乙型肝炎、肝硬化患者生存质量评价及相关因素研究

目的测量并评价慢性乙型肝炎、肝硬化患者的生存质量（QOL）,以了解乙型肝炎、肝硬化患者生存质量状况,并探讨可能影响其生存质量的主要因素,为提高肝炎、肝硬化患者生存质量进行有效干预提供理论依据。方法采用SF-36量表,对50例慢性乙型肝炎、肝硬化患者和100例正常对照进行生存质量的测量与评价,并对生存质量的影响因素进行单因素分析和多因素逐步回归分析。结果与正常对照组相比,慢性乙型肝炎、肝硬化患者组的SF-36总评分及其八个纬度（躯体健康、躯体角色功能、躯体疼痛、总体健康、精力、社会功能、情绪角色功能、心理健康）的评分均降低,差异有统计学意义（P〈0．05）;影响慢性乙型肝炎肝硬化患者QOL的因素主要有经济收入、乏力、病程。结论乙型肝炎肝硬化患者的生存质量全面下降,影响慢性乙型肝炎肝硬化患者QOL的诸多因素中经济收入、乏力和病程是主要因素。     

乙型肝炎肝硬化患者生存质量及相关因素分析

目的了解乙型肝炎肝硬化患者的生存质量及相关因素,以寻找相应的提高患者生存质量的护理措施。方法以健康调查问卷对60例乙型肝炎肝硬化患者及健康对照组人群进行问卷调查,分析目标人群的生存质量,并对试验组完成疾病状况、人口学特点、个性及社会支持的调查,研究与其生存质量相关的因素。结果乙型肝炎肝硬化患者组的生存质量较正常对照组在总体生存质量及除外躯体疼痛的其他7个维度(躯体健康、躯体角色功能、总体健康、精力、社会功能、情绪角色功能和心理健康)均下降。社会支持、肝硬化分级、不适症状、情绪稳定性、病程、年龄、性别等因素与其生存质量相关。结论在制定护理计划的过程中,应特别关注生存质量得分低的患者,通过有效的护理措施来提高其生存质量。     

乙型肝炎、肝硬化患者生存质量与心理状况的相关性研究

目的了解乙肝、肝硬化患者的生存质量和心理状况,探讨两者之间的关系。方法对50例病例和100例对照进行生存质量测定量表(SF-36)、焦虑自评量表(SAS)和抑郁自评量表(SDS)测定,以评价病例和对照的生存质量和心理状况。将乙肝、肝硬化患者的生存质量与心理状况进行相关性分析,并用多因素逐步回归的方法研究心理状况与乙肝、肝硬化患者生存质量各纬度的关系。结果与正常对照组相比,乙肝、肝硬化患者的生存质量总评分以及各纬度(躯体健康、躯体角色功能、躯体疼痛、总体健康、活力、社会功能、情绪角色功能、心理健康)分值均降低;病例组的SAS总分和SDS总分均高于正常健康人群(P<0.05);乙肝、肝硬化患者焦虑、抑郁得分与其生存质量的各个纬度相关分析结果显示:乙肝、肝硬化患者焦虑程度与躯体角色功能、活力、情绪角色功能得分呈负相关;抑郁程度与躯体角色功能、总体健康、活力、情绪角色功能得分呈负相关,抑郁主要与社会功能和心理健康存在多元线形关系,焦虑主要与情绪角色功能有关。结论乙型肝炎、肝硬化患者的生存质量较正常人群低,患者的抑郁、焦虑情绪可能影响其生存质量。     

慢性乙型肝炎患者心理特点和生活质量分析

目的调查慢性乙型肝炎患者的心理特点和生活质量状况,为有针对性的进行心理干预提供依据。方法对184例慢性乙型肝炎患者(肝炎组)和190例正常体检健康人群(对照组)进行症状评定量表(SCL-90)和健康状况问卷(SF-36)量表测定。结果肝炎组SCL-90中总分、躯体化、人际关系、焦虑、抑郁、敌对因子分明显高于对照组,差别有统计学意义(P<0.05);肝炎组SF-36得分在维度躯体疼痛、活力、社会功能、情感角色、心理健康、总的健康状况等方面明显低于对照组,差别有统计学意义(P<0.05)。结论慢性乙型肝炎患者存在严重的心理问题,生活质量明显下降;对于慢性乙型肝炎患者应给予积极的针对性的心理干预。     

上海市浦东新区妊娠期妇女生命质量评价

目的　了解上海市浦东新区妊娠期妇女的生命质量状况.方法　应用健康调查简表(SF-36量表)对浦东新区妊娠期妇女进行生命质量评价,与浦东新区社区居民及年轻女性生命质量进行比较分析.结果　浦东新区妊娠期妇女生命质量8个维度的得分分别为生理功能68.05、生理角色限制42.54、躯体疼痛75.58、总体健康72.05、活力65.33、社会功能73.28、情感角色限制59.18、心理健康76.28,总评分为70.04.与浦东新区社区居民及年轻女性的生命质量比较,妊娠期妇女的生命质量较差.结论　妊娠期妇女的生命质量状况不容乐观,有关部门和社会应关注和提高妊娠期妇女生命质量.     

