百赛诺对慢性乙型肝炎患者细胞免疫应答的影响

目的研究百赛诺治疗慢性乙型肝炎(CHB)对患者外周血单个核细胞(PBMC)培养上清IL-4、IL-10和IFN-γ水平的影响。方法选择30例CHB患者给予百赛诺治疗,分别在治疗前、治疗后1个月和3个月抽取全血,同时选择7例健康人群作为对照组。结果CHB组PBMC培养上清分泌IL-4水平显著高于对照组[(17.18±7.43)pg/mlvs(8.24±4.16)pg/ml,P<0.05],而IFN-γ水平则显著低于对照组[(36.25±19.92)pg/mlvs(121.68±44.40)pg/ml,P<0.01)];百赛诺治疗后,在第3个月IFN-γ水平较治疗前显著升高[(53.19±7.28)pg/mlvs(36.25±19.92)pg/ml,P<0.05],IL-4水平则较治疗前显著降低[(9.74±7.75)pg/mlvs(17.18±7.43)pg/ml,P<0.01];HBeAg阳性组百赛诺治疗后IL-4水平较治疗前下降,IFNγ水平较治疗前上升,均有统计学意义[(8.74±6.12)pg/mlvs(20.51±9.16)pg/ml,(50.71±30.76)pg/mlvs(26.03±10.48)pg/ml,P<0.05];而HBeAg阴性组各细胞因子水平治疗前后无明显差异(P>0.05)。结论百赛诺治疗CHB可提高患者Th1型细胞因子、降低Th2型细胞因子水平,在CHB治疗中有一定调节免疫功能的临床价值。     

批量歼强机飞行员健康体检实施的思路探讨（摘要）

目的结合我科对批量歼强机飞行员进行选拔改装体检的组织实施,并对其过程及注意事项进行讨论分析,为选拔改装体检提供参考。方法选择预进行选拔改装体检的xxx名男性现役飞行员,对其进行医学及心理选拔,并对该组织实施过程进行探讨。     

慢性乙型肝炎患者外周血单个河西堡细胞因子检测意义

目的 探讨慢性乙型肝炎(CHB)患者外周血单个核细胞(PBMC)培养上清液中细胞因子的临床意义.方法 采用免疫酶联免疫吸附技术双抗体夹心法检测30例慢性乙型肝炎患者和15例健康对照外周血单个核细胞IL-4、IL-10和IFN-r的水平.结果 CHB组PBMC培养上清分泌IL-4水平显著高于健康对照组(P相似文献   

胸部螺旋CT肺血管造影在肺动脉栓塞诊断中的应用价值

目的 为了提高肺动脉栓塞的诊断率，减少漏诊率。方法 笔者总结了我院2004年10月～2006年12月经螺旋CT肺血管造影确诊为肺动脉栓塞的病人36例，进行回顾性分析。结果 36例均见不同程度的充盈缺损直接征象及肺动脉高压、胸腔积液、肺纹理稀疏和肺斑片状模糊影等间接征象。结论 对比其它检查方法，说明螺旋CT肺血管造影具有无创安全、快速、敏感性高、价格较低，同时还可以诊断胸部其它疾病，有望成为诊断肺动脉栓塞的首选检查方法。     

3．0T磁共振扩散加权成像诊断子宫内膜癌肌层浸润的价值

回顾性分析68例子宫内膜癌的磁共振T2加权像（T2WI）和扩散加权成像（DWI）（b=700s/mm2）图像,由2名MR诊断医师采用单纯T2WI与DWI结合T2WI2种方法盲法随机阅片,分析肿瘤肌层浸润深度,以手术病理结果为标准.统计学分析包括Kappa一致性检验,内膜癌肌层浸润的准确度、敏感度、特异度及受试者工作特征曲线（ROC）分析.2名医师对DWI结合T2WI的阅片一致性好（Kappa =0.818）,2名医师2种方法判断子宫内膜癌肌层浸润深度的准确度、敏感度及特异度：单纯应用T2WI医师甲为61.8％、60.0％、65.2％,医师乙为66.2％、64.4％、69.6％;DWI结合T2WI医师甲为86.8％、84.4％、91.3％,医师乙为89.7％、86.7％、95.7％.2名医师诊断内膜癌深肌层受浸的ROC曲线下面积（AUC）值分别为0.626与0.879、0.670与0.912,DWI结合T2WI均高于单纯应用T2WI （P＜0.01）.3.0 T MR-DWI作为常规T2W]的补充检查序列可以明显提高诊断内膜癌肌层浸润深度的准确性.     

