上海市区恶性肿瘤发病趋势分析(1972～1999年)

目的对上海市区1972～1999年肿瘤发病资料进行统计、分析,了解肿瘤发病率的变化趋势.方法病例统一按照国际疾病分类(ICD-9)进行编码.根据人口普查资料中的性别、年龄构成用内插法和外推法估算各年的年龄组平均人口数.用世界标准人口计算标化率.发病率每年变化百分比,用对数直线回归法估计,并用病例数加权.结果 1972～1999年间,男性所有部位肿瘤标化率从250.0/10万降至214.8/10万,女性从175.3/10万降至163.4/10万.男女性结肠癌、胆道癌、肾癌,男性前列腺癌、多发性骨髓瘤以及女性脑和神经系统肿瘤的发病率上升幅度均达到100%及以上.男女性胰腺癌、直肠癌、非何杰金淋巴瘤、男性脑和神经系统肿瘤、女性乳腺癌、宫体癌、卵巢癌的发病率呈明显上升趋势.男女性食管癌和女性宫颈癌的发病率下降幅度达到一半以上,胃癌和肝癌的发病率也呈明显下降趋势,肺癌发病率在男、女性别中均变化不大.结论上述发病率变化趋势提示除了肿瘤诊断和报告情况的改善外,包括居民生活方式在内的环境因素的变化起着重要作用,需要深入开展流行病学研究,明确危险因素,提出有效的预防方法.     

2004～2011年上海市卢湾区户籍人口常见妇科恶性肿瘤发病和死亡趋势分析

[目的]分析上海市卢湾区户籍人口2004～2011年常见妇科恶性肿瘤的发病率和死亡率.[方法]系统整理上海市肿瘤登记报告中卢湾区户籍人群2004年1月至2011年12月常见妇科恶性肿瘤(宫颈癌、宫体癌、卵巢癌)发病和死亡资料,计算和分析发病率、死亡率,用中国2000年人口普查人口结构计算标化率.并做发病率及死亡率的趋势比较分析.[结果]2004～2011年,上海市卢湾区共报告宫颈癌新发病例120例、宫体癌166例、卵巢癌170例,共占同期全区女性恶性肿瘤的7.09％.2004～2011年三种肿瘤的发病率波动较明显.宫颈癌的发病高峰在35～55岁之间,宫体癌与卵巢癌的发病在45岁之后显著升高.死亡病例宫颈癌55例、宫体癌49例、卵巢癌88例.总体三种肿瘤的死亡率极低,且均随着年龄升高而升高.[结论] 2004～2011年间上海市卢湾区户籍人群常见妇科恶性肿瘤的发病率与死亡率较低,有一定程度的波动.高龄者是高危发病人群.发病趋势年轻化,尤其是宫颈癌的发病与死亡均有提前趋势,亟需采取有效防治措施.     

中国女性生殖系统肿瘤发病率和死亡率分析

目的:了解1990-2019年中国女性生殖系统肿瘤流行情况及趋势分析。方法:利用2019年全球疾病负担数据库,分析不同年龄组和不同年份女性生殖系统肿瘤的发病率和死亡率,并对1990-2019年女性生殖系统肿瘤的发病率和死亡率趋势进行分析。结果:2019年,女性生殖系统肿瘤发病顺位从高到低依次为宫颈癌(7.72/10万)、子宫体癌(4.69/10万)和卵巢癌(3.20/10万)。死亡顺位从高到低依次为宫颈癌(3.76/10万)、卵巢癌(2.05/10万)和子宫体癌(0.86/10万)。宫颈癌在15岁年龄组开始出现发病和死亡病例,子宫体癌在20岁年龄组开始出现发病和死亡病例,卵巢癌在5岁年龄组开始出现发病和死亡病例。在大部分年龄组范围内,宫颈癌的发病率和死亡率大于子宫体癌和卵巢癌,子宫体癌的发病率大于卵巢癌,但卵巢癌死亡率大于子宫体癌。1990-2019年,无论发病率和标化发病率,宫颈癌、子宫体癌和卵巢癌均有升高趋势。宫颈癌和卵巢癌死亡率呈升高趋势,子宫体癌无明显变化。调整了年龄结构后,宫颈癌和子宫体癌标化死亡率呈降低趋势,卵巢癌升高趋势相对降低。与全球平均水平比较,我国女性宫颈癌、子宫体...     

