首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   1142篇
  免费   49篇
  国内免费   28篇
耳鼻咽喉   35篇
儿科学   4篇
妇产科学   67篇
基础医学   138篇
口腔科学   73篇
临床医学   99篇
内科学   42篇
皮肤病学   2篇
神经病学   10篇
特种医学   59篇
外科学   474篇
综合类   110篇
预防医学   21篇
眼科学   16篇
药学   22篇
中国医学   10篇
肿瘤学   37篇
  2024年   1篇
  2023年   15篇
  2022年   27篇
  2021年   36篇
  2020年   39篇
  2019年   48篇
  2018年   62篇
  2017年   34篇
  2016年   49篇
  2015年   65篇
  2014年   77篇
  2013年   65篇
  2012年   52篇
  2011年   61篇
  2010年   61篇
  2009年   65篇
  2008年   47篇
  2007年   43篇
  2006年   55篇
  2005年   47篇
  2004年   42篇
  2003年   25篇
  2002年   31篇
  2001年   19篇
  2000年   27篇
  1999年   26篇
  1998年   17篇
  1997年   19篇
  1996年   5篇
  1995年   6篇
  1994年   4篇
  1993年   2篇
  1992年   3篇
  1991年   3篇
  1990年   3篇
  1988年   4篇
  1987年   5篇
  1985年   7篇
  1984年   2篇
  1983年   3篇
  1982年   2篇
  1981年   2篇
  1980年   1篇
  1979年   3篇
  1978年   1篇
  1977年   5篇
  1976年   1篇
  1973年   2篇
排序方式: 共有1219条查询结果,搜索用时 15 毫秒
1.
《Cirugía espa?ola》2022,100(7):437-439
Complete liver mobilization for major resections sometimes causes liver tilting due to the release of the suspensory elements of the liver. Rarely this may take to a liver abnormal position with acute obstruction to venous flow at the suprahepatic level (Budd-Chiari syndrome). To avoid this complication, techniques such as post-operative stent implantation have been described. The case of a patient who underwent a complete mobilization of the liver for resection of the inferiour venous cava and a right renal tumor, was reported. After that, an acute Budd-Chiari Syndrome was observed caused of the liver malposition, which was solved with the placement of two silicone prostheses in the liver cell.  相似文献   
2.
目的探讨髋臼螺钉在非骨水泥全髋置换术中对髋臼假体稳定性的影响。 方法回顾性分析2009年8月至2015年8月在深圳市龙岗区人民医院骨科行非骨水泥全髋置换术114例(117髋)病例资料,患者根据术中是否植入髋臼螺钉分成两组,其中A组无螺钉组59髋,B组螺钉固定组58髋。分别在术后3个月、12个月、24个月和末次随访时对病人进行随访,评估并比较影像学的改变及Harris评分。A组57髋B组56髋获得完整随访资料,平均随访(5.7±1.6)年。以Kaplan-Meier法分析两组假体生存率。 结果A组平均手术时间(t=2.213, P<0.05)、术中出血量均小于B组(t=2.342, P<0.05);随访末期,A、B组术后平均Harris评分为(95.0±2.1)分及(93.0±5.5)分(P>0.05);A、B组术后3个月、12个月、24个月分别有4髋(7.0%)、3髋(5.3%)、1髋(1.8%)和1髋(1.8%)、2髋(3.6%)及2髋(3.6%)出现髋臼周围透亮线;A组1髋术后4年出现骨溶解,B组2髋出现骨溶解。以影像学证明假体松动作为失败标准,计算两组假体平均随访(5.7±1.6)年生存率分别为97%和95%,两者差异无统计学意义(P >0.05)。 结论髋臼骨质条件良好时是否使用髋臼螺钉固定对臼杯的稳定性无明显影响,全髋关节置换术中植入髋臼螺钉不是必需的。  相似文献   
3.
4.
BackgroundRunning-specific prostheses (RSPs) are biomechanically designed to enable individuals with lower limb amputations to engage in high level sports.Research questionWhat is the influence of RSP use on the running biomechanics of individuals with lower limb amputations?MethodsAn article search was conducted in six databases since their inception to July 2021. Two independent reviewers assessed the title, abstract and full texts in the review process. The quality of the papers was appraised. The review included a total of 35 articles.ResultsMain findings indicate force production is a limitation of RSPs. Individuals with lower limb absence employ a variety of compensatory strategies such as adjusting their step frequency, contact length and joint kinetics to improve their running performance. Leg stiffness modulation and external factors relating to the RSP design and fitting play important roles in RSP biomechanics. For individuals with unilateral amputations, the increased loading of the intact limb could increase the risk of acute injury or chronic joint degradation.SignificanceTo improve their running performance, runners with lower limb amputations employ various compensatory strategies, such as altering the spatiotemporal and kinetic parameters. Factors relating to RSP height, stiffness, shape, and alignment also play an important role in terms of running biomechanics and should be considered in RSP design and fitting. Future studies should focus on the use of RSPs for recreation, in pediatric populations, with certain amputation levels, as well as the impact of training and running techniques.  相似文献   
5.
