全文获取类型
收费全文 | 7341篇 |
免费 | 519篇 |
国内免费 | 70篇 |
专业分类
耳鼻咽喉 | 69篇 |
儿科学 | 117篇 |
妇产科学 | 65篇 |
基础医学 | 323篇 |
口腔科学 | 103篇 |
临床医学 | 1082篇 |
内科学 | 707篇 |
皮肤病学 | 42篇 |
神经病学 | 239篇 |
特种医学 | 366篇 |
外科学 | 388篇 |
综合类 | 1154篇 |
预防医学 | 2262篇 |
眼科学 | 46篇 |
药学 | 619篇 |
2篇 | |
中国医学 | 231篇 |
肿瘤学 | 115篇 |
出版年
2024年 | 3篇 |
2023年 | 118篇 |
2022年 | 220篇 |
2021年 | 297篇 |
2020年 | 265篇 |
2019年 | 263篇 |
2018年 | 282篇 |
2017年 | 247篇 |
2016年 | 200篇 |
2015年 | 207篇 |
2014年 | 569篇 |
2013年 | 528篇 |
2012年 | 498篇 |
2011年 | 624篇 |
2010年 | 522篇 |
2009年 | 414篇 |
2008年 | 440篇 |
2007年 | 376篇 |
2006年 | 331篇 |
2005年 | 280篇 |
2004年 | 208篇 |
2003年 | 185篇 |
2002年 | 141篇 |
2001年 | 127篇 |
2000年 | 79篇 |
1999年 | 81篇 |
1998年 | 63篇 |
1997年 | 40篇 |
1996年 | 37篇 |
1995年 | 34篇 |
1994年 | 18篇 |
1993年 | 17篇 |
1992年 | 13篇 |
1991年 | 19篇 |
1990年 | 11篇 |
1989年 | 11篇 |
1988年 | 6篇 |
1987年 | 4篇 |
1985年 | 16篇 |
1984年 | 15篇 |
1983年 | 13篇 |
1982年 | 11篇 |
1981年 | 8篇 |
1980年 | 12篇 |
1979年 | 22篇 |
1978年 | 17篇 |
1977年 | 17篇 |
1976年 | 7篇 |
1975年 | 8篇 |
1973年 | 2篇 |
排序方式: 共有7930条查询结果,搜索用时 15 毫秒
41.
Tatiana Elghossain Sarah Bott Chaza Akik Hala Ghattas Carla Makhlouf Obermeyer 《The Journal of adolescent health》2019,64(1):8-19
Purpose
This article presents a systematic review of the prevalence of violence against adolescents in the 22 countries of the Arab League.Methods
Data on physical and emotional child maltreatment, sexual abuse, bullying and fighting, violence in schools, and intimate partner violence against adolescent girls were retrieved using: (1) a systematic search for peer-reviewed journal articles using Medline and the Social Sciences Citation Index; and (2) a search for nationally-representative, population-based surveys.Results
Published evidence suggests that physical, sexual, and emotional violence against adolescents is widespread in the Arab region. In many studies, prevalence rates exceeded other regional or global estimates, including rates of violent discipline, fighting, and intimate partner violence against adolescent girls. Data on certain forms of violence (e.g. violent discipline) are available from many Arab countries; but data on other forms, e.g., sexual abuse, are scarce. Most peer-reviewed journal articles are based on small studies with diverse operational definitions and methods, making comparisons challenging.Conclusions
High rates of violence against adolescents in the region merit greater attention from policy makers concerned with determinants of adolescent health. There is also a need to expand and improve the quality of quantitative and qualitative research on violence against adolescents in the region. 相似文献42.
《Health & place》2019
We examined if the assessment of the health impact of a national Dutch regeneration programme depends on using either a repeated cross-sectional or longitudinal study design. This is important as only the latter design can incorporate migration patterns. For both designs, we compared trends in medication use between target and control districts. We found differences in medication use trends to be modest under the longitudinal design, and not demonstrable under the repeated cross-sectional design. The observed differences were hardly influenced by migration patterns. We conclude that in the Netherlands migration patterns had little effect on the health impact assessment of this national urban regeneration programme, so either the cross-sectional or longitudinal evaluation study design will do. 相似文献
43.
