第3例中国数字化可视人体数据集报告

目的　建立更为细致的中国数字化可视人体数据集。方法　选择经肉眼观察、CT和MRI检查无器质性病变的中等身材、青年男性人体标本 1例 ,经外形测量、血管灌注后 ,用 5 %明胶包埋 ,置入 -3 0℃冰库中冰冻 1周 ,然后在 -2 5℃低温实验室中用TK 63 5 0型数控铣床 (铣切精度为 0 .0 0 1mm)从头至足逐层铣切。逐层用高清晰度数码相机摄影 ,完成人体模型数据获取 ,得到人体结构数据集。结果　所选用标本为男性 ,2 1岁 ,身高 182 0mm ,体质量 66kg ,非器质性疾病死亡。CT扫描层厚 :头颈部为 1.0mm ,其他部位为 2 .0mm。MRI扫描层厚头颈部为 1.5mm ,其他部位为 3 .0mm。连续横断面层厚 :全身均为 0 .1mm ,全身共计 183 98个断面。数字化摄影分辨率为 10 9890 5 6( 4 0 64× 2 70 4)像素 ,每个断面图像文件大小为 62 .9MB ,整个数据集数据量为 115 7.2 3GB。其研究结果同时在国际互联网站发布 ,网址为 :http : www .chi nesevisiblehuman .com 。结论　①经文献检索 ,目前全世界已经报道的可视化人体数据集全身切片最薄为 0 .2mm (本研究组报道的首例中国数字化可视人体颅底部局部切片达到 0 .1mm) ,切片数均为数千个断面 ,断面摄影分辨率均为数百万像素 ,数据量为数十个GB ,或一百多个GB ;本研究完成的数据集全     

首例中国女性数字化可视人体数据集采集与可视化研究

目的　建立中国女性数字化可视人体 (Chinesedigitizedvisiblehumanfemale)。方法　选择经肉眼观察、CT和MRI检查无器质性病变的中等身材、青年女性人体标本 1例 ,经外形测量、血管灌注后 ,用 5 %明胶包埋 ,置入 -3 0℃冰库中冰冻 1周 ,然后在 -2 5℃低温实验室中用TK 63 5 0型数控铣床 (铣切精度为 0 0 0 1mm)从头至足逐层铣切。逐层用高清晰度数码相机摄影 ,完成人体模型数据获取 ,得到人体结构数据集。利用连续断层图像数据 ,在SGI图像工作站上 ,利用本课题组自主开发的三维重建软件包进行人体结构的三维重建和立体显示。结果　所选用标本为女性 ,2 2岁 ,身高 162 0mm ,体质量 5 4kg ,非器质性疾病死亡。CT扫描层厚 :头颈部为 1 0mm ,其他部位为 2 0mm。MRI扫描层厚头部为 1 5mm ,其余部位为 3 0mm。连续横断面层厚 :头部为 0 2 5mm ,其他部位为 0 5mm ,全身共计 3 64 0个断面。数字化摄影分辨率为 62 914 5 6(3 0 72× 2 0 48)像素 ,每个断面图像文件大小为 3 6MB ,整个数据集数据量为 13 1 0 4GB。结论　①经文献检索和查新 ,仅见美国Colorado大学于 1995年 12月完成了 1例女性人体标本的数据采集。本研究结果增添了新的一例女性可视化人体的数据资料 ,其研究结果同时在国际互联网站发布 ,网     

首例中国可视化人体心脏薄层断层解剖学研究

目的　探讨人体心脏薄层影像断面的形态学规律。方法　经肉眼观察和CT、MRI检查无器质性病变的中等身材、中年男性标本 1例 ,经外形测量、血管灌注后 ,用明胶包埋 ,冰冻 1周 ,然后在低温实验室中用数控铣床从头至足逐层洗切。逐层用高清晰度数码相机摄影 ,完成人体数据集的获取。结果　首例中国可视化人体心脏部分共计 15 0层 ,每层厚度为 1 0mm ,每层断面所显示的心脏结构清晰 ,数字化摄影分辨率为 62 914 5 6( 3 0 72× 2 0 48)像素 ,每个断面图像文件大小为 3 6MB ,整个心脏部分数据集量为 2 7GB。并对本例可视化人体心脏部分的数据集进行总结和分析。结论　本研究报道的首例中国可视化人体心脏部分为连续、完整的薄层断面 ,无节段性数据缺损 ,厚度均匀 ,为心脏三维重建及可视化心脏的研制奠定了基础 ,也为临床影像诊断学 (超声、CT、MRI)提供了完整、连续的薄层断层解剖学资料     

