全文获取类型
收费全文 | 4109篇 |
免费 | 433篇 |
国内免费 | 112篇 |
专业分类
耳鼻咽喉 | 31篇 |
儿科学 | 118篇 |
妇产科学 | 87篇 |
基础医学 | 253篇 |
口腔科学 | 106篇 |
临床医学 | 420篇 |
内科学 | 913篇 |
皮肤病学 | 80篇 |
神经病学 | 457篇 |
特种医学 | 148篇 |
外科学 | 670篇 |
综合类 | 304篇 |
现状与发展 | 1篇 |
预防医学 | 407篇 |
眼科学 | 32篇 |
药学 | 282篇 |
中国医学 | 126篇 |
肿瘤学 | 219篇 |
出版年
2023年 | 105篇 |
2022年 | 118篇 |
2021年 | 194篇 |
2020年 | 211篇 |
2019年 | 230篇 |
2018年 | 256篇 |
2017年 | 188篇 |
2016年 | 183篇 |
2015年 | 174篇 |
2014年 | 334篇 |
2013年 | 308篇 |
2012年 | 214篇 |
2011年 | 269篇 |
2010年 | 193篇 |
2009年 | 186篇 |
2008年 | 205篇 |
2007年 | 165篇 |
2006年 | 155篇 |
2005年 | 116篇 |
2004年 | 106篇 |
2003年 | 100篇 |
2002年 | 79篇 |
2001年 | 56篇 |
2000年 | 45篇 |
1999年 | 53篇 |
1998年 | 32篇 |
1997年 | 24篇 |
1996年 | 39篇 |
1995年 | 33篇 |
1994年 | 28篇 |
1993年 | 28篇 |
1992年 | 20篇 |
1991年 | 23篇 |
1990年 | 19篇 |
1989年 | 14篇 |
1988年 | 20篇 |
1987年 | 8篇 |
1986年 | 11篇 |
1985年 | 21篇 |
1984年 | 18篇 |
1983年 | 9篇 |
1982年 | 10篇 |
1981年 | 14篇 |
1980年 | 13篇 |
1979年 | 2篇 |
1978年 | 8篇 |
1977年 | 2篇 |
1976年 | 8篇 |
1975年 | 5篇 |
1973年 | 1篇 |
排序方式: 共有4654条查询结果,搜索用时 187 毫秒
11.
12.
13.
Roberto L. Cazzato Pierre De Marini Ian Leonard-Lorant Danoob Dalili Guillaume Koch Pierre A. Autrusseau Theo Mayer Julia Weiss Pierre Auloge Julien Garnon Afshin Gangi 《Diagnostic and interventional imaging》2021,102(6):355-361
PurposeTo retrospectively report on safety, pain relief and local tumor control achieved with percutaneous ablation of sacral bone metastases.Materials and methodsFrom February 2009 to June 2020, 23 consecutive patients (12 women and 11 men; mean age, 60 ± 8 [SD] years; median, 60; range: 48-80 years) with 23 sacral metastases underwent radiofrequency (RFA) or cryo-ablation (CA), with palliative or curative intent at our institution. Patients’ demographics and data pertaining to treated metastases, procedure-related variables, safety, and clinical evolution following ablation were collected and analyzed. Pain was assessed with numerical pain rating scale (NPRS).ResultsSixteen (70%) patients were treated with palliative and 7 (30%) with curative intent. Mean tumor diameter was 38 ± 19 (SD) mm (median, 36; range: 11-76). External radiation therapy had been performed on five metastases (5/23; 22%) prior to ablation. RFA was used in 9 (39%) metastases and CA in the remaining 14 (61%). Thermo-protective measures and adjuvant bone consolidation were used whilst treating 20 (87%) and 8 (35%) metastases, respectively. Five (22%) minor complications were recorded. At mean 31 ± 21 (SD) (median, 32; range: 2-70) months follow-up mean NPRS was 2 ± 2 (SD) (median, 1; range: 0–6) vs. 5 ± 1 (median, 5; range: 4–8; P < 0.001) at the baseline. Three metastases out of 7 (43%) undergoing curative ablation showed local progression at mean 4 ± 4 (SD) (median, 2; range: 1-8) months follow-up.ConclusionPercutaneous ablation of sacral metastases is safe and results in significant long-lasting pain relief. Local tumor control seems sub-optimal; however, further investigations are needed to confirm these findings due to paucity of data. 相似文献
14.
15.
16.
17.
18.
