新鲜跟腱断裂的手术治疗

目的:探讨新鲜跟腱断裂的术中手术方法选择及术后康复,为临床治疗提供相应资料。方法:回顾研究2006年4月～2009年6月在我院骨科治疗的新鲜跟腱断裂31例,术中选择不同方法治疗,随访术后并发症及疗效。结果:所有患者均获得随访,术后1年优良93.55%。结论:不同的手术方法治疗新鲜跟腱断裂都有良好的临床疗效。     

丹参接骨胶囊对骨折SD大鼠TGFβ1 mRNA及蛋白表达的影响

目的:建立左股骨中段闭合折骨经皮髓内克氏针固定的标准骨折模型,观察丹参接骨胶囊对SD大鼠骨折愈合过程中局部转化生长因子β1(transforming growth factor beta 1,TGF-β1)mRNA、蛋白表达,通过RT-PCR,ELISA法进行分析转化生长因子β1的表达,探讨丹参接骨胶囊对大鼠骨折愈合的机制。方法:建立闭合性的股骨干骨折髓内固定模型,分别给与相应药物灌胃治疗,在不同时相通过RT-PCR,ELISA法进行分析TGF-β1 mRNA及蛋白表达。结果:丹参接骨胶囊能促进骨折SD大鼠TGF-β1 mRNA及蛋白的表达。结论:大鼠股骨中段闭合折骨髓内克氏针固定骨折模型稳定,可操作性强,重复性好。丹参接骨胶囊能促进骨折SD大鼠TGF-β1 mRNA及蛋白的表达。     

膝关节半月板半脱位的MRI测量与诊断

目的探讨膝关节半月板半脱位MRI测量方法与表现,提高对该病的认识和诊断准确性。方法回顾性分析200例膝关节症状患者的临床和影像资料,该批患者均行单膝关节MRI检查,采用统一的检查和测量方法,分析膝关节内、外侧半月板MRI表现(正常、退变、撕裂)与半月板半脱位发生率的关系。结果内侧半月板:MRI表现正常的31例,其中发生半脱位1例;MRI表现为退变的86例,发生半脱位14例;MRI表现为撕裂的52例,半脱位16例。内侧半月板不同MRI表现半脱位发生率的差别有统计学意义(χ2=7.261,P0.05)。外侧半月板:MRI表现正常的41例,其中半脱位1例;MRI表现为退变的95例,半脱位8例;MRI表现为撕裂的46例,半脱位9例。外侧半月板不同MRI表现半脱位发生率的差别有统计学意义(χ2=6.079,P0.05)。内、外侧半月板半脱位的发生率的差别有统计学意义(χ2=3.930,P0.05)。结论选择合理的测量方法,有利于膝关节半月板半脱位的诊断;膝关节内、外侧半月板撕裂后半月板半脱位的发生率增大。     

儿童肱骨髁上骨折内固定治疗分析

目的：探讨闭合复位加克氏针内固定治疗儿童肱骨髁上骨折的临床疗效,并与手术切开复位固定内固定效果进行比较。方法：2006年10月～2009年10月山东省即墨市中医院收治儿童肱骨髁上骨折患者80例,其中44例（观察组）采取闭合复位经皮克氏针内固定治疗,36例（对照组）采取手术切开复位内固定治疗,比较两组治疗效果及并发症。结果：随访时间为6个月～3年,平均1.5年,两组患者治疗后优良率比较,差异无统计学意义（χ2=4.56,P〉0.05）,但观察组患者住院时间、出血量、治疗费用等均低于对照组,两组比较,差异有统计学意义（χ2=9.27、17.34、21.41,P〈0.05）。结论：闭合复位经皮克氏针内固定治疗儿童肱骨髁上骨折,患者恢复快,创伤小,固定可靠,值得临床应用。     

32例骨梗死患者的MRI资料分析

骨梗死临床较少见，早期临床表现多不典型，X线平片检查常为阴性，易出现漏诊或误诊。笔者回顾性分析了我院2005年至2008年确诊为骨梗死的32例患者的MRI资料，现将结果报告如下。     

