大柴胡汤治疗急性胰腺炎37例

目的研究分析大柴胡汤治疗急性胰腺炎的临床价值。方法选取2011年10月至2012年9月收治的74例急性胰腺炎患者的临床资料进行研究分析,并随机将其分为治疗组（37例）和对照组（37例）,对照组患者采用常规临床治疗措施进行治疗,治疗组患者在常规治疗基础上加以大柴胡汤进行治疗,对比两组患者治疗效果。结果治疗组患者临床治疗总有效率为94.59%,对照组患者临床治疗总有效率为72.97%。对比两组临床治疗效果,治疗组患者临床治疗总有效率显著优于对照组,差异有统计学意义（P〈0.05）。结论大柴胡汤在治疗急性胰腺炎临床上效果显著,可有效改善患者临床症状,提高患者生活质量,值得推广应用。     

临床药师参与2型糖尿病患者临床治疗体会

目的:探讨临床药师在2型糖尿病患者临床治疗中的指导作用。方法:参与2型糖尿病患者的药物治疗过程并加以分析。结果:临床药师参与临床治疗过程,可提高临床药物治疗水平,提高临床治愈率,减少不良反应的发生,并增加患者用药的依从性。结论:临床药师参与临床治疗可提高医疗质量。     

中西医结合治疗小儿病毒性心肌炎疗效观察

目的：探讨中西医结合治疗小儿病毒性心肌炎的临床效果。方法：回顾性分析我院78例病毒性心肌炎患儿的临床资料,根据患者的治疗方法差异分为治疗组和对照组,分别采用中西医结合及常规方法进行治疗,比较两组患儿治疗之后的临床疗效,并进行统计学分析,研究中西医结合治疗的临床疗效。结果：治疗完成之后治疗组患者的临床治疗效果与对照组具有显著统计学差异,（P<0.05）,患儿的体征消退较短,症状改善非常明显,临床疗效显著。结论：在临床小儿病毒性心肌炎患者的治疗当中,采用中西医结合的方法进行治疗可以有效提高患者治疗效果,临床上值得进行推广使用。     

头痛患者的临床诊治探讨

目的:探讨头痛患者有效的临床诊治方法,提高患者的临床疗效。方法:挑选2008年9月-2012年1月在我院进行头痛治疗的300例患者,按照就诊时间的先后顺序,分别采用中医治疗方案、西医治疗方案以及中西医结合治疗方案。对比观察3组患者的临床治疗疗效,寻找头痛的有效治疗方法。结果:采用中西医结合治疗组的患者的临床治疗有效率高达96%。而采用中医治疗组患者的临床治疗有效率为72%,采用西医治疗组患者的临床治疗有效率为75%。两组患者的临床疗效较中西医结合治疗组患者的均存在明显的统计学差异。结论:头痛的临床诊治困难,中西医结合临床能够显著提高患者的临床疗效,值得临床的广泛推广及应用。     

针灸与中药疗法治疗风湿病临床体会

目的：针灸与中药疗法治疗风湿病的临床体会.方法：选取风湿病患者42例,随机分为治疗组与对照组各21例,对照组采用内服中药方法进行治疗,治疗组在此基础上联合针灸进行治疗,比较两组患者的临床效果.结果：对照组患者治疗后的临床总有效率为61.90％,治疗组患者治疗后的临床总有效率为95.24％,治疗组的临床治疗效果明显高于对照组,差异具有统计学意义（P＜0.05）.结论：采取中药联合针灸疗法治疗风湿病具有较好的临床效果,可以提高患者的治愈率,值得临床推广应用.     

中药加针刺治疗失眠100例

目的 使用中医方法 改善失眠患者的睡眠状况,提高患者的生活质量.方法 对2010年2月至2011年12月在我院进行失眠治疗的患者,使用中医的治疗方法 对此100例患者辨证治疗.结果 此100例患者中,经过中医治疗方法 后,57例患者临床痊愈,24例患者的临床治疗显效,17例患者临床治疗有效,仅2例患者经过中医治疗后临床疗效未见明显好转.此100例患者的临床治疗总体有效率约为98%.结论 中医治疗失眠具有显著、确切的临床疗效,值得临床推广.     

