Warm needling moxibustion plus functional exercises for knee osteoarthritis

Objective

To observe the clinical efficacy of warm needling moxibustion plus functional exercises in treating knee osteoarthritis (KOA).

Methods

Totally 108 eligible KOA patients were intervened by warm needling moxibustion plus functional exercises. The warm needling moxibustion was given 3 times a week, successively for 4 weeks. The visual analogue scale (VAS) was adopted to evaluate the pain intensity of the knee joint. After 4-week treatment, the change of VAS score, range of motion (ROM) of knee, and Lysholm score were observed, and the clinical efficacy was also estimated.

Results

After treatment, the VAS score dropped obviously, and the ROM and Lysholm score increased markedly; the total effective rate was 83.3%.

Conclusion

Warm needling moxibustion plus functional exercises is effective in treating KOA, as it can relieve the knee joint pain and improve the joint motion.

     

针刀治疗腕管综合征的病例对照研究

目的:研究针刀治疗腕管综合征的疗效。方法:2014年7月至2016年12月,60例门诊收治的腕管综合征患者分为两组,针刀治疗组(治疗组)和支具药物组(对照组),每组30例。治疗组男8例,女22例;平均年龄(49.38±7.43)岁。对照组男7例,女23例;平均年龄(50.23±8.71)岁。治疗前两组患者的年龄、性别、病程、感觉神经传导速度(SCV)、感觉神经动作电位波幅(SNAP)、运动传导末端潜伏期(DML)差异无统计学意义。治疗组患者采用针刀治疗1~2次;对照组患者口服塞来昔布、维生素B1、维生素B12,并采用支具固定;疗程结束后观察两组患者SCV、SNAP、DML变化。结果:两组患者治疗后,SCV分别为(48.63±7.33)、(41.24±6.15)m/s,SNAP分别为(9.89±3.71)、(8.22±2.19)m/s,DML分别为(5.11±2.28)、(6.13±2.23)m/s,均较治疗前改善,且治疗组优于对照组。结论:针刀疗法可以减轻患者症状,具有可行性,适合在临床中推广使用。     

艾灸通过调控NLRP3炎性小体缓解5-氟尿嘧啶诱导的大鼠化疗性肠黏膜炎的实验研究

目的:探讨艾灸通过调控核苷酸结合寡聚化结构域样受体3(NLRP3)缓解5-氟尿嘧啶(5-FU)诱导的化疗性肠黏膜炎的作用机制。方法:将30只SD大鼠随机分为正常组、模型组和艾灸组,每组10只,造模前7 d对艾灸组行艾灸处理,模型组与艾灸组采用单次腹腔注射5-FU造模,造模完成后,艾灸组继续行艾灸处理,正常组与模型组常规饲养,观察各组大鼠一般情况,检测血清中IL-1β、TNF-α、NLRP3含量,观察结肠组织病理改变,检测结肠组织NLRP3 mRNA表达水平,以及NLRP3组成相关蛋白及IL-1β的表达。结果:腹腔注射5-FU后,模型组体质量和摄食量下降明显,肠黏膜形态不规则,损伤严重,肠绒毛变短融合,上皮细胞排列紊乱。与模型组比较,艾灸组体质量增长、血便、摄食量均有不同程度改善,疾病活动指数评分显著低于模型组。艾灸组血清中IL-1β、TNF-α、NLRP3含量均显著低于模型组(P0.05或P0.01);艾灸组结肠组织中NLRP3炎性小体组成部分NLRP3、Caspase-1、ASC蛋白及IL-1β表达显著低于模型组(P0.05)。结论:艾灸可通过抑制NLRP3炎性小体改善5-FU诱导的大鼠化疗性肠黏膜炎症状。     

针药并用治疗视神经萎缩疗效观察

目的观察针药并用治疗视神经萎缩的临床疗效。方法 64例视神经萎缩患者88只眼,随机分为治疗组(33例46只眼)和药物组(31例42只眼)。药物组予以口服复方银杏胶囊、甲钴胺治疗,治疗组在药物组治疗的基础上联合针刺治疗。观察两组治疗前后视野MD值和视觉诱发电位(P-VEP)值变化,并比较两组临床疗效。结果治疗组总有效率为87.0%,对照组为59.5%,两组比较差异有统计学意义(P0.05)。两组治疗后视野MD值和P-VEP值与治疗前比较,差异有统计学意义(P0.05)。两组治疗后视野MD值和P-VEP值比较,差异有统计学意义(P0.05)。结论针药并用可以改善视神经萎缩患者的视野和视觉诱发电位,效果显著。     