丹参接骨胶囊对闭合性股骨骨折模型大鼠骨折愈合的影响

BACKGROUND: Salvia miltiorrhiza bone-setting capsule is a traditional Chinese medicine for the treatment of fractures due to activating blood circulation to dissipate blood stasis, reducing swelling and pain. OBJECTIVE: To observe the effects of Salvia miltiorrhiza bone-setting capsule on the fracture healing in a rat model of closed femoral fractures. METHODS: Rats were randomly divided into salvia miltiorrhiza bone-setting capsule group, physiological saline group and normal group. In the salvia miltiorrhiza bone-setting capsule group and physiological saline group, rat models of closed femoral fractures were prepared, and then given physiological saline and salvia miltiorrhiza bone-setting capsule 2 pills by intragastric administration. In the normal group, rats were housed normally. At 7, 14 and 28 days after fractures, hematoxylin-eosin staining conditions, serum osteocalcin, the expression of collagen type I, and the expression of protein and mRNA callus transforming growth factor-beta 1 were observed in the salvia miltiorrhiza bone-setting capsule group and physiological saline group. RESULTS AND CONCLUSION: (1) Hematoxylin-eosin staining demonstrated that at 7 days after fractures, no significant difference was found in pathological changes of femoral fracture in salvia miltiorrhiza bone-setting capsule group and physiological saline group. At 14 and 28 days after fractures, pathological repair was more obvious in the salvia miltiorrhiza bone-setting capsule group than in the physiological saline group. (2) At 3 and 7 days after fractures, serum osteocalcin and the expression of type I collagen were significantly increased in the salvia miltiorrhiza bone-setting capsule group and physiological saline group  (P < 0.05), and the expression trend was consistent in both groups. The expression was always higher in the salvia miltiorrhiza bone-setting capsule group than in the physiological saline group, and significant differences were found at 14 and 28 days after fractures (P < 0.01). (3) Transforming growth factor beta 1 expression reached a peak at 3 days after fractures, gradually reduced, increased at 14 days (the second peak), and diminished at 28 days in the salvia miltiorrhiza bone-setting capsule group and physiological saline group. The expression trend of transforming growth factor beta 1 was consistent in the salvia miltiorrhiza bone-setting capsule group and physiological saline group. At 7, 14 and 28 days, the transforming growth factor beta 1 expression was higher in the salvia miltiorrhiza bone-setting capsule group than in the physiological saline group. (4) Results showed that salvia miltiorrhiza bone-setting capsule could promote fracture healing, and its mechanism was probably associated with serum osteocalcin, the expression of collagen type I and transforming growth factor-β1.       

单侧外固定架配合持续冲洗引流法治疗长管状骨骨髓炎

1998年10月~2003年11月,我院采用单侧外固定架配合持续冲洗引流治疗长管状骨骨髓炎50例,通过随诊观察,疗效满意。现报告如下。1临床资料1.1一般资料本组50例病人中,男32例,女18例;年龄17~63岁,平均41岁。50例病人均为陈旧骨折(胫骨骨折40例,并股骨干骨折7例,并肱骨干骨折3例)内     

活血化瘀临床应用研究

血瘀证与活血化瘀研究已成为中西医结合研究最活跃、最有成效的领域之一,并且广泛运用于内、外、妇、皮肤科等科,包括冠心病、高血压、糖尿病、肿瘤、硬皮病、肝硬化等多种疾病。就活血化瘀法在内科临床常见病中的应用做一概述。     

112例踝关节骨折手术治疗分析

目的总结踝关节骨折的手术方法和治疗效果。方法回顾分析112例踝关节骨折的手术治疗,应用改良的Baird和Jackson评分系统对疗效进行评定,并就骨折类型、骨折固定方法、术后功能锻炼的关系进行分析。结果随访时间为8～36个月,平均18个月。112例疗效为：优72例,良28例,可6例,差6例,优良率89．2％。结论手术治疗踝关节骨折可取得满意的骨折复位和临床疗效,复位的质量与疗效密切相关,判断骨折类型和选择固定方法对于提高复位质量,改善远期疗效十分重要。