美罗培南治疗重症肺炎的效果

目的:研究美罗培南治疗重症肺炎的临床效果。方法:对自2014年12月至2015年11月间在我院的71例重症肺炎患者采用美罗培南进行治疗研究,并对患者治疗的评价指标进行统计分析。结果:71例患者的总有效率为85.92%,死亡率为2.82%,治疗前后的临床指标发生显著改善,比较差异值P0.05,具有统计学意义。结论:在治疗重症肺炎时采用美罗培南具有较好的治疗有效率,并可明显改善患者的临床指标,值得临床推广应用。     

分析对重症肺炎患者采用美罗培南不同静脉输注方式进行治疗的效果

目的分析对重症肺炎患者采用美罗培南不同静脉输注方式进行治疗的效果。方法随机分为两组,即对照组和观察组,比较采用美罗培南不同静脉输注方式的对照组和观察组患者在临床疗效、细菌学疗效以及其他指标上的不同,探究效果更好的美罗培南的静脉输注方式。结果观察组临床疗效比对照组好,在细菌学疗效以及其他指标上也比对照组占有优势,差异明显,具有统计学意义(P0.05)。结论在重症肺炎患者的治疗中美罗培南的静脉输注方式设定为持续泵入输注方式是可行的,更适宜被应用和推广。     

美罗培南持续泵入治疗ICU呼吸机相关性肺炎的效果观察

目的观察美罗培南持续泵入治疗ICU呼吸机相关性肺炎的效果。方法选取2010年2月至2017年2月的ICU呼吸机相关性肺炎的患者18例作为研究对象,采用随机分组法对其进行分组,平均分为实验组与对照组,每组各9例患者,对实验组患者采用美罗培南持续泵入治疗的方式进行治疗,对对照组患者采用美罗培南间断性泵注进行治疗,对两组患者的治疗效果进行观察。结果实验组患者的治疗效果明显优于对照组,且实验组患者产生的花费及住院时长都明显优于对照组,差异明显,具有统计学意义(P0.05)。结论采用美罗培南持续泵入方式对患者进行治疗,能够提升治疗的有效性,减少患者的经济投入,具有显著的应用意义。     

重症肺炎患者应用美罗培南对临床疗效、血清CRP及降钙素原的效果影响

目的:分析重症肺炎患者应用美罗培南对临床疗效、血清C反应蛋白(CRP)及降钙素原(PCT)的效果影响.方法:选择该院2014年8月至2016年8月收治的86例重症肺炎患者作为本次的研究对象,分为每组均占据43例的常规组与实验组,其中对常规组患者采取哌拉西林他唑巴坦进行治疗,对实验组采取美罗培南进行治疗,对比两组治疗效果.结果:实验组与常规组的治疗总有效率分别为95.35％与76.74％(P＜0.05);治疗后实验组血清CRP与PCT下降幅度明显优于常规组(P＜0.05);实验组与常规组的不良反应发生率分别为9.30％与6.98％ (P＞0.05).结论:对重症肺炎患者采用美罗培南进行治疗的临床疗效显著,药物安全有效,可明显改善其血清C RP、PCT水平,值得实践推广.     

COPD合并感染性肺炎患者联合应用美罗培南与莫西沙星的疗效及不良反应分析

目的:分析探索美罗培南联合莫西沙星治疗慢性阻塞性肺疾病合并感染性肺炎的临床效果及不良反应。方法:将84例慢性阻塞性肺疾病合并感染性肺炎患者作为观察对象,将其随机分成研究组和对照组,每组各42例。对照组采用左氧氟沙星治疗,研究组采用美罗培南联合莫西沙星治疗,在连续治疗1周后比较两组患者治疗效果、症状消失时间及不良反应的发生情况。结果:经过1周的治疗后,联合治疗的研究组治疗总有效率(97.62%)显著优于使用左氧氟沙星治疗的对照组(总有效率82.93%)(P<0.05);研究组患者的症状消失时间明显少于对照组(P<0.05);研究组患者不良反应发生率仅为9.52%,明显低于对照组发生率23.81%(P<0.05)。结论:美罗培南联合莫西沙星治疗慢性阻塞性肺疾病合并感染性肺炎有很好的临床治疗效果,且不良反应少,安全性高,值得在临床上大力推广使用。     

