华法林抗凝治疗非瓣膜性房颤的临床研究

房颤抗凝治疗的必要性越来越受到重视,以国际标准化比(international normalized ratio,INR)评价华法林钠(商品名:华法林)的抗凝强度亦得到公认[1,2].由于地域和种族的差别,适合我国的INR最佳标准还未确定,我院对101例房颤患者进行INR监测以指导调整华法林剂量,收到良好效果,现对资料完整、持续用药大于3个月共89例进行分析总结如下.     

足月新生儿出生体重与母婴脂联素水平的相关性研究

Objective To study the characteristics of plasma adiponectin levels exhibiting in gestation women and newborns, as well as the relationships between adiponectin levels and fetal birth weight. Methods Totally 98 subjects have been considered in this study, in-cluding venous blood samples of 36 healthy non-pregnant women (control group), 31 uncomplicated pregnant women (pregnancies group) and the cord blood samples taken at delivery of their singleton infants born at term (newborns group). The concentrations of adiponectin and insulin were determined by radioimmunoassay technique. And SPSS was used for statistical analyses. Results The adiponectin level in women of late period of gestation (WLPG) (11.10±5.72)g/ml was lower than that of other two groups, and the newborns average cord plasma level of adiponectin was (30.71±12.77) g/ml significantly higher than that of the control group (16.52±6.87) g/ml. The adipone-ctin level for WLPG was correlated with FINS and HOMA-IR (r = -0.411, -0.393, P <0.05). The adiponectin level in cord plasma was positively correlated with birth weight(r = 0.416, P < 0.05). The adiponectin level in WLPG was correlated neither with the adiponec-tin level nor body weights of their newborns. Conclusions The average cord plasma adiponectin level of newboms is significantly higher than that of the control group and WLPG. It is positively correlated with birth weight, which suggests that adiponectin may be involved in reg-ulating fetal growth. The adiponectin level in WLPG is correlated neither with the adiponectin level nor body weights of their newborns.     

婴儿肝间叶性错构瘤1例

患儿女,1岁,住院号:355316。以发现右腹部肿物2月就诊。体查:腹膨隆,右上腹可触及一巨大肿块,与肝脏相连,下缘与脐平,质硬,表面可触及小结节,无活动,无压痛,脾未触及。B超提示:肝右叶占位性病变。以肝脏肿瘤行手术。术中见:肝脏增大至肋缘下约10cm,肿物位于肝右前叶,大小10×10×10cm,表面有一薄层组织覆盖,质硬。肝左叶正常,肝门未浸及,行肿物单纯切除术。肉眼检查:灰白灰红色椭圆形肿物一个,大小12     

三联疗法治疗乙型肝炎病毒携带者的临床观察

我们自 2 0 0 2年以来 ,应用左旋咪唑涂布剂联合潘生丁、乙肝疫苗 (以下简称三联疗法 )治疗慢性乙型肝炎病毒携带者 ,取得了较好的疗效。现总结如下。1　资料和方法1.1　病历选择按照 1995年全国病毒性肝炎会议诊断标准选择。从 2 0 0 0年 6月～ 2 0 0 2年 4月在我院门诊和住院患者中慢性乙型肝炎病毒携带者中HBs’Ag、HBeAg、HBV -DNA阳性 ,且持续 6mon以上 ,肝功能正常者为治疗观察对象。所有病例均非母婴传播者。随机分为 2组 ,其中治疗组 96例 :男 83例 ,女 14例 ,年龄最大者 6 3岁 ,最小者 12岁 ,平均 38 5岁。对照组 90例 ,其中…     

足月新生儿出生体重与母婴脂联素水平的相关性研究

目的探讨足月孕妇和新生儿脐静脉血中脂联素（Adiponectin）水平特点及其与新生儿体重的关系。方法采用放射免疫法测定36例健康育龄期妇女（对照组）和31例正常足月孕妇（妊娠组）及其新生儿脐静脉血（新生儿组）的血清胰岛素及脂联素水平,并进行统计学分析。结果足月孕妇血清脂联素水平最低（11．10±5．72）g／ml;新生儿脐血脂联素水平为（30．71±12．77）g/ml,妊娠组高于对照组妇女（16．52±6．87）g/ml;妊娠组脂联素水平与FINS、HOMA—IR呈负相关（r=-0．411、-0．393,P〈0．05）;新生儿脐血脂联素水平与新生儿出生体重正相关（r=0．416,P〈0．05）;母亲血清脂联素水平与新生儿脐血脂联素及出生体重无相关性。结论（1）新生儿组脂联素水平显著高于对照组及妊娠组;（2）新生儿脐血脂联素水平与其出生体重正相关,表明新生儿脂联素可能与胎儿宫内发育有关;（3）足月孕妇脂联素水平与新生儿脂联素水平、出生体重无相关性。