依托芬那酯凝胶治疗关节痛的多中心随机开放对照研究

目的：以双氯芬酸钠乳膏为对照,研究依托芬那酯凝胶对关节痛患者的疗效及安全性。方法：150例关节痛患者随机分成试验组（依托芬那酯凝胶凝胶）和对照组（双氯芬酸钠乳膏）,临床观察时间为1周。对两药治疗前后关节疼痛、压痛、活动痛和研究者对总体疗效的评价进行比较。结果：两组在治疗1周时平均关节疼痛、压痛和活动痛的变化及起效时间差异无统计学意义;两组的不良事件发生率差异无统计学意义,两组皆无严重不良事件发生。结论：依托芬那酯凝胶与双氯芬酸钠乳膏对关节痛的止痛作用和不良反应相似,无严重不良事件发生。     

胃三针结合健胃舒颗粒治疗脾虚气滞型功能性消化不良疗效观察

[目的]探讨胃三针结合健胃舒颗粒治疗脾虚气滞型功能性消化不良的临床疗效。[方法]将43例患者按随机数字表法分为治疗组22例和对照组21例。治疗组采用针刺中脘、足三里、内关,并口服健胃舒颗粒;对照组予枸橼酸莫沙必利口服。共治疗4周,观察和比较两组症状积分、疗效指数、水负荷试验和生活质量(SF-36)得分的差异变化。[结果]治疗组的总有效率为86.36%,与对照组比较差异有统计学意义(P0.05);治疗后两组的症状积分均有下降,水负荷试验得分、生活质量得分均升高,组间比较,治疗组改善更明显,差异有统计学意义(P0.05)。[结论]胃三针结合健胃舒颗粒治疗脾虚气滞型FD症状改善明显,疗效确切,值得临床广泛推广。     

Is there a correlation between arthroscopic findings and the clinical signs and symptoms of patients with internal derangement of the temporomandibular joint? A prospective study

The aim of this study was to evaluate the correlation between clinical signs and symptoms of patients with internal derangement of the temporomandibular joint (TMJ) and arthroscopic findings. The study included a sample of 67 patients who underwent TMJ arthroscopy. The variables evaluated were the arthroscopic findings of synovitis, chondromalacia, adhesion, and roofing. The Spearman correlation index was used to correlate these findings with the clinical signs and symptoms of internal derangement of the TMJ, namely maximum mouth opening, pain (visual analogue scale, VAS), and the Wilkes classification. The mean age of the population was 36.16 years, and 85% were female. There was a correlation between pain and synovitis (P = 0.0029, r = 0.3508), between mouth opening limitation and the amount of adhesion (P = 0.0004, r = ?0.4084), and between Wilkes classification and the presence of chondromalacia and disc displacement (P = 0.001, r = 0.374 and P = 0.0045, r = ?0.3357, respectively). No correlation was found between age and the presence of chondromalacia (P = 0.3444, r = 0.1147). Patients who had worse pain symptoms had more advanced stages of synovitis, and the increased presence of adhesions was associated with limitations in mouth opening. Furthermore, those with more advanced Wilkes stages had greater disc displacement and more severe stages of chondromalacia.     

"先安未受邪之地"思想在顽痹治疗中的运用

"先安未受邪之地"思想在顽痹临床论治同样具有深远意义.顾护常人之脾胃,并于患者肝肾、脾胃脏腑亏损相关症状出现早期,予辛温苦燥之品祛风、散寒、除湿调补脾胃,益肝肾有早晚之别,早期重"补阳",稳定期及后期则以"滋阴"为主.治疗中利湿活血防痰瘀互结,减缓关节损伤,提升患者生活质量.     

追风透骨丸治疗痹病230例临床疗效观察

目的：观察追风透骨丸治疗痹病的临床疗效。方法：口服追风透骨丸,每次６ｇ,每日２次,３０ｄ为一疗程。结果：有效率为９１．７４％,其中显效以上占５０％,对痹病患者的症状体征有明显的改善作用。结论：追风透骨丸治疗痹病属于风寒湿痹证者,疗效确切,且安全可靠。     

关节镜下膝关节腔冲洗及骨穿刺减压治疗膝痛症

目的 探讨关节镜下行膝关节内骨穿刺减压和冲洗关节腔治疗膝痛症的疗效。方法 对３２例（４４膝）骨性关节炎患者及１２例（１６膝）休息痛患者,行膝关节镜检查,并在关节镜下行骨穿刺减压和关节液冲洗关节腔。术后３个月及１年后复查,了解膝关节疼痛、肿胀及活动功能的改善情况。结果 治疗后膝关节疼痛缓解、肿胀减轻、功能改善。术后３个月复查,优良率达８２％;经１年以上随访,优良率为７３％,无复发及并发症。结论 关节     

王耀光教授治疗痹证经验撷萃

痹证是临床常见肢体经络病之一,临床表现多样、病情复杂,患者常疼痛难忍,严重影响日常工作与生活。王耀光教授认为痹证的病因病机为邪阻经络、脏腑气血精液亏虚,治疗上常选用经方加减,善用虫类药、藤类药且注意肝肾的调护。本文主要介绍王耀光教授治疗痹证的临床经验。     

中医辨治类风湿关节炎研究概况

从病因病机、辨证论治等方面,综述中医辨治类风湿关节炎的研究概况。各种辨治方法相互渗透。     

蚓激酶国内研究文献回顾

目的研究百奥蚓激酶临床观察、研究的文献,分析其临床用药的安全性、有效性。方法检索国内医学文献数据库,收集1994年1月～2009年6月期间有关蚓激酶的文献报道54篇,对每篇文献的发表期刊、年限、第一作者、回顾性研究文献、临床观察性文献、观察病例数、患者年龄、性别、疾病病程、用药疗程、合并用药情况、观察指标、结果和有效率、不良反应发生情况等资料进行统计分析。结果共纳入54篇文献,27篇关于治疗急性脑梗死的文献、13篇治疗其他心血管疾病的文献、10篇治疗糖尿病并发症的文献、4篇治疗其他疾病的文献。结论蚓激酶是一种临床疗效肯定、不良反应小、可靠性强的降纤药品。