1972～2000年上海市长宁区恶性肿瘤发病趋势

[目的]对上海市长宁区居民1972～2000年的肿瘤发病资料进行统计分析,了解各种肿瘤的发病情况及变化趋势.[方法]病例按照国际疾病分类(ICD-9)进行编码.根据人口普查资料中的性别、年龄构成采用内插法和外推法估算各年的年龄组平均人口数.分析1972～2000年恶性肿瘤发病趋势,标化率采用世界标准人口进行计算.发病率年变化百分比用对数直线回归法估计,并用病例数加权.[结果]1972～2000年间,男性所有部位肿瘤标化发病率从260.46/10万降至205.35/10万,女性从185.26/10万降至165.14/10万.其中,男女性食管癌和女性宫颈癌的发病率下降幅度最大,约为50%,胃癌和肝癌的发病率也呈明显的下降趋势.但男女性结肠癌、胆道癌,男性前列腺癌,女性子宫体癌、肾癌、非霍奇金淋巴瘤的发病率上升很快,上升幅度达100%及以上.男性直肠癌、男性肾癌、女性乳腺癌、卵巢癌的发病率亦呈明显的上升趋势.[结论]1972～2000年间上海市长宁区恶性肿瘤的发病率发生较大变化,有升有降,上述发病率的变化趋势提示除了诊断水平和登记情况的改善外,居民生活方式的改变和其它环境暴露因素的变化可能起着重要作用,需进一步进行流行病学研究,明确危险因素,提出有针对性的预防措施.     

中国2009年宫体癌发病和死亡分析

[目的]分析我国2009年宫体癌发病和死亡情况,为宫体癌防治提供科学依据。[方法]收集和整理《2012全国肿瘤登记年报》收录的全国72个肿瘤登记地区2009年宫体癌发病和死亡资料,分析其发病和死亡数、构成比、顺位、粗率、标化率、0～74岁累积率和截缩率(35～64岁)等指标。[结果]2009年宫体癌发病数为2916例,发病粗率和世标率分别为6.90/10万和4.70/10万。城市和农村地区世标率分别为5.53/10万和2.79/10万,城市发病率高于农村。发病率前3位地区依次为广东中山市、江苏连云港市和北京市,其世标率分别为9.94/10万、8.99/10万和7.90/10万,均为城市和经济发达地区。后3位依次为江苏盱眙县、山西阳城县和浙江海宁市,其世标率分别为0、0.43/10万和1.17/10万,均为农村地区。2009年宫体癌死亡病例数为642例,死亡粗率和世标率分别为1.52/10万和0.96/10万,城市和农村地区世标率分别为0.98/10万和0.90/10万,城市死亡率略高于农村。死亡率前3位地区依次为江苏盱眙市、河南西平县和山东汶上县,其世标率分别为5.28/10万、3.70/10万和3.63/10万,均为农村地区。宫体癌年龄别发病和死亡趋势不同,发病高峰年龄为55～59岁年龄组,而死亡高峰年龄为80～84岁年龄组。[结论]2009年宫体癌发病居国内较高水平,尤其是城市和经济发达地区,而农村地区死亡率较高,应加强宫体癌的防治工作。     

中山市30年宫体癌发病趋势分析

目的探讨1970～1999年期间中山市宫体癌发病状况及趋势,为中山市宫体癌防治提供科学依据.方法收集、整理中山市1970～1999年期间肿瘤登记资料中的宫体癌发病资料,统计分析其发病数、发病粗率、中国与世界标化发病率等指标.结果1995～1999年期间中山市宫体癌发病租率、中国与世界标化发病率分别为7.45/105、6.54/105、8.22/105,且1970～1999年期间尤其是1994～1999年其发病率具有明显上升趋势.结论与西方发达国家相比,虽然中山市宫体癌发病率处于较低水平,但与同期中国试点市、县相比,则处于较高水平,提示中山市应加强宫体癌的防治.     

上海市2006-2008年原发性肝癌发病及死亡资料分析

目的:分析上海市2006-2008年原发性肝癌的发病和死亡数据.方法:根据上海市肿瘤登记处积累的原发性肝癌发病和死亡资料,统计和分析原发性肝癌粗发病率和粗死亡率、年龄别发病率和死亡率、世界标化发病率和死亡率等指标.结果:2006-2008年,上海市新发肝癌病例共11 972例,死亡合计10 669例;各年份原发性肝癌的标化发病率分别为15.59/10万、14.87/10万和14.56/10万,标化死亡率分别为13.85/10万、13.00/10万和12.21/10万.发病率和死亡率均随年龄增长而上升,有郊区高于市区和男性高于女性的特点.结论:2006-2008年,上海市原发性肝癌的发病率和死亡率均呈逐年下降趋势.     

