蒲参胶囊治疗原发性高脂血症的多中心随机平行对照临床试验

目的进一步评价蒲参胶囊治疗原发性高脂血症的临床疗效.方法多中心随机平行对照临床试验.448例原发性高脂血症患者被随机分为两组:治疗组336例,服用蒲参胶囊;对照组112例,服用脂必妥片;两组疗程均为4周.主要疗效指标为总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)和高度脂蛋白(HDL-C).结果蒲参胶囊能使TC平均降低0.6246mmol/L,TG平均降低1.5343mmol/L,LDL-C平均降低0.5764mmol/L,HDL-C平均升高0.4406mmol/L;其中蒲参胶囊降低TG的疗效优于对照组(P＜0.005).结论蒲参胶囊对原发性高脂血症患者(尤其是TG升高者)有较好的调脂作用.     

高荣林从心论治失眠经验

高荣林教授认为,引起失眠的原因很多,五脏、六腑的功能失调均可导致失眠,其中心脏功能失调在失眠的发生中起着至为重要的作用。心主血脉,又主神明,为君主之官,是五脏六腑之大主,精神之所舍。心藏神,神在人体的生命活动中占有重要地位,作为人体重要生理功能的睡眠,也是由心所主     

路志正教授治疗发作性睡病撷菁

发作性睡病,其病因病机,不外虚实两端实邪干扰、正气不足,无论虚实,总以阳气不足,脾虚湿盛使然,与脾肾关系最为密切.路志正教授认为,病因病机,脾肾两脏是关键;辨证论治,祛湿醒神贯其中;知常达变,圆机活法开思路.指出多与内湿有关,治疗当注意祛湿,治疗中常用养心安神、重镇之类药物用于治疗发作性睡病.一则体现异病同治;二则体现中药具有双向调节作用,更合宜阴阳互根,治病求本之意.     

路志正脾胃论治心法

路志正教授家学渊源,精医术,勤临证,善研索,多年来形成了自己一套独特的行之有效的治疗方法,调理脾胃为其学术思想的重要组成部分。笔者有幸随师学习,深感其思路广阔,辨证详明,用药精当,现择其鳞爪以飨同道。1　调脾胃,治病必求本脾胃为后天之本,气血生化之源,气机升降之枢纽,二者维系人体升与降、纳与化、燥与湿的平衡。“人以胃气为本”,“有胃气者生,无胃气者死”,凡病之发生、转归、预后莫不与脾胃有关,所谓“内伤脾胃,百病由生”是也。故察病,必先察脾胃强弱;治病,必先顾脾胃盛衰,对于年老体弱,大病久病之人更应注意养护胃气,无论哪一…     

蒲参胶囊治疗高脂血症的临床疗效评价

目的观察蒲参胶囊对原发性高脂血症的调脂作用。方法240例原发性高脂血症患者随机分成两组,治疗组服用蒲参胶囊另加脂必妥片安慰剂;对照组服用脂必妥片另加蒲参胶囊安慰剂,两组疗程均为4周。观察其疗效及两组血脂(TC、TG、LDL-C和HDL-C)、血黏度变化等指标。结果治疗组总有效率(76．3％)优于对照组(48．7％,P<0．01);治疗后两组TC、TG、LDL-C明显降低,HDL-C明显升高(P<0．05或P<0．01);且TG治疗组明显优于对照组(P<0．01);治疗组全血高、低切黏度有一定降低(P<0．01)。结论蒲参胶囊对原发性高脂血症患者(尤其是TG升高者)有较好的调脂作用,且有一定的降低血黏度的作用。     

通心络胶囊治疗冠心病心绞痛量效时效的临床观察

OBJECTIVETo evaluate the dose and time effect of Tongxinluo capsule (TXLC) in treatment of angina pectoris (AP) caused by coronary heart disease. METHODS90 patients were randomized to receive 6,4, or 2 capsules of TXLC, when AP occurred. The contents were taken out from capsules and then took with water immediately. And the 30 patients in the control group were treated with 0.6 mg nitroglycerine given by sublingually. The dose and time effects were evaluated after 2 weeks treatment. RESULTSThe therapeutic effect in 6 and 4 capsules patients were more effective than patients in the conrtol. The percentage remission rate for AP in TXLC group was similar to that of the control group but the onset of action for TXLC was slower than that of nitroglycerine.CONCLUSIONAP caused by coronary heart disease can be relieved rapidly by 4 capsules of TXLC.     

陈鼎祺治疗心力衰竭经验

陈鼎祺老师是中国中医研究院广安门医院内科主任医师,全国第二届师承制教育导师。其多年来致力于中西医结合研究,尤其是在心脑血管和呼吸系统疾病等方面形成了一套行之有效的独特的治疗经验。笔者有幸随师学习,现将其治疗心衰的经验介绍如下。1 标本兼治,五脏并调有侧重充血性心力衰竭是各种心脏病所引起的严重心功能代偿不全的共同表现,根据其症状特点,当属中医之惊悸、怔忡、喘证、痰饮、水肿、症瘕、心痹等范畴。《素问     

Clinical Assessment on Treatment of Hyperlipidemia with Pushen Capsule (蒲参胶囊)

Objective: To explore the therapeutic effect of Pushen capsule (PSC, 蒲参胶囊) in treating primary hyperlipidemia. Methods: Two hundred and forty patients with primary hyperlipidemia were randomly divided into two groups, the 120 patients in the treated group treated with PSC (4 capsules, tid) and the 120 patients in the control group treated with Zhibituo tablet (脂必妥, 3 tablets, tid), and they were administered at the same time with Zhibituo placebo. The therapeutic course for both groups was 4 weeks. The therapeutic effect and the effects on blood lipids and viscosity were observed. Results: The effective rate in thetreated group was 76. 3%, which was significantly higher than that in the control group (48. 7% , P< 0. 01). PSC showed a significant lowering effect on TC, TG and LDL-C and raising effect on HDL-C, and the effect in lowering TG was significantly better than that of Zhibituo (P<0.01). PSC also showed a certain effect in decreasing whole blood viscosity of both high-sheared and low-shear     

路志正医案3则

1 产后痹证产后痹证是指产后百脉空虚,气血不足,复受风寒湿邪,气血运行不畅,致筋脉拘挛疼痛,不能屈伸的一种病证。路老认为,产后痹证不同于一般的痹证,有多虚多瘀的特点。其气血亏虚乃病之根本,只有正气强盛,人体才能在药物的协同下驱逐病邪。因此治疗上宜大补气血,濡润筋脉,通利关节,而不宜过用辛烈刚燥,更伤阴