巴特日七味丸联合姜黄消痤搽剂治疗面部寻常性痤疮的疗效观察

目的观察巴特日七味丸联合姜黄消痤搽剂治疗面部寻常性痤疮的临床疗效。方法采用随机分组,治疗组口服巴特日七味丸,外涂姜黄消痤搽剂治疗,对照组单独使用姜黄消痤搽剂外涂治疗,连续4周。结果治疗组痊显率为92．9％,对照组痊显率为76．2％,两组疗效比较差异有统计学意义（P〈0．05）,治疗组优于对照组。结论巴特日七味丸联合姜黄消痤搽剂治疗面部寻常性痤疮可明显提高疗效。     

消痤汤联合水调散治疗寻常痤疮临床报道

目的:观察消痤汤配合水调散外敷治疗寻常痤疮的疗效。方法:选取2014年1月—2015年1月来我院接受治疗的痤疮患者129例,随机分为治疗组和对照组。治疗组65例,采用消痤汤配合外用水调散治疗,并对比两组的起效时间和治疗效果。结果:治疗组患者的皮损开始减小时间和皮损减小至稳定时间均明显快于对照组(P0.05),总有效率达到90.77%,治愈显效率达到75.38%,对照组总有效率73.44%,治愈显效率50.00%,两组治愈显效率有非常显著性差异(P0.01),总有效率差异有显著性(P0.05)。结论:消痤汤配合水调散外敷治疗寻常痤疮能明显缩短痤疮消退时间,提高临床治疗效果,值得临床推广。     

果酸联合枇杷清肺饮加减方治疗寻常痤疮的临床疗效观察

目的:探讨寻常痤疮患者运用果酸联合枇杷清肺饮加减方治疗的临床价值。方法:从我院2014年3月至2016年3月选取82例寻常痤疮患者进行非盲法随机分组试验,联合治疗组(Ⅰ组)及对照组(Ⅱ组)各41例,Ⅰ组接受果酸与枇杷清肺饮加减方治疗,Ⅱ组单纯接受果酸涂抹,对两种方案的疗效做评估。结果:治疗前,两组的炎性皮损评测结果经分析,严重程度无显著性差异(P0.05),Ⅰ组接受治疗后的总有效率为95.1%,与Ⅱ组的78.0%相比显著提高(P0.05)。结论:对寻常痤疮患者实施果酸与枇杷清肺饮加减方联合治疗,药效显著、安全,利于患者皮损的改善,值得加以推广。     

复方蛇草汤对寻常痤疮的治疗效果观察

目的分析复方蛇草汤对寻常痤疮的治疗效果。方法选取本院寻常痤疮患者40例,收治时间为2012年3月至2014年5月期间,并将寻常痤疮患者随机分为两组(观察组和对照组),每组各有20例患者,对照组采用维胺酯胶囊治疗,观察组采用复方蛇草汤治疗,比较两组寻常痤疮患者治疗后的总有效率。结果观察组寻常痤疮患者在总有效率的比较中显著优于对照组(P0.05)。结论给予寻常痤疮患者采用复方蛇草汤治疗,不仅能改善患者的临床症状,而且还能增加治疗后的总有效率。     

夫西地酸乳膏联合果酸治疗寻常型痤疮的效果观察

目的观察夫西地酸乳膏联合果酸治疗寻常型痤疮的临床疗效。方法选取2014年3月至2014年8月河南省人民医院皮肤科门诊收治的40例轻中度寻常型痤疮患者,随机分为治疗组和对照组,各20例。治疗组给予夫西地酸乳膏联合果酸治疗,对照组仅给予夫西地酸乳膏治疗。两组患者均连续治疗9周,评价疗效及安全性。结果治疗组痊愈率及显效率高于对照组,差异有统计学意义(P<0.05)。两组患者不良反应发生率差异无统计学意义(P>0.05)。结论果酸联合夫西地酸乳膏治疗寻常型痤疮的疗效及安全性均较高,值得临床推广应用。     