深圳市2005~2014年宫颈癌发病趋势分析

摘 要：［目的］ 探讨2005~2014年深圳市宫颈癌的发病趋势,为制定和评价深圳市宫颈癌防治策略提供参考。［方法］ 根据深圳市肿瘤发病登记处收集的2005～2014年宫颈癌发病数据和相应年份的人口资料,计算宫颈癌发病粗率以及标准化人口年龄调整的发病率（中国人口标化率和世界人口标化率）,利用Joinpoint软件进行趋势分析。［结果］ 2005~2014年深圳市肿瘤登记处共登记宫颈癌5350例,粗发病率为12.22/10万,中国人口标化率为11.96/10万,世界人口标化率为14.76/10万。从时间趋势上看,宫颈癌发病率呈上升趋势,粗发病率从2005年的8.03 /10万上升至2014年的14.97 /10万,APC为4.76%（Z=2.38,P<0.05）;从不同户籍类型居民看,常住户籍居民粗发病率呈下降趋势,APC为-5.00%（Z=-2.19,P=0.06）,常住非户籍人口粗发病率呈上升趋势,APC为9.55%（Z=4.19,P<0.01）。10年间深圳市女性宫颈癌平均发病年龄呈上升趋势;25岁以上女性中宫颈癌粗发病率随着年龄的增长而上升,55岁年龄组发病率达到高峰,为50.34/10万,随后发病率呈下降趋势。［结论］ 宫颈癌仍然是深圳女性常见的恶性肿瘤之一,需加强常住居民,尤其是常住非户籍居民的宫颈癌筛查工作。     

林州市1985～2004年贲门癌流行趋势分析

[目的]探讨1985～2004年林州市贲门癌流行动态。[方法]对1985～2004年的贲门癌中国标化发病率和标化死亡率进行了分析。[结果]男女贲门癌中国标化发病率分别为35.47/10万～52.94/10万和16.31/10万～27.18/10万;男女贲门癌中国标化死亡率分别为23.85/10万～41.14/10万和10.90/10万～21.62/10万。男性贲门癌发病率、死亡率明显高于女性。贲门癌发病率高年龄组呈缓慢下降趋势。[结论]1985～2004年林州市贲门癌发病率和死亡率呈缓慢下降趋势。但贲门癌死亡各年龄组均呈下降趋势。     

1999～2008年深圳市宫颈癌发病趋势分析

[目的]分析深圳市宫颈癌发病趋势及变化原因,为深圳市宫颈癌防治提供科学依据。[方法]根据深圳市肿瘤发病登记处收集的1999～2008年的宫颈癌病例资料和相应年份的人口资料,分别计算各年龄组的年龄别发病率,并采用直接法计算世界人口调整发病率,利用Join-point模型进行趋势分析。[结果]1999～2008年深圳市肿瘤登记处共登记宫颈癌病例2103例,宫颈癌发病率呈上升趋势,世界人口调整发病率从1999年的1.04/10万上升至2008年的18.31/10万。相对于1999～2005年,2006～2008年各年龄组的发病率均呈上升趋势,上升幅度最高依次为25～30岁和30～35岁年龄组,上升幅度依次为423.46%和370.47%,且发病高峰由55～60岁前移至50～55岁年龄段。[结论]宫颈癌已成为深圳市近年来最常见、增幅最大的恶性肿瘤之一,其预防与控制应成为深圳市肿瘤控制计划制定和实施的重点之一,宫颈癌的筛查年龄应提前至35岁以前。     

Cancer incidence trends in Urban Shanghai, 1972-1989

Incidence data pertaining to more than 250,000 cancer cases diagnosed during the years 1972-1989 among residents of urban Shanghai, China, were analyzed to determine the relative importance of the various malignancies and to discover changes over time. In the most recent 3-year period, lung cancer was the most frequent cancer among men (57.0 per 100,000 person-years, age-adjusted world standard), followed by cancers of the stomach (50. 1), liver (29.6), esophagus (13.3), colon (11.2) and rectum (9.4). Among women, breast cancer leads (25.1), followed by cancers of the stomach (23.2), lung (18.8), liver (10.9), colon (10.2) and rectum (7.3). The most impressive increases in incidence rates from 1972-74 to 1987-89 were observed for cancers of the gallbladder (119% and 101% among men and women, respectively), colon (85% and 78%), and brain and other nervous system (71% and 60%). In addition, increases of 20-50% occurred for cancers of the pancreas, male lung, female breast, corpus uteri, kidney, and for non-Hodgkin's lymphoma. Rates declined notably for cancers of the esophagus (-54% and -53%), cervix uteri (-86%), and to a lesser extent (10-20%) cancers of the male stomach and liver. These observed trends can be explained only partly by improvements in cancer diagnosis and completeness of the cancer registry, and most likely reflect changes in the prevalence of risk factors in this population.     