绝骨穴的文献研究探微

绝骨穴又名悬钟、髓会,是足少阳胆经的第39个穴位,为八会穴之髓会。本文分析整理绝骨穴在古代文献中的记载,明晰该穴位的穴名渊源、定位及循经、穴性特点、主治应用规律以及刺法灸法和禁忌。总结可知绝骨穴具有疏肝利胆、舒筋活络、补肾壮骨、益髓健脑的功效,古代和现代多运用该穴治疗内、外、妇、儿、五官科多种疾病,临床应用范围十分广泛。整理和分析古代文献中的相关记载对于拓宽绝骨穴的临床运用思路大有益处,为临床应用和穴位实质的科学研究提供更多的参考依据。     

经络的生物学实质研究进展

基于近年分子生物学、生物化学、生物信息学等交叉学科的发展,许多相关学科的学者从生物学的不同角度来探讨经络的实质问题,由原本可见的生理生化的客观观察和实验性研究发展到信息载体及信息产生的形式及过程以及信息功能,并向一种不可见的对应性"结构"     

Acupuncture for dry eye syndrome: a meta-analysis of randomized controlled trials

Objective

To summarize and critically assess the evidence from randomized controlled trials (RCTs) of acupuncture in treating dry eye syndrome (DES) according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and the Cochrane Collaboration recommendations.

Methods

A search of PubMed, the Cochrane Central Register of Controlled Trials, ClinicalTrials.gov and Embase was made from their inception to August 2016, as well as Chinese, Japanese, and Korean databases. Two reviewers independently selected RCTs and assessed the methodological quality. Meta-analysis and the level of evidence were processed by RevMan 5.3 and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.

Results

After selection, 8 trials were subjected to our systematic review. The methodological quality was low generally. The 3-10 weeks follow-up showed that acupuncture improved the tear film break-up time (BUT) (MD=1.33, 95% CI=1.01-1.66, 619 participants). The mean difference of Schirmer’s test was 1.73 mm (95%CI=1.28-2.18, 618 participants) between the acupuncture group and the control group. The subjective variables exhibited no significant differences.

Conclusion

The low methodological quality of the trials does not suggest drawing firm conclusions on the value of acupuncture therapy for DES. Acupuncture treatment may have some effects on the tear film BUT and Schirmer’s test, but not on the subjective symptoms. Well-planned large-scale high-quality RCTs are needed to make it clear whether acupuncture is effective in treating DES.

     

经络的实质：现代的思考

Meridian essence has been investigated through anatomy, electrophysiology, biophysics, and biochemistry. Various hypotheses of meridian essence exist, but no hypothesis can truly reflect the internal character of Chinese medicine (CM). The research of meridian essence requires a holistic viewpoint and innovative awareness. Initially, any hypothesis regarding meridian essence should begin with observation of the human body. Secondly, the research should arise from the meridians’ physical functions and pathological changes, so as to maintain the fundamental nature of the meridians themselves. Thirdly, the research should be based upon the theory of CM, yet coupled with the integration of modern techniques to deepen our understanding of the scientific contents of meridians. Fourthly, theoretical research should be combined closely with clinical practice, in order to test the achievements in actual conditions. Lastly, more attention should be given to negative results in studies to more accurately discover the real essence of meridians.     

鼻三针联合穴位贴敷治疗肺虚感寒型变应性鼻炎的临床研究

目的 采用多中心随机对照研究观察鼻三针联合穴位贴敷治疗肺虚感寒型变应性鼻炎的临床疗效.方法 将160例符合纳入标准的肺虚感寒型变应性鼻炎患者随机分为两组(治疗组79例,对照组81例).治疗组用鼻三针联合穴位贴敷进行治疗,对照组采用安慰治疗.比较两组患者治疗前、治疗2周后、治疗后、治疗后4周、治疗后8周以及治疗后12周的...     

针灸治疗顽固性面瘫的临床研究进展

对近年来针灸治疗顽固性面瘫的临床研究进展进行综述。分别从顽固性面瘫的病因病机、常用的治疗方法以及针灸治疗顽固性面瘫穴位的选择进行整理和分析,并尝试探讨目前临床治疗中的问题以及提出更好地解决方法。为今后的科研和临床提供参考依据。