鼻内镜手术治疗真菌性鼻窦炎96例报告

目的探讨真菌性鼻窦炎的发病原因及鼻内镜手术治疗非侵袭性真菌性鼻窦炎的疗效。方法采用鼻内镜手术治疗非侵袭性鼻窦炎96例,分析其临床表现、鼻内镜检查和鼻窦CT扫描特征及手术疗效。结果 96例患者经鼻内镜检查及鼻窦CT扫描显示,鼻腔均有不同程度解剖异常和病变特征,术后病理学检查均发现真菌丝,随访6个月-2年,治愈85例（88.54%）,显效9例（9.38%）,无效2例（2.08%）。结论非侵袭性真菌性鼻窦炎与鼻腔解剖异常及病变有关系,鼻内镜检查和鼻窦CT是诊断真菌性鼻窦炎的重要方法,鼻内镜手术是治疗本病的重要手段。     

鼻内窥镜手术结合术后鼻腔冲洗治疗非侵袭性真菌性鼻窦炎的临床分析

目的探讨功能性内镜鼻窦手术结合术后鼻腔冲洗治疗非侵袭性真菌性鼻窦炎的临床疗效。方法对32例非侵袭性真菌性鼻窦炎采用功能性内镜鼻窦手术,术后结合鼻腔冲洗3个月,术后随访1年,分析其疗效。结果 31例患者术后3～6个月术腔上皮化,1例半年复发,经再次手术治愈,随访1年后复查鼻内镜及鼻窦CT未见复发。结论功能性内镜鼻窦手术是治疗非侵袭性真菌性鼻窦炎微创、有效的手术方式,术后结合鼻腔冲洗促进愈合,减少复发,值得临床推广。     

鼻内镜手术治疗非侵袭性真菌性鼻-鼻窦炎

目的探讨非侵袭性真菌性鼻-鼻窦炎的临床特征,鼻内镜手术方法及疗效.方法回顾分析102例非侵袭性真菌性鼻-鼻窦炎的临床资料.结果所有患者均行鼻内镜手术治疗,随访6个月—4年,治愈77例,好转20例,复发5例.结论鼻腔解剖异常是非侵袭性真菌性鼻-鼻窦炎的主要致病因素.鼻内镜手术是治疗非侵袭性真菌性鼻-鼻窦炎的有效手段,术后复发与手术的彻底性、术后鼻腔鼻窦处理有关.     

鼻内镜手术治疗非侵袭性真菌性鼻-鼻窦炎的临床分析

目的:分析鼻内镜手术治疗非侵袭性真菌性鼻-鼻窦炎的临床疗效。方法:对采用鼻内镜手术治疗的97例非侵袭性真菌性鼻-鼻窦炎患者的临床资料进行回顾性分析,对临床疗效进行分析总结。结果:97患者术后均随访6~12个月,90例治愈,5例好转,总有效率为97.9%,2例手术患者术后未定期鼻腔局部用药和鼻内镜下鼻腔清理,临床症状复发,行第二次手术。术后病理报告为曲霉菌感染。结论:鼻腔局部的解剖异常和病变是引起非侵袭性真菌性鼻-鼻窦炎的主要原因,鼻内镜检查和鼻窦CT或MRI检查是明确诊断的重要方法,鼻内镜手术是治疗非侵袭性真菌性鼻-鼻窦炎最为有效的方法,术后综合治疗是防止疾病复发确保疗效的重要措施。     

鼻内镜手术治疗非侵袭型真菌性鼻窦炎分析

目的探讨鼻内窥镜术在治疗非侵袭型真菌性鼻窦炎的临床疗效,及其临床表现、CT的表现及诊断价值;以及真菌性鼻窦炎与鼻腔、鼻窦解剖异常和局部病变的关系。方法采用鼻内窥镜术治疗非侵袭型真菌性鼻窦炎35例。结果鼻内窥镜术治愈为85.7%。结论功能性鼻内窥镜术是治疗非侵袭型真菌性鼻窦炎的有效微创手术,CT是诊断真菌性鼻窦炎重要的有价值的检查方法,矫正鼻腔的解剖异常及消除局部病变对术后的恢复有重要的作用。     