Cancer incidence trends in urban shanghai, 1972-1994: an update.

Incidence rates for a number of cancers in urban Shanghai, China, have been changing markedly. Herein we update the trends using population-based data from the Shanghai Cancer Registry for 1972-1994. During 1993-1994, cancers of the lung, stomach, and liver were the 3 leading forms among men, with age-adjusted (world standard) incidence rates of 50.9, 39.2, and 26.5 per 100,000 person-years, respectively, followed by cancers of the colon (12.4) and esophagus (10.0). Among women, cancers of the breast (27.5), stomach (19.1), and lung (17.7) were the most common tumors, followed by cancers of the colon (11.3) and liver (9.4). Over the 23-year period, the rate for all cancers combined, excluding non-melanoma skin cancer, decreased from 247.5 to 215.2 among men and from 173.6 to 154.0 among women. However, trends for individual forms of cancer varied considerably. Rates doubled for cancers of the colon and biliary tract in both sexes, and they increased substantially for cancers of the brain and nervous system, kidney, pancreas, prostate, corpus uteri, female breast, and ovary, and for non-Hodgkin's lymphoma. Rates for cancers of the lung and rectum changed little. Rates declined by at least one-half for cancers of the esophagus and cervix, with notable decreases also for cancers of the stomach and liver. Some of these trends may reflect variations in diagnostic or screening practices, although changes in lifestyle and other environmental exposures are likely to play important roles. Further epidemiologic research in China is needed to identify risk factors influencing the cancer incidence trends.     

武威市女性生殖系统恶性肿瘤发病率分析

  目的 探讨女性生殖系统恶性肿瘤的流行特征，为病因假说提供线索，并对女性生殖系统恶性肿瘤预防提供依据。方法 通过建立恶性肿瘤登记报告制度获取发病资料，按《中国恶性肿瘤登记工作指导手册》介绍的方法计算中国人口调整率、世界人口调整率、世界人口截缩调整率、0～74岁累积发病率等统计指标。结果 2001年至2005年女性生殖系统恶性肿瘤年平均粗发病率为18.66／10万，中国人口调整率为15.46／10万，世界人口调整率为18.93／10万，世界人口截缩调整率为45.63／10万，0 ~ 74岁累积率为2.14 %。发病率有随年龄的增长而升高的趋势。女性生殖系统恶性肿瘤按发病率高低依次为子宫颈癌、卵巢及附件癌、子宫体癌、其他女性生殖器官癌、不明部位子宫癌。结论 武威市女性生殖系统恶性肿瘤发病呈上升趋势。     

Cancer survival in Seoul, Republic of Korea, 1993-1997

The Seoul cancer registry was established in 1991. Cancer is a notifiable disease, and registration of cases is done by passive and active methods. The registry contributed survival data for 56 cancer sites or types registered during 1993-1997. Follow-up information has been gleaned predominantly by passive methods with median follow-up ranging between 5-82 months for various cancers. The proportion with histologically verified diagnosis for different cancers ranged between 23-99%; death certificates only (DCOs) comprised 0-67%; 33-100% of total registered cases were included for survival analysis. The top-ranking cancers on 5-year age-standardized relative survival rates were testis and placenta (95%), thyroid (93%), non-melanoma skin (93%), corpus uteri (79%), renal pelvis (77%), cervix (76%), Hodgkin lymphoma (75%), breast (74%) and prostate (74%). Five-year relative survival by age group showed a decreasing trend with increasing age groups for cancers of the small intestine, colon, gall bladder, cervix, corpus uteri, ovary, kidney, urinary bladder and thyroid, or was fluctuating for other cancers.     

