用科学理论指导"五四一"医院经营管理模式的研究

本文介绍了广东省第二人民医院,用科学理论指导"五四一"医院经营管理模式研究的改革实践.分别阐述了"五四一"医院经营管理模式的研究基础、方向和核心目标.     

Heart health inequalities in Canada: modules, theory and planning

It is well known that prevalence and incidence rates of cardiovasculardisease (CVD) and CVD risk factors are not equally distributedamong socioeconomic groups. Known risk factors account for part,but not all of unequally distributed CVD rates. Socioeconomicconditions and psychosocial dynamics may explain another pareof the increased CVD rates. Theoretically, it may be possibleto lower CVD rates and CVD risk factor prevalence among lowersocioeconomic status (SES) groups by using a community development(socio-environment) strategy directed towards changes in socioenvrronmentalrisk conditions and psychosocial risk factors, rather than CVDrisk factors per Se. This article describes a protocol for sucha strategy based upon the planning work of Canadian health professionals,loosely organized under a project titled ‘Heart HealthInequalities in Canada’ This protocol incorporates baselinedata on CVD and CVD risk factor prevalence, but is premisedon actions negotiated between community organizations and healthauthorities, rather than defined unilaterally by health authorities.As such, program design activities and evaluation will differfrom a more general population-based risk factor reduction strategy.     

运用现代教育理论思想 提高医学课堂教学质量

本文依据三种现代教育理论思想的有益启示,围绕医学高等专科学校课堂教学质量的提升问题,提出以加强教育理论思想研修为突破口,进而采取更新教育观念、狠抓移植应用和改进教法学法来有效提高医学高等专科学校课堂教学质量的新思路。     

Adaptive group sequential design for phase II clinical trials: A Bayesian decision theoretic approach

Bayesian decision theoretic approaches (BDTAs) have been widely studied in the literature as tools for designing and conducting phase II clinical trials. However, full Bayesian approaches that consider multiple endpoints are lacking. Since the monitoring of toxicity is a major goal of phase II trials, we propose an adaptive group sequential design using a BDTA, which characterizes efficacy and toxicity as correlated bivariate binary endpoints. We allow trade‐off between the two endpoints. Interim evaluations are conducted group sequentially, but the number of interim looks and the size of each group are chosen adaptively based on current observations. We utilize a loss function consisting of two components: the loss associated with accruing, treating, and monitoring patients, and the loss associated with making incorrect decisions. The performance of our Bayesian modeling, and the operating characteristics of decision rules under a wide range of loss function parameters are evaluated using seven scenarios in a simulation study. Our method is illustrated in the context of a single‐arm phase II trial of bevacizumab, gemcitabine, and oxaliplatin in patients with metastatic pancreatic adenocarcinoma. Copyright © 2009 John Wiley & Sons, Ltd.     

中药材仿生栽培的理论与实践

采用生态工程和现代农业生产技术,模拟野生药用植物群落的自然生态系统,开展中药材的仿生栽培,是中药材规范化栽培的一种新模式,在中药农业上日益受到重视.中药材仿生栽培是一种生态种植模式,为中药学、农学、园艺学、生态学、农业工程学和管理学等多学科的交叉与融合,在促进中药资源的可持续利用,改善生态环境和实现人与自然的和谐共处方面有着显著优势,在中药材生产上应大力发展和推广.     

从五行学说探讨全心衰竭与脏腑的关系

心力衰竭的发生、发展及演变涉及全身多个器官,其发展演变与中医学脏腑之间生克乘侮密切相关,用中医五行学说探讨全心衰竭与脏腑之间的关系,为心力衰竭发生、发展的研究开辟一条新的道路,有利于指导心力衰竭的中医药治疗。     

后现代心理学概观

后现代心理学家反对以往的心理学理论和流派把心理或行为看作是一个独立于研究者的“实体”。后现代心理学的典型特征是反对基础主义和本质主义。它认为心理现象并不是一种“精神实在” ,而是一种文化的社会建构。后现代心理学的理论基础是社会建构论 ,多元文化论、后现代女性心理学都是后现代心理学的重要形式。     

建立具有中国特色的临床医学工程体系势在必行

我们提出了一个建立具有中国特色的临床医学工程体系新理念，并且提出了一些具体建设性的意见。它涉及到政府行政管理、医学院校教育、医院科室人员配置以及传统观念的管理模式等，由于理念新、涉及面广，会有许多问题，仅供各界人士共同去探讨。