慢性充血性心力衰竭患者甲状腺激素的变化及意义

目的：探讨充血性心力衰竭(CHF)患者甲状腺激素的改变及其临床意义。方法：用放免法检测68例慢性充血性心衰竭患者血清T3、T4、rT3、FT3、FT4及TSH的变化,并与56例正常对照组进行比较。结果：CHF组T3明显低于正常,rT3显著升高,且CHF组随心衰的加重,T3逐渐降低,rT3逐渐升高。结论：甲状腺激素水平的变化可作为判断CHF严重程度的指标,并对其治疗及预后有一定指导意义。     

甲状腺功能对充血性心力衰竭患者预后及左心室功能的影响

目的　探讨血清甲状腺激素水平与充血性心力衰竭 (CHF)患者预后及左心室功能的关系。方法　采用前瞻性研究方法 ,动态检测 30例CHF患者及 30例非CHF患者的总T3 (TT3 )、总T4(TT4)、游离T3 (FT3 )、游离T4(FT4)及促甲状腺激素 (TSH) ,同时采用超声心动图动态检测CHF患者的左心室功能。结果　CHF组TT3 及FT3 明显低于对照组 (P <0 .0 5 ,P <0 0 1) ,严重者TT4也降低 ,CHF患者发病初期预后不良组与好转组血清TT3 ,FT3 ,TT4均有不同程度降低 ,TSH正常 ,两者差异无显著性 (P >0 6 0 5 ) ;病后第 4周预后不良组血清TT3 ,TT4,FT3 明显低于好转组 ;相关分析表明 ,射血分数 (EF)与TT3 ,FT3 呈正相关 (P <0 0 5 ) ,EF与TSH呈负相关。结论　充血性心力衰竭患者血清甲状腺激素的代谢发生了明显变化 ,可作为判断病情、预后的重要指标。     

充血性心力衰竭患者甲状腺激素异常变化及其临床意义

目的探讨充血性心力衰竭患者甲状腺激素异常变化及临床意义.方法采用放射免疫法检测了64例充血性心力竭(CHF)患者及28例正常对照者血浆三碘甲状腺原氨酸(T3)四碘甲状腺原氨酸(T4)、反三碘甲状腺原氨酸(rT3)及促甲状腺激素(TSH)的浓度,并对CHF患者作了为期6周的预后观察.结果 CHF患者T3降低,rT3升高,而T4、TSH正常.而且T3越低,T3/rT3比值越小,心功能愈差,预后越差.结论 CHF患者T3 、尤其是T3/rT3比值的变化可作为病情程度及短期预后的判断指标.     

老年充血性心力衰竭患者血清甲状腺激素的变化及其临床意义

目的：探讨充血性心力衰竭（CHD患者血清甲状腺激素及促甲状腺激素水平的变化及其临床意义。方法：用放射免疫法测定60例CHF患者血清三碘甲状腺原氨酸（T3）、四碘甲状腺原氨酸（T4）、游离T3（FT3）、游离T4（FT4）、促甲状腺激素（TSH）的变化，并与38例正常对照组进行比较。经治疗后54例好转，其中46例复查上述参数。结果：轻度CHF患者甲状腺激素无明显变化；重度CHF患者T3明显降低，心衰越重变化越明显，T4、FT3、FT4、TSH无明显变化；心衰减轻后T3明显升高。结论：血清T3水平的改变对判断CHF严重程度、治疗效果和预后有一定的指导意义。     

慢性心力衰竭患者甲状腺激素水平变化的临床观察

目的探讨慢性充血性心力衰竭患者(CHF)甲状腺激素水平的变化及临床意义。方法采用放射免疫法测定30例体检正常者和50例慢性心力衰竭患者心衰治疗前后的血浆三碘甲状腺原氨酸(T3)、甲状腺素(T4)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)及促甲状腺素(TSH)水平。比较两组间的差异,并对CHF患者进行亚组分析。结果CHF组T3、FT3较对照组下降,且慢性心衰组随着心力衰竭的加重,T3、FT3水平逐渐减低;T4、FT4、TSH两组间比较无显著差异,抗心衰治疗后T3、FT3水平明显上升(P<0.05)。慢性心衰组患者血清中T3、FT3的水平与心衰程度呈负相关关系。结论CHF患者甲状腺激素水平的变化,对判断其心功能损害程度和预后具有一定的临床意义。     

