标准外伤大骨瓣开颅术治疗重型颅脑损伤分析

目的比较标准外伤大骨瓣与常规骨瓣开颅术治疗重型颅脑损伤的效果.方法符合重型颅脑损伤诊断标准的患者91例,分标准外伤大骨瓣治疗组和常规骨瓣对照组两组.标准外伤大骨瓣治疗组(n=48),行单侧或双侧额颞顶标准外伤大骨瓣开颅减压术;常规骨瓣对照组(n=43),行单侧或双侧颞顶瓣或额颞瓣开颅术.所有患者都经CT扫描证实颅脑损伤情况.结果伤后随访,标准外伤大骨瓣治疗组:20例预后较好(41.67%),其中恢复良好8例,中残12例;28例预后较差(58.33%),其中重残9例,植物状态6例,死亡13例;常规骨瓣对照组:8例预后较好(18.60%),其中恢复良好4例,中残4例;35例预后较差(81.40%),其中重残15例,植物状态3例,死亡17例,两者比较差异有统计学意义(P<0.05).标准外伤大骨瓣治疗组的术中急性脑膨出、迟发性血肿、再次手术、脑脊液漏发生率低于常规骨瓣对照组(P<0.05),但两组患者术后外伤性脑积水、术后外伤性癫痫和颅内感染发生率差异无统计学意义(P>0.05).结论标准外伤大骨瓣开颅减压术治疗重型颅脑损伤效果优于常规骨瓣开颅术.     

标准外伤大骨瓣减压术治疗额颞顶部重型颅脑损伤预后分析

目的评价标准外伤大骨瓣减压手术治疗额颞顶部重型颅脑损伤的疗效。方法 38例重型颅脑损伤患者采用标准外伤大骨瓣开颅减压手术治疗,并与同期收治的32例常规骨瓣开颅手术组进行比较,分析其疗效。结果标准外伤大骨瓣减压手术治疗组38例中,恢复良好25例(65.8%),死亡6例(15.8%);常规骨瓣开颅手术组32例中,恢复良好12例(37.5%),死亡13例(40.6%),2组恢复良好率和病死率差异有统计学意义(P<0.05),标准外伤大骨瓣减压手术治疗组预后明显优于常规骨瓣开颅手术组。结论标准外伤性大骨瓣内外减压手术能明显改善额颞顶部重型颅脑损伤患者的预后,并降低病死率。     

标准外伤大骨瓣与常规骨瓣开颅术治疗重型颅脑损伤的对照研究

目的 比较标准外伤大骨瓣开颅术与常规骨瓣开颅术对重型颅脑损伤的治疗效果.方法 将符合标准的78例重型颅脑损伤患者随机分为标准外伤大骨辩组38例和常规骨瓣组40例,比较两组术后的颅内压变化、并发症发生率及预后.结果 标准外伤大骨瓣组的颅内压下降速度和幅度大于常规骨瓣组(P＜0.05),术后切口疝发生率明显低于常规骨瓣组(X2=-4.68,P＜0.05),而两组术后急性脑膨出、脑脊液漏,外伤性癫痫和颅内感染发生率均差异无显著性(P＞0.05),术后1月神经功能缺损程度评分的改善情况比较,标准外伤大骨瓣组优于常规骨瓣组(t=6.27,P＜0.01).术后随访6个月,标准外伤大骨辩组的存活率和良好率均优于常规骨辩组(X2=6.57,P＜0.05;X2=-4.36,P＜0.05).结论 标准外伤大骨瓣开颅术具有显露充分、操作方便和减压彻底等优点,是治疗重型颅脑损伤的有效方法.     

标准外伤大骨瓣在重型颅脑外伤治疗中的临床疗效分析

目的 分析标准外伤大骨瓣开颅术治疗重型颅脑损伤的临床优势.方法 收集近期笔者所在医院治疗的重型颅脑损伤40例患者的临床资料,均采用标准外伤大骨瓣开颅术,并与24例行常规骨瓣开颅术患者比较,分析两组颅内压及术后GOS评分.结果 标准外伤大骨瓣开颅术组术后颅内压显著降低,并明显低于常规去骨瓣组治疗后;术后恢复良好率37.5%(15/40),显著高于常规去骨瓣组(P<0.05).结论 在把握适应证基础上,标准外伤大骨辫治疗重型颅脑临床疗效明显.     

标准外伤骨瓣与常规骨瓣治疗重型颅脑损伤临床对照研究

目的：比较标准外伤骨瓣与常规颞顶瓣开颅术在治疗224例重型颅脑损伤效果。方法：收治符合标准的重型颅脑损伤病人224例,分为两组：（1）标准外伤大骨瓣组115例,（2）常规骨瓣组109例。所有病人都经CT扫描证实颅内损伤状况。标准外伤大骨瓣治疗组采用美国标准外伤骨瓣开颅减压术（12cm&#215;15cm）,去除骨瓣,扩大硬膜腔减张缝合。常规骨瓣对照组根据血肿部位采用单侧或双侧颞顶瓣或额颞瓣开颅减压方法（6cm&#215;8cm）。结果：标准骨瓣治疗组病人恢复良好明显高于常规骨瓣对照组,长期昏迷和中残率低于常规骨瓣组（P〈0．05）,标准骨瓣治疗组患者的迟发眭血肿和切口脑脊液漏发生率均低于常规骨瓣组（P〈0．05）。结论：标准外伤骨瓣开颅术治疗重型颅脑创伤合并严重脑挫裂伤脑水肿、恶性颅内高压病人的疗效明显好于常规颞顶瓣开颅术。     