《Journal of the American Dental Association (1939)》2021,152(10):842-854.e1
BackgroundResults from several randomized controlled trials have shown a beneficial effect of ozone in reducing postsurgical complications after impacted mandibular third-molar surgery, but the literature is lacking a systematic review and meta-analysis.MethodsThe authors conducted this systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines after exclusion and inclusion criteria were applied and the following outcome parameters were evaluated: pain, swelling, trismus, quality of life, number of analgesics consumed, and adverse events. RevMan Cochrane Collaboration software, Version 5.3, was used to perform meta-analysis and the Grading of Recommendation Assessment, Development and Evaluation approach was used to rate the certainty of evidence.ResultsPatients who underwent adjuvant ozone application reported lower pain scores than patients in the control group at 24 hours after surgery (95% CI, –3.94 to –1.56) and at 7 days (95% CI, –1.67 to –0.78). Pooled analysis of all 4 included trials revealed a standardized mean difference (SMD) in swelling of –0.44 at 24 hours, 0.63 at 72 hours, and –0.87 at 7 days after surgery in the experimental group. Higher mean estimates in mouth opening were experienced by patients who received ozone at 24 hours (SMD, 2.74; 95% CI, –1.93 to 7.41; 4 studies, 133 patients), 72 hours (SMD, 2.77; 95% CI, –0.63 to 6.17; 4 studies, 133 patients), and 7 days after surgery (SMD, 1.42 SMD; 95% CI, –1.34 to 4.18; 4 studies, 133 patients).Practical ImplicationsEvidence suggests that adjuvant ozone application can offer some benefit for reducing pain, improving quality of life, and decreasing mean intake of analgesics after impacted mandibular third-molar surgery, but it is not effective in reducing facial swelling and trismus, which paves the way for future research. 相似文献
44.
Ximena Gonzalo Agnieszka Broda Francis Drobniewski Gerald Larrouy-Maumus 《Clinical microbiology and infection》2021,27(6):912.e1-912.e5
ObjectivesBacterial diagnosis of mycobacteria is often challenging because of the variability of the sensitivity and specificity of the assay used, and it can be expensive to perform accurately. Although matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) has become the workhorse of clinical laboratories, the current MALDI methodology (which is based on cytosolic protein profiling) for mycobacteria is still challenging due to the number of steps involved (up to seven) and potential biosafety concerns. Knowing that mycobacteria produce surface-exposed species-specific lipids, we here hypothesized that the detection of those molecules could offer a rapid, reproducible and robust method for mycobacterial identification.MethodsWe evaluated the performance of an alternative methodology based on characterized species-specific lipid profiling of intact bacteria, without any sample preparation, by MALDI MS; it uses MALDI-time-of-flight (ToF) MS combined with a specific matrix (super-2,5-dihydroxybenzoic acid solubilized in an apolar solvent system) to analyse lipids of intact heat-inactivated mycobacteria. Cultured mycobacteria are heat-inactivated and loaded directly onto the MALDI target followed by addition of the matrix. Acquisition of the data is done in both positive and negative ion modes. Blinded studies were performed using 273 mycobacterial strains comprising both the Mycobacterium tuberculosis (Mtb) complex and non-tuberculous mycobacteria (NTMs) subcultured in Middlebrook 7H9 media supplemented with 10% OADC (oleic acid/dextrose/catalase) growth supplement and incubated for up to 2 weeks at 37°C.ResultsThe method we have developed is fast (<10 mins) and highly sensitive (<1000 bacteria required); 96.7% of the Mtb complex strains (204/211) were correctly assigned as MTB complex and 91.7% (22/24) NTM species were correctly assigned based only on intact bacteria species-specific lipid profiling by MALDI-ToF MS.ConclusionsIntact bacterial lipid profiling provides a biosafe and unique route for rapid and accurate mycobacterial identification. 相似文献
45.
