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目的评价吾真宁、可乐必妥、阿奇霉素(泰力特)3种治疗慢性前列腺炎药物经济学效果。方法对75例慢性前列腺炎病人分别应用吾真宁、可乐必妥、泰力特治疗,运用药物经济学的成本-效果分析方法进行评估。结果无论是症状消失还是体征消失的效果,吾真宁组的成本效果比均低于可乐必妥及泰力特组。结论吾真宁为慢性前列腺炎患者提供了一种有效、安全、经济的口服药物。 相似文献
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目的 以实时荧光定量PCR技术测定前列腺增生(BPH)与前列腺癌(PCa)组织标本KLK11/TMPRSS mRNA比值,探讨KLK11/TMPRSS比值在前列腺癌诊断的特异性意义.方法 通过实时荧光定量PCR对23例PCa、37例BPH及3例正常前列腺组织KLK11/TMPRSS的表达,比较其在PCa与BPH中组织定量的差异.结果 BPH与PCa组织KLK11/TMPRSS mRNA的定量表达值分别为2.264±0.460与5.905±0.780,差异有统计学意义(P<0.05).结论 实时荧光RTPCR定量检测KLK11/TMPRSS mRNA为前列腺癌的诊断提供了可靠的辅助指标. 相似文献
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逆行输尿管镜手术并发症(附2316例报告) 总被引:1,自引:0,他引:1
目的 总结分析逆行输尿管镜手术并发症的发生原因及防治措施.方法 对本院2004年10月-2010年10月2316例病人2468次逆行输尿管镜手术的临床资料进行回顾性分析.结果 总的并发症发生率7.1%(165/2316),操作失败78例(3.4%);结石移位至肾盂26例(1.1%);输尿管损伤30例(1.3%),其中膀胱壁内段穿孔形成输尿管黏膜下隧道9例(0.4%)、全层穿孔14例(0.6%)、部分断裂4例(0.2%)、黏膜撕脱3例(0.1%);输尿管内双J管移位10例(0.4%);16例(0.7%)出现早期术后并发症,包括严重感染5例(0.2%),持续较严重的血尿6例(0.3%),较严重的肾绞痛5例(0.2%);5例(0.2%)出现远期并发症,包括输尿管狭窄3例、持续存在膀胱输尿管返流2例.大部分的手术并发症(124例,75.2%)发生在操作者使用输尿管镜的最初2年中.结论 严格掌握手术适应证,提高术中操作技巧,采用正确的对应措施,能有效地减少并发症.Abstract: Objectives To summarize the complications of retrograde rigid ureteroscopy as well as their management. Methods A total of 2316 patients accepting retrograde rigid ureteroscopy from Oct 2006 to Oct 2010 were evaluated retropspectively. Results The rate of complications was 7. 1% (165/2316). The complications consisted of the ureteroscopy failure (78 cases, 3.4% ), migration of calcali (26 cases, 1. 1% ), ureteral injury (mucosal false passage [9 cases, 0.4% ], ureteral perforation [ 14 cases, 0.6% ], ureteral part fracture [4 cases,0. 2% ], ureteral avulsion [ 3 cases, 0. 1% ] ), migrated double-J stent ( 10 cases, 0. 4% ). Farly complications were described in 0.7% ( 16 cases): sepsis (5 cases, 0.2% ), serious persistent hematuria (6 cases, 0.3% ), serious renal colic ( 5 cases, 0.2% ). Late complications were ureteral stenosis ( 3 cases, 0. 1% ) and persistent vesicoureteral reflux (2 cases, 0. 1% ). Most (75.2%) of the complications occurred in the first 2 years of that operators used the ureteroscopy. Conclusions Strictly mastering surgical indications, strengthening preoperative training and mastering the surgical technique, taking correct measure is the key to reduce the failure rate and complications of ureteroscopy. 相似文献
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