优质护理对老年慢性阻塞性肺疾病患者肺功能和生活质量的影响

目的：探讨优质护理对老年慢性阻塞性肺疾病患者肺功能和生活质量的影响。方法选择2013年3月—2015年3月我院收治的160例老年慢性阻塞性肺疾病患者,随机分成对照组和观察组,对照组给予常规护理,观察组给予优质护理,对2组患者肺功能、生活质量改善情况进行比较。结果观察组肺功能、生活质量改善情况明显优于对照组,差异有统计学意义（P<0.05）。结论优质护理能够改善老年慢性阻塞性肺疾病患者的肺功能及生活质量。     

护理干预对老年慢性阻塞性肺疾病患者生存质量的影响

目的:观察护理干预对老年慢性阻塞性肺疾病患者生存质量的影响。方法:将120例慢性阻塞性肺疾病患者分对照组与干预组,每组60例,对照组进行常规护理,而干预组除了常规护理外还对其进行护理干预。经过一段时间,对比干预前后患者生存质量和肺功能的情况。结果:干预组患者进行护理干预后生存质量明显的改善,而肺功能变化不明显。结论:对慢性阻塞性肺疾病患者干预组进行护理干预能够提高患者的生活质量,减少患者的病痛。     

护理干预在慢性阻塞性肺疾病患者中的应用研究

目的 探讨护理干预在慢性阻塞性肺疾病患者中的护理效果,改善患者的肺功能,提高患者的生存质量.方法 随机将80例慢性阻塞性肺疾病患者分为观察组和对照组各40例,观察组实施为期6个月的护理干预,对照组仅在就诊时进行宣教,比较2组患者的肺功能和生活质量.结果 观察组护理效果明显好于对照组,如肺功能改善情况和生活质量均高于对照...     

康复护理在老年慢性阻塞性肺疾病患者中的应用效果

目的探讨康复护理在老年慢性阻塞性肺疾病患者中的应用效果。方法选取平顶山市第一人民医院2017年4月至2018年6月90例老年慢性阻塞性肺疾病患者,按随机数表法分为对照组和观察组,各45例。对照组接受常规护理,观察组接受康复护理。采取满意度调查问卷调查患者满意程度,分别于护理前后采用GQOLI-74评价量表评估患者生活质量水平。结果对照组满意度为80.0%(36/45);观察组满意度为100.0%(45/45),观察组满意度高于对照组(P<0.05)。两组患者护理后生活质量评分均较护理前提高,且观察组高于对照组,差异有统计学意义(均P<0.05)。结论对老年慢性阻塞性肺疾病患者应用优质护理可以提高患者的生活质量,改善肺功能,患者满意度高。     

呼吸训练对慢性阻塞性肺疾病患者肺功能的影响及护理体会

目的分析呼吸训练对慢性阻塞性肺疾病患者肺功能的影响及护理方法和效果。方法选取2018年1月至2019年2月我院治疗的56例慢性阻塞性肺疾病患者,随机将患者分为观察组和对照组,每组均28例,其中,观察组患者应用呼吸训练并加强护理干预,对照组采用常规护理,对两组患者的血氧饱和度、动脉氧分压、二氧化碳分压等肺功能指标、生活质量评分、护理满意度进行对比分析。结果观察组患者血氧饱和度、动脉氧分压、二氧化碳分压等肺功能指标均明显优于对照组,差异具有统计学意义(P0.05);观察组患者生活质量评分、护理满意度评分均明显高于对照组患者(P0.05)。结论开展呼吸训练,不仅对改善慢性阻塞性肺疾病患者肺功能具有非常积极的影响,还能改善患者的生活质量和满意度,值得临床推广应用。     

