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异黄酮并木脂素类化合物是近20年来发现的异黄酮与木脂素发生骈和而形成的一类化合物,目前发现的异黄酮并木脂素类化合物,其结构类型仅有2种,在植物界的分布也仅存于豆科植物中,因此,其生物活性也鲜见报道。就此类化合物的结构类型、生物活性及其结构研究法的研究进展进行了综述。 相似文献
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木脂素是一类基本结构由苯丙素组成的多聚体,具有广泛的生物活性,其抗癌活性已引起国内外学者的广泛关注。对近年来从植物中获得的新的木脂素类化合物,从化学结构分类方面进行了综述,并简要介绍了部分化合物的生物活性。 相似文献
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香豆素并木脂素类化合物为近年来发现的香豆素与木脂素发生骈和而形成的一类化合物,其结构类型多样,在植物界分布广泛,且具有抗肿瘤、保肝、抑菌和抗氧化等活性。就近年来对此类化合物的植物分布、结构类型、生物活性及其结构研究方法的研究进展进行了综述。 相似文献
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香豆素并木脂素类化合物为近年来发现的香豆素与木脂素发生骈和而形成的一类化合物,其结构类型多样,在植物界分布广泛,且具有抗肿瘤、保肝、抑菌和抗氧化等活性.就近年来对此类化合物的植物分布、结构类型、生物活性及其结构研究方法的研究进展进行了综述. 相似文献
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FilleurF 《国外医药(植物药分册)》2002,17(6):254-254
长形肉豆蔻 Myristica argentea Warb.含有多种木脂素。作者从该植物汽油提取物中分离鉴定了4种木脂素,分别为 threo-aus-trobailignan-5(1,C_(20)H_(22)O_4)、erythro-aus-trobailignan-6(2,C_(20)H_(24)O_4),内消旋二氢愈创木酸(3,C_(20)H_(26)O_4)和樟皮碱B(4,C_(20)H_(24)O_5)。化合物1~3属于二苄基丁烷类木脂素,化合物4为二芳基四氢呋喃类化合物。化合物1和4系首次从该植物中分得。还分得去甲二氢愈创木酸(NDGA,5)。 相似文献
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大戟科植物珠子草Phyllanthus niruri L.为印度尼西亚的药用植物,广泛分布于中美洲、南美洲及亚洲的热带和亚热带地区,在传统医药中用于治疗黄疸、哮喘、肝炎和疟疾。已知珠子草的地上部分含有生物碱类、黄酮类、酚类、香豆素类、鞣质、萜类和木脂素等多种化学成分,其中对木脂素类研究最多,迄今已发现17种不同的木脂素,有些具有细胞毒等生物活性。作者为研究珠子草中木脂素类的产生和生物合成情况,制备了珠子草各部位(包括愈伤组织、地上部分、根、种子)的细胞悬浮培养液,并用GC—MS比较了它们木脂素类化合物的概况。结果显示,不同部位的细胞悬浮培养液中木脂素类化合物的数量和种类存在显著差异。另外,从细胞悬浮培养液中分离出2个木脂素类化合物荜澄茄素二甲醚(cubebin dimethyl ether,1)和urinatetralin(2),其中化合物2为首次从珠子草中分得,化合物1为新的木脂素。 相似文献
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植物中新的木脂素类化合物及其生物活性 总被引:2,自引:0,他引:2
木脂素是一类基本结构由苯丙素组成的多聚体,具有广泛的生物活性,其抗癌活性已引起国内外学者的广泛关注。对近年来从植物中获得的新的木脂素类化合物,从化学结构分类方面进行了综述,并简要介绍了部分化合物的生物活性。 相似文献
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南五味子属药用植物的化学成分及其生物活性 总被引:10,自引:0,他引:10
综述了自上世纪90年代初以来对五味子科南五味子属药用植物的化学成分及其生物活性的研究工作。我们从5种南五味子属药用植物的藤茎中共分离鉴定了80余种化合物,并主要探讨了这些化合物的抗脂质过氧化、钙拮抗和PAF拮抗等与补血活血作用相关的生物活性,同时也尝试抗HIV方面的研究工作,发现部分木脂素和三萜类化学成分具有显著的生物活性。 相似文献
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Genus Alpinia consists of over 250 species, which are widely distributed in south and southeast Asia. Many plants of genus Alpinia have been used for thousands of years to treat digestive system diseases and as anti-inflammatory drugs. Phytochemical research on this genus has led to the isolation of different kinds of diarylheptanoids, terpenes triterpenoids, phenylbutanoids, lignans, and flavonoids. Experimental evidences revealed that both the crude extracts and pure constituents isolated from the genus Alpinia exhibit a wide range of bioactivities such as anticancer, anti-oxidant, anti-bacterial, anti-viral, cardiovascular, and digestive system protective effects. Here, we summarize the phytochemistry and pharmacology investigation of the genus Alpinia, which can provide reference for further research and drug development. 相似文献
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Badalahu Tai Laxinamujila Bai Ruifeng Ji Muyao Yu NAla Luqi Huang Han Zheng 《中草药(英文版)》2022,14(3):392-402