自拟三黄消痤饮治疗寻常型痤疮53例临床观察

目的观察三黄消痤饮治疗寻常型痤疮的临床疗效。方法对53例寻常型痤疮患者用三黄消痤饮连续治疗3月，疗程结束后复查。结果痊愈24例。显效16例，有效8，无效5例。3月后随访，寻常型痤疮复发9例，总有效率为90．57％，复发率为16．98％。结论三黄消痤饮治疗寻常型痤疮疗效显著，愈后稳定，复发率较低。     

消痤方治疗寻常痤疮325例临床观察

[目的]观察清热解毒、活血化瘀中药复方消痤方治疗寻常型痤疮的疗效。[方法]将446例寻常痤疮患者随机分为两组,治疗组(325例)采用自拟消痤方(主要由银花、白花蛇舌草、蒲公英、野菊花、黄芩、桑白皮、丹参、生地、桃仁、赤芍、皂刺等中药组成)内服配合痤疮水(含3％甲硝唑、2％红霉素)外搽治疗,对照组(121例)采用异维A酸口服配合痤疮水外搽治疗,观察两组治疗前后面部各种皮损的数目及药物副作用。[结果]两组疗效经Ridit分析显示,治疗组临床疗效优于对照组(u=2.204 6,P<0.05);消痤方有改善面部皮损的作用(与治疗前比较P<0.05),但与对照组比较无显著性差异(P>0.05);治疗组未见明显不良反应,对照组5例出现不同程度皮肤干燥、恶心、头晕等症状。[结论]消痤方是临床治疗痤疮的有效药物,其作用机制值得进一步探讨。     

维胺脂胶囊联合痤康王治疗寻常痤疮

目的观察维胺脂胶囊与痤康王联合治疗寻常痤疮的临床疗效和安全性。方法将门诊寻常痤疮患者随机分成两组,治疗组150例,用维胺脂胶囊50mg,3次/d口服,痤康王3次/d涂患处;对照组110例单用痤康王3次/d涂患处,疗程4周,观察疗效。结果治疗组总有效率82%,对照组总有效率70%,差异有统计学意义。结论维胺脂胶囊与痤康王联合治疗寻常痤疮疗效好,而且安全。     

桑丹消痤净面膜对寻常性痤疮患者性激素水平的影响

目的:评价桑丹消痤净面膜治疗寻常性痤疮的疗效及安全性,并观察其对痤疮患者性激素的影响.方法:86例Ⅰ～Ⅲ度寻常性痤疮患者随机分为桑丹消痤净面膜治疗组和5%过氧苯甲酰霜对照组,均治疗8周,评价其临床疗效,并观察桑丹消痤净面膜治疗前后患者血清中性激素的变化,同时以66例健康志愿者为对照.结果:桑丹消痤净面膜治疗总有效率为88.4%.对照组总有效率为72.1%,两组比较,差异有显著性(P＜0.05),无严重不良反应.男女寻常痤疮患者治疗前性激素水平与正常对照组比较有异常,治疗后男女寻常痤疮患者性激素治疗组LH、FSH、E2和T水平与正常组比较,无显著性差异(P＞0.05),寻常性痤疮组和对照组治疗后LH及FSH,两两比较,差异显著(P＜0.01).结论:桑丹消痤净面膜具有较好的临床效果,对性激素有调节作用.     

红蓝光照射联合西黄胶囊治疗面部中重度寻常痤疮的效果及对患者生活质量的影响

目的探讨红蓝光照射联合西黄胶囊治疗面部中重度寻常痤疮的效果及对患者生活质量的影响。方法选取鹤壁市人民医院收治的77例面部中重度寻常痤疮患者,随机分为两组,对照组38例,观察组39例,对照组予以西黄胶囊治疗,观察组给予西黄胶囊+红蓝光照射治疗,观察比较两组临床疗效及生活质量评分。结果观察组治疗总有效率为84.62%,高于对照组63.16%,差异有统计学意义(P<0.05);治疗后观察组生活质量评分高于对照组,差异有统计学意义(P<0.05)。结论红蓝光照射联合西黄胶囊治疗面部中重度寻常痤疮,效果显著,可有效提高患者生活质量。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.