老年充血性心力衰竭患者甲状腺激素水平研究

目的：探讨老年充血性心力衰竭患者血清甲状腺激素水平的变化。方法：采用放射免疫法测定30例体检正常者及60例老年充血性心力衰竭患者心衰期和心衰纠正后的血清甲状腺激素（TT3、TT4、rT3)水平和促甲状腺激素（TSH）水平，并进行比较。结果：体检正常者、老年充血性心力衰竭心衰期及心率纠正后其血清TT4、TT3、rT3、FT4 I含量间的差别均有显著性意义（P＜0．05）。结论：老年充血性心力衰竭的心衰期血清甲状腺激素分泌减少，而且通过rT3途径更有效地减少机体对氧和能量的消耗。     

慢性心力衰竭患者甲状腺激素的变化及意义

目的:探讨慢性心力衰竭患者甲状腺激素(T3、T4、FT3、FT4、TSH)水平的变化及意义。方法:用放免法测定60例慢性充血性心力衰竭患者(心衰组)抗心衰治疗前后的血清T3、T4、FT3、FT4、TSH水平,与46例健康体检者(对照组)比较。结果:心衰组T3、FT3较对照组下降(P<0.05或P<0.01),T4、FT4仅在重度心衰时下降(P<0.05),而TSH在两组间无明显差异;抗心衰治疗后,T3、FT3水平明显上升(P<0.05)。结论:T3、FT3可作为反映慢性充血性心力衰竭严重程度、治疗效果和预后的一项判定指标。     

各类肝硬化患者甲状腺激素检测的意义

目的 探讨肝硬化患者血清中三碘甲腺原氨酸(T3)、甲状腺激素(T4)、游离T3(FT3)、游离T4(FT4)、促甲状腺激素(TSH)及反T3(rT3)测定的临床意义.方法 采用磁酶免法测定T3、T4、TSH、FT3、FT4、rT3.结果 与对照组相比,肝炎后肝硬化患者血清T3、FT3浓度明显下降(P＜0.01),rT3、FT4浓度明显增高(P＜0.01,P＜0.05);酒精性肝硬化患者血清中T3、FT3浓度明显降低(P＜0.01),TSH、rT3浓度明显升高(P<0.01).结论 联合检测T3、T4、FT3、FT4、RT3、TSH在不同种类肝硬化的鉴别诊断中有一定的临床意义.     

充血性心力衰竭患者血清甲状腺激素检测及其临床意义

目的探讨充血性心力衰竭（CHF）患者血清甲状腺激素水平的变化及临床意义。方法采用化学发光法测定80例NYHA分级Ⅱ-Ⅳ级CHF患者（CHF组）和80例健康体检者（对照组）的血清FT3、FT4及TSH水平，并进行对比分析。结果与对照组相比，观察组血清FT3水平明显降低，差异有统计学意义p〈0．01，而血清FT4及TSH水平无明显变化。心功能Ⅱ-Ⅳ级CHF患者的血清FT3水平依次降低，差异有统计学意义，均p〈0．01，而血清FT4及TSH水平下降不明显。结论CHF患者FT3水平降低与心衰严重程度有关，检测FT3水平可用于其病情评估和预后判断。     

老年慢性充血性心力衰竭患者甲状腺素水平的变化研究

目的:探讨老年慢性充血性心力衰竭(CHF)患者甲状腺素水平的变化及临床意义。方法:应用磁分离酶联免疫测定法对86例老年慢性充血性心力衰竭患者进行心功能分级并分类。对不同心功能状态患者的血清FT3、FT4、TSH、TGA(抗甲状腺球蛋白抗体)、TM A(抗甲状腺微粒体抗体)进行检测,并与健康组对照,其中对34例抗心衰治疗后患者的血清FT3、FT4、TSH、TGA、TM A进行检测,并与抗心衰治疗前对照。结果:老年心衰组心功能Ⅲ级及Ⅳ级患者,血清游离T3明显下降,与健康组对照有显著性差异;抗心衰治疗前后血清游离T3在两组间亦有显著性差异。结论:甲状腺激素的变化可评估老年慢性心力衰竭的严重程度、治疗效果及预后。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.