Although the rate of patients reporting satisfaction is generally high after joint replacement surgery, up to 23% after total hip replacement and 34% after total knee arthroplasty of treated subjects report discomfort or pain 1 year after surgery. Moreover, chronic or subacute inflammation is reported in some cases even a long time after surgery. Another open and debated issue in prosthetic surgery is implant survivorship, especially when related to good prosthesis bone ingrowth. Pulsed Electro Magnetic Fields(PEMFs) treatment, although initially recommended after total joint replacement to promote bone ingrowth and to reduce inflammation and pain, is not currently part of usual clinical practice. The purpose of this review was to analyze existing literature on PEMFs effects in joint replacement surgery and to report results of clinical studies and current indications. We selected all currently available prospective studies or RCT on the use of PEMFs in total joint replacement with the purpose of investigating effects of PEMFs on recovery, pain relief and patients' satisfaction following hip, knee or shoulder arthroplasty. All the studies analyzed reported no adverse effects, and good patient compliance to the treatment. The available literature shows that early control of joint inflammation process in the first days after surgery through the use of PEMFs should be considered an effective completion of the surgical procedure to improve the patient's functional recovery.  相似文献   
6.
BackgroundMany patients with erectile dysfunction (ED) after radical prostatectomy (RP) improve with conservative therapy but some do not; penile prosthesis implantation rates have been sparsely reported, and have used nonrepresentative data sets.AimTo characterize rates and timing of penile prosthesis implantation after RP and to identify predictors of implantation using a more representative data set.MethodsThe Healthcare Cost and Utilization Project State Inpatient and State Ambulatory Surgery databases for Florida from 2006 to 2015 were used. Patients undergoing RP (2006–2012) were tracked longitudinally for penile prosthesis implantation. Patient and clinical data were analyzed using multivariable logistic regression.OutcomesThe primary outcome was risk-adjusted predictors of prosthesis implantation, and the secondary outcome was predictors of the highest quartile of time between RP and penile prosthesis.ResultsOf 29,288 men who had RP, 1,449 (4.9%) patients underwent subsequent prosthesis. The mean time from RP to prosthesis was 2.6 years (median: 2.1; interquartile range [IQR]: 1.2–3.5). Adjusted predictors of prosthesis implantation included open RP (odds ratio [OR]: 1.5, P < .01), African American race (OR: 1.7, P < .01) or Hispanic ethnicity (OR: 3.2, P < .01), and Medicare (OR: 1.4, P < .01) insurance. Oler patients (age >70 years; OR: 0.7, P < .01) and those from the highest income quartile relative to the lowest (OR: 0.8, P < .05) were less likely to be implanted. Adjusted predictors of longer RP-to-implantation time (highest quartile: median: 4.7 years; IQR: 3.9–6.0 years) included open RP (OR: 1.78, P < .01), laparoscopic RP (OR: 4.67, P < .01), Medicaid (OR: 3.03, P < .05), private insurance (OR: 2.57, P < .01), and being in the highest income quartile (OR: 2.52, P < .01).Clinical ImplicationsThese findings suggest ED treatment healthcare disparities meriting further investigation; upfront counseling on all ED treatment modalities and close monitoring for conservative treatment failure may reduce lost quality of life years.Strengths & LimitationsThis study is limited by its use of administrative data, which relies on accurate coding and lacks data on ED questionnaires/prior treatments, patient-level cost, and oncologic outcomes. Quartile-based analysis of income and time between RP and prosthesis limits the conclusions that can be drawn.ConclusionLess than 5% of post-RP patients undergo penile prosthesis implantation, with open RP, Medicare, African American race, and Hispanic ethnicity predicting post-RP implantation; living in the wealthiest residential areas predicts lower likelihood of implantation compared to the least wealthy areas. Patients with the longest time between RP and prosthesis are more likely to live in the wealthiest areas or have undergone open/laparoscopic RP relative to robotic RP.Bajic P, Patel PM, Nelson MH, et al. Penile Prosthesis Implantation and Timing Disparities After Radical Prostatectomy: Results From a Statewide Claims Database. J Sex Med 2020;17:1175–1181.  相似文献   
7.

