基于Blog思想构建协作式学习资源库

如何在网络教学环境下充分发挥协作式学习的特点?文章从Blog(即网络日志)这一新的交流方式得到启发,探讨了基于Struts框架构建协作式学习资源库的原理及其实现过程.     

脑电图自动诊断研究

目的：本文介绍一种新的脑电图自动诊断系统。方法：它基于一种能识别脑电图波形特征、波幅分布、脑波周期特性和脑波节律特征的分析算法实行脑电特征抽取，再应用一种非线性几何分类识别算法（Ｋ 近邻法）进行脑电图的定量诊断。结果：对３０９例成年人脑电图随机划分为训练组和考核组，应用该脑电图自动诊断系统和脑电图医师人工诊断对照分析，在正常脑电图和轻度异常脑电图之间的正确判别率在训练组是９５．５％，考核组是６４．７％；在考核组的正常脑电图和轻度异常脑电图之间，正常脑电权重指数的判别效果的Ｚ分数是１．４９，轻度异常脑电权重指数的判别效果的Ｚ分数是１．４３（这意味着正确诊断率大于９０％）。结论：以上结果说明该方法已达到临床实用的价值。该系统也能够应用于辨别其它类型脑电图，还具有简便的在线自学能力。     

胃癌生长中组织学类型和生长方式的变化

通过62例粘膜下层早期胃癌和342例进展期癌的光镜观察，发现：1，部分胃癌在向深层发展中，组织学类型可以转变；2，胃癌生长方式与癌组织所在部位（层次）、组织学类型有关，同一病例粘膜层癌和深层癌的生长方式可以不同。结论：胃癌的生长是一个动态变化过程．形态学上表现为组织学类型和生长方式的改变。     

Value recognition and eating patterns of Kimchi in female middle school students and their mothers

This study analyzed Kimchi eating culture in 178 households with female middle school children located in Incheon and Seosan areas, investigated the Kimchi eating patterns of female middle school students, and also analyzed the differences in value recognition for Kimchi between mothers and their female middle school students. Results showed that 23.0% of subject households answered eat Kimchi at every meal and the main reason for eating Kimchi in most households was good for taste. Most households made their own Kimchi, and only 12.3% of households bought Kimchi. Subject households preferred hot and spicy taste (34.8%) and pleasing taste (20.2%), and 44.4% of middle school children answered as eating Kimchi at every meal, and the source for information on Kimchi was home in 51.6% and mass media in 33.7%, suggesting the lack of school education. Both mothers and their female middle school students placed high value on Kimchi for its nutritional aspect and on Kimchi from the market for its convenience. Mothers showed significantly higher value (p<0.05) on the storage aspect of Kimchi compared to their middle school students, and female middle school students showed significantly higher value (p<0.05) on the value recognition for Kimchi as an international food compared to their mothers. Also, the value for hot pepper powder was high among other additional ingredients, and both mothers and middle school students had high values for Kimchi stew among other food dishes using Kimchi, and middle school students showed higher values (p<0.001) on foreign dishes using Kimchi such as Kimchi pizza and Kimchi spaghetti compared to the mothers group. Therefore, based on these results, the development of educational programs on Kimchi is needed not only at home but also at schools, by re-emphasizing the importance of value recognition for KImchi in our food culture.     

Argyrophilic nucleolar organizer region (AgNOR) area per nucleus as a prognostic factor in breast cancer

Whether argyrophilic nucleolar organizer region (AgNOR) is a predictor of prognosis in breast cancer is controversial. The semiquantitative procedure used to calculate interphasic argyrophilic dots optically is neither reliable nor reproducible. We measured the mean area of AgNOR dots, the mean AgNOR area per nucleus (MA), and the mean AgNOR number per nucleus (MN) by automated image analysis in specimens from 131 patients with breast cancer. Higher MA (>7.41 pun²), detected in 22 (16.8%) of 131 patients, did not correlate with clinicobiologic variables, except for DNA ploidy status. Overall survival was significantly better in patients with lower MA than in those with higher MA. On multivariate analysis, MA was a significant independent factor, followed by nodal status. These findings indicate that expression of AgNOR should be evaluated in terms of area occupied and that the mean area of AgNOR per nucleus (MA) is an important prognostic factor in the overall survival of breast cancer patients. © 1995 Wiley-Liss, Inc.     