手术治疗胃溃疡90例临床疗效观察

目的:探讨手术治疗和保守治疗胃溃疡的临床效果情况。方法:选取120例胃溃疡患者作为研究对象,根据治疗措施不同分为手术治疗组90例和保守治疗组30例。观察两组胃溃疡临床治疗效率情况。结果:手术治疗组胃溃疡临床治疗总有效率明显高于保守治疗组,差异有统计学意义(P0.05)。结论:根据不同临床分型给予胃溃疡患者相应的手术治疗,能有效提高胃溃疡临床治疗效果,降低术后复发,值得临床推广应用。     

中西药联合使用在老年性支气管哮喘治疗中的应用

目的：探讨中西药联合使用在老年性支气管哮喘治疗中的临床疗效。方法：选取2012年3月—2014年3月期间在我院住院治疗的老年性支气管哮喘患者60例,随机分为治疗组30例与对照组30例,对照组给予西医常规治疗,治疗组在其基础上加用中医辨证治疗,对两组患者的临床治疗效果进行对比分析。结果：对照组患者的临床治疗有效率为80.00%,治疗组患者的临床治疗有效率为96.67%,治疗组患者的临床疗效明显高于对照组,两组之间存在显著性差异,P〈0.05。结论：采取中西医结合治疗方法进行治疗的临床治疗效果较为理想,安全性较高,值得在临床治疗中应用。     

针刺结合半导体激光照射治疗Hunt面瘫32例

目的 观察针刺结合半导体激光照射治疗Hunt面瘫的临床疗效.方法 将63例Hunt面瘫患者随机分为2组,治疗组32例用针刺结合半导体激光照射治疗,对照组31例单纯用针刺治疗,比较2组临床症状积分和临床疗效.结果 2组治疗前后临床症状积分比较差异有统计学意义(P < 0.01),2组对Hunt面瘫均有治疗作用,治疗后优于治疗前.2组治疗后临床症状积分比较差异有统计学意义(P<0.01),治疗组对临床症状的改善情况优于对照组.2组总有效率比较差异有统计学意义(P<0.05),治疗组临床疗效优于对照组.结论 针刺结合半导体激光照射治疗Hunt面瘫和单纯针刺治疗均有良好疗效,针刺结合半导体激光照射治疗Hunt面瘫临床疗效优于单纯针刺治疗.     

中医内外综治慢性疲劳综合征临床研究

目的:探讨中医内外综治慢性疲劳综合征临床效果。方法:选取我院2010年1月-2012年12月收治慢性疲劳综合征患者140例,采用随机数字表法分为西医治疗组和中医综合治疗组,每组各70例;其中西医治疗组患者给予西医药物治疗,中医综合治疗组患者则给予归脾汤口服及穴位针刺治疗;比较两组患者临床改善总有效率及治疗前后临床症状积分等。结果:西医治疗组和中医综合治疗组患者临床改善总有效率分别为70.0%,94.3%;中医综合治疗组患者临床改善总有效率明显高于西医治疗组(P0.05);西医治疗组和中医综合治疗组患者治疗前临床症状积分组间比较无显著差异(P0.05);两组患者治疗后临床症状积分均明显低于治疗前,且中医综合治疗组患者降低程度明显高于西医治疗组(P0.05)。结论:中医内外综治慢性疲劳综合征临床效果确切,可有效改善临床症状,提高生活质量。     

Die Lateralität und Lateralitätsinstabilität in der Diagnostik und Therapie

The disturbance and instability of laterality are obstacles to diagnostics and therapy. Correction prior to starting therapy is required. They also predispose toward defined health problems and unspecific diseases. Numerous research activities provide evidence of the relevance of undisturbed laterality in diagnostics and therapy. Techniques of testing and therapeutic corrections will allow for optimized therapy success.     

Ethnopharmacologic study of chinese rhubarb

This paper deals with an interdisciplinary study covering historic, botanical, phytochemical, pharmacological and clinical aspects of rhubarb and related species, to lay stress on the correlation between plant phylogeny, chemical constituents and purgative activity.

It was found that the official rhubarbs were exclusively restricted in the Sect. Palmata e.g. Rheum palmatum R. palmatum var. tanguticum R. officinale; the following criteria may serve as their standard, viz., the presence of sennoside derivatives and rhein, the occurrence of the reduced form of rhein and aloe-emodin, the leaves with any kind of palmate incision. Comprehensive multivariate analyses showed that there is a very close relationship between the leaf incision, existence of sennosides or rhein and purgative activity.     