MR检查对聚丙烯酰胺水凝胶隆乳术后并发症的评价

目的：探讨聚丙烯酰胺水凝胶隆乳术后并发症的MRI诊断价值。方法：收集15例聚丙烯酰胺水凝胶隆乳术后患者的乳腺MRI图像，观察乳房假体及其术后并发症的MRI表现。结果：聚丙烯酰胺水凝胶假体2例4只乳房内水凝胶假体完整；13例26只乳房内假体破裂，水凝胶不同程度向周围扩散，乳房皮下、腺体内、乳后间隙、胸肌内见不规则水凝胶分布，高信号水凝胶假体内见多发条带状短T2低信号分隔影。结论：MR检查可准确直观地显示乳房内聚丙烯酰胺水凝胶假体的形态位置及假体破裂的类型、内容物泄漏的位置、范围，为临床手术及随访复查提供全面的信息。     

多层螺旋CT(MSCT)仿真支气管镜对儿童气管、支气管异物的诊断价值

目的　评价多层螺旋CT仿真支气管镜 (CTVB)对儿童气管、支气管异物的诊断价值。方法　对 12例临床高度怀疑气管、支气管异物的患儿行多层螺旋CT(MSCT)仿真支气管镜检查 ,自下咽部至膈面行轴位容积扫描 ,扫描后将容积数据传至GEAW 4 0工作站 ,运用Navigator功能软件获得CTVB图像 ,部分病例进行MPVR重建 ,结合CT原始图像进行诊断 ,并与纤维支气管镜检查对照。结果　 6例位于主支气管 ;2例位于气管 ,异物有花生米碎片 3例 ;玉米 2例 ;花生壳、黄豆及桃酥碎片各 1例 ;痰栓 4例。经纤维支气管镜取出异物或吸痰等治疗。结论　CTVB是一种非侵入性、无痛苦、安全、易为儿童所接受的检查方法 ,对儿童气管、支气管异物的诊断、术前筛选、定位、了解手术路径及术后复查等有很大的价值。     

歼(强)击机飞行员心脏瓣膜生理性返流调查分析

Objective To investigate the prevalence of physiological valvular regurgitation and its influence in fighter (attacker) pilots. Methods One hundred pilots were divided into high performance fighter pilot group (56 pilots) and common fighter pilot group (44 pilots). Their cardiac structure and function were examined by echocardiography. Results 55 pilots were diagnosed with physiological valvular regurgitation (55.00%), including 32 high performance fighter pilots (57.14%) and 23 common fighter pilots (52.27%). The prevalence of tricuspid, mitral and combined valvular regurgitation was 33. 00%, 9.00% and 13.00% respectively. There were 11 cases of mitral combined tricuspid valvular regurgitation, 1 case of tricuspid combined pulmonic valvular regurgitation and 1 ease of tricuspid combined aortic valvular regurgitation. In common fighter pilot group, right ventricular internal dimension (RVID) of the pilots with regurgitation was significantly higher than that of the pilots without regurgitation (t= 1.69, P＜0.05). No other significant differences were observed between groups (P＞0. 05). The cardiac structure and function of 100 pilots were in normal range. Conclusions High prevalence of physiological valvular regurgitation is found in fighter pilots, and in which tricuspid valvular regurgitation takes the highest. It is necessary to further investigate if the fighter pilot's specificity makes the different mechanism of physiological regurgitation from other eareer's and its long-term influence on pilot's cardiac structure and function.     

直升机应急医疗救治现状与发展

目的 综述国内外有关直升机应急医疗救护的发展情况. 资料来源与选择国内外该领域的相关文献. 资料引用引用国内外公开发表的文献资料36篇. 资料综合本文回顾了直升机医疗救护的历史及现状、直升机医疗救护的应用以及我国直升机医疗救护的发展情况,提出了对我国直升机医疗救护工作的发展建议. 结论 直升机应急医疗救护具有反应迅速、机动性强、受气候条件影响较小等优点而广泛应用于世界各国.直升机应急医疗救护为抢救人的生命尽可能地赢得时间,是适合现代医疗卫生的有效救治手段.中国在直升机应急医疗救护方面已取得长足进步,但与世界先进水平相比尚有很大距离,建立一支具有中国特色的直升机应急医疗救援体系十分必要. Abstract： Objective To review the domestic and abroad development of helicopter emergency medical service. Literature resource and selection Relevant articles published in China and abroad.Literature quotation Thirty-six published references were cited. Literature synthesis The paper reviewed the history and actuality of helicopter emergency medical service and its applications.The evolution in China was also reviewed and expected and the suggestions for future development were proposed. Conclusion Helicopter emergency medical service is being widely used in the world due to its advantages, such as rapid response, high flexibility, less weather influence, etc. It wins the furthest possibilities in saving people's life, and such effective rescue and cure concept is fitted to modern medication. China has made a remarkable progress in the development of helicopter emergency medical service but is still behind with the world's advanced stage. Building the system with Chinese characteristics would be the critical affair.     

后颅凹肿瘤的MRI诊断

笔者收集整理了 44例经手术病理证实的后颅凹肿瘤 ,比较ＣＴ和ＭＲＩ在后颅凹肿瘤的定位和定性诊断方面的价值 ,并分析后颅凹肿瘤的ＭＲＩ影像特点 ,现报告如下。1　资料和方法本组 44中男 2 1例 ,女 2 3例 ,年龄 7～ 84岁 ,平均 44 1岁。临床症状主要为头痛、头晕、视力减退、站立不稳、进食呛咳、四肢麻木、耳鸣、听力下降、耳聋等。 44例中 ,32例行ＣＴ平扫和增强扫描 ,44例均做ＭＲＩ检查 ,采用ＳＥ序列 ,Ｔ1 ＷＩ :ＴＲ/ＴＥ =560 /1 5ｍｓ ,Ｔ2 ＷＩ :ＴＲ/ＴＥ =40 0 0 /1 1 7ｍｓ,扫描层厚为 3～ 5ｍｍ ,横断面以Ｔ1 ＷＩ和Ｔ2 ＷＩ…