| 慢性心肌梗塞大鼠实验模型 |
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| 引用本文： | 刘元生,陈运贞.慢性心肌梗塞大鼠实验模型[J].重庆医科大学学报,2002,27(2):153-155. |
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| 作者姓名： | 刘元生 陈运贞 |
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| 作者单位： | 重庆医科大学临床学院心内科,重庆,400016 |
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| 摘 要： | 目的:建立慢性心肌梗塞大鼠实验模型。方法:大鼠用氯胺酮、戊巴比妥钠、阿托品和利多卡因复合麻醉,Wistar气管切开插管,经左胸第、肋间钝性分离开胸,结扎左冠状动脉前降支。 34结果:本法术后内大鼠死亡率仅为;存72h6.67%活周以上大鼠可达。378.1%结论:本技术操作简单、创伤轻、成功率高、结果可靠。
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| 关 键 词： | 心肌梗塞 大鼠 动物模型 |
| 文章编号： | 0253-3626(2002)02-0153-03 |
| 修稿时间： | 2001年12月1日 |
Experiment model of chronic myocardial infarction in rats |
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| LIU Yuansheng,et al.Experiment model of chronic myocardial infarction in rats[J].Journal of Chongqing Medical University,2002,27(2):153-155. |
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| Authors: | LIU Yuansheng |
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| Abstract: | Objective: To make animal model of chronic myocardial infarction in rats. Methods: Wistar rats were anaesthetized with ketamine, sodium phenobarbital, atropine and lidocaine. Tracheotomy intubation and left anterior thoracotomy through 3,4 intercostal region were performed. Left anterior`descending coronary artery was ligated. Results: Rat mortality was 6.67% in 72 hours after operation. The survival rate was 78.1% beyond 3 weeks. Conclusion: This showed that the operation procedure was easy to perform with slight damage and high survival rate. |
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| Keywords: | Myocardial infarction Rats Animal model |
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