Effects of Radix Ginseng on microbial infections： a narrative review

OBJECTIVE： To summarized the antimicrobial-like effects of Radix Ginseng, which provide important information to the relevant researchers and clinicians, and will benefit the clinical treatment of infectious diseases. METHODS： PubMed and Google were used to search for and collect scientific publications related to Radix Ginseng and microbial infections. The authors read, classified, and discussed the associated scientific results or evidences, and summarized the corresponding results. RESULTS： In this review, recent studies on the beneficial effects of Radix Ginseng extracts on microbial and biofilm infections were reviewed. The impor- tance and significance of Radix Ginseng＇s beneficial effects are discussed. Evidence for the favorable ef- fects of Radix Ginseng extracts on viral, bacterial, fungal, and parasitic infections and the possible un- derlying mechanisms are summarized. CONCLUSION-＂ Radix Ginseng might be a promising supplemental remedy for the prevention and treat- ment of infectious diseases.     

薯蓣皂苷水解微生物的筛选

目的:筛选可水解薯蓣皂苷的微生物。方法:从盾叶薯蓣根茎表面、根际土壤、叶片及根茎内筛选可降解薯蓣皂苷得皂苷元的菌株,薯蓣皂苷元采用薄层层析和高效液相色谱法鉴定。结果:筛选得到水解薯蓣皂苷的微生物,经鉴定分别属于曲霉属和交链孢属,并对其中一株菌的产酶特性和发酵工艺进行了初步研究。结论:筛选菌株分泌的薯蓣皂苷水解酶,可水解薯蓣皂苷得到皂苷元。     

Analgesic effect of different moxibustion durations in rheumatoid arthritis rats

OBJECTIVE： To observe the influence of different moxibustion durations on hypothalamic pro-opi- omelanocortin（POMC） and prodynorphin（PDYN） mRNA expressions and plasma β-endorphin（β-EP） content in rheumatoid arthritis（RA） rats, to under- stand the mechanism of moxibustion analgesia and its dose-effect relationship. METHODS： Twelve male Wistar rats were randomly selected from 48 male Wistar rats as a normal con- trol group. The RA model was created by raising rats in a windy（blowing with electric fan）, cold（6 ℃ ±2 ℃）, and wet（80%-90% humidity） environ- ment for 20 days, 12 h each day. This was followed byinjectionofFreund＇scompleteadjuvant（0.15 mL） into the ankle. Then, rats were randomly divided in- to a model group, moxibustion group Ⅰ, and moxi- bustion group Ⅱ, with 12 rats in each group. In moxibustion groups Ⅰ and Ⅱ, moxibustion was given at Shenshu（BL 23） and Zusanli（ST 36） for 20 and 40 min, respectively, once daily for 15 days. Hy- pothalamic POMC and PDYN mRNA expression lev- els and plasma β-EP content were determined.RESULTS： Compared with the normal group, the pressure pain threshold decreased, while the hypo- thalamic POMC and PDYN mRNA expression levels and plasma β-EP content increased in the moxibus- tion groups（P0.01）. Compared with the model group, the pressure pain threshold, hypothalamic POMC and PDYN mRNA expression levels and plas- ma β-EP content in the moxibustion groups in- creased significantly（P0.01）. Compared the moxi- bustion groupⅠ, the pain threshold, hypothalamic POMC and PDYN mRNA expression levels and plas- ma β-EP content in moxibustion groupⅡsignifi- cantly increased（P0.01）. CONCLUSION： Moxibustion has an analgesic effect and increases hypothalamic POMC and PDYN mRNA expression levels and plasma β-EP content inRArats.Theanalgesiceffectinmoxibustiongroup ⅡisbetterthanthatinmoxibustiongroupⅠ.     

Wirksamkeit der Akupunktur bei der Therapie von idiopathischen Schmeckstörungen: Eine randomisierte Placebo-kontrollierte Studie

Background

At present, the state-of-the-art medication in treating idiopathic taste disorder (gustatory dysfunction) is zinc. If zinc medication was unsuccessful, not tolerated or if it is contraindicated the persons affected can hardly be helped.

Objectives

In a randomized placebo-controlled clinical trial an attempt was made to determine the efficacy of acupuncture.

Methods

The treatment group was treated with acupuncture needles, the placebo group with an inactive acupuncture-laser. Endpoints of the study were changes in the taste test, the quality of life and the severity of symptoms of depression (BDI) as well as mood changes (ZMS). Satisfaction with the success of the respective therapy was also evaluated. Data were collected before and after therapy and again for the treatment group 10 weeks after completion of the treatment period.

Findings

Treatment with real acupuncture showed a significant improvement in gustatory function as well as a significant improvement in psychological symptoms. Greater satisfaction with the treatment results was evident in the treatment group. The treatment results of acupuncture remained stable over a period of ten weeks after completion of the treatment.

