全文获取类型
收费全文 | 124623篇 |
免费 | 9255篇 |
国内免费 | 944篇 |
专业分类
耳鼻咽喉 | 1828篇 |
儿科学 | 2755篇 |
妇产科学 | 2055篇 |
基础医学 | 16448篇 |
口腔科学 | 2779篇 |
临床医学 | 11803篇 |
内科学 | 27322篇 |
皮肤病学 | 2454篇 |
神经病学 | 11184篇 |
特种医学 | 5473篇 |
外国民族医学 | 1篇 |
外科学 | 20119篇 |
综合类 | 1287篇 |
一般理论 | 208篇 |
预防医学 | 7530篇 |
眼科学 | 2707篇 |
药学 | 8509篇 |
中国医学 | 473篇 |
肿瘤学 | 9887篇 |
出版年
2023年 | 938篇 |
2022年 | 681篇 |
2021年 | 3738篇 |
2020年 | 2308篇 |
2019年 | 3613篇 |
2018年 | 4249篇 |
2017年 | 3019篇 |
2016年 | 3436篇 |
2015年 | 4074篇 |
2014年 | 5378篇 |
2013年 | 6706篇 |
2012年 | 10041篇 |
2011年 | 10233篇 |
2010年 | 5771篇 |
2009年 | 4992篇 |
2008年 | 8189篇 |
2007年 | 7882篇 |
2006年 | 7519篇 |
2005年 | 7364篇 |
2004年 | 6546篇 |
2003年 | 6067篇 |
2002年 | 5432篇 |
2001年 | 1353篇 |
2000年 | 1126篇 |
1999年 | 1230篇 |
1998年 | 950篇 |
1997年 | 773篇 |
1996年 | 613篇 |
1995年 | 709篇 |
1994年 | 576篇 |
1993年 | 532篇 |
1992年 | 660篇 |
1991年 | 554篇 |
1990年 | 556篇 |
1989年 | 535篇 |
1988年 | 524篇 |
1987年 | 460篇 |
1986年 | 461篇 |
1985年 | 447篇 |
1984年 | 488篇 |
1983年 | 411篇 |
1982年 | 404篇 |
1981年 | 393篇 |
1980年 | 322篇 |
1979年 | 260篇 |
1978年 | 268篇 |
1977年 | 234篇 |
1976年 | 170篇 |
1975年 | 191篇 |
1974年 | 182篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
Espersen Caroline Modin Daniel Hoffmann Søren Hagemann Christoffer A. Hagemann Rikke A. Olsen Flemming J. Fritz-Hansen Thomas Platz Elke Møgelvang Rasmus Biering-Sørensen Tor 《The international journal of cardiovascular imaging》2022,38(1):131-140
The International Journal of Cardiovascular Imaging - Global longitudinal strain (GLS) has proven to be a powerful prognostic marker in various patient populations, but the prognostic value of... 相似文献
3.
Kevin Kyung Ho Choi Santosh Sanagapalli 《World journal of gastrointestinal oncology》2022,14(3):568-586
Barrett's esophagus (BE) is the precursor to esophageal adenocarcinoma (EAC). Progression to cancer typically occurs in a stepwise fashion through worsening dysplasia and ultimately, invasive neoplasia. Established EAC with deep involvement of the esophageal wall and/or metastatic disease is invariably associated with poor long-term survival rates. This guides the rationale of surveillance of Barrett’s in an attempt to treat lesions at an earlier, and potentially curative stage. The last two decades have seen a paradigm shift in management of Barrett’s with rapid expansion in the role of endoscopic eradication therapy (EET) for management of dysplastic and early neoplastic BE, and there have been substantial changes to international consensus guidelines for management of early BE based on evolving evidence. This review aims to assist the physician in the therapeutic decision-making process with patients by comprehensive review and summary of literature surrounding natural history of Barrett’s by histological stage, and the effectiveness of interventions in attenuating the risk posed by its natural history. Key findings were as follows. Non-dysplastic Barrett’s is associated with extremely low risk of progression, and interventions cannot be justified. The annual risk of cancer progression in low grade dysplasia is between 1%-3%; EET can be offered though evidence for its benefit remains confined to highly select settings. High-grade dysplasia progresses to cancer in 5%-10% per year; EET is similarly effective to and less morbid than surgery and should be routinely performed for this indication. Risk of nodal metastases in intramucosal cancer is 2%-4%, which is comparable to operative mortality rate, so EET is usually preferred. Submucosal cancer is associated with nodal metastases in 14%-41% hence surgery remains standard of care, except for select situations. 相似文献
4.
Jana Kristin Eckert Julia Kahle Andreas Bck Kathrin Zeber Kathrin Urner Wolfgang Greiner Simone Kreimeier Kirsten Beyer Josefine Dobbertin-Welsch Eckard Hamelmann Ines Gellhaus Christina Schorlemer Michael Kabesch Parastoo Kheiroddin Erika von Mutius Martin Depner Daniel Walter Gesine Hansen Stephanie DeStefano Sabine Schnadt Bianca Schaub 《Pediatric allergy and immunology》2022,33(1):e13652
5.
6.
7.
8.
Journal of Public Health - The first Covid-19 cases were reported in Malaysia on 25 January 2019 followed by a quiescent period before an upward swing of the cases at the end of February 2020,... 相似文献
9.
Michels Guido Horn Rudolf Helfen Andreas Hagendorff Andreas Jung Christian Hoffmann Beatrice Jaspers Natalie Kinkel Horst Greim Clemens-Alexander Knebel Fabian Bauersachs Johann Busch Hans-Jörg Kiefl Daniel Spiel Alexander O. Marx Gernot Dietrich Christoph F. 《Der Anaesthesist》2022,71(4):307-310
Die Anaesthesiologie - 相似文献
10.
Cody M. Lebeck Lee MD Ioannis A. Ziogas MD Rajiv Agarwal MD Sophoclis P. Alexopoulos MD Kristen K. Ciombor MD Lea K. Matsuoka MD Daniel B. Brown MD Cathy Eng MD 《Cancer》2022,128(12):2243-2257
The 5-year overall survival rate of a patient with unresectable metastatic colorectal cancer is poor at approximately 14%. Similarly, historical data on liver transplantation (LT) in those with colorectal liver metastases (CRLM) showed poor outcomes, with 5-year survival rates between 12% and 21%. More recently, limited data have shown improved outcomes in select patients with 5-year overall survival rates of approximately 60%. Despite these reported survival improvements, there is no significant improvement in disease-free survival. Given the uncertain benefit with this therapeutic approach and a renewed investigational interest, we aimed to conduct a contemporary systematic review on LT for CRLM. A systematic review of the literature was performed according to the preferred reporting items for systematic reviews and meta-analysis statement. English articles reporting on data regarding LT for CRLM were identified through the MEDLINE (via PubMed), Cochrane Library, and ClinicalTrials.gov databases (last search date: December 16th, 2021) by 2 researchers independently. A total of 58 studies (45 published and 13 ongoing) were included. Although early retrospective studies suggest the possibility that some carefully selected patients may benefit from LT, there is minimal prospective data on the topic and LT remains exploratory in the setting of CRLM. Additionally, several other challenges, such as the limited availability of deceased donor organs and defining appropriate selection criteria, remain when considering the implementation of LT for these patients. Further evidence from ongoing prospective trials is needed to determine if and to what extent there is a role for LT in patients with surgically unresectable CRLM. 相似文献