Introduction

In this retrospective study we have analyzed a consecutive series of patients affected by isolated radial head Mason III fractures and treated with bone resection or prosthesis.

Patients and methods

This study includes 24 patients affected by fractures mentioned above and treated between July 2009 and November 2015.15 patients (average age 48 y.o.) have been treated with prosthesis. The remaining 9 (average age 573) have been treated with a capitellectomy instead.From a clinical point of view, we have evaluated the patients according to main performance indicators such as range of motion, pain, instability and Mayo Elbow Performance Score as parameters.

Results

We have found similar results in both group, with an average MEPS value of 95 in the prosthesis group and 966 in the radial head resection group.The range of motion was similar too: between 1,3° and 1203° in the first group and between 4,4° and 120° in the second one. No significant complication has detected in any patient.

Discussion

According to most recent literature, it is not precisely defined how to treat isolated Mason III fractures, contrary to what is defined in more complex pattern, in which prosthesis are now evaluated as the best indication.Due to radial head limited contribution to elbow stability, in absence of other bony or ligamentous lesions both capitellectomy and prosthesis can be good treatment in this kind of fracture.

Conclusion

According to our experience and to the most recent literature, we recommend prosthesis in patient younger than 50 y.o., high demanding or manual worker, while in other cases we think that radial head resection can be the treatment of choice.  相似文献   
8.
9.
ObjectiveTo validate the Slovene version of the Orthotics and Prosthetics Users’ Survey (OPUS) 8-item Client Satisfaction with Device (CSD) questionnaire in upper-limb prosthesis users and to further verify measurement properties of this tool with Rasch analysis.DesignParticipants consisted of a convenience sample of 76 adults (54 men) using a prosthesis after unilateral upper-limb amputation who consecutively attended a follow-up visit at our centre.MethodsAfter translation and cross-cultural adaptation of the CSD into the Slovene language, we evaluated functioning of the rating scale categories, item fit (internal construct validity), reliability indices and dimensionality, as well as convergent and discriminant construct validity of the questionnaire.ResultsRasch analysis indicated that: (1) functioning of the 4 response options was acceptable; (2) all items fitted the measured construct [information-weighted (infit) and outlier-sensitive (outfit) mean-square statistics 0.60 to 1.40]; (3) person separation reliability was 0.62 (and Cronbach α = 0.76), item separation reliability was 0.83; (4) on principal component analysis (PCA) on the standardised residuals, the CSD showed borderline but acceptable unidimensionality and no local item dependency. Moreover, as expected, the CSD score showed good correlation with the QUEST 2.0 score (rs = 0.57) and little to fair correlation with the OPUS Upper Extremity Functional Status score (rs = 0.21).ConclusionThe metric properties of the Slovene version of CSD agree with previous studies. The present study confirms the validity of CSD for measuring patient satisfaction with an upper-limb device, enhances the confidence in this tool for assessing upper-limb prosthesis users, and contributes to further refining the technical quality of this measure.  相似文献   
10.
目的:设计出偏心改向髋臼内衬,以解决臼杯位置不良时内衬补救或翻修,及小髋臼关节置换问题。方法在Solidworks2012软件平台上,利用三维实体建模技术,设计一套偏心改向髋臼内衬,并进行模拟手术,预测手术效果。结果成功设计出一套偏心改向髋臼内衬,改向规格有0°、10°、20°、30°;偏心规格有球心偏向非负重侧2 mm的外径/内径的比值分别为42 mm/28 mm、40 mm/28 mm和38 mm/24 mm、36 mm/24 mm四种。模拟手术显示髋关节置换或翻修术后防脱位效果和活动范围。结论偏心改向髋臼内衬设计合理,用于臼杯位置不良时内衬补救或翻修及小髋臼大球头置换,模拟手术提示有防脱位功能。  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号