倍他乐克治疗慢性充血性心衰的疗效观察

目的：探讨β受体阻滞剂在慢性充血性心力衰竭中的疗效。方法：选择38例慢性充血性心力衰竭患者,在常规应用强心、利尿、扩血管药物的基础上,加用β受体阻滞剂倍他乐克治疗2个月后观察心力衰竭患者心率、血压和心功能的变化。结果：应用倍他乐克后心力衰竭患者心功能分级显著改善,心率明显降低,收缩压和舒张压也显著降低。结论：在常规抗心力衰竭药物治疗基础上加用β受体阻滞剂可明显改善慢性心力衰竭患者的心功能,提高生活质量,延长患者寿命。     

倍他乐克在慢性充血性心力衰竭中的应用

目的:探讨β受体阻滞剂倍他乐克在慢性充血性心力衰竭中的疗效。方法:选择56例慢性充血性心力衰竭住院患者,随机分为治疗组和对照组,治疗组在常规应用强心、利尿、扩血管药物的基础上,加用β受体阻滞剂倍它乐克。结果:治疗3个月后治疗组心力衰竭患者心功能分级显著改善,心率明显降低,收缩压及舒张压也显著降低。结论:在常规抗心力衰竭药物治疗基础上加用β受体阻滞剂可明显改善慢性心力衰竭患者的心功能,提高生活质量,延长患者寿命。     

ACEI联合β受体阻滞剂治疗慢性心力衰竭患者的临床疗效分析

目的 探讨ACEI联合β受体阻滞剂治疗慢性心力衰竭患者的临床疗效.方法 选取60例慢性心力衰竭患者,随机分为对照组与观察组,对照组采用常规治疗,观察组采用在常规治疗基础上加用ACEI联合β受体阻滞剂治疗,对比分析2组疗效.结果 经过治疗后观察组在TEI指数、LVEF、SV、LVEDD改善显著优于对照组,差异有统计学意义(P<0.05),观察组治疗总有效率为90.00%,明显高于对照组,差异有统计学意义(P<0.05).结论 ACEI联合β受体阻滞剂治疗慢性心力衰竭患者有益于改善患者心功能,疗效显著,值得在临床应用中推广.     

倍他乐克对冠心病心力衰竭的治疗观察

目的探讨β-受体阻滞剂在治疗冠心病心力衰竭中的疗效。方法选择冠心病心力衰竭患者36例,在常规应用强心、利尿、扩血管药物治疗基础上,加用β-受体阻滞剂倍他乐克12.5～50mg/d6周,用自身对照比较治疗前后患者心率、血压、心胸比率,左心室射血分数的变化,评估其有效性和安全性。结果患者心率减慢、血压降低、心胸比率缩小,左室射血分数增加P<0.01,心功能明显改善。结论在常规抗心衰药物基础上加用β-受体阻滞剂倍他乐克不仅能有效地改善心功能状态,而且能逆转心脏扩大。     

美托洛尔治疗慢性充血性心力衰竭临床研究

目的评价美托洛尔治疗慢性心力衰竭的临床疗效及安全性。方法 120例慢性充血性心力衰竭患者除治疗原发性病因及诱因外随机分为对照组和治疗组。对照组采用常规抗心力衰竭:强心剂(地高辛)、利尿剂(速尿、氨体舒通)和扩血管药物(卡普托利)及对症辅助治疗;治疗组在常规治疗的基础上加用β受体阻滞剂(美托洛尔)治疗,2个月后观察心力衰竭患者心率、血压和心功能的变化心功能改善一级者为有效。结果应用美托洛尔后心力衰竭患者心功能分级显著改善,心率明显降低,收缩压和舒张压显著降低。结论β受体阻滞剂美托洛尔能显著改善心功能,提高患者生活质量及增加运动量。     

老年慢性充血性心力衰竭小剂量倍他乐克疗效观察

目的观察倍他乐克治疗老年慢性充血性心力衰竭的临床疗效和安全性。方法将60例病因不同的老年心衰患者随机分为两组,对照组按常规抗心力衰竭治疗,治疗组常规心力衰竭治疗加倍他乐克。结果两组治疗前后血压、心率明显降低,而治疗组改变较对照组更明显,P〈0.05。两组治疗前后心功能指标均有显著提高,但治疗组心功能改善明显优于对照组。结论对于老年慢性充血性心力衰竭小剂量应用β-受体阻滞剂倍他乐克,是一种安全有效的治疗方法,在临床上值得推广应用。     

卡维地络、倍他乐克治疗慢性心力衰竭的疗效比较

目的:对比卡维地洛和倍他乐克治疗两种不同类型的β-受体阻滞剂对慢性心力衰竭的临床疗效.方法:将60 例慢性心力衰竭患者在常规治疗心力衰竭基础上随机分为卡维地洛组(n=30 例)和倍他乐克组(n=30 例),随治6~12 个月观察两组治疗前后心率、左室射血分数(LVEF) 及心功能变化.结果:两组间治疗前、后,在心率及LVEF 方面.无统计学意义(P>0.05),但同组治疗前后有差异(P<0.05); 两组间有效率有差异(P<0.05).结论:卡维地络在LVEF 及心率方面比倍他乐克的优越性,卡维地洛在治疗慢性心力衰竭中安全有效,且有效率优于倍他乐克组.     

倍他乐克治疗慢性充血性心力衰竭疗效观察

目的：探讨倍他乐克在慢性充血性心力衰竭中的疗效。方法：选择56例慢性充血性心力衰竭患者,随机分为两组．治疗组在常规应用强心、利尿、扩血管药物的基础上,加用倍他乐克。2个月后观察患者心功能、心率的变化,评估其临床疗效。结果：应用倍他乐克后心力衰竭患者心功能分级显著改善,心率明显降低。结论：在常规抗心力衰竭药物治疗基础上加用倍他乐克可明显改善慢性心力衰竭患者的心功能。     

β受体阻滞剂治疗慢性心力衰竭20例疗效观察

目的观察β受体阻滞剂治疗慢性心力衰竭的疗效。方法将慢性心力衰竭患者40例随机分为对照组和观察组。对照组应用强心、利尿、扩血管药治疗;观察组在对照组治疗的基础上加用倍他乐克,1周后酌情加量至12.5 mg,2次/d,以后逐渐增至患者的最大耐受量。观察半年,比较2组治疗前后静息心率、心脏射血分数、心功能分级等临床指标变化,评估β受体阻滞剂的临床有效性和安全性。结果β受体阻滞剂在改善静息心率,改善心功能,降低病死率及住院率方面较对照组效果明显。结论β受体阻滞剂可明显改善心脏功能,提高患者生存质量,延缓心力衰竭进程。     

β受体阻滞剂治疗慢性心力衰竭疗效观察

目的观察β受体阻滞剂对心力衰竭的临床疗效。方法将入选患者随即分为两组。两组性别、年龄、病因及基础用药具有可比性。对照组给予强心利尿扩血管等常规治疗。治疗组在常规治疗的基础上,加服β受体阻滞剂（卡维地洛）,对治疗前后心率（HR）、血压（BP）、左室舒张末期内径（LVDD）、左室射血分数（LVEF）对比观察。结果治疗组较对照组心功能各项指标均明显好转。结论在常规强心、利尿、扩血管治疗顽固性心衰的基础上,加用β受体阻滞剂,能迅速缓解慢性心力衰竭急性加重期临床症状,缩短住院日程;长期用药能抑制心肌重塑,改善心功能,提高射血分数,降低病死率。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.