河津市人类免疫缺陷病毒/艾滋病感染状况及流行病学分析

目的 分析河津市人类免疫缺陷病毒(HIV)/艾滋病(AIDS)病例的流行病学资料,为制定艾滋病防治策略提供依据.方法 对2001-2009年HIV/AIDS病例流行病调查资料、HIV抗体检测资料进行分析.结果 我市2001-2009年,累计发现HIV/AIDS病例68例,累计管理HIV/AIDS 39例中,传播途径以性传播为主,首次发现同性性传播艾滋病病例.2009年在孕产妇中发现HIV阳性病例.结论 河津市艾滋病疫情正由高危人群向一般人群转移,要依据艾滋病流行情况,及时制定有针对性的措施,以有效预防和控制艾滋病.     

116例新发现HIV/AIDS流行病学分析

目的了解新发现的艾滋病病毒感染者(HIV)和艾滋病病人(AIDS)的流行病学特征,为制定艾滋病防控措施提供依据。方法对石家庄市2009年新发现报告的116例HIV/AIDS的人群特征和流行病学调查资料进行统计分析。结果 2009年新发现报告的HIV/AIDS以男性、青壮年为主,集中在初中及以下文化程度的低社会阶层,57.76%为流动人口;以性传播为主;75.87%通过被动检测发现;77.59%为没有症状的感染者。结论性传播已成为目前艾滋病流行的主要传播途径。今后应加强艾滋病防治知识和国家政策的宣传,特别对较低社会阶层和重点人群进行宣教和干预,促使高危人群及时主动进行检测,及早发现感染者,防治艾滋病的进一步蔓延。     

佳木斯市艾滋病抗病毒治疗患者生存率及影响因素分析

目的 了解佳木斯市艾滋病病毒感染和艾滋病患者(HIV/AIDS)抗病毒治疗(HAART)生存率,并分析影响因素。方法 采用回顾性队列研究,通过《中国疾病预防控制信息系统》采集佳木斯市疾病预防控制中心2009年6月至2019年7月收治的HIV/AIDS HAART患者的一般资料,采用寿命表法计算生存率,采用多因素Cox比例风险模型分析生存时间的影响因素。结果 共纳入1986例HIV/AIDS HAART患者,其中死于HIV/AIDS相关疾病48例(占2.42%),HIV/AIDS HAART的1、3、5、10年累积生存率分别为98.44%、97.84%、97.47%、96.29%;多因素Cox比例风险模型分析结果显示,经血感染HIV(HR=3.125)、开始治疗时年龄30～(HR=4.518)、开始治疗时年龄50～(HR=15.897)、有漏服药(HR=5.647)的HIV/AIDS HAART患者死亡的危险较大,高中及以上文化程度(HR=0.264)、基线CD4+T淋巴细胞计数350个/μL(HR=0.183)的HIV/AIDS HAART患者死亡的危险较小。结论2009年6月至2019年7月佳木斯市HIV/AIDS HAART患者生存率较高,经血感染、HAART时年龄较大、有漏服药是HIV/AIDS HAART患者生存的危险因素,高中及以上文化程度、基线CD4+T淋巴细胞计数350个/μL是HIV/AIDS HAART患者生存的保护因素。     

2004-2009年广西靖西县淋病、梅毒、AIDS/HIV流行状况分析

目的了解位于中越边境的靖西县2004-2009年梅毒、淋病、艾滋病感染及发病情况,分析其流行特征和规律,为制订性病艾滋病防治策略和措施提供科学依据。方法收集该县2004-2009年的梅毒、淋病、AIDS/HIV病例疫情资料,采用Excel软件进行统计分析。结果全县人口数为61.7万,近6年报告梅毒、淋病、AIDS/HIV阳性病例共767例,人群发病率为21.68/10万,男性高于女性,其中淋病118例、梅毒595例、艾滋病11例(死亡6例)、HIV阳性43例(死亡10例)。以上3种疾病高发年龄在15～44岁年龄组,占总发病率的68.06%。农民发病人数占59.06%。梅毒病例数2007年后增多明显。自1997年发现HIV感染者后,2004-2009年AIDS/HIV患者每年有所增加,病死率呈逐年上升,平均病死率为29.63%。结论该县2004-2009年梅毒患者增加较快,AIDS/HIV阳性病例有所增多,防治工作应进一步加强。     

深圳市龙岗区新确证HIV/AIDS病例的亚型分布及耐药分析

目的 了解深圳市龙岗区新增确证艾滋病病毒感染者(HIV)/艾滋病病人(AIDS)的流行病学特征、HIV-1亚型分布及耐药株流行状况,为当地的艾滋病防控提供参考依据.方法 对深圳市龙岗区2016-2019年新报告HIV/AIDS病例开展流行病学横断面研究,按年分层随机抽取432例HIV/AIDS患者血清并提取病毒RNA,...     