首例中国女性数字化可视人体数据集完成

本课题组继 2 0 0 2年 8月完成首例数字化可视人体之后[1 ] ,于 2 0 0 3年 2月完成了一例女性数字化可视人体数据集的建立。　　材料与方法　选择经肉眼观察、ＣＴ和ＭＲＩ检查无器质性病变的中等身材、青年女性人体标本 1例 ,经外形测量、血管灌注后 ,用 5 %明胶包埋 ,置入 -3 0℃冰库中冰冻 1周 ,然后在 -2 5℃低温实验室中用ＴＫ 63 5 0型数控铣床 (铣切精度为 0 0 0 1ｍｍ)从头至足逐层铣切。逐层用高清晰度数码相机摄影 ,完成人体模型数据获取 ,得到人体结构数据集。利用连续断层图像数据 ,在ＳＧＩ图像工作站上 ,利用本课题组自主开…     

游离肝脏可视化数据获取技术研究

目的建立获取可供计算机可自动识别与三维重建的高精度人体游离肝脏可视化数据集的技术.方法采用多管道搭配灌注法对游离肝脏肝内管道进行分色灌注填充,经数控机床逐层铣切,完成断面图像数码摄影.结果获取无缺损的连续薄层横、冠、矢状断面可视化肝脏图像数据集,断面图像分辨率为1 100万像素,断面厚度0.2 mm.结论经多管道分色灌注后铣切获取的薄层肝脏断面图像能够较好地展示肝内管道系统的断面解剖学数据,有利于计算机准确而快捷地识别与完成肝内管道系统的三维重建.     

虚拟人体研究进展

目的概述虚拟人体的研究进展。方法通过国内外文献的检索,对虚拟人体的研究进行分析、归纳、概括。结果虚拟人体的研究主要是通过尸体标本铣切采集的人体数据集进行三维重建或利用CT、MRI进行三维重建。结论随着虚拟人体的深入研究,已在临床医学、医学教育和其它科研领域得到广泛应用。     

重金属氧化物应用于CT成像进行人体血管3D可视化重建

目的:探索应用重金属氧化物填充剂对人体标本血管进行灌注,经CT扫描后进行血管3D可视化重建。方法:采用金属氧化物粉末(氧化铅、氧化铋、氧化铈)与填充载体配制成填充剂进行新鲜尸体血管灌注,X线摄影,CT扫描获得数据集,采用Mimics10.01或3d-Doctor软件进行血管三维重建。结果:金属氧化物造影填充剂灌注的血管标本,X线摄影下标本动脉血管显影清晰,细小血管也充分显示;CT连续扫描断面图像血管显影均匀,三维重建所得图像清晰,管道饱满,边缘连续平滑,无齿状伪影,立体感强。结论:重金属氧化物是一种理想的人体标本管道造影材料,适用于人体血管3D可视化重建。     

可视化人体肝脏技术概述

可视化人体肝脏是利用人体肝脏数据集或肝脏CT、MRI数据三维重建获得的计算机肝脏模型,对肝脏解剖学教学、肝脏疾病的诊断、肝脏外科的发展有重要的意义.本文在阅读大量文献的基础上,重点概述可视化人体肝脏的方法、步骤、技术和可视化人体肝脏目前研究的概况.     

首例中国可视化人体心脏三维重建及临床意义

目的 对首例中国数字化可视人体的心脏进行三维重建，为心脏疾病的影像学诊断和外科手术提供三维解剖学依据。方法 将首例中国数字化可视人体心脏部分的薄层断面(层厚1．0mm)输入SGI工作站，经数据分割、对位重建、平滑处理和三维显示等步骤，完成对心脏结构的三维重建。结果 本研究完整地重建出了心脏结构，重建的结构能够以多结构、多彩色实体模型方式显示，可显示心脏内部各结构的空间位置和毗邻关系，可在三维空间伴置上绕任意轴旋转任意角度。结论 重建出的三维图像清晰地显示了心脏内部和整体的结构，实现了心脏的二维可视化。     

首例中国可视化人体头颈部CT影像三维重建的初步研究

目的 对首例中国可视化人体头颈部CT影像进行二维重建研究。方法 将首例中国可视化人体头预部的轴位断层CT图像(层厚1mm，连续扫描)，应用Siemens CRT3.0图像处理软件在SGI Graphies计算机工作站上进行三维重建和观察。结果 头面部结构得到良好重建，其面部轮廓包括鼻翼、唇．外耳廓．下颏等均能清晰显示。头颈部骨骼的精细三维重建，显示出颅底圆孔、卵圆孔、棘孔等细微结构。头颈部三维剖面观察可使包括垂体、脑干、颈髓、蝶窦、鼻咽等结构获得良好显示。结论 本研究实现了对首例中国可视化人体头颈部CT影像的三维重建和可视化，为深入进行头颈部解剖结构的三维可视化研究及解剖学和影像学的比较研究奠定形态学基础。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.