大数据环境下医学信息学教育的变革与发展

从医学信息学教育的新目标、新内容、新准则、新挑战等角度探讨了大数据环境下医学信息学教育的变革,从资源观念、教学模式、教育决策、培养方案等角度探讨了大数据环境下医学信息学教育的发展,以期引发大数据时代对于医学信息学教育的思考。     

医学信息教育的中国特色与国际化趋势

从医学信息教育的中国特色、医学信息教育的国际化趋势、实现医学信息教育国际化的有效途径三个方面对当前我国医学信息教育发展方向进行了分析,提出以下三个学术观点:(1)中国的医学信息教育发源于医学图书情报等多个学科或专业领域,表现为“学科群”、“专业群”以及由此必然形成的带有典型交叉学科特征的“专家群”的学科特征,具有明显的中国特色;(2)要把握国际医学信息学的发展趋势,跟踪研究前沿和最新进展,了解国际医学信息学教育的总体发展趋势和变革现状,顺应医学信息学的学科发展和医药卫生领域需求,在保持和发展中国特色的同时,开拓国际视野,实现新的跨越;(3)在国际医学信息学教育发展的平台上思考医学信息学人才培养目标、课程体系、培养模式、教学方法,推进医学信息教育、教学改革与创新,加速实现我国医学信息学教育与国际接轨.     

从我国医药企业医学信息专员职位看我国医学信息学教育现状

介绍了我国医药企业医学信息专员的职能设置、技能要求、企业和地域分布等特点,结合我国医学信息学人才培养的现状,分析了我国医学信息学教育中医学课程学时数较少、专业定位不明确等问题,提出了对我国医学信息学教育方向的思考和建议。     

中美医学信息学教育的比较研究

本文阐述了中美医学信息学教育的发展概况，通过对中关医学信息学教育的模式和课程设置等方面的比较分析，提出了改革教学体制，改进教学模式，拓宽学科知识范畴，加强基础理论研究，培养高层次医学信息专业人才等发展我国医学信息学教育的建议。     

中欧医学信息学教学对比研究

从课程设置、师资力量、研究方向3个方面对中国和欧洲医学信息学教育的现状和模式进行比较分析,探讨中国和欧洲医学信息教育存在的差异。吸取欧洲国家医学信息学的教学经验,对我国医学信息学进行教学体制改革,教学内容创新,推动我国医学信息学教学的发展。     

基于GMDS倡议的医学信息学教育课程体系的构建

分析和总结了德国医学信息学、生物测量和流行病学协会（GMDS）倡议的医学信息学本科课程体系,结合我国医学信息学教育的课程体系设置的现状,提出了构建医学信息学本科课程体系的五原则：特色性、整体性、科学性、实用性、针对性,并以中南大学医药信息系的课程体系为基础,提出了新课程设置方案,以培养社会需要的医学信息学复合型人才,实现医学信息学的长足健康发展。     

我国医学信息学教育现状及思考

为了促进我国医学信息学教育的发展,文章对我国医学信息学教育的起源、教学层次、学位授予、培养模式、课程设置和师资等方面的现状进行了分析,并且比较了国内与国外的医学信息学教育,提出了加强教育地位、调整课程设置、提高培养层次、加强国际交流、拓宽师资来源等建议。     

推动医学信息学在中国发展的关键

医学信息学是一门新兴的多学科交叉科学，它是医院信息管理系统应用领域的理论和学科基础。本文对比了国内外医学信息学的发展现状，指出了中外关于“医学信息学”概念理解的差异，并指出大力发展和普及医学信息学的教育是促使医学信息学在我国发展走向正规化和国际化的关键。     

美国医学信息学教育现状分析及启示

本文介绍了美国医学信息学教育的基本情况，并从教学层次、学位授予、课程设置、科研及师资等方面对美国近20所医学信息学教育机构进行分析和整理，以期从中得到某些启示，推动我国医学信息学教育的发展。     

北美iSchools教育及其对我国医学信息学教育的启示

探讨北美iSchools的发展现状及教育模式,分析我国医学信息学教育现状,力求将iSchools引入到我国医学信息学教育中,从学科定位、人才培养、交流与合作等方面为我国医学信息学教育的科学持续发展提供依据.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…