Syringa oblata is a traditional Mongolian medicine mainly distributed in the Helan Mountains (the boundaries of Inner Mongolia and Ningxia, China) and the north of Yan Mountains (Aohan Qi, Inner Mongolia, China). It is clinically used to treat diseases caused by Heyi, such as heartache and heat pathogen in the heart. Phytochemical studies on S. oblata revealed the presence of iridoids, lignans, triterpenes, phenylpropanoids, phenylethanoids, and volatile components. Pharmacological investigations revealed a broad spectrum of bioactivities, such as antimicrobial, antioxidant, antiproliferative, and hepatoprotective effects. This article summarized the chemical components and pharmacological activities of S. oblata, providing a scientific rationale for its bioactive constituents, quality control, and utilization as an important medicine. 相似文献
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Choi YW Takamatsu S Khan SI Srinivas PV Ferreira D Zhao J Khan IA 《Journal of natural products》2006,69(3):356-359
Phytochemical investigation of the fruits of Schisandra chinensis led to the isolation of 13 lignans including schisandrene (13), a new lignan based on a dibenzocyclooctadiene backbone with an exocyclic double bond. Its structure and absolute configuration were established using NMR, MS, and CD data. Antioxidant activity of the lignans was evaluated using a DCFH-DA cellular-based assay. The structure-activity relationships of the dibenzocyclooctadiene lignans showed that the exocyclic methylene functionality was essential for antioxidant activity, with the benzoyloxy group probably enhancing such effects. 相似文献
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Shan‐Cheng Ren Chuan‐Liang Xu Khalid Rahman Lu‐Ping Qin Ying‐Hao Sun 《Phytotherapy research : PTR》2015,29(5):633-647
The article aims to review all the chemical constituents and pharmacological properties of Vitex negundo L. (Verbenaceae) (VN). VN is an important medicinal plant used as reputed herbal medicine with versatile pharmacological activities in China, India and Japan. A total of 104 referred articles about VN were compiled from major databases and academic publishers, such as MEDLINE, Pubmed, Scholar, Elsevier, Springer, Wiley and CNKI. As a result, a total of 120 compounds isolated from VN can be divided mainly into four classes: flavonoids, lignans, terpenoids and steroids. The crude extracts and purified compounds of VN exhibited promising bioactivities, including anti‐nociceptive, antiinflammatory, anti‐tumor, anti‐oxidant, insecticidal, antimicrobial, anti‐androgenic, anti‐osteoporotic, anti‐cataract, hepatoprotective and anti‐hyperglycemic activity. All the reported data lead us to conclude that VN has convincing medicinal potential. However, further researches are needed to explore its bioactive constituents, the structure–activity relationship and their molecular mechanisms of action. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
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Gao XM Pu JX Huang SX Yang LM Huang H Xiao WL Zheng YT Sun HD 《Journal of natural products》2008,71(4):558-563
Phytochemical investigation of Kadsura angustifolia led to the isolation and identification of 26 lignans and two triterpenoids, including 11 new lignans named kadangustins A-K ( 1- 11). The structures and stereochemistry of 1- 11 were elucidated by analysis of spectroscopic data. Except for 11 and 20, all the lignans were evaluated for their inhibitory activity against HIV-1. Binankadsurin A ( 19) showed anti-HIV activity with an EC 50 value of 3.86 microM. 相似文献