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泽泻在心血管疾病治疗中的应用
引用本文:陈兴娟,尹萌萌,魏建梁,国兴宜,杨传华.泽泻在心血管疾病治疗中的应用[J].长春中医药大学学报,2014(4):620-622.
作者姓名:陈兴娟  尹萌萌  魏建梁  国兴宜  杨传华
作者单位:山东中医药大学;山东中医药大学附属医院高血压国家临床研究基地心内科;
基金项目:国家中医管理局中医药重点学科建设项目资助(2009);山东省“泰山学者”建设工程专项经费资助
摘    要:泽泻具有利水消肿、渗湿、泄热的功效。现代药理学研究证实,泽泻的多种有效成分如泽泻醇A、B及泽泻倍半萜类等具有降血压、降血脂、抗动脉粥样硬化、抗心肌缺血等药理作用。临床用于治疗高血压、动脉粥样硬化、高脂血症、冠心病、心肌缺血等多种心血管疾病,其治疗有效机制可能与降低外周阻力,改善微循环,抑制血小板聚集及抗动脉硬化等有关。

关 键 词:泽泻  高血压  动脉粥样硬化  高脂血症  冠心病

Application of Alisma in the treatment of cardiovascular diseases
Institution:CHEN Xingjuan, YIN Mengmeng, WEI Jianliang, GUO Xingyi, YANG Chuanhua ( 1. Shandong University of TCM, Jinan 250355, China; 2. Postgraduate, Shandong University of TCM, Jinan 250355, China; 3. Department of Cardiology, National Clinical Research Base of Hypertension, The Affiliated Hospital to Shandong University of TCM, Jinan 250011, China)
Abstract:Alisma has the function of inducing diuresis to alleviate edema, excreting dampness and discharging heat. Modem pharmacological studies proved that Alisma contains variety of active ingredients such as Alisol A, B and Alisma sesquiter- pene which have the effect of lowering blood pressure, reducing blood fat, anti-atherosclerosis, improving myocardial ischemia and other effects. It's effective in treating a variety of cardiovascular diseases such as hypertension, atherosclerosis, hyper- lipemia, coronary disease and ischemia myocardial. Its main effective mechanism maybe related with reducing peripheral re- sistance, improving microcirculation, inhibiting platelet aggregation and anti-atherosclerosis.
Keywords:Alisma  hypertension  athemsclemsis  hyperlipidemia  coronary heart disease
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