急性脑梗死血清C-反应蛋白的临床分析

目的观察急性脑梗死患者血清CRP在发病中的作用及临床意义.方法采用免疫比浊法对60例急性脑梗死患者的血清CRP水平进行动态观察(病程第1、7及14天),并与45例健康人进行比较.结果急性脑梗死患者血清CRP从病程第1天即升高(P＜0.01),至第7天达高峰,以后降低;重型患者明显高于轻、中型患者.结论血清CRP可能在急性脑梗死的发生、发展中起一定作用,并与病情严重程度呈正相关.     

急性脑梗死血清C-反应蛋白的临床研究

目的:研究急性脑梗死患者血清CRP在发病中的作用及临床意义。方法:采用免疫比浊法对120例急性脑梗死患者的血清CRP水平进行动态观察(病程第1、7及14天),并与90例健康人进行比较。结果:急性脑梗死患者血清CRP从病程第1天即升高,明显高于对照组(P<0.01),至第7天达高峰,以后降低;重型患者明显高于轻、中型患者。结论:血清CRP可能在急性脑梗死的发生、发展中起一定作用,并与病情程度呈正相关。     

急性脑梗死患者血清超敏C反应蛋白检测的临床意义

目的 观察急性脑梗死患者血清CRP在发病中的作用及临床意义. 方法采用免疫比浊法对65例急性脑梗死患者的血清CRP水平进行动态观察,并与30例健康样本进行比较.结果 急性脑梗死患者血清CRP从病程第1天即开始升高,至第7天达高峰,以后降低,重型患者明显高于中、轻型患者.结论 CRP水平的升高不仅能反映体内炎性系统反应的程度,也能反映脑卒中的严重程度.     

急性脑梗死患者血清C反应蛋白水平的变化及其临床意义

目的观察急性脑梗死患者血清C反应蛋白的变化规律,探讨C反应蛋白在急性脑梗死发病中的作用及临床意义。方法采用免疫比浊法对46例急性脑梗死患者血清C反应蛋白水平进行动态观察（病程第1、7及14d）,并与40例健康人进行比较。结果急性脑梗死患者血清C反应蛋白从病程第1天即升高,明显高于对照组（P〈0.01）,第7天达到高峰,以后降低;重症患者明显高于轻、中型患者。结论血清C反应蛋白可能在急性脑梗死的发生、发展中起一定的作用,并与病情程度呈正相关。     

丁苯肽对急性脑梗死患者血清TNF-α、CRP和神经功能缺损程度评分的影响

目的观察丁苯肽对急性脑梗死的早期治疗作用。方法80例急性脑梗死患者随机分为丁苯肽治疗组及常规对照组各40例,分别采臭患者治疗前和治疗后第14天外周血标本,测定血清肿瘤坏死因子（TNF-α）和C-反应蛋白（CRP）水平,同时对患者治疗前及治疗后第7、14天进行神经功能缺损程度评分。结果治疗组和对照组第14天血清TNF-α、CRP水平较治疗前降低（P〈0．01）,且治疗组较对照组显著降低（P〈0．01）;第7、14天神经功能缺损程度评分治疗组较对照组有明显改善（P〈0．01）。结论丁苯肽对急性脑梗死的早期有显著治疗作用。     

C-反应蛋白水平与脑梗死病情及预后的相关关系

目的 探讨脑梗死患者血清C-反应蛋白水平与病情严重程度及预后的相关关系。方法 测定92例病程7d内的脑梗死患者入院当时和治疗2wk后血清CRP含量，观察脑梗死灶不同面积含量变化，并对其神经功能缺损进行标准评分。同时选取96例健康体检人员血清CRP含量进行对照。结果 （1）脑梗死患者血清CRP含量明显高于健康对照组（P〈0．05）；（2）脑梗死患者血清CRP含量变化与梗死灶大小及神经功能缺损程度关系密切。结论 CRP水平是临床评价脑梗死严重程度和预后的一个重要的生物学指标。     

依达拉奉对急性脑梗死患者高敏C反应蛋白的影响

目的探讨依达拉奉对急性脑梗死（ACI）患者血清高敏C反应蛋白（CRP）含量变化的影响。方法90例ACI患者随机分为两组。治疗组45例，入院后立即给予依达拉奉30mg，溶入250ml生理盐水静脉滴注，每日2次，疗程14d，其他用药同对照组。对照组45例，只给予基础治疗。应用散射免疫比浊法检测治疗前、治疗后7d、14d的血清CRP水平，并对神经功能缺损进行标准评分。结果两组CRP水平在梗死后第7天最高，随后逐渐降低。治疗组在治疗前，第14天血清CRP水平和治疗前的神经功能缺损评分与对照组患者比较差异无统计学意义（P〉0．05），治疗后第7天治疗组CRP水平低于对照组（P〈0．05）；但第7天、第14天治疗组神经功能缺损评分明显低于对照组（P〈0．01）。结论依达拉奉明显降低ACI患者血清CRP水平，有利于减轻炎症反应，改善脑梗死部位缺血缺氧和缺损神经功能．     

急性脑梗死患者血清C反应蛋白水平的观察分析

目的:探讨急性脑梗死患者血清CRP的变化规律及临床意义.方法:采用免疫速率散射比浊法对90例急性脑梗死患者的血清CRP进行动态观察,分别在发病后第1、7、14 d测定.并与80例健康人作为对照.结果:急性脑梗死患者血清CRP从发病后第1 d开始升高,1周达高峰,随后下降,其值明显高于对照组(P<0.01).结论:血清CRP可能在急性脑梗死的发生、发展中起一定作用,动态测定血清CRP可作为估计脑梗死患者严重程度及预后的指标.     

急性脑梗死患者高压氧治疗前后检测血清NSE的临床价值

目的：探讨急性脑梗死患者高压氧治疗前后血清神经元特异性烯醇化酶（NSE）的动态变化及临床价值。方法：将急性脑梗死患者88例随机分为高压氧治疗组（44例）和常规治疗组（44例），分别测定入院后第1、7、14天的血清NSE水平，并与对照组结果相互比较。结果：急性脑梗死患者血清NES水平明显高于对照组（P〈0．01），高压氧治疗组第7、14天血清NSE水平与常规治疗组比较的显著性差异变化（P〈0．01）。结论：NSE可以作为反映脑梗死患者脑细胞损伤程度的灵敏指标，早期高压氧治疗有助于减轻脑梗死病情。     

FGF、PDGF与动脉粥样硬化型脑梗死的相关性研究

目的观察脑梗死患者血清中成纤维细胞因子（FGF）和血小板源生长因子（PDGF）的变化,探讨其与动脉粥样硬化及脑梗死的关系。方法将50例动脉粥样硬化型脑梗死患者设为观察组,50例非动脉粥样硬化型相关疾病患者设为对照组。分别对比二者发病第1天和第7天血清中FGF与PDGF的含量。结果观察组患者血清中FGF及PDGF的含量明显高于对照组（P〈0．05）。FGF及PDGF在观察组第7天较第1天明显增高（P〈0．05）．而在对照组第7天较第1天无明显变化（P〉0．05）。结论FGF、PDGF与动脉粥样硬化型脑梗死关系密切,对动脉粥样硬化的形成及脑梗死的进一步发展起促进作用。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.