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排序方式: 共有100条查询结果,搜索用时 15 毫秒
1.
目的 探索虚拟现实技术应用于口腔实训教学中的实践效果。方法 选择上海交通大学口腔医学院72名学生,随机分为实验组和对照组,每组36名,实验组采用将虚拟现实技术应用于口腔实训教学,对照组采用传统教学方法,课程结束后,比较2组学生的操作技能成绩和理论成绩,问卷调查评估实验组学生对虚拟现实技术应用于教学的评价。结果 实验组学生的操作技能和掌握知识要点显著优于对照组,虚拟现实技术应用在口腔实训中,学生学习能力明显提高。结论 虚拟现实技术运用于口腔实训教学中能加深学生的认知程度,从而提升教学质量,加快教育教学方式朝高度现代化发展。 相似文献
2.
为了提高儿童口腔教学的质量,引入了以问题为基础的教学法(Problem-based learning,PBL), 对上海交通大学口腔医学院08 级和09 级口腔专业本科阶段学生开展儿童口腔科学PBL 教学,采用问卷的方法进行结果评价。PBL 教学在一定程度上提高了学生的自主性和综合思考能力, 可以在儿童口腔教学中推广应用。 相似文献
3.
目的 探讨首发抑郁症患者的细胞因子水平变化及度洛西汀对其的影响.方法 采用酶联免疫吸附法(ELISA)检测38例抑郁症患者度洛西汀治疗前、后血清白细胞介素-1(IL-1)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、白细胞介素-4(IL-4)、白细胞介素-10(IL-10)水平;于治疗前后进行汉密顿抑郁量表评分,进行疗效评估,并与30例健康体检者进行比较,进行统计分析.结果 治疗前,首发抑郁症患者血清IL-6、TNF-α、IL-1浓度[(10.66±3.12) pg/ml,(77.49±3.12) pg/ml,(39.09±3.77) pg/ml]均显著高于正常对照组[(2.72±0.91)pg/ml,(37.48±5.87) pg/ml,(10.31±1.05) pg/ml];血清IL-4、IL-10浓度[(3.18±0.46) pg/ml,( 102.66±20.50) pg/ml]明显低于正常对照组[(7.85±0.49) pg/ml,(181.00±33.85) pg/ml];经度洛西汀治疗后,患者血清IL-6、TNF-α、IL-1浓度明显较治疗前有显著下降(P<0.05),血清IL-4、IL-10浓度较治疗前显著升高(P<0.05),但血清IL-6、TNF-α、IL-1浓度仍明显高于正常对照组(P<0.05).相关性分析表明,血清IL-6、TNF-α、IL-1水平与HAMD总分呈明显正相关(r分别为0.667,0.486,0.727,P<0.01),而血清IL-4、IL-10水平则与HAMD总分呈明显负相关(r分别为-0.433,-0.269,P<0.05,P<0.01).结论 首发抑郁症患者存在细胞因子介导的免疫功能紊乱,度洛西汀可能通过调节细胞因子及Th1/Th2失衡发挥抗抑郁作用. 相似文献
4.
目的 探讨单相抑郁症、双相抑郁症患者血管紧张素转化酶(ACE)基因第16内含子中287bp插入/缺失(I/D)多态的分布,以及ACE基因多态与抑郁症的关联性.方法 以100例抑郁症患者和100例正常对照组为对象进行病例对照研究,采用PCR检测ACE基因I/D多态性.结果 该多态位点的基因型在抑郁症组和正常对照组之间总体分布差异无显著性(P>0.05),两组间等位基因差异无显著性(P>0.05).结论 ACE基因I/D多态性与抑郁症不存在关联. 相似文献
5.
目的评价DiaSys FE-2粪便分析工作站的临床应用价值。方法对503份粪便标本用直接涂片镜检法、加藤氏玻璃纸厚层涂片法、FE-2工作站法进行肠道寄生虫检查。结果 FE-2工作站法较直接涂片法虫卵检出率提高5.55倍,较加藤氏玻璃纸厚层涂片法虫卵检出率提高4.87倍;对蛔虫卵检出率提高10倍、鞭虫卵、钩虫卵检出率提高5倍,华支睾吸虫卵检出率提高4.5倍。结论 FE-2工作站设计新颖、标准定量、准确可靠。操作简便、卫生环保,能有效提高肠道寄生虫检出率,是一台适用于肠道寄生虫病防治的实用性仪器,值得推广使用。 相似文献
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7.
