碳 (CO2 )激光治疗尖锐湿疣的疗效和作用机理。方法　用CO2 激光联合干扰素γ局部注射治疗尖锐湿疣 4 3例 (治疗组 )并与 4 2例单用CO2 激光 (对照组 )相比较。结果　两组治愈率分别为90 .7% ,38.1% ,治疗组明显高于对照组 ,两组间比较有非常显著性意义 (χ2 =2 3.4 9,P <0 .0 1)。结论　CO2 激光联合干扰素局部用药治疗尖锐湿疣能提高治愈率 ,有效降低复发     

氟尿嘧啶局部注射联合中药熏洗防治尖锐湿疣50例疗效观察

目的：探讨尖锐湿疣的有效治疗方法。方法：82例患者随机分为观察组50例,给予CO2激光、氟尿嘧啶局部注射及中药熏洗;对照组32例,给予CO2激光治疗。结果：观察组痊愈率92%,复发率8%;对照组痊愈率56.3%,复发率43.8%。结论：氟尿嘧啶局部注射联合中药熏洗治疗尖锐湿疣疗效满意。     

CO_2激光联合白细胞介素-2局部注射治疗尖锐湿疣疗效观察

目的:探讨CO2激光联合白细胞介素-2局部注射治疗尖锐湿疣的临床疗效。方法:将96例尖锐湿疣患者随机分为治疗组50例,对照组46例。两组病例均用CO2激光去除可见疣体。治疗组治疗后隔日1次局部注射白细胞介素-2,10～15次为一个疗程;对照组在激光治疗后,不再用任何其他治疗,疗程结束后观察疗效、复发情况。结果:治疗组痊愈44例,复发6例,痊愈率为88.0%,复发率为12.0%;对照组痊愈27例,复发19例,痊愈率为58.7%,复发率为41.3%。结论:白细胞介素-2具有免疫调节和抗病毒作用,CO2激光联合白细胞介素-2局部注射治疗尖锐湿疣有较好的临床疗效,可明显降低治疗后复发率。     

a-2b干扰素栓联合CO_2激光治疗女性宫颈尖锐湿疣临床疗效评价

目的评价a-2b干扰素栓联合CO2激光治疗女性宫颈尖锐湿疣的疗效。方法将81例女性宫颈尖锐湿疣患者随机分为两组,对照组38例常规使用CO2激光治疗祛除皮损;治疗组43例在使用CO2激光治疗基础上加用a-2b干扰素栓阴道深部给药。结果治疗组痊愈40例（93.03%）,复发3例（6.97%）;对照组痊愈22例（57.90%）,复发16例（42.10%）;两组复发率比较,差异有显著性（2χ=9.44,P〈0.01）。结论 a-2b干扰素栓局部用药,能提高局部细胞免疫水平和女性宫颈尖锐湿疣的治愈率,明显降低复发率。     

激光联合干扰素治疗女性尖锐湿疣临床观察

目的 :观察激光联合干扰素局部注射治疗女性尖锐湿疣的临床疗效。方法 :在激光祛除肉眼可见病灶后 ,治疗组用干扰素局部注射治疗尖锐湿疣 6 3例 ,同时与单纯激光治疗的 5 9例作对照。结果 :治疗组痊愈率为 88. 9% ,复发率为 10 . 7% ;对照组痊愈率为 4 5 8% ,复发率为 5 1 .8% ,两组比较有显著性差异(P <0 . 0 1)。结论 :激光联合干扰素在治疗女性尖锐湿疣方面疗效显著。     

重组人干扰素联合激光治疗外阴尖锐湿疣的疗效观察

目的:评价重组人干扰素α-2b联合激光治疗尖锐湿疣的疗效及安全性。方法:对2003年7月~2004年7月发病的120例外阴尖锐湿疣患者,随机分治疗组80例,对照组40例,观察时间8周。结果:重组人干扰素α-2b联合激光治疗外阴尖锐湿疣痊愈率85.0%、有效率11.2%,明显优于对照组痊愈率40.0%,有效率45%(P<0.01)。结论:重组人干扰素α-2b联合激光治疗外阴尖锐湿疣有非常好的临床效果且十分安全。     

CO_2激光联合甘露聚糖肽治疗尖锐湿疣疗效观察

目的:观察CO2激光联合甘露糖肽治疗尖锐湿疣的疗效。方法:采用随机分组法,将60例患者分为两组,治疗组30例,经CO2激光治疗后,甘露聚糖肽注射液5 mg,肌内注射,2次/d,连用7 d后,改为1次/d,再连用21 d;对照组30例,单纯CO2激光治疗。随访半年,无复发为痊愈,复发为未痊愈。结果:两组治愈率、复发率经统计学比较,差异有统计学意义(P<0.05),治疗组疗效优于对照组。结论:CO2激光联合甘露聚糖肽治疗尖锐湿疣有疗效好、不良反应小等特点,值得推广。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.