新疆两地州(市)艾滋病病毒感染者/艾滋病病人子女艾滋病感染状况及既往检测状况调查

目的掌握新疆两地州(市)艾滋病病毒感染者/艾滋病病人(HIV/AIDS病人)子女艾滋病感染状况及既往检测状况,为今后有针对性地制定防治措施提供科学依据。方法以新疆乌鲁木齐市和伊犁哈萨克自治州16个县(市/区)HIV/AIDS病人子女659名作为研究对象,获得HIV/AIDS病人或其家属知情同意后行问卷调查和咨询,并采血检测。结果 659名HIV/AIDS病人子女中,15名HIV检测阳性(2.28%),既往做过艾滋病检测者429人(65.1%),HIV/AIDS病人子女的家长知道自身检测结果者494人(78.2%)。乌鲁木齐市与伊犁哈萨克自治州及维吾尔族与其他民族HIV/AIDS病人子女既往HIV检测状况差异均有统计学意义,维吾尔族HIV/AIDS病人子女的家长与其他民族、HIV抗体阴性结果子女的家长与阳性结果子女的家长知道自身检测结果比较,差异均有统计学意义。结论新疆两地州(市)HIV/AIDS病人子女艾滋病既往检测率、HIV/AIDS病人子女家长的检测率低,应进一步落实新疆"逢孕必检"的措施,加强对HIV/AIDS病人及其家庭的健康教育,提高对艾滋病知识的认知程度,深化干预策略。     

内蒙古自治区2012-2019年艾滋病相关死亡影响因素分析

目的 了解内蒙古自治区2012-2019年艾滋病病毒感染者与艾滋病病例(HIV/AIDS)死亡分布特征以及相关死亡影响因素,为提高HIV/AIDS病例的预防干预工作水平提供理论基础.方法 在全国艾滋病综合防治信息系统中收集现住址为内蒙古自治区且2012-2019年发生死亡的HIV/AIDS病例报告卡,应用SPSS 22...     

艾滋病患者心脏损害63例分析

艾滋病即获得性免疫缺陷综合征(AIDS),是由免疫缺陷病毒(HIV)引起的慢性传染病.艾滋病累及多系统器官,心脏亦常被累及.回顾分析笔者所在医院2005年1月至2009年9月所收治的艾滋病患者143例,其中63例出现心脏损害,发生率44.1%.     

清远市艾滋病流行情况分析

目的:分析清远市艾滋病(HIV／MDS)流行现状，为预防控制HIV／AIDS提供科学依据。方法:收集近年疫情报告、HIV／AIDS监测和流行病学调查资料进行分析。结果:1999～2003年累计发现艾滋病病毒感染(HIV)50例，其中艾滋病人(AIDS)4例，死亡2例。2003年吸毒人群HIV抗体检出率5．62％，静脉吸毒血液传播占68％，性途径传播占22％，并已出现3户家庭的夫妻共同感染HIV／AIDS。结论:清远市目前HIV／AIDS尚处于低度流行期，但感染HIV人数逐年呈倍数增加，HIV／AIDS已从高危人群向一般人群扩散，呈现快速增长趋势。开展健康宣传教育和减少危害的行为干预等综合性防制措施，对有效遏制HIV／AIDS的扩散流行甚为迫切。     

小鼠艾滋病动物模型研究概况(综述)

自从1981年美国报道首例人类艾滋病(AequiredImmunodeficiencySyndrome,AIDS)以来,全世界已有163个国家和地区发现了AIDS,约有1000万人感染了人类免疫缺陷病毒(HumanImmunodeficiencyVirus,HIV)。目前,HIV仍以惊人的速度传播,严重危害人类的健康。为了征服人类AIDS,国外许多学者已进行了大量AIDS动物模型的研究,并相继建立了猴艾滋病(SimianAIDS,SAIDS)、猫艾滋病(FelineAIDS,FAIDS)和小鼠艾滋病(MurineAIDS,     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.