由于高分辨率胸部CT和肺癌早期筛查的普及,同期多原发肺癌(或称同时性多原发肺癌,synchronous multiple primary lung cancer,sMPLC)的检出率逐步提高。sMPLC与肺癌肺内转移的鉴别诊断成为尤其重要的临床问题。借助高通量测序技术刻画sMPLC的分子遗传学特征是目前研究的热点,既能阐释sMPLC的发生发展规律,也可作为临床病理诊断标准的补充和完善。本文对sMPLC诊断标准的更新进行总结,并以克隆性分析领域为例,综述sMPLC分子遗传学特征的研究进展。 相似文献
19.
《中华创伤杂志(英文版)》2022,25(3):170-176
ProposeIn this study, we re-assessed the criteria defined by the radiological society of North America (RSNA) to determine novel radiological findings helping the physicians differentiating COVID-19 from pulmonary contusion.MethodsAll trauma patients with blunt chest wall trauma and subsequent pulmonary contusion, COVID-19-related signs and symptoms before the trauma were enrolled in this retrospective study from February to May 2020. Included patients (Group P) were then classified into two groups based on polymerase chain reaction tests (Group Pa for positive patients and Pb for negative ones). Moreover, 44 patients from the pre-pandemic period (Group PP) were enrolled. They were matched to Group P regarding age, sex, and trauma-related scores. Two radiologists blindly reviewed the CT images of all enrolled patients according to criteria defined by the RSNA criteria. The radiological findings were compared between Group P and Group PP; statistically significant ones were re-evaluated between Group Pa and Group Pb thereafter. Finally, the sensitivity and specificity of each significant findings were calculated. The Chi-square test was used to compare the radiological findings between Group P and Group PP.ResultsIn the Group PP, 73.7% of all ground-glass opacities (GGOs) and 80% of all multiple bilateral GGOs were detected (p < 0.001 and p = 0.25, respectively). Single bilateral GGOs were only seen among the Group PP. The Chi-square tests showed that the prevalence of diffused GGOs, multiple unilateral GGOs, multiple consolidations, and multiple bilateral consolidations were significantly higher in the Group P (p = 0.001, 0.01, 0.003, and 0.003, respectively). However, GGOs with irregular borders and single consolidations were more significant among the Group PP (p = 0.01 and 0.003, respectively). Of note, reticular distortions and subpleural spares were exclusively detected in the Group PP.ConclusionWe concluded that the criteria set by RSNA for the diagnosis of COVID-19 are not appropriate in trauma patients. The clinical signs and symptoms are not always useful either. The presence of multiple unilateral GGOs, diffused GGOs, and multiple bilateral consolidations favor COVID-19 with 88%, 97.62%, and 77.7% diagnostic accuracy. 相似文献
20.
《The Journal of arthroplasty》2022,37(4):721-726
BackgroundPreoperative anemia (POA) is a significant predictor for adverse outcomes in primary total hip arthroplasty (THA). Current literature has studied POA stratified by severity. This study aims to find a threshold preoperative hemoglobin (Hb) value for increased risk of adverse outcomes in THA.MethodsThis is a retrospective analysis of primary THA patients with preoperative Hb values from 2014 to 2021 from an academic orthopedic specialty hospital. Demographics, surgical data, and postoperative outcomes were collected. Patients without preoperative Hb values within the electronic health record system or values acquired >30 days preoperatively were excluded. Patients were grouped based on POA severity using World Health Organization criteria. Secondary analysis using discrete preoperative Hb values was performed. P-values were calculated using analysis of variance/Kruskal-Wallis and chi-squared/Fisher’s exact testing with P < .05 considered significant.ResultsA total of 1347 patients were included: 771 (57.2%) patients with POA and 576 (42.8%) with normal preoperative Hb. In the POA group, 292 (37.9%) were mild, 445 (57.7%) moderate, and 34 (4.4%) severe. Increased length of stay was seen in moderate (3.9 ± 4.3 vs 2.4 ± 2.1, P < .001) and severe (5.0 ± 3.4 vs 2.4 ± 2.1, P < .0001) groups compared to control. The severe group had higher 90-day readmission and revision rates compared to control. Analysis by discrete Hb values showed increased length of stay in Hb values <11 g/dL and a greater proportion of patients with Hb values <12 g/dL were discharged to skilled nursing facilities.ConclusionPatients with preoperative Hb <12 g/dL should be assessed for other risk factors that may predispose them to postoperative complications. Further investigation is warranted to develop more robust perioperative management strategies for POA patients undergoing THA.Level III EvidenceRetrospective Cohort Study. 相似文献