呼吸功能锻炼联合饮食护理对慢性阻塞性肺疾病患者生活质量的干预效果

目的:探讨呼吸功能锻炼联合饮食护理对慢性阻塞性肺疾病患者生活质量的影响。方法:选取2017年2月—2019年2月于我院就诊的慢性阻塞性肺疾病患者70例,按随机数字表法分为两组,各35例。对照组给予常规护理,观察组给予呼吸功能锻炼联合饮食护理干预。对比两组生活质量及肺功能。结果:观察组物质生活、社会功能、心理功能、躯体功能评分均高于对照组,差异有统计学意义(P<0.05)。观察组肺活量、肺泡通气量均高于对照组,差异有统计学意义(P<0.05)。结论:呼吸功能锻炼联合饮食护理可有效提高慢性阻塞性肺疾病患者生活质量,改善肺功能,值得应用。     

前瞻性护理干预在老年慢性阻塞性肺疾病患者中的护理效果及对肺功能的影响研究

目的:探讨前瞻性护理干预在老年慢性阻塞性肺疾病患者中的护理效果及对肺功能的影响。方法:选取2017年6月-2018年6月本院收治的老年慢性阻塞性肺疾病患者72例。按照随机数字表法将其分为对照组和观察组,各36例。对照组给予常规护理,观察组采用前瞻性护理干预,护理后1个月对患者进行评估,比较两组肺功能水平、应对方式评分及护理满意度。结果:护理后1个月,观察组FEV_1、FVC水平均高于对照组(P0.05),但两组FEV_1/FVC水平比较,差异无统计学意义(P0.05);观察组面对、乐观、情感化、保守、听天由命、自我依赖、寻求支持、逃避评分均低于对照组(P0.05);观察组满意度高于对照组(P0.05)。结论:前瞻性护理干预用于老年慢性阻塞性肺疾病患者中有助于改善患者肺功能水平,提高患者的应对方式及护理满意度,值得推广应用。     

综合性护理在接种流感疫苗治疗稳定期慢性阻塞性肺疾病中的应用

目的:探讨综合性护理在接种流感疫苗治疗稳定期慢性阻塞性肺疾病中的应用效果。方法:选取2014年12月-2016年1月龙华新区人民医院收治的50例稳定期慢性阻塞性肺疾病患者,按随机数字表法分为观察组和对照组,各25例。对照组给予常规护理,而观察组在此基础之上加用综合护理干预。比较两组COPD急性发作次数、肺功能改善情况以及生活质量评分。结果:观察组急性发作率显著低于对照组,差异有统计学意义(P0.05)。干预后观察组FVC、FEV1、FEV1/FVC及6MD等各项肺功能指标均显著高于对照组,差异均有统计学意义(P0.05)。干预后观察组生活质量总分显著高于对照组,差异有统计学意义(P0.05)。结论:综合性护理干预在老年稳定期慢性阻塞性肺疾病患者中临床效果良好,对于减少COPD急性发作次数、提高患者肺功能及生活质量作用显著,值得临床应用推广。     

优质护理干预在老年慢性阻塞性肺疾病患者中的应用体会

目的：探讨优质护理干预在老年慢性阻塞性肺疾病患者中的应用效果。方法选取我院2013年1月—2014年8月收治的50例老年慢性阻塞性肺疾病患者进行护理干预,分析护理效果。结果通过有效的护理干预,50例老年慢性阻塞性肺疾病患者中48例的肺功能改善,其有效率为96.0%。结论选择有效的护理措施,有利于提高老年慢性阻塞性肺疾病患者的治愈率,改善肺功能,提升患者生活质量,值得临床推广应用。     

综合护理干预对慢性阻塞性肺疾病患者生活质量及护理满意度的影响

目的观察分析综合护理干预对慢性阻塞性肺疾病(COPD)患者生活质量及护理满意度的影响。方法选取2015年5月至2016年5月新乡市第二人民医院收治的COPD患者100例,按照随机数表法分为观察组和对照组,各50例。两组治疗方案相同,对照组接受常规护理干预,观察组在常规护理的基础上接受综合护理干预,比较两组患者生活质量评分和护理满意度。结果干预前,两组生活质量评分比较,差异无统计学意义(P>0.05);干预后,观察组生活质量评分高于对照组,护理满意度高于对照组(98.0%比80.0%),差异均有统计学意义(P<0.05)。结论综合护理干预应用于慢性阻塞性肺疾病患者,可改善患者生活质量,提高护理满意度,值得推广。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.