Objective To evaluate the association of 2616c/T polymorphism in iron regulatory protein 2(IRP2)gene with Alzheimer disease(AD)and Vascular dementia(VD).Methods In this study,281 patients with AD,60 with VD,and 285 normal aged were recruited.The 2616C/T polymorphism in IRP2 gene was analyzed by using polymerase chain reaction-restriction fragment length polymorphism.And the cognitive function was assessed with the Mini-Mental State Examination(MMSE).Results (1)No significant difieFences were demonstrated in IRP2 genotype or allele frequencies between AD patients and controls(χ2=2.46,P=0.292;χ2=2.17,P=0.141 respectively).However,when AD patients were stratified by disease severity.the frequency of T allele carriers in the moderate to severe AD patients was 78.0%,significantly higher than that in controls(69.8%;χ2=4.106,P<0.05).Logistic regression analysis demonstrated that the age-,sex-and ApoE-adiusted OR of modcrate to severe AD patient with T allele was 1.62(95% CI=1.03-2.54).The frequency of T allele carriers or T allele in VD patients was higher than that of controls,but the difference was not statistically significant(P>0.05).(2)The frequency of tit genotype or T allele in the moderate to severe AD patients was significantly higher than that in mild AD patients(25.8%vs.12.5%,χ2=5.477,P<0.05;51.9%vs.40.3%,χ2=5.803,P<0.05 respectively).(3)MMSE scores of the AD patients with TT genotype was significantly lower than ones with CC or CT genotype(P=0.028;P=0.014 respectively).Conclusion The 2616C/T polymorphism in the IRP2 gene is possibly associated with moderate to severe AD.but not associated with VD.And the TT genotype may be a risk factor for cognitive impairment of patients with AD in Chinese Han. 相似文献
8.
Objective To evaluate the association of 2616c/T polymorphism in iron regulatory protein 2(IRP2)gene with Alzheimer disease(AD)and Vascular dementia(VD).Methods In this study,281 patients with AD,60 with VD,and 285 normal aged were recruited.The 2616C/T polymorphism in IRP2 gene was analyzed by using polymerase chain reaction-restriction fragment length polymorphism.And the cognitive function was assessed with the Mini-Mental State Examination(MMSE).Results (1)No significant difieFences were demonstrated in IRP2 genotype or allele frequencies between AD patients and controls(χ2=2.46,P=0.292;χ2=2.17,P=0.141 respectively).However,when AD patients were stratified by disease severity.the frequency of T allele carriers in the moderate to severe AD patients was 78.0%,significantly higher than that in controls(69.8%;χ2=4.106,P<0.05).Logistic regression analysis demonstrated that the age-,sex-and ApoE-adiusted OR of modcrate to severe AD patient with T allele was 1.62(95% CI=1.03-2.54).The frequency of T allele carriers or T allele in VD patients was higher than that of controls,but the difference was not statistically significant(P>0.05).(2)The frequency of tit genotype or T allele in the moderate to severe AD patients was significantly higher than that in mild AD patients(25.8%vs.12.5%,χ2=5.477,P<0.05;51.9%vs.40.3%,χ2=5.803,P<0.05 respectively).(3)MMSE scores of the AD patients with TT genotype was significantly lower than ones with CC or CT genotype(P=0.028;P=0.014 respectively).Conclusion The 2616C/T polymorphism in the IRP2 gene is possibly associated with moderate to severe AD.but not associated with VD.And the TT genotype may be a risk factor for cognitive impairment of patients with AD in Chinese Han. 相似文献
9.
辨证治疗肾病综合征顽固性水肿60例临床观察 总被引:2,自引:1,他引:1
以温阳利水法为主治疗60例,浮肿消退占50%,部分消退占41.72%,无变化占8.3%;治疗前后24h尿蛋白定量、血浆白蛋白、总胆固醇无变化;血尿素氮较治疗前差别显著;前列腺素I2治疗后较治疗前提高,差别显著;血栓素A2治疗后较治疗前降低,差别显著。 相似文献
10.