Decreasing Trend in the Incidence of Stomach Cancer in Mumbai,India, during 1988 to 1999

The time trend in incidence of stomach cancer in males and females in Mumbai, India during 1988 to 1999 was ‍estimated using data collected by the Bombay Population-based Cancer Registry. During the 12-year period, a total ‍of 3657 stomach cancer cases (3.9% of all cancers) were registered by the Bombay Population-based Cancer Registry ‍of which 2467 (5.1% of all male cancers) were in males and 1184 (2.6% of all female cancers) in females. For evaluation ‍of the trend, we applied a linear regression model based on the logarithm of the observed incidence rates. The annual ‍percentage changes were also computed for the incidence rates for evaluating the time trend. A statistically significant ‍decreasing trend in the overall age-adjusted incidence rates of stomach cancer was observed during the period 1988 ‍to 1999, with an yearly decrease of 4.44% in males and 2.56% in females. This decrease was most striking in males ‍in the age groups 40-59 and 60+, and in females only in the age group 40-59. The probability estimates indicated that ‍one out of every 92 men and one out of every 187 women will contract a stomach cancer at some time in their whole ‍life and 95% of the chance is after his or her 40th birthday. The decreasing trend in the age-adjusted incidence rates ‍of stomach cancer in both the sexes indicates that there is a critical change in the etiology of this cancer. The findings ‍may provide clues relating to various life-style and environmental changes impacting on stomach cancer incidence.     

Long-term survival experience of female patients with genital cancer

Survival analyses of patients with cancer of the cervix uteri, corpus uteri or ovary registered at Cambridge in 1960-1979 show that, although the long-term survivors had mortality rates similar to those of a normal age-matched population and might therefore be considered 'statistically cured', their risk of dying from their original cancer was still much higher than normal. Death rates from other cancers were slightly increased in cervix patients but not in corpus and ovary. At all three sites there was no evidence that deaths from non-malignant causes were increased. Only in cancer of the ovary was survival significantly better for patients registered in 1970-1979 than for patients registered in 1960-1969.     

Incidence trends for cancers of the breast,ovary, and corpus uteri in urban Shanghai, 1972–89

Incidence data from the Shanghai (People's Republic of China) Cancer Registry were used to assess the temporal trends of three major female cancers during 1972–89. Rates for cancers of the breast, corpus uteri and, to a lesser extent, ovary rose over the study period. The increases in breast and ovarian cancer were most pronounced among women under age 50, whereas those for corpus uteri cancer were restricted generally to those aged 55 to 69 years. When considered by cohort year of birth, risk of breast and ovarian cancers rose among women born since 1925 and 1935, respectively, but little evidence of cohort effect was apparent for corpus uteri cancer. Potential explanations for these patterns are explored.     

Cancer survival in Incheon, Republic of Korea, 1997-2001

The Incheon cancer registry was established in 1997. Cancer is not a notifiable disease, hence registration of cases is done by active methods. The registry contributed survival data for 42 cancer sites or types registered during 1997-2001. The follow-up information has been obtained predominantly by passive methods, with median follow-up ranging between 1-44 months for various cancers. The proportion with histologically verified diagnosis for different cancers ranged between 16-100%; death certificates only (DCOs) comprised 0-51%; 49-100% of total registered cases were included for the survival analysis. The top-ranking cancers on 5-year age-standardized relative survival rates were testis (98%), thyroid (90%), ureter (87%), adrenal gland (86%), nonmelanoma skin (83%), corpus uteri (82%), Hodgkin lymphoma (81%), breast and cervix (74%). Five-year relative survival by age group showed a decreasing trend with increasing age groups for cancers of the stomach, small intestine, colon, gall bladder, larynx, lung, breast, cervix and ovary, and was fluctuating for other cancers.     

Cervical Adenocarcinoma and Squamous Cell CarcinomaIncidence Trends among Tunisian Women

Introduction: Uterine cervix cancer is an important public health problem in Tunisia. In this study, we reporttrends in the incidence of adenocarcinoma and squamous cell carcinoma of the cervix uteri in the central regionof Tunisia during 1993-2006. Design: Data were obtained from the Cancer Registry of the Center of Tunisiawhich registers invasive cancer cases by active methods. Five-year age-specific rates, crude incidence rates (CR),world age-standardized rates (ASR), percent change (PC) and annual percent change (APC) were calculatedusing annual population data. Results: Among all women cancers, cervix uteri cancer accounted for 5.9% andranked the fourth during the study period with an ASR of 6.9 per 100,000. The ASRs decreased notably with anAPC of -6.7% over the whole period. However, incidence rates of adenocarcinomas have increased during thelast years (APC: +14.4%). Conclusion: The introduction of cytological screening programs has led to a markeddecrease of the incidence rates of cervix uteri cancer among Tunisian women. The data underline the fact thatthe population-based cancer registry is an indispensable tool for providing data for planning and evaluation ofprograms for cancer control.