Conclusion

Acupuncture was effective in the therapy of idiopathic taste disorders and therefore it is an effective alternative when zinc medication is not tolerated or unsuccessful. But it is also suitable as a therapy of first choice. Acupuncture can be considered as an extension of the therapeutic spectrum in the difficult treatment of taste disorders.     

HPLC同时测定新健胃包芯片中5种蒽醌类成分的含量

目的:建立HPLC法测定新健胃包芯片中5种蒽醌类成分的含量。方法:色谱柱:Diamonsil C8柱,流动相:甲醇(A)-0.3%磷酸(B)梯度洗脱,柱温:25℃,流速:1.0mL·min-1,检测波长:430nm。结果:芦荟大黄素、大黄酸、大黄素、大黄酚、大黄素甲醚平均回收率(n=9)分别为99.5%,97.7%,105.4%,100.1%,106.1%,RSD值分别为1.15%,1.76%,1.79%,1.74%,1.93%;芦荟大黄素、大黄酸、大黄素、大黄酚、大黄素甲醚分别在进样量为0.041～0.205、0.041～0.202、0.049～0.245、0.097～0.484、0.042～0.212μg与峰面积呈良好线性关系。结论:该方法简便、灵敏、结果准确可靠,适用于该制剂中蒽醌类成分的质量控制。     

金世元学术思想传承及临床用药经验（一）

金世元教授从事中药工作70余年,对中药鉴定、中药炮制、中成药合理使用以及中药调剂等多方面领域均有建树,形成了独到的“医药兼通”的学术思想特色。针对当今临床用药情况,将其用药实践经验进行初步总结。如橘红和陈皮的药用品种已与传统使用不符,药材品质明显不及以前;再如当归、甘草、黄芩和乌药的药用部位与传统发生变化,致使药效有所偏差;传统鲜药钱菖蒲已经失传,应延续使用等现代临床用药中涉及到的关于药用历史、品种变迁、药用部位变化、炮制工艺改变等多方面进行阶段性总结,以供中医药管理部门、生产和临床应用参考。     

Methodology of Canine/Feline YNSA and Tail Acupuncture

BackgroundYamamoto New Scalp Acupuncture (YNSA) is a well-known acupuncture system for human patients which was developed by Dr. Yamamoto.ObjectiveMy aim was to transpose the human YNSA map onto canines and felines.MethodI started researching a canine/feline YNSA map in 2002. I investigated approximately 3,000 canines and felines for YNSA and 2,500 for Tail Acupuncture. The ratio of canines and felines was 6 to 4. I researched and found all the equivalent points by palpating animal patients on the basis of an exact Neck Diagnosis.ResultsI nearly completed the map in 2006. The points in the occipital region are incomplete and my research is still in progress. In the process of researching canine/feline YNSA points, I accidentally found the other microsystems around the tail and named it “Tail Acupuncture”.ConclusionsYNSA and Tail Acupuncture are acupuncture systems utilizing microsystems and support each other in canines and felines. The merits of YNSA and Tail Acupuncture are 1) immediate effects, such as in cases of lameness, 2) simplicity in finding the exact points to treat and 3) the scalp and the tail can be utilized separately or together as treatment zones, according to the situation.     

肝达康对DMN致大鼠肝损伤血清ALT、AST、TBIL、TP及ALB的影响

目的:研究肝达康对二甲基亚硝胺(DMN)致大鼠肝损伤模型的保护作用。方法:雄性Wistar大鼠55只,随机分为正常对照组(n=10)、模型组(n=15)、肝达康预防组(n=15)及秋水仙碱组(n=15)。模型组、肝达康预防组和秋水仙碱组以10mg/kg DMN腹腔注射,每日1次,每周连续3天,共4周。以上3组在造模同时给予药物或生理盐水灌胃。于第4周末处死全部大鼠,留取血清。采用全自动生化分析仪检测ALT、AST、TBIL、TP、ALB。结果:与正常对照组比较,模型组大鼠血清ALT和AST活性显著增高,TBIL水平明显升高,ALB和TP含量降低。肝达康颗粒治疗后使ALT和AST活性降低,TBIL水平降低,TP和Alb含量升高。秋水仙碱组可降低ALT和AST活性,使ALB含量升高,但对TP含量和TBIL水平均无调节作用。结论:肝达康对实验性大鼠肝损伤模型具有明显改善肝功能的作用。