78例垂体瘤的眼部表现临床分析

目的：探讨垂体瘤的眼部表现。方法：对78例垂体瘤患者进行视力、眼底、荧光素眼底血管造影(fundus fluorescein angiography，FFA)、视野、及图形视诱发电位(pattern visual evoked potential，PVEP)检查。结果：视力下降占76．9％；眼底视神经病变占51．9纷，视野损害占67．3％，PVEP异常占89．2％。23．1％患者以眼部异常表现为首诊症状，其中19．2％曾被诊断为眼科疾病。结论：对不明原因视力下降、视野缺损或视神经病变的患者，应常规进行视力、视野、眼底及PVEP检查，结合鞍区CT或MR，避免漏诊、误诊。     

急性前壁心肌梗死梗死区心电图ST段形态的预后价值

目的 探讨急性前壁心肌梗塞梗塞区心电图ST段形态的预后价值。方法 比较弓背向上与弓背向下2型ST段抬高病人发病1月内发生的空性早搏、空性心动过速、心空颤动、急性左心衰竭、死亡及高血压、心绞痛史的差别。结果 2组室性早搏、室性心动过速、合并高血压无明显差别，ST段弓背向上组室颤、急性心衰、死亡及有心绞痛史者显著高于ST段弓背向下组(P＜0．05或P＜0．01)。结论 急性前壁心梗ST段弓背向上抬高较弓背向下抬高严重、并发疙多、预后较差。     

轴型皮瓣在真性肛门瘢痕狭窄畸形治疗中的应用

目的:介绍应用邻位轴型皮瓣治疗真性肛门瘢痕狭窄畸形的方法和经验.方法:在15例真性肛门瘢痕狭窄畸形患者手术过程中,设计以直肠下动脉皮支或阴囊(唇)后动脉为轴心血管的轴型皮瓣,环形覆盖切除瘢痕后形成的肛周创面.结果:15例患者术后肛周皮瓣完全成活,肛门狭窄解除,肛周局部外观满意,排便及活动功能基本恢复正常.结论:使用邻位轴型皮瓣治疗真性肛门瘢痕狭窄畸形有手术损伤范围小,皮瓣成活率高,功能外形恢复好等优点,是治疗肛门瘢痕狭窄畸形的一种较好的手术方法.     

干扰素治疗慢性乙肝反应的研究

目的：总结干扰素治疗慢乙肝的反应规律及特点。方法：150例慢乙肝患者随机分为干扰素治疗组和一般扩肝的对照组。采用前瞻性研究方法，对治疗组患者定期连续进行肝功能试验、HBV DNA斑点杂交检测、HBV DNA定量PCR检测、乙肝病毒标记物检测。结果：干扰素治疗过程中，转氮酶总体呈下降趋势；HbeAg应答与患者治疗前转氮酶有关，转氮酶重中度升高患者下降明显；用药前HBV DNA阳性患者、开始用药后第2月末HBV DNA转阴者，HbeAg转阴率较高。HbeAg应答大多发生在治疗第3月左右，平均转时间为3.4月；干扰素治疗前HB VDNA女性低于男性，HbeAg应答组低于无应答组。治疗过程中HBV DNA在总体上呈下降趋势，转阴平均时间为1.9月，与HbeAg应答及肝功能恢复有一定相关性。结论：干扰素对慢性肝炎治疗有效。     

二尖瓣返流对扩张型心肌病患者的左室充盈模式的影响

目的 :探讨二尖瓣返流对扩张型心肌病 (DCM)患者左室充盈的影响。方法 :对 30例有轻度二尖瓣返流的DCM患者和 30例二尖瓣返流较重的DCM患者与 30例正常人的舒张期二尖瓣口血流超声心动图检查结果进行分析。结果 :反映左室舒张功能的二尖瓣血流频谱早期充盈峰速度 (VE)、晚期充盈峰速度 (VA)、VE/VA等参数在轻微二尖瓣返流组与对照组比较有明显差异 (P <0 .0 0 0 1) ,而严重二尖瓣返流组上述参数与对照组相比却无显著差异 (P >0 .0 5 )。结论 :超声心动图二尖瓣口血流指标显示二尖瓣返流轻微的DCM患者左室主动充盈减弱 ,被动充盈相对增加 ,而对二尖瓣返流较重的DCM患者的VE/VA却表现为假性正常化。