运用E-Tracking技术检测酒精性肝病患者戒酒治疗前后颈动脉弹性变化的研究

目的 运用E-Tracking技术检测酒精性肝病(ALD)患者戒酒治疗前后颈动脉弹性的变化.方法 ALD患者137例,戒酒组31例,戒酒失败组106例,常规颈动脉超声获取治疗前后IMT、D、RI、PI、S/D几项指标,运用E-Tracking技术获取治疗前后Eρ、β、AC、AI、PWVβ指标.比较两组治疗前后常规超声指标及E-Tracking指标;比较戒酒组中,不同程度肝损伤的各类在戒酒治疗前后E-Tracking指标.结果 戒酒组与戒酒失败组治疗前后常规超声指标无明显差异,戒酒组治疗后Eρ、β、PWVβ较治疗前减低,AC增高,差异有统计学意义(P＜ 0.05或P＜ 0.01),戒酒失败组各项参数差异无统计学意义;戒酒组中,酒精性脂肪肝(AFL)及酒精性肝炎(AH)患者E-Tracking指标较酒精性肝硬化(AC)患者变化显著.结论 ALD患者戒酒治疗后颈动脉硬度、弹性减低、顺应性增高、扩张性降低,尤以酒精性脂肪肝及酒精性肝炎患者更为明显,E-Tracking技术能准确定量评价颈动脉弹性,为临床评价ALD治疗效果提供了一种新的方法.     

应用新版E-Tracking技术对高血压患者颈动脉血管病变的研究

目的：应用新版血管壁回声跟踪技术（E-Tracking）评价高血压颈动脉血管病变。方法：分别对高血压患者56例（平均年龄55.5岁）和正常健康者52例（平均年龄54.7岁）采用高频线阵探头测量颈总动脉内中膜厚度（IMT），应用新版血管壁回声跟踪技术检测弹性系数（Eρ）、硬化参数（β）、顺应性（AC）、脉搏波传导速度（PWVβ）和增大指数（AI），并对高血压患者组上述参数进行相关性分析。结果：高血压组较正常对照组Eρ，β，PWVβ及IMT增高，AC降低，且均有显著性差异。高血压组的PWVβ与β，Eρ和IMT呈正相关，与AC呈负相关；高血压组的AI与Eρ，β，AC和IMT无明显相关。结论：新版E-Tracking技术客观准确的反映了高血压患者血管弹性改变，是评价血管壁弹性简便实用的新方法。     

血管回声跟踪技术评价冠心病患者颈动脉弹性与肱动脉内皮功能的相关性

目的探讨颈动脉弹性参数与肱动脉内皮功能的相关性。方法冠心病组、冠状动脉粥样硬化组、健康对照组各30例,回声跟踪技术检测颈动脉弹性参数：压力应变弹性系数（Ep）、硬化参数（β）、顺应性（AC）、脉搏波传导速度（PWVβ）和增大指数（AI）;肱动脉袖带加压检测血流介导的内皮依赖性血管舒张功能（FMD）。结果冠心病、冠状动脉粥样硬化患者Ep、β、PWVβ均较对照组增高,AC、FMD减低（P〈0．01）;所有受试者、冠心病组、冠状动脉粥样硬化组、对照组的FMD分别与Ep、β、PWVβ呈负相关,与AC呈正相关,与AI无相关性。结论颈动脉弹性各参数与肱动脉内皮功能呈高度相关,提示回声跟踪技术能早期、定量反映冠心病患者血管的改变,是评价血管内皮功能简便实用的方法。     