标准大骨瓣开颅治疗重型颅脑损伤疗效观察

目的探讨标准大骨瓣开颅术治疗重型颅脑损伤病人应用效果。方法将89例重型颅脑损伤患者随机分成标准外伤大骨瓣开颅组和常规骨瓣组,两组患者均接受手术治疗,标准大骨瓣开颅组45例,常规骨瓣组44例,术后随访6个月,按GOS法观察手术疗效。结果标准外伤大骨瓣开颅组与常规骨瓣组比较,疗效有显著性差异(P<0.05)。结论标准外伤大骨瓣开颅术能充分降低颅内压,对降低重型颅脑损伤患者的病死率、改善预后均有重要意义。     

标准外伤大骨瓣开颅减压术与常规骨瓣开颅术治疗额颞部重型颅脑损伤的效果比较

目的对比标准外伤大骨瓣开颅减压术与常规骨瓣开颅术治疗额颞部重型颅脑损伤的临床效果。方法选取2016年1月至2018年1月郑州市第一人民医院收治的82例额颞部重型脑损伤患者,按照手术方式分为常规组和标准组,各41例。常规组接受常规骨瓣开颅术治疗,标准组接受标准外伤大骨瓣开颅减压术治疗。比较两组术后脑组织切口疝、颅内高压发生情况及预后。结果标准组术后脑组织切口疝发生率为7.32%(3/41)、颅内高压发生率为12.20%(5/41),均低于常规组的24.39%(10/41)、34.15%(14/41),差异有统计学意义(均P<0.05)。标准组预后良好率、病死率分别为43.90%(18/41)、7.32%(3/41),高于常规组的21.95%(9/41)、24.39%(10/41),差异有统计学意义(均P<0.05)。结论标准外伤大骨瓣开颅减压术治疗额颞部重型颅脑损伤,可显著降低患者脑组织切口疝、颅内高压发生率,改善预后,降低病死率,值得临床推广。     

标准外伤大骨瓣减压术治疗额颞顶部重型颅脑损伤预后分析

目的 评价标准外伤大骨瓣减压手术治疗严重对冲性颅脑损伤的疗效.方法 38例重型额顶部重型颅脑损伤患者采用标准外伤大骨瓣开颅减压手术治疗,并与同期收治的32例常规骨辩开颅手术组进行比较,分析其疗效.结果 标准外伤大骨瓣减压手术治疗组38例中,恢复良好25例(65.78%),死亡6例(15.79%);常规骨瓣开颅手术组32例中,恢复良好12例(37.50%),死亡13例(40.62%),两组恢复良好率和死亡率差异有显著性(P<0.05),标准外伤大骨瓣减压手术治疗组预后明显优于常规骨瓣开颅手术组.结论 标准外伤大骨瓣内外减压手术能明显改善额颞顶部重型颅脑损伤患者的预后,并降低死亡率.     

双侧标准外伤大骨瓣开颅手术治疗重型颅脑损伤的临床分析

目的:分析双侧标准外伤大骨瓣开颅手术治疗重型颅脑损伤的效果.方法:选取我院收治的64例重型颅脑损伤患者作为此次研究的分析对象,并按随机分配数字表达法将其分为研究组与对照组,各32例.对照组运用双额冠状骨瓣开颅去骨瓣减压术,研究组运用双侧标准外伤大骨瓣开颅手术,比较两组的颅内压变化情况.结果:对照组术后3日与术后7日的颅内压高于研究组,有统计学差异存在(P＜0.05).结论:对重型颅脑损伤患者运用双侧标准外伤大骨瓣开颅手术,能促使颅内压降低,建议临床应用与推广.     

标准大骨瓣开颅血肿清除对重度颅脑外伤侧裂区损伤致单侧脑肿胀的疗效观察

目的 探讨标准大骨瓣开颅血肿清除去大骨瓣减压术对重度颅脑外伤侧裂区损伤致单侧脑肿胀的疗效.方法 57例重度颅脑外伤侧裂区损伤致单侧脑肿胀患者随机分成观察组(32例)和对照组(25例),分别采用标准和常规大骨瓣开颅血肿清除术治疗.观察并比较两组患者术后的格拉斯哥评分(GCS)、颅内压(ICP)、脑水肿体积、中线移位情况和生存率.结果 观察组术后3 d和7 d时评分GCS明显高于对照组,而ICP、脑水肿体积和中线移位均明显少于对照组,差异有统计学意义(P<0.05);术后随访1年,观察组生存率为75%,明显高于对照组的48%,差异有统计学意义(χ2=4.39,P<0.05).结论 标准大骨瓣开颅血肿清除去大骨瓣减压术可以明显改善重度颅脑外伤侧裂区损伤致单侧脑肿胀患者的预后,降低病死率.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.