翼状胬肉切除联合自体角膜缘干细胞移植术临床疗效观察

目的观察翼状胬肉切除联合自体角膜缘干细胞移植术治疗翼状胬肉的临床疗效。方法选择2013年2月-2014年2月眼科收治的翼状胬肉患者82例（86眼）,随机分为观察组43例（45眼）和对照组39例（41眼）。观察组行翼状胬肉切除联合自体角膜缘干细胞移植术,对照组行单纯翼状胬肉切除术。结果观察组患者角膜上皮化愈合时间短于对照组,术后眼内异物感、畏光、流泪等不适症状持续时间短于对照组,差异有统计学意义（P〈0.05）。观察组患者复发率低于对照组,差异有统计学意义（P〈0.05）。结论翼状胬肉切除联合自体角膜缘干细胞移植术取材容易,简单易行,可明显降低翼状胬肉术后的复发率,是一种治疗翼状胬肉行之有效的好方法。在翼状胬肉切除治疗中有效促进了眼表结构和功能的修复,对降低翼状胬肉复发率有重要意义。

Observation of the clinical effects of pterygium excision combined with autologous limbal stem cell transplantation

Objective To study the clinical effects of pterygium excision combined with autologous limbal stem cell transplantation. Method 82 pterygium patients were divided into experiment group and control group. 43 cases belonging to experiment group（45 eyes） were treated by pterygium excision combined with autologous limbal stem cell transplantation, and 39 cases belonging to control group（41 eyes） were treated by only pterygium excision. Results the corneal epithelium healing time of experiment group was notably shorter than those of control group（P〈0.05）. Meanwhile, the recurrence rate of experiment group was also significantly lower than that of control group（P〈0.05）. Conclusion Pterygium excision combined with autologous limbal stem cell transplantation is a good way to treat the pterygium for readily available of operation material and easy to operate. What is more, it reduced the recurrence rate after the pterygium excision due to effectively repairing the structure and function of ocular surface.