Clinical nurse educators in a BSN program developed the SIM-PLE (Simulation-Positive Learning Evaluation) rubric to evaluate student performance in simulation. A pilot study was conducted over two semesters with junior level medical-surgical classes made up of approximately 110–130 students each semester, and the tool was revised and re-evaluated. Inter-rater reliability testing utilized 69 SIM-PLE rubric student evaluations (N = 69). Inter-rater reliability was assessed with comparison of lead faculty with three other instructors utilizing two raters for each simulation experience. The intraclass correlation coefficient (ICC) suggested high inter-rater reliability. The t-test difference was not significant. One-way analysis of variance (ANOVA) showed a significant difference in the Collaboration subcategory score. Univariate ANOVA indicated both raters scored consistently with each other overall and that they both scored JR1 differently than JR2. The pilot study and testing of interrater reliability of the rubric revealed positive findings. The role of the rubric in providing formative feedback during debrief sessions empowered students to analyze their own performance and/or experience to self-correct or improve their future practice based on these experiences. 相似文献
46.
AimThis study presents a workshop on the Situation Model Nursing Education Action program, examines how to promote gender awareness and decrease barriers related to differences in gender friendliness through the implementation of this program and tracks the trends of the relevant variables.DesignPre- and post-observations and a cohort study were conducted.MethodsA total of 58 nursing students (42 females and 16 males) were included. Nursing students were offered a gender-care intervention as two 90-minute workshops and surveys that measure gender awareness and gender friendliness were administered.ResultsThe results concerned gender-bias awareness and gender-friendliness barriers scores across the four weeks of the program intervention, with the generalized estimated difference score compared with the Week 1 baseline. Mean student scores showed that gender-bias awareness was significantly decreased at Week 2 (p < .001) and Week 4 (p < .001) and that mean gender-friendliness barrier scores significantly declined at Week 4 (p < .001).ConclusionsThe findings indicate that a faculty professional learning community workshop that facilitates intentional behavioral change can help faculty to become aware of gender bias, which can improve students’ gender awareness through clinical case discussion and lead to a decline in barriers to students’ gender friendliness. 相似文献
47.
48.
目的 检索、分析和汇总妊娠相关静脉血栓栓塞症(pregnancy associated venous thromboembolism,PA-VTE)评估与预防的最佳证据,为临床中完善对PA-VTE患者的管理提供参考。 方法 检索UpToDate、BMJ Best Practice、Embase、Springer Link等网站或数据库中关于PA-VTE评估与预防的所有证据,包括指南、系统评价、最佳临床实践信息册、证据总结、专家共识等。检索时限为2015年1月—2021年5月。由2名研究人员独立进行文献评价,4名研究人员进行证据提取、翻译及整合。 结果 共纳入11篇文献,其中指南4篇、临床决策1篇、专家共识3篇、系统评价3篇。从PA-VTE危险因素的评估、评估时机、评估工具、基础预防、物理预防、药物预防、健康宣教7个方面总结20条证据。 结论 该研究总结了PA-VTE评估与预防的最佳证据,建议制订符合本国国情的PA-VTE风险评估工具,筛查相关危险因素并分层管理,加强孕产妇PA-VTE健康教育,以达到降低发生率的目标。 相似文献
49.
目的 比较NCRP伤口生物动力学模型和ICRP 78号报告推荐的注入模式下伤口摄入超铀核素所致内照射剂量的差异,了解器官剂量的分布特性。方法 以241Am(M类,颗粒态)为例计算了上述两种不同模型模式下工作人员伤口摄入单位活度后所致人体各组织器官当量剂量和待积有效剂量,及其在部分器官(肝、骨等)和部分生物样品(尿、粪等)中的滞留/排泄分数曲线。结果 工作人员经由伤口摄入单位活度241Am所致待积有效剂量的两种模型计算结果相差约为18.5%;器官当量剂量由高到低依次为骨表面,肝和红骨髓;伤口摄入单位活度241Am后全身滞留分数较高,不易排出,在骨和肝中的滞留分数随时间推移而显著升高,而在尿、粪中的排泄分数则较低且变化较小。结论 利用现有的两种模型估算超铀核素伤口污染所致的内照射剂量尚有较大的差异,值得继续深入开展研究。 相似文献
50.