脑卒中完全性失语患者语言康复训练疗效观察

目的观察脑卒中完全性失语患者的语言康复训练疗效。方法对 10例脑卒中完全性失语的患者进行语言康复训练。结果训练后 ,患者的听理解、呼名、复述、阅读、书写能力评分高于训练前 (P <0 .0 5— 0 .0 1)。结论语言康复训练对脑卒中完全性失语症的康复有积极作用。     

电针对血管性痴呆大鼠血浆和脑组织生长抑素、β-内啡肽含量及学习记忆能力的影响

目的:观察电针对血管性痴呆(VD)大鼠学习记忆能力的影响,探讨电针的治疗作用机制。方法:雄性SD大鼠,随机分为假手术组(n=8)、模型A组(n=8)、模型B组(n=8)、电针组(n=9)、西药组(n=8)。采用4-血管阻断法制作脑缺血模型。电针"百会""大椎""脾俞""肾俞"穴,施以连续波,频率150 Hz,强度约1 mA,留针20 min,每日1次,连续治疗15 d。尼莫通治疗按12 mg/kg、20 ml/kg灌胃。以Morris水迷宫测定大鼠学习记忆能力,并用放射免疫法测定血浆和脑组织生长抑素(SS)、β-内啡肽(-βEP)的含量。结果:模型组大鼠血浆和脑组织中SS的含量及脑组织中-βEP的含量显著降低,与假手术组相比差异有显著性意义(P<0.01),血浆中-βEP含量无明显变化(P>0.05)。模型组大鼠表现明显的学习记忆能力障碍,在水迷宫试验中,其潜伏期显著延长(P<0.01),在原平台象限跨越平台次数与其余3个象限差异无显著性意义(P>0.05)。经电针和西药治疗后潜伏期明显缩短(P<0.01),相同时间内跨越原平台次数明显多于其余3个象限(P<0.01);其血浆和脑组织中SS含量及脑组织中-βEP含量显著升高(P<0.01)。结论:电针能改善VD大鼠血浆和脑组织中的SS、-βEP含量,从而提高VD大鼠学习记忆能力。     

蟾酥对痢疾杆菌抑制作用的研究

研究不同浓度的蟾蜍药液对痢疾杆菌的抑制作用。结果表明，蟾蜍对痢疾杆菌有一定抑制作用，并且随着蟾蜍浓度的升高抑制作用逐渐减弱。     

肝脓肿的现代外科治疗

近年来细菌性肝脓肿仍然是肝脏外科经常遇见的疾病.现代外科的发展丰富了肝脓肿的治疗手段.兰州军区乌鲁木齐总医院自2000年5月至2006年12月共收治肝脓肿61例,报告如下.     

猪腹部火器伤肠管穿透后肝脏功能和形态的变化

目的：观察腹部火器伤肠管穿透后肝脏功能和形态的变化。方法：健康长白创刊猪头随机分为对照组以及伤后1h、2h、4h、8h、12h和24h组．实验组建立腹部火器伤肠管穿透模型后，分别测定伤后1h、2h、4h、8h、12h和24h各组动物血清中ALT、AST水平，并与对照组比较，观察实验组各时间点肝脏组织学变化。结果：伤后各组血清ALT、AST水平均高于对照组，并于伤后2h和12h出现2个高峰。伤后1h、2h、4h组出现逐渐加重的肝细胞水肿、变性，伤后8h、12h、24h组出现逐渐加重的肝细胞点状坏死、灶状坏死、炎细胞浸润。对照组光镜下未见明显的损伤性变化。结论：腹部火器伤肠管穿透导致肝脏出现功能和形态的损伤性变化脯着伤后时间的延长而加重。     

针灸治疗经行头痛的临床研究进展

正经行头痛是指女性每值经期或行经前后出现的以头痛为主的病症,严重者剧痛难忍~([1]),相当于现代医学的"月经性偏头痛"。据调查,经期头痛约占女性偏头痛的56%~([2])。近年来,随着现代生活节奏加快,女性职业竞争力增大,加之精神紧张,经行头痛的发病率也逐年上升,严重影响着年轻女性的日常学习、工作和生活。临床针灸治疗经行头痛疗效显著[3-4],现将近10年来针灸治疗经行头痛的文献综述如下。     

INFLUENCE OF ELECTROACUPUNCTURE ON THE ULTRASTRUCTURE OF CA3 REGION OF THE HIPPOCAMPUS IN VD RATS

Objective: To observe the effect of electroacupuncture (EA) on learning and memory abilities and ultrastructure of synapses in CA3 region of the hippocampus in vascular dementia (VD) rats. Methods: A total of 32 SD rats were randomized into control (sham-operation, n = 7), model (n = 7), EA (n = 9) and medication (n=9) groups. VD model was established by occlusion of the bilateral vertebral arteries (electrocoagulation) and bilateral common carotid arteries (occlusion for 5 min and reperfusion for 10 min, repeated the procedure for 3 times to induce global ischemia). EA (150 Hz, 1 mA) was applied to “Baihui“(百会GV 20), “Geshu“(膈俞 BL 17), “Pishu“(脾俞 BL 20) and “Shenshu“(肾俞 BL 23) for 20 min, once daily and continuously for 15 days. In medication group, the rats were fed with Nimotong (12 mg/kg), once daily and continuously for 15 days. Morris water maze method was used to test the animals‘ learning and memory abilities (latencies to find the hidden platform determined by place navigation trials, and latencies to cross on the location of the removed platform determined by spatial probe trials) after the treatment. Ultrastructural changes (numerical density, NA,surface density, Sv and volume density, Vv) of Gray type 1 synapses in CA3 region of the hippocampus were observed by using transmission electronic microscope and automatic image analysis system. Results: 1 ) Place navigation test showed that in comparison with control group, the average escape latency of VD group was significantly longer (P＜0.01), while in comparison with VD group, the latencies of both EA and medication groups decreased significantly ( P＜0.01 ). No significant difference was found between EA and medication groups in the escape latency (P＞0.05). 2) Spatial probe-test displayed that in comparison with control group, the times which the animals crossed the target platform in VD group decreased significantly (P＜0.01), while compared with VD group, those of both EA and medication groups increased considerably (P＜0.01 ). No significant differences were found between EA and medication groups in the times for rats to cross the target quadrant and among the 4 groups in the times for rats to cross the other quadrants. 3) Compared with control group, NA, Sv, and Vv of VD group decreased significantly (P＜0.01 ), while in comparison with VD group, the 3 indexes of both EA and medication groups increased significantly (P＜0.01), no significant differences were found between EA and medication groups in these 3 indexes (P＞0.05). Conclusion: EA can restrain the loss of Gray type Ⅰ synapses in CA3 region of the hippocampus to improve learning and memory abilities in VD rats.