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目的:探讨症状性Rathke囊肿的诊断和治疗方法。方法:18例症状性Rathke囊肿病例均采用经单鼻孔蝶窦入路显微外科手术治疗,切除部分囊壁,敞开囊腔,清除囊肿内容物。结果:术后随诊3个月至10年,18例患者的症状均有缓解,4例患者术后复发。结论:鞍区症状性Rathke囊肿术前较难明确诊断,CT/MRI检查呈多样性,无特异性。经单鼻孔蝶窦入路显微外科手术可明确诊断,缓解症状,患者预后良好,是治疗垂体Rathke囊肿的有效方法。病例复发与鳞状上皮化生有关。 相似文献
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目的:探讨鞍区Rathke囊肿的诊断和手术治疗.方法:对6例Rathke囊肿病例采用单鼻孔蝶窦入路、翼点入路和眉弓锁孔入路显微神经外科手术治疗,切除部分囊壁,敞开囊腔,清除囊肿内容物.结果:术后随诊6mo~3a,本组症状均有缓解,3a均未复发.结论:鞍区Rathke囊肿CT、MRI检查无特异性,术前较难明确诊断.经单鼻孔蝶窦入路显微外科手术是其有效治疗方法,可以明确诊断,缓解症状,病人预后良好,是治疗垂体Rathke囊肿的有效办法. 相似文献
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目的 探讨垂体Rathke's囊肿MRI的影像特征和诊断价值.方法 鞍区垂体囊肿性病变18例,行鞍区薄层T1WI和T2WI矢状位和冠状位扫描以及T1WI冠状位动态增强扫描,在半年内追踪复查1次,结合临床资料由2名以上高年资医师分析其影像表现.结果 15例鞍区囊肿性病变表现为矢状位垂体中后1/3的圆形、椭圆形肿块,冠状位居垂体中央或偏居一侧.2例鞍区囊肿性病变表现为矢状位垂体腺体部底部的扁丘状小肿块.1例鞍区囊肿性病变表现为冠状位两分叶状改变,上部相对小居垂体上缘,下部相对较大居垂体右侧缘.多数囊肿性病变主要位于鞍内,少数可向鞍上发展,大小0.3~1.2 cm,信号多变,增强后有2例病灶边缘环形轻度强化信号,18例半年内追踪复查一次,垂体囊肿性病变的位置、大小、信号和增强均无明显变化.18例鞍区垂体囊肿性病变均诊断为垂体Rathke's囊肿.结论 垂体Rathke's囊肿在MRI影像上有特征性表现,复查MRI对少数特殊Rathkes囊肿的诊断有帮助. 相似文献
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目的探讨直接经单侧鼻腔-蝶窦入路显微手术切除垂体瘤的疗效。方法对18例垂体肿瘤患者CT扫描或MRI明确手术适应症后,均采取经单侧鼻腔-蝶窦入路显微手术切除肿瘤。结果全切17例,次全切除1例。视力视野改善11例,头痛均减轻或消失,月经恢复5例;发生-过性尿崩2例,脑脊液漏1例,无鼻梁塌陷、上门齿麻木及鼻中隔穿孔等并发症,无手术死亡病例。结论只要病例选择得当,单则鼻腔经蝶入路垂体瘤切除术具有鼻腔结构损伤小,切除肿瘤彻底,术后并发症少等优点。 相似文献
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经单侧鼻孔-蝶窦入路切除垂体腺瘤 总被引:3,自引:0,他引:3
目的:介绍经单鼻孔蝶窦入路行垂体腺瘤的显微手术方法,常见并发症及处理方法。方法:手术显微镜下采用经单鼻孔蝶窦入路切除垂体腺瘤32例。沿一侧鼻腔置牵开器至蝶窦前壁中下部,将鼻中隔完整推向对侧,根据解剖定位进入蝶窦,打开鞍底切除肿瘤。结果:本组手术经过顺利,无严重并发症。结论:经解剖定位单鼻孔-蝶窦入路切除垂体腺瘤准确、并发症少、省时,是切除垂体腺瘤理想的手术入路。 相似文献
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目的:探讨脑垂体脓肿的影像学特点。方法 :15例经手术和病理证实的垂体脓肿患者,术前均行CT扫描和鞍区MRI平扫及增强扫描。结果 :CT示7例鞍区呈等密度,5例呈低密度,1例呈略高密度病灶,2例呈混杂密度病灶,边界均清楚;MRI示11例长T1,长T2信号,2例呈等T1,长T2信号,13例显示增强后可见囊壁环形强化,且冠状位上均可见垂体柄增粗及强化,为中枢性尿崩提供了形态学上的线索。结论:垂体脓肿的影像学有特征性,术前CT提示鞍区边界清楚的等密度或略高密度病灶,鞍区磁共振及增强示类圆形囊状占位性病变,等或长T1,长T2,囊壁呈环形强化,伴蝶窦内粘膜增厚等,尤其是术前合并尿崩者应考虑垂体脓肿的诊断。 相似文献
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目的:探讨并总结经单鼻孔蝶窦入路手术的适应证、技巧及术后处理。方法:60例鞍区占位患者充分术前准备,采取经单鼻孔蝶窦手术入路治疗,术中严格中线操作,有序切除病变组织,部分重建鞍底。术后监测实验室指标、积极纠正内环境失衡等。结果:术后病理证实垂体腺瘤47例,拉克氏囊肿6例,垂体脓肿4例,颅咽管瘤3例;手术全切52例,大部切除8例;术后尿崩39例,电解质紊乱35例,1个月后激素异常7例,抽搐发作6例,垂体危象4例,无脑脊液鼻漏、颅内感染及死亡病例。结论:经单鼻孔蝶窦入路手术适用于切除鞍区占位性病变;术中确定中线结构并严格中线操作、有序切除病变、不漏水性封闭、并适时鞍底重建是手术成功的关键;积极纠正内环境紊乱是术后安全的有力保障。 相似文献
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Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD. 相似文献
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Jiageng Zhu Jun Li Ruipeng Ji Jianghao Su Mingshun Shen Zhigang Cao 《南京医科大学学报(自然科学版)》2007,21(2):125-128
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment. 相似文献
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APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES 总被引:13,自引:0,他引:13
Hong Zhao Tie-hu Ye* Zhi-yi Gong Yang Xue Zhang-gang Xue and Wen-qi HuangDepartment of Anesthesiology Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing Department of Anesthesiology Zhongshan Hospital Fudan University Shanghai Department of Anesthesiology the First Affiliated Hospital Zhongshan University Guangzhou 《中国医学科学杂志(英文版)》2005,20(1):59-62
FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle… 相似文献
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Tao Ye * Zhi-quan Liu Jian-jun Mu Xi-han Fu Jun Yang Bao-lin Gao and Xiao-hong Zhang Department of Cardiology First Hospital of Xi'an Jiaotong University Xi'an Hanzhong Cardiovascular Institute Hanzhong 《中国医学科学杂志(英文版)》2004,19(4):248-251
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure. 相似文献
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Xi-zhao Sun Zhi-wei Zhang 《中国医学科学杂志(英文版)》2005,20(3):221-221
Shock wave lithotripsy (SWL) is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it's difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath. 相似文献
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Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction. 相似文献
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INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5 相似文献
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People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia its metabolic origin in Tibetan population.…… 《中国医学科学杂志(英文版)》2007,22(2):F0003-F0003
People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population. 相似文献
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Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea. 相似文献
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In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects. 相似文献