CT诊断真菌性鼻窦炎100例分析

目的回顾性总结真菌性鼻窦炎CT影像表现,并结合临床,探讨CT检查对诊断真菌性鼻窦炎的临床价值。方法收集100例确诊为真菌性鼻窦炎的病人资料并结合临床检查结果,与CT检查进行分析比较。鼻窦CT扫描采用骨窗和软组织窗扫描。结果 100例患者均为单侧鼻窦发病,其中真菌球型68例,慢性侵袭性真菌性鼻窦炎4例,变应性真菌性鼻窦炎28例。CT扫描影像特点为鼻窦腔散在较均匀毛玻璃特征或极不规则的线状,有星状分布的钙化点;伴不同程度骨质吸收或结构不清;窦壁骨质侵蚀15例。病变延伸到邻近结构3例,其中1例累及眼眶。有2例侧颅底骨质吸收。鼻腔或鼻窦内分布黏蛋白与CT显示毛玻璃样高密度影一致。结论真菌性鼻窦炎的鼻窦CT扫描显示与其他鼻窦炎不同。CT检查有助于准确诊断真菌性鼻窦炎。     

鼻窦内窥镜手术治疗真菌性鼻窦炎36例临床分析

目的探讨鼻窦内窥镜治疗真菌性鼻-鼻窦炎的临床疗效。方法回顾性分析经病理确诊为真菌性鼻窦炎（FS）的36例患者的临床表现、鼻窦CT病变特征,以及鼻窦内窥镜下鼻窦开放的治疗效果。结果鼻窦CT扫描显示36例患者窦腔内均有病灶,且术后全部病例的病变组织中均能找到霉菌菌丝或孢子,临床分型均属非侵袭性FS。术后随访0.5～2a,治愈34例（94.4%）,显效2例（5.6%）。结论鼻窦内窥镜手术是治疗真菌性鼻-鼻窦炎的首选治疗方式。     

鼻内镜手术治疗非侵袭型真菌性鼻窦炎分析

目的探讨鼻内窥镜术在治疗非侵袭型真菌性鼻窦炎的临床疗效，及其临床表现、CT的表现及诊断价值；以及真菌性鼻窦炎与鼻腔、鼻窦解剖异常和局部病变的关系。方法采用鼻内窥镜术治疗非侵袭型真菌性鼻窦炎35例。结果鼻内窥镜术治愈为85．7％。结论功能性鼻内窥镜术是治疗非侵袭型真菌性鼻窦炎的有效微创手术，CT是诊断真菌性鼻窦炎重要的有价值的检查方法，矫正鼻腔的解剖异常及消除局部病变对术后的恢复有重要的作用。     

鼻内镜手术治疗非侵袭性真菌性鼻—鼻窦炎临床分析

目的 探讨非侵袭性真菌性鼻—鼻窦炎发病原因及鼻内镜手术治疗非侵袭性真菌性鼻窦炎手术方式与术后疗效.方法 对56例非侵袭性真菌性鼻—鼻窦炎患者行鼻内窥镜手术.结果 术后随访6个月～2a.治愈55例(98.2％),显效1例(1.8％).结论 鼻腔、鼻窦真菌感染主要因素可能是鼻腔鼻窦的解剖结构存在异常和病变,阻碍了鼻腔鼻窦的通气引流.鼻内窥镜手术是治疗非侵袭性真菌性鼻—鼻窦炎的首选治疗方式,术中正确处理钩突、中鼻甲、鼻中隔,术前、术后综合性治疗,定期随访有利于提高疗效,减少并发症及复发率.     

鼻内窥镜手术结合术后鼻腔冲洗治疗非侵袭性真菌性鼻窦炎的临床研究

目的研究非侵袭性真菌性鼻窦炎鼻腔冲洗治疗在鼻窦手术结合术内镜治疗后的临床应用及作用。方法对44例确诊为非侵袭性真菌性鼻窦炎患者采用功能性鼻内窥镜手术。结果 42例患者术后2~4个月手术鼻腔上皮化,2例半年复发,经再次手术治愈。结论鼻内窦镜手术在治疗非侵袭性真菌性鼻窦炎中有较好的临床应用效果,术后结合鼻腔冲洗可以改善局部感染灶血运及炎症反应,促进愈合。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.