浅谈现代临床药学的发展及研究

目的 浅谈我国现在临床药学,总结临床药学的发展及研究.方法 通过多年实际工作经验对比国内临床药学工作人员,取其长,补其短.结合实际工作环境,提了一些改革措施.结果 作为国内医院药学工作之重,临床药物学工作的改进已成为重中之重.结论 作为临床药学工作人员应广泛吸收外来知识,为临床药学工作的改革进微薄之力.     

加强物理化学与药学融合的教改方法探讨

物理化学作为药学专业基础课,与药学专业课和药学研究关系密切,为了加强物理化学与药学的融合,在教学改革过程中通过改革教学内容、开设开放性实验、设立专题讲座三方面提出了一些见解。     

浅析我国医院药学的发展趋势

随着医疗体制改革的深入,医院实行医药分家已势在必行。作为一名药学工作者,对未来医院药学的发展应具有一定的前瞻性。重点对不同历史时期国内外医院药学模式转变进程的比较,展望未来医院药学的发展前景与人才需求,促进医院药学的不断前进,为未来医院药学的发展做出自己的贡献。     

药学专业《物理化学》教学方法改革的探索与实践

《物理化学》作为药学专业基础课,与药学专业课和药学研究关系密切。通过加强理论知识与实际应用,特别是药学实践的联系和融合,不断推进教学方法改革,以激发学生的学习兴趣,提高教学质量。     

药学计量特色新专业的班主任工作

中国计量学院药学计量特色专业为新办专业,主要培养具有扎实药学基础、较强药学计量能力的新型人才为目标,服务于国家医药质量振兴事业。但作为新办专业,在人才培养过程中会遇到诸多问题,班主任作为教育活动的主要参与者,要深入领会药学计量特色专业的内涵,在人才培养活动中开拓性地开展工作。本文就班主任在药学计量特色专业教育活动中的工作谈几点看法。     

探究对肿瘤患者实施中药药学服务的可行性

随着医疗服务水平的不断提高以及药学技术的发展,医院加强药学服务可保障合理用药、提高用药安全性。中药药学服务作为药学服务的分支,是药学服务的重要内容,其以中医药理为依据,通过明确中药四气、五味、归经与中医辨证之间的关系,以提高用药合理性、安全性及有效性[1]。中药治疗作为缓解肿瘤症状、抑制肿瘤复发的有效手段,合理运用有助于延长患者生存时间,提高生存质量,而中药药学服务是保证用药质量的关键所在,加强中药药学服务可全面提升就医质量[2]。     

临床药学专业药学文献检索课程教学探索与实践

药学文献检索作为临床药学专业一门重要的专业必修课,其教学质量直接影响学生的科研素养和后续毕业论文的质量。根据我校临床药学专业的培养目标和教学特点,通过整合课程体系,优化教学方案和内容,调动学生学习的积极性和主动性,提高临床药学专业药学文献检索课程的教学效果。     

高职药学教育应适应社会发展

高职药学教育的目标是培养适应社会发展的医药人才。随着经济和社会的发展以及药学的发展,药学的传统观念、药师的职能与工作模式正在发生转变,作为与市场经济密切联系的高职药学教育则相对滞后。为改变这一现状,应对目前的高职药学教育进行改革。     

论药学职业道德在药房工作中的意义

药学职业涉及广大人民群众的生命健康及生存质量。药学职业道德作为一种特殊的职业道德,除了具有一般职业道德的特点之外,还要求药学工作人员具有扎实的药学知识与技能,以及对社会、对公众、对患者健康高度的责任感和献身精神。本文结合多年工作实践,阐述和分析药学职业道德在药学窗口服务中的重要性,外在树立形象标杆,内在提升业务技术水准,完善药学工作,提供优质服务。     

分析药学心理学在药学保健中的应用

药学心理学是以药学、心理学作为基本理论的一门学科,是通过非药物自身信息对患者进行刺激,以获得治疗效果的学科.通过将药学管理与疾病诊断、临床治疗结合在一起,不仅可以提高药学技术的服务质量,也可以提高医院的医疗服务质量.本文对药学保健过程中药学心理学的应用进行了综述,以不断提高药学心理学的重视程度,更好地为患者服务.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…