血管回声跟踪技术评价头颈部肿瘤患者放疗后颈动脉弹性

目的:应用E-Tracking技术探讨头颈部肿瘤患者放疗后颈动脉弹性功能变化及其临床意义.方法:收集75例放疗后头颈部肿瘤患者(放疗组)及65例健康志愿者(对照组),比较两组颈动脉的参数变化;选择放疗组39例患者比较放疗前与放疗后的颈动脉参数变化;E-Tracking参数包括僵硬度(β)、弹性模型(Eρ)、顺应性(AC)、脉搏波传导速度(PWVβ)及内-中膜厚度(IMT).并对放疗组颈动脉损伤影响因素进行分析.结果:放疗组较对照组β、Eρ、PWVβ、IMT升高,AC降低,差异均有统计学意义(P＜0.05).与放疗前比较,放疗后β、Eρ、PWVβ值增高,AC降低,差异有显著性(P＜0.05),IMT比较无显著性差异(P＞0.05).经多因素Logistic回归分析发现年龄＞60岁、放疗间隔时间＞5年是头颈部肿瘤患者放疗后颈动脉损伤的危险因素.结论:头颈部肿瘤患者放疗后颈动脉弹性功能较正常人减低;E-Tracking参数能够早期反映颈动脉弹性功能的异常改变;年龄、放疗间隔时间是头颈部肿瘤患者放疗后颈动脉损伤的危险因素.     

血管回声追踪技术评价亚临床甲状腺功能减退患者颈动脉血管内皮功能

目的 探讨血管回声追踪(E-Tracking)技术评价亚临床甲状腺功能减退患者颈动脉血管内皮功能的应用价值.方法 38例亚临床甲状腺功能减退患者及60例正常者,应用E-Tracking技术检测双侧颈总动脉弹性模量(Ep)、僵硬度(β)、顺应性(AC)、膨大系数(AI)及脉搏波传导速度(PWVβ).结果 亚临床甲状腺功能减退组Ep、β、AI、PWVβ与正常对照组比较明显升高,AC降低,差异有统计学意义(P＜0.05).结论 亚临床甲状腺功能减退患者易发生早期动脉血管内皮功能损伤,E-Tracking技术有助于早期发现及定量分析.     

血管回声跟踪技术评价甲状腺功能减退症颈动脉弹性的临床研究

目的 探讨血管回声跟踪技术(echo-tracking,ET)对甲状腺功能减退症(甲减)患者颈动脉壁弹性的诊断价值.方法 应用ET技术对32例甲减患者和30例正常人右侧颈总动脉进行超声检测,评估颈动脉弹性参数指标,包括硬化参数(β)、血管压力应变弹性系数(Eρ)、血管顺应性(AC)、脉搏波增大指数(AI)及脉搏波传导速度(PWVβ),将两组参数进行比较.结果 与对照组相比,甲减组β、Eρ和PWVβ明显升高,AC显著减低(P＜0.05),AI无显著性差异(P＞0.05).β、Eρ、PWVβ值的升高可能继发于甲状腺激素水平的降低.结论甲减患者颈动脉弹性明显低于正常对照组,ET技术为甲减患者颈动脉的弹性检测提供了一种快捷、无创的早期评价方法 .     

血管回声跟踪技术评价妊娠期高血压疾病患者血管内皮功能

目的 探讨血管回声跟踪(E-Tracking,ET)技术评价妊娠期高血压疾病患者动脉血管内皮功能的应用价值.方法 对妊娠期高血压疾病患者45例(妊娠期高血压患者25例,子痫前期患者20例)及正常妊娠女性60例,应用ET技术测量双侧颈总动脉及肱动脉的硬化度(β)、弹性系数(Eρ)、动脉顺应性(AC)、膨大系数(AI)及单点脉搏波传导速度(PWVβ).结果 妊娠期高血压组和子痫前期组β、Eρ、AI、PWVβ与对照组比较明显升高,AC降低,差异有显著性(P<0.05).子痫前期组与妊娠期高血压组比较:β、Eρ、AI、PWVβ明显升高,AC明显降低,差异有显著性(P<0.05).结论 血管回声跟踪技术能够早期,简便、准确地反映妊娠期高血压疾病患者血管内皮功能的变化.     

