La maladie de Sinding-Larsen et Johansson

The Sinding-Larsen and Johansson disease is a non-negligible cause of gonalgia among children of 10 to 14, often misinterpreted as « growing pain . The disease is a benign pathology of the lower pole of the patella which occurs preferentially in physically active children. Our study, carried out in conjunction with the medical department INSEP, is based on a literature review as well as an analysis of 14 cases over two years. The present work eventually led to the differentiation of four etiopathological categories accounting for all the radiochemical evolutions observed. At the origin of these four categories, two factors coexist: the local fragility (the presence of cartilage at the lower pole of the patella) and the trigerring factor, which is most often sports practice. This explains why among children practicing sports, even intensively, only few suffer from this disease.It is essential to know the different radiological aspects of the normal patella in children, in order not to misinterpret one of these aspects with the Sinding-Larsen and Johansson disease.Always benign, the Sinding-Larsen and Johansson disease can very seriously disturb the « careerof children, engaged in high-level sports activity, the average time of evolution being seven months.     

吉林省七年鼠情监测结果分析

吉林省经七年来的鼠情监测,基本查清与人们接触密切的鼠类,特别是传播疾病的主要鼠类的分布规律,分析出我省家鼠有两个高峰(6月和10～11月),野鼠也有两个高峰(6月和10月),这与我省流行性出血热两个高峰相吻合,鼠峰在病峰之前。1986年以后,由于我省开展大规模灭家鼠活动,家鼠高峰已不存在规律性。通过几年来的灭鼠活动,使家鼠密度呈下降趋势,城镇褐家鼠和小家鼠构成比发生变化。城镇未爆发家鼠型流行性出血热。鼠情监测为灭鼠防病工作提供了科学依据。     

荧光分光光度法测定水产品中烷烃类、芳烃类污染物

目的：对使用荧光分光光度法测定水产品中烷烃类、芳烃类污染物的方法进行验证,并检测三类样品。方法：通过氢氧化钠-乙醇皂化处理,用正已烷萃取,用石油醚溶解,测量萃取物荧光强度值进行定量。结果：测得标准油在0.00～12.0μg/ml范围内线性关系良好,相关系数0.9999,检出限为0.2 mg/kg,平均回收率90.2%,RSD5.4%。结论：本法准确度、灵敏度高,检出限低,操作稳定性好。     

公共服务体系与中韩公共管理改革

公共服务体系是现代文明社会的基本标志，也是现代社会稳定发展的基础，公共经济学和欧美国家的发展经验已经证明了这一点。韩国是从上世纪80年代取得“汉江奇迹”后，在经济增长成就和产生的社会问题的双重推动下，开始了以奉侍型政府、国民中心等为目标的管理改革，并逐步建立起比较完善的公共服务体系。中国在进入新世纪后提出建设服务型政府，开始建立和完善公共服务体系。研究表明，在建立公共服务型政府的改革中，两国在价值理念、改革目标、改革路径和举措等方面都有许多相同相似的方面，但也存在差异性。总体上，韩国在建立公共服务型政府，提高公共服务质量等方面要比中国先行一步，有许多值得中国政府学习和借鉴的地方。     

动物细胞培养过程中pH和溶氧的关联控制

本文通过对动物细胞培养过程中pH值和溶氧(DO)水平控制要求的分析,设计了用空气、氧气、氮气和二氮化碳四组气体关联控制pH值和DO水平的控制系统。该系统根据对瞬时pH值和DO值参数的检测,通过微处理机进行一系列的逻辑判断和具有PI调节规律的DDC增量词节计算,再经四气体关联互补计算和多重时序控制环节,综合调节四组气体电磁阀的相互开闭时间,实现对培养过程中pH值和DO水平的控制,满足动物细胞生长的需要。     

Modulation of infection-induced inflammation and locomotive deficit and longevity in senescence-accelerated mice-prone (SAMP8) model by the oligomerized polyphenol Oligonol.

Oligonol is produced from the oligomerization of polyphenols (typically proanthocyanidin from a variety of fruits such as lychees, grapes, apples, persimmons, etc.) and contains catechin-type monomers and oligomers of proanthocyanidins. The ability of Oligonol to affect infection-dependent eye inflammation, locomotion and longevity in senescence-accelerated prone mice (SAMP8) (a model of senescence acceleration and geriatric disorders with increased oxidative stress and neuronal deficit) was investigated. Oligonol (60mg/kg) significantly modulated the extent of inflammation scores in the eye of SAMP8 mice. Examination of the mice indicated infection with mouse hepatitis virus and pinworm (Syphacia obvelata) in both males and females and with the intestinal protozoa (trichomonad) in males. A comparison of the two groups (using log-rank test) and the difference in the mean life span between groups (using Student's t-test) indicated significant differences in survival (p=0.043) and the mean life span (p=0.033) in male SAMP8 mice. Oligonol increased the mean life span and this was statistically significant. In the open-field locomotive test, the 7-week-old SAMP8 mice crossed more than 40 partitioned lines in 1min. At 48-week-old control untreated male SAMP8 crossed 2 lines. The Oligonol-treated 48-week-old male SAMP8 mice crossed 17 lines however. The improved locomotive activity was statistically significant even after 36weeks in the Oligonol-treated male SAMP8 but this was not the case throughout the time course of the study in the Oligonol-treated female SAMP8. Thus Oligonol treatment to SAMP8 mice modulated the severity of infection-dependent inflammation, prolonged life-span and significantly improved locomotive activity indicating potential benefit to aging-associated diseases such as Alzheimer's or Parkinson's diseases. This presents potential for further research to define infection-dependent inflammation associated with degenerative conditions and the molecular mechanism of dietary antioxidant protection.     

