硫普罗宁治疗抗痨引起肝功能异常临床观察

目的　观察硫普罗宁治疗抗痨引起肝功能异常的有效性及安全性。方法　采用随机、对照试验方法 ,把适应证患者分为两组 :对照组 3 0例 ,用肝泰乐等护肝治疗 ;治疗组 3 0例 ,在对照组治疗的基础上静滴硫普罗宁 0 .3g/d ,两组疗程均为 15天。结果　治疗组和对照组对肝功能均有改善作用 ( P<0 .0 1) ,但治疗组与对照组比较有显著性差异 ( P <0 .0 5 ) ,不良反应发生率 6.67% ,仅有轻度皮肤反应 2例。结论　硫普罗宁对抗痨治疗所致肝功能损害有改善作用 ,安全性较好     

甘利欣、硫普罗宁联合应用对慢性肝炎的退黄作用

目的观察甘利欣、硫普罗宁联合应用对慢性肝炎的退黄作用。方法将70例慢性乙型肝炎患者随机分为治疗组38例,对照组32例。治疗组联合应用甘利欣、硫普罗宁,对照组应用强力宁、复方丹参,用药8周后对比观察血清胆红素的变化。结果治疗组显效率71.5%,总有效率为92.1%,均明显优于对照组(P<0.01)。结论甘利欣、硫普罗宁联合应用能提高退黄效果。     

硫普罗宁治疗原发性肝癌化疗栓塞术后肝损害的临床研究

目的 观察硫普罗宁对原发性肝癌化疗栓塞术后肝损害的治疗效果。方法 将50例原发性肝癌患者随机分为治疗组(n=25)和对照组(n=25)，两组均行肝动脉化疗栓塞术(TACE)，治疗组在术后应用硫普罗宁保肝治疗：硫普罗宁0.2静脉滴注，每日一次。治疗组则应用甘利欣保肝治疗：甘利欣200mg静脉滴注，每日一次。结果 治疗组比对照组肝功能损害明显减轻。结论 硫普罗宁对原发性肝癌化疗栓塞术后肝功能有良好的保护作用。     

甘利欣注射液联合硫普罗宁治疗中暑患者肝损害疗效评价

目的:观察甘利欣注射液联合硫普罗宁治疗中暑引起肝损害的疗效。方法:将46例中暑伴有肝损害的患者随机分成两组,硫普罗宁组(A组)和甘利欣注射液联合硫普罗宁组(B组),观察治疗前后患者临床症状改善情况及总胆红素、血清谷丙转氨酶、血清谷草转氨酶等指标的变化。结果:应用甘利欣注射液联合硫普罗宁治疗中暑引起的肝损害总有效率为87.0%,硫普罗宁组总有效率为60.9%,两组患者总有效率差异有显著性(P<0.05)。结论:甘利欣注射液联合硫普罗宁治疗中暑引起的肝损害,临床上具有较好的疗效。     

灯盏花注射液治疗慢性肝炎临床观察

目的 :观察灯盏花注射液治疗慢性肝炎临床疗效。方法 5 0例慢性乙肝病人随机分为治疗组 ( 2 5例 ) ,对照组( 2 5例 )。治疗组用灯盏花注射液及甘利欣、极化液 ,对照组用甘利欣及极化液。分别与治疗前、治疗两周、治疗四周时观察临床症状、体症及肝功能变化。结果 :治疗组临床症状、体症、肝功能的变化明显优与对照组 (P <0 .0 5 )。结论 :灯盏花注射液在保肝治疗中具有良好的作用。     

还原型谷胱甘肽联合硫普罗宁治疗乙醇性肝病疗效观察

目的:评价还原型谷胱甘肽联合硫普罗宁方案治疗酒精性肝病的临床疗效。方法:将78例患者随机分为治疗组(n=39)和对照组(n=39)。两组患者均戒酒及含酒精的饮料,进高蛋白饮食,补充各种维生素。对照组给予门冬氨酸钾镁静脉滴注;治疗组在对照组的基础上使用还原型谷胱甘肽联合硫普罗宁进行治疗,两组均治疗2～3周。结果:治疗组治疗后各血生化指标值显著小于治疗前,也显著小于对照组治疗后的值,差异有统计学意义(P<0.05)。治疗组总有效率为89.74%,对照组总有效率为71.79%,治疗组显著高于对照组,差异有统计学意义(P=0.016,<0.05)。结论:还原型谷胱甘肽联合硫普罗宁方案治疗酒精性肝病疗效显著,无不良反应,值得临床推广。     

硫普罗宁联合阿德福韦酯治疗慢性乙型肝炎疗效观察

目的 探讨硫普罗.宁联合阿德福韦酯治疗慢性乙型肝炎疗效观察.方法 90例慢性乙肝患者,治疗组患者用硫普罗宁(河南新谊医药集团提供)200mg,加入5%葡萄糖注射液250ml中静脉点滴,1次/d,疗程10～20d.对照组采用一般护肝治疗(甘利欣、门冬氨酸钾镁、肌苷等).观察两组患者肝功能及肝纤维化指标(HA、PⅢP、LN、Ⅳ-C)等.结果 治疗组疗效明显优于对照组.两组疗效差异有显著性意义.结论 硫普罗宁联合阿德福韦酯治疗慢性乙型肝炎疗效显著.     

复方丹参与硫普罗宁抗肝纤维化的临床研究

[目的 ]观察复方丹参、硫普罗宁单用及合用对肝纤维化的影响。 [方法 ]复方丹参 +硫普罗宁治疗组、复方丹参治疗组、硫普罗宁治疗组各 4 0例 ,分别静滴复方丹参 2 0ml和 /或硫普罗宁 0 2g ,qd ,共 8周。对照组 30例 ,予一般护肝治疗。[结果 ]各组治疗后肝功能、肝纤维化指标均有不同程度好转 ,含丹参治疗组肝纤维化指标好转与硫普罗宁组及对照组比较差异显著 (P <0 0 5 ) ,且联合用药组优于单用组。 [结论 ]复方丹参与硫普罗宁均有抗肝纤维化的作用 ,且两者合用能提高抗肝纤维化的效应。     

硫普罗宁联合阿拓莫兰治疗药物性肝炎临床观察

目的观察应用硫普罗宁联合阿拓莫兰治疗药物性肝炎的临床疗效.方法将98例药物性肝炎患者随机分为对照组和治疗组.对照组给予甘利欣、门冬氨酸钾镁、肝泰乐等护肝治疗,治疗组在对照组基础上另加硫普罗宁和阿拓莫兰,疗程均为4周,观察临床症状、体征及肝功能等方面的变化.结果治疗组在症状、体征、肝功能等方面均优于对照组.结论硫普罗宁联合阿拓莫兰治疗药物性肝炎较一般护肝治疗效果好.     

硫普罗宁治疗酒精性肝病的疗效观察

目的:观察硫普罗宁治疗酒精性肝病的临床疗效。方法:将56例酒精性肝病患者随机分为两组,治疗组28例,用硫普罗宁治疗;对照组28例,用甘利欣治疗。结果:治疗后,治疗组较对照组AST、ALT、GGT、TBIL改善较明显,且差异显著(P<0.05)。结论:硫普罗宁可明显改善酒精性肝病患者肝功能,提高肝脏储备能力。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.