血管回声跟踪技术及超声弹性成像评价2型糖尿病患者足背动脉弹性功能

目的 运用血管回声跟踪技术及超声弹性成像技术探讨不同病程的2型糖尿病患者足背动脉弹性功能的变化.方法 测量83例2型糖尿病患者(43例病程＜10年者,为DM-Ⅰ组;40例病程≥10年,为DM-Ⅱ组)及35名健康志愿者(对照组)的踝部动脉和肱动脉的血压,并计算踝臂指数(ABI);应用超声弹性成像技术计算足背动脉的管壁弹性应变率比值(B/A),应用血管回声跟踪技术计算足背动脉的僵硬度(β)、弹性模量(Eρ)、顺应性(AC)、膨大系数(AI)及脉搏波传导速度(PWVβ)的变化.结果 与对照组及DM Ⅰ组比较,DM-Ⅱ组足背动脉β、Eρ、PWVβ及B/A升高,内-中膜厚度(IMT)增加,AC及ABI降低(P均＜0.05),但AI差异无统计学意义;与对照组比较,DM-Ⅰ组足背动脉β、Eρ、PWVβ及B/A升高,AC降低(P均＜0.05),IMT、ABI及AI差异无统计学意义.结论 β、Eρ、AC、PWVβ及B/A可早期反映动脉弹性功能变化;血管弹性功能的改变早于血管形态学的改变;2型糖尿病病程长短对足背动脉弹性功能有影响,病程≥10年者足背动脉血管弹性功能显著降低.     

E-tracking技术对妊娠期高血压疾病患者颈动脉弹性功能的研究

目的:探讨血管回声跟踪(E-Tracking,ET)技术评价妊娠期高血压疾病患者颈动脉弹性功能的改变。材料与方法:对妊娠期高血压疾病患者(孕28周后)49例和66例正常妊娠期孕妇(孕28周后)进行双侧颈总动脉血管弹性指标的测量:弹性模量(Eρ)、僵硬度(β)、顺应性(AC)、膨大指数(AI)和脉搏波传导速度(PWVβ),并进行统计学分析。结果:妊娠期高血压疾病组双侧颈总动脉Eρ、β、AC及AI较对照组升高,AC较对照组减低,具有显著性差异(P<0.05,P<0.01)。结论:血管回声跟踪技术能较早、明确的反映妊娠期高血压疾病患者颈动脉弹性功能的改变,具有一定价值。     

血管回声跟踪技术对正常高值血压者颈总动脉弹性的研究

目的 探讨血管回声跟踪（ET）技术检测正常高值血压者颈总动脉弹性功能的变化情况及其临床意义.方法 应用ET技术检测63例正常高值血压者（HNBP组）与50例健康成人（正常对照组）双侧颈总动脉的弹性参数,包括弹性系数（β）、僵硬度（Eρ）、顺应性（AC）、增大指数（AI）及单点脉搏波传导速度（PWVβ）,并使用常规血管超声测量颈动脉内-中膜厚度（IMT）,结果进行对比分析.结果 组内双侧颈总动脉的IMT及其各弹性参数比较差异均无统计学意义;两组间上述各指标比较,HNBP组的β、Eρ和PWVβ增高,AC降低,差异均有统计学意义（P 〈 0.01）,AI和IMT无明显变化,差异无统计学意义.结论 正常高值血压者颈总动脉Eρ增加,ET技术能较早发现颈总动脉弹性的改变,对临床早期预防心脑血管疾病的发生具有重要意义.     

Use of crystepin in combination with obsidan in patients with diabetes mellitus with arterial hypertension

Examination included 70 patients with diabetes mellitus in combination with arterial hypertension of different origin (II stage essential hypertension and symptomatic renal arterial hypertension). Crystepin (2-3 tablets per 24 h) in combination with beta-adrenoblocker obsidan (40-80 mg/24 h) was used for treatment. Basic hemodynamic parameters and the state of the renin-aldosterone system were determined. The hemodynamic hypotensive effects in these patients due to the influence of the above therapy are uniform and depend on the form of attendant arterial hypertension. The hypotensive effect of crystepin used in combination with obsidan was more pronounced in patients with diabetes and II stage essential hypertension than that in those with diabetes and renal hypertension. The concentration of aldosterone and renin activity of blood plasma in patients with diabetes and arterial hypertension during treatment with crystepin and obsidan had no regular connection with the hemodynamic parameters.     