慢性乙型肝炎患者生存质量测量与影响因素分析

目的 测量并评价慢性乙型肝炎患者生存质量（QOL）,分析其主要影响因素。方法 采用生存质量SF－36表,对200例慢性乙型肝炎患者及200例正常对照进行生存质量（QOL）测量,并对QOL的影响因素进行单因素分析和多因素逐步回归分析,寻找其中主要影响因素。结果 慢性乙型肝炎患者组的SF－36总评分及生理机能、角色生理状况、心理健康状况、社会机能、机体活力、躯体不适和主观健康状部的平均评分与对照组相比显著降低（P＜0．01）;影响慢性乙肝患者QOL的主要因素是病程、并发症、谷丙转氨酶（ALT）、乏力、黄疸等。结论 慢性乙型肝炎患者的生存质量全面下降,有效的治疗以缩短病程、减少并发症及心理治疗和护理将有利于改善患者的生存质量。     

手法治疗前后对膝骨关节炎患者生存质量影响分析

目的:探讨手法治疗对膝骨关节炎患者生理功能、社会功能、躯体疼痛、活力、生理职能、精神健康、情感角色和总体健康的影响。方法:对120例KOA患者采用手法治疗,(2～3)日实施手法一次,治疗1个月后,根据SF-36量表的内容,对KOA患者治疗前后的生存质量进行评价。结果:治疗前后生理功能、社会功能、躯体疼痛、活力四个维度有明显改善(P<0.05);而生理职能、精神健康、情感角色和总体健康没有明显改善(P>005)。结论:手法治疗能明显改善KOA患者生存质量,是临床上一种治疗KOA有效、便捷的方法。     

慢性胃食管反流性咳嗽患者的生活质量评估

目的 研究慢性胃食管反流性咳嗽患者的生活质量。方法 根据胃食管反流性咳嗽(gastroesophageal reflux cough, GERC)诊断标准,将129例慢性咳嗽患者分为GERC组和非GERC组,另选48例健康者为正常对照组,记录各组性别、年龄、咳嗽病程,测量身高、体质量,计算体质量指数(body mass index, BMI),进行SF-36健康调查量表中生活质量8个维度总体健康、生理职能、情感职能、社交功能、生命活力、精神健康、生理功能、躯体疼痛评估,比较三组生活质量。结果 GERC组和非GERC组8个维度中的总体健康、生理职能、情感职能、社交功能、生命活力及精神健康均显著低于正常对照组(P<0.05),而生理功能、躯体疼痛和正常对照组比较,差异无统计学意义(P>0.05);GERC组和非GERC组的8个维度比较,差异均无统计学意义(P>0.05)。结论 慢性咳嗽患者生活质量差,GERC患者和非GERC患者生活质量无明显区别。     

唐山市区脑卒中患者生命质量调查

目的利用SF-36生命质量量表调查唐山市区脑卒中患者生命质量现状。方法采用整群抽样的方法,对抽取到的患者进行入户调查,利用t检验进行分析。结果唐山市区男性患者的生命质量在总体健康(GH)、精神健康(MH)维度男性评分要高于女性,但是在社会功能(SF)维度评分低于女性,在生理功能(PF)、生理职能(RP)、躯体疼痛(BP)、活力(VT)、情感职能(RE)维度评分两性之间没有差别。唐山市区脑卒中患者的生命质量低于四川省城市居民60岁以上组的评分参考值。结论唐山市区脑卒中患者生命质量总体评分较差。     

慢性乙型肝炎患者生存质量测量与影响因素分析

目的　测量并评价慢性乙型肝炎患者生存质量 (QOL) ,分析其主要影响因素。方法　采用生存质量SF 36表 ,对 2 0 0例慢性乙型肝炎患者及 2 0 0例正常对照进行生存质量 (QOL)测量 ,并对QOL的影响因素进行单因素分析和多因素逐步回归分析 ,寻找其中主要影响因素。结果　慢性乙型肝炎患者组的SF 36总评分及生理机能、角色生理状况、心理健康状况、社会机能、机体活力、躯体不适和主观健康状况的平均评分与对照组相比显著降低(P <0 .0 1) ;影响慢性乙肝患者QOL的主要因素是病程、并发症、谷丙转氨酶 (ALT)、乏力、黄疸等。结论　慢性乙型肝炎患者的生存质量全面下降 ,有效的治疗以缩短病程、减少并发症及心理治疗和护理将有利于改善患者的生存质量。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.