喜炎平注射液对美罗培南治疗铜绿假单胞菌肺部感染的增效观察

目的观察喜炎平注射液对美罗培南治疗铜绿假单胞菌肺部感染的增效作用。方法回顾性调查128例确诊为铜绿假单胞菌肺部感染的住院患者,对照组为美罗培南组,试验组为喜炎平注射液联合美罗培南组,两组各64例,观察两组的临床疗效、症状(体温、咳嗽、咳痰)缓解时间、实验室指标(WBC、影像学)恢复时间、细菌学效果和不良反应发生率。结果试验组临床疗效优于对照组(P0.05);治疗后两组患者症状(体温、咳嗽、咳痰)及实验室指标(WBC、影像学)改善时间比较,试验组均较对照组短,差异有统计学意义(P0.01);两组细菌学效果及不良反应发生率比较差异无统计学意义(P0.05)。结论喜炎平注射液对美罗培南治疗铜绿假单胞菌肺部感染有增效作用。     

美罗培南治疗老年卒中相关性肺炎的临床效果观察

目的:探究美罗培南治疗老年卒中相关性肺炎的临床效果。方法:选择2014年3月-2015年3月来我院就诊的106例老年卒中相关性肺炎患者为研究对象,将其分成两组,均以常规治疗为基础,对照组使用头孢他啶联合生理盐水治疗,观察组使用美罗培南联合生理盐水进行治疗,7d后观察咳嗽好转时长,退烧时长,湿罗音消失时间,白细胞系数恢复正常时间和平均住院时长,同时对两组患者在治疗期间发生的副反应情况进行全面记录。结果:两组患者治疗期间不良反应不存在统计学意义,P0.05.和对照组相比,观察组患者在咳嗽好转时间,退烧时间,白细胞计数正常时间和湿罗音消失时长方面均较好,组间数据存在统计学意义,P0.05。结论:对于老年卒中相关性肺炎疾病,以常规治疗为基础,为患者使用美罗培南,可减少住院时长,全面改善患者临床体征。不良反应少,安全性强,值得进一步在临床治疗中推广使用。     

抗生素降阶梯疗法治疗老年重症肺炎的疗效分析

目的：观察抗生素降阶梯疗法在老年重症肺炎治疗中的临床疗效,探讨老年重症肺炎抗生素应用的治疗效果。方法资料随机选择2012年5月—2013年5月本院收治的老年重症肺炎患者120例,按照治疗方法随机平均分为研究组（n＝60）与对照组（n＝60）,研究组患者予以抗生素降阶梯治疗,对照组患者予以传统的抗生素治疗,观察并比较两组患者治疗的有效率,感染控制时间、住院时间等指标的差异。结果研究组患者治疗有效率为96．66％,对照组患者治疗有效率为72．03％,两组患者治疗有效率比较,差异有统计学意义（ P＜0．05）;研究组患者临床治疗住院时间、平均机械通气（ MV）时间以及感染的控制时间均明显优于对照组,差异有统计学意义（ P＜0．05）。结论应用抗生素降阶梯疗法对老年重症肺炎患者进行治疗的临床疗效显著,可有效地控制老年患者病情。     

美罗培南不同静脉输注方式治疗重症肺炎的临床疗效观察

目的评价美罗培南不同输注方式治疗重症肺炎的临床疗效及经济学效应。方法选取ICU重症肺炎患者80例,随机分为传统输注组和持续泵入组。传统输注组的输注方案为美罗培南1 g/次溶于0.9%生理盐水250 ml中,每8 h 1次,配制成静脉点滴注射液,经15-30 min静脉点滴给药;持续泵入输注组的输注方案为美罗培南3 g/次溶于0.9%生理盐水50 ml中,每24 h 1次,配制成静脉点滴注射液,使用微量推注泵每次持续推注24 h。比较两组患者的临床疗效、病原学疗效,并对两组患者抗生素药物经济支出进行评估。结果两组患者的临床疗效、病原学疗效比较,持续泵入组均优于传统输注组(P<0.05);持续泵入组疗程缩短,并且抗生素药物经济支出少于传统治疗组(P<0.05)。结论使用美罗培南持续泵入输注方案治疗重症肺炎的疗效较传统输注方案更佳,并且缩短抗生素药物应用疗程,减少医药费用支出。     

抗生素相关性肠道菌群失调的现状调查

目的 :了解我院菌群失调与抗生素应用情况 ,以增强医护人员合理使用抗生素意识。方法 :采用粪便直接涂片染色法诊断有无菌群失调及菌群失调的程度 ,并采用前瞻性和回顾性相结合的方法 ,调查抗生素应用情况。结果 :老年患者发病率较高 ,抗生素相关性菌群失调的发病率为 6 5 .0 % ,引起菌群失调的药物种类多样化 ,主要是头孢菌素、亚胺培南、青霉素、哌拉西林、克林霉素。结论 :对特殊人群使用抗生素时 ,有必要进行肠道菌群的监测 ,以促进抗生素的合理应用。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.