硝酸甘油联合托拉塞米在高血压危象并发急性肺水肿患者的应用

目的研究硝酸甘油联合托拉塞米治疗高血压危象合并急性肺水肿的效果。方法选取我院收治的高血压危象合并急性肺水肿患者80例作为研究对象。随机分为对照组40例,采用托拉塞米治疗;试验组40例,采用硝酸甘油联合托拉塞米治疗。比较两组患者治疗效果、临床指标改善程度及并发症发生率。结果治疗后对照组患者血压、呼吸频率及氧分压改善程度均低于试验组,且治疗有效率(77.5%)低于试验组(92.5%),差异显著(P0.05);对照组患者并发症发生率(20.0%)高于试验组(7.5%),差异显著(P0.05)。结论采用硝酸甘油联合托拉塞米在治疗高血压危象合并急性肺水肿安全性高,可减少并发症,改善治疗效果,提高患者生活质量。     

Observations with Rabenid in patients with locomotor disease

By examining 139 patients suffering from locomotor diseases the author could observe the characteristic accompanying diseases as well as high uric acid level in 40 cases. She analyses the current opinions on hyperuricaemia and reports on her observations with uricosuric and antithrombotic coated Rabenid tablet (RG). She found sulfinpyrazone to be effective and valuable in the examined indication field.     

Satisfaction with upper-extremity surgery in individuals with tetraplegia

OBJECTIVE: To measure the satisfaction of individuals with tetraplegia with their upper-extremity reconstructive surgery. DESIGN: Survey. SETTING: Two Spinal Cord Injury Model Systems centers. PARTICIPANTS: Sixty-seven individuals with spinal cord injury at the C4 through C8 motor level (107 arms). INTERVENTIONS: Participants had upper-extremity surgery to improve function. The surgical procedures included tendon transfers for elbow extension, wrist extension, hand grasp, and pinch or hand grasp neuroprosthesis. MAIN OUTCOME MEASURE: A survey was mailed to participants, who were asked to respond to statements such as, "If I had it to do over, I would have the hand/arm surgery again," using a 5-level Likert scale (ranging from strongly agree to strongly disagree). RESULTS: Seventy percent of the participants were generally satisfied with the results of their upper-extremity surgery, 77% reported a positive impact on their lives, 68% reported improvements in activities of daily living (ADLs), 66% reported improved independence, 69% reported improvement in occupation, 71% reported improved appearance or neutral, 78% reported their hand worked as well (or neutral) as it did when surgery was first performed, and 86% reported postoperative therapy as being beneficial. CONCLUSIONS: Upper-extremity surgery had a positive impact on life, increased ability to perform ADLs and to be independent, and improved quality of life.     

Changes in myocardial function in patients with hypertension during treatment with minipress

Altogether 33 patients with arterial hypertension were investigated to study changes of left ventricular systolic phasic analysis, caused by prazosin therapy. Two groups were identified on the basis of these changes: indices in the 1st group (intrasystolic index, myocardial tension index, Blumberger coefficient) improved, in the 2nd group they deteriorated. The antihypertensive effect of prazosin should be assessed not only by the level of BP reduction but also by changes of left ventricular systolic phasic analysis. In the deterioration of indices of left ventricular systolic phasic analysis during a test with single administration of prazosin, antihypertensive therapy should be reconsidered.     

Satisfaction with medical rehabilitation in patients with orthopedic impairment

OBJECTIVE: To examine patient satisfaction after orthopedic impairment at 80 to 180 days after inpatient rehabilitation. DESIGN: Retrospective design examining records from facilities subscribing to the Uniform Data System for Medical Rehabilitation (UDSmr). SETTING: Information submitted to UDSmr from 1997 to 1998 by 177 hospital and rehabilitation facilities from 40 states. PARTICIPANTS: The sample (N=7781) was 72.63% female and 88.60% non-Hispanic white, with a mean age +/- standard deviation of 73.07+/-11.81 years, and average length of stay (LOS) of 13.84+/-10.48 days. INTERVENTION: Usual rehabilitation care.Main outcome measures Level of satisfaction 80 to 180 days after discharge as well as motor, cognitive, and subscale ratings for the FIM trade mark instrument. Predictor variables included gender, age, English language, marital status, discharge setting, LOS, rehospitalization, FIM gain, and primary payer. RESULTS: A logistic regression model was used to predict patient satisfaction at follow-up. Five statistically significant (P<.05) variables were found and correctly classified 94.9% of the patients. Discharge motor FIM rating, rehospitalization, age, patient's primary language, and discharge setting were associated with increased satisfaction. Discharge motor FIM ratings were significantly associated with increased satisfaction in patients with joint replacements and lower-extremity fractures. CONCLUSION: unctional and demographic variables were identified as predictors of satisfaction in patients with orthopedic impairments.