温针灸为主治疗前列腺增生症疗效观察

笔者于1998年2月～1999年12月应用温针灸为主治疗前列腺增生症51例,效果理想.现报道如下. 1临床资料 1.1病例选择全部98例观察病例均来自男科门诊.按随机法分为治疗组和对照组.其中治疗组51例,年龄最小49岁,最大72岁,平均56.3岁;病程最短2年,最长5年,平均4.1年.对照组47例,年龄最小48岁,最大71岁,平均57.1岁;病程最短3年,最长7年,平均5.0年.两组具有可比性.     

不同病因腹泻病儿肠道主要菌群变化的研究和比较

对８８例不同病因腹泻儿肠道双歧杆菌、乳酸杆菌、大肠杆菌的变化进行研究。对照组２５例。结果：研究组较对照组双歧杆菌、乳酸杆菌有显著下降（Ｐ＜０．０１和Ｐ＜０．０５），大肠杆菌下降不明显（Ｐ＜０．０５）。非感染性腹泻组较感染性腹泻组双歧杆菌、乳酸杆菌下降更显著（Ｐ＜０．０１和Ｐ＜０．０５），大肠杆菌下降不显著（Ｐ＜０．０５）。感染性腹泻组中，双歧杆菌在轮状病毒肠炎组中较急性菌痢下降更显著（Ｐ＜０．０５），而其它两种菌下降程度相差不明显（两者Ｐ＜０．０５）     

白术茯苓汤及其配伍对脾虚大鼠胃肠激素的影响

目的：探讨益气健脾方剂治疗脾虚证的配伍规律。方法：采用苦寒泻下法复制大鼠脾虚模型，运用放射免疫分析法（RIA）检测白术茯苓汤及其与补气药。行气药及除湿药的不同配伍对脾虚大鼠胃泌素（GAS）、胃动素（MTL）及血管活性肠肽（VIP）的含量影响。结果：与正常对照组比较，脾虚模型大鼠GAS、MTL降低（P＜0．01），VIP升高（P＜0．01）；与自然恢复组比较，各治疗组以上部分或全部指标均有不同程度的改善，其中，以综合配伍组改善作用最优。结论：白术茯苓汤的脾虚大鼠胃肠激素的紊乱的某些指标，有一定的改善作用，综合配合组以上指标的改善，优于白术茯苓汤组及其余各配伍组，说明中医关于复方配伍的理论与实践，有其科学价值。     

一种切除部分齿状线和肛管全层的超低位保肛手术

目的介绍一种切除部分齿状线和肛管全层的直肠恶性肿瘤的超低位保肛手术。方法对8例瘤灶下缘距离齿状线小于或等于2cm的直肠超低位恶性肿瘤进行术前评估,对6例患者首先进行术前放疗化疗使肿瘤明显缩小。手术在完成全直肠系膜和(或)盆腔淋巴清扫的基础上,向下切断骶骨直肠韧带,达到肛管直肠肌环上缘,相当于齿状线(直肠肛管交界处)水平。如果癌下缘远侧正常肠管长度仍小于2cm,可沿外括约肌环和肠壁之间再向下分离1～2cm。肛门手术组充分显露肿瘤部位,在直肠癌向下侵犯最低侧所在的1/2象限,于癌灶下缘2cm处垂直于肛管长轴切开肛管全层,然后沿外括约肌环向上游离,切除癌侧部分齿状线,与腹部手术组会师,在没有癌灶或癌侵犯较高的一侧,则沿齿状线上缘切断直肠。游离横结肠脾区并在降结肠远切端作长5cm的“J”形结肠储袋,将结肠储袋向下脱出至肛管断端,与癌灶侧肛管、癌灶对侧的齿状线用3-0可吸收线间断手工缝合。结果在遵守根治原则的基础上,采用本方法成功地为8例直肠超低位恶性肿瘤患者进行了保肛手术,部分切除齿状线的患者术后肛门功能与Dixon手术患者近似。结论在直肠全系膜切除和盆腔淋巴清扫的基础上,尤其在术前放疗化疗的基础上,切除部分齿状线和肛管全层的保留肛门的手术方法可达到根治要求并保留功能