全文获取类型
收费全文 | 25120篇 |
免费 | 1412篇 |
国内免费 | 131篇 |
专业分类
耳鼻咽喉 | 287篇 |
儿科学 | 512篇 |
妇产科学 | 525篇 |
基础医学 | 3229篇 |
口腔科学 | 1500篇 |
临床医学 | 1761篇 |
内科学 | 6445篇 |
皮肤病学 | 689篇 |
神经病学 | 1924篇 |
特种医学 | 463篇 |
外国民族医学 | 1篇 |
外科学 | 3748篇 |
综合类 | 134篇 |
一般理论 | 5篇 |
预防医学 | 2125篇 |
眼科学 | 537篇 |
药学 | 1491篇 |
中国医学 | 137篇 |
肿瘤学 | 1150篇 |
出版年
2023年 | 166篇 |
2022年 | 164篇 |
2021年 | 862篇 |
2020年 | 533篇 |
2019年 | 808篇 |
2018年 | 999篇 |
2017年 | 611篇 |
2016年 | 589篇 |
2015年 | 816篇 |
2014年 | 1118篇 |
2013年 | 1336篇 |
2012年 | 2034篇 |
2011年 | 2243篇 |
2010年 | 1176篇 |
2009年 | 1080篇 |
2008年 | 1661篇 |
2007年 | 1793篇 |
2006年 | 1621篇 |
2005年 | 1474篇 |
2004年 | 1284篇 |
2003年 | 1125篇 |
2002年 | 1070篇 |
2001年 | 169篇 |
2000年 | 173篇 |
1999年 | 146篇 |
1998年 | 155篇 |
1997年 | 131篇 |
1996年 | 98篇 |
1995年 | 89篇 |
1994年 | 74篇 |
1993年 | 85篇 |
1992年 | 80篇 |
1991年 | 79篇 |
1990年 | 79篇 |
1989年 | 52篇 |
1988年 | 43篇 |
1987年 | 40篇 |
1986年 | 45篇 |
1985年 | 61篇 |
1984年 | 53篇 |
1983年 | 31篇 |
1982年 | 44篇 |
1981年 | 47篇 |
1980年 | 26篇 |
1979年 | 28篇 |
1978年 | 19篇 |
1975年 | 20篇 |
1974年 | 27篇 |
1973年 | 21篇 |
1971年 | 19篇 |
排序方式: 共有10000条查询结果,搜索用时 140 毫秒
1.
Francisco José Álvarez García María José Cilleruelo Ortega Javier Álvarez Aldeán María Garcés-Sánchez Nuria García Sánchez Elisa Garrote Llanos Ángel Hernández Merino Antonio Iofrío de Arce Abián Montesdeoca Melián María Luisa Navarro Gómez Jesús Ruiz-Contreras 《Anales de pediatría (Barcelona, Spain : 2003)》2021,94(1):53.e1-53.e10
The CAV-AEP annually publishes the immunisation schedule considered optimal for all children and adolescent resident in Spain, taking into account the available evidence.The 2 + 1 schedule is recommended (2, 4, and 11 months) with hexavalent vaccines (DTPa-VPI-Hib-HB) and with 13-valent pneumococcal conjugate.A 6-year booster is recommended, preferably with DTPa (if available), with a dose of polio for those who received 2 + 1 schemes, as well as vaccination with Tdpa in adolescents and in each pregnancy, preferably between 27 and 32 weeks.Rotavirus vaccine should be systematic for all infants.Meningococcal B vaccine, with a 2 + 1 schedule, should be included in routine calendar.In addition to the inclusion of the conjugated tetravalent meningococcal vaccine (MenACWY) at 12 years of age with catch up to 18 years, inclusive, the CAV recommends this vaccine to be also included at 12 months of age, replacing MenC. Likewise, it is recommended in those over 6 weeks of age with risk factors or who travel to countries with a high incidence of these serogroups.Two-dose schedules for triple viral (12 months and 3-4 years) and varicella (15 months and 3-4 years) will be used. The second dose could be applied as a tetraviral vaccine.Universal systematic vaccination against HPV is recommended, regardless of gender, preferably at 12 years, and greater effort should be made to improve coverage. The 9 genotype extends coverage for both genders. 相似文献
2.
3.
Eduardo Rivadeneyra-Domínguez Jos Eduardo Prez-Prez Alma Vzquez-Luna Rafael Díaz-Sobac Juan Francisco Rodríguez-Landa 《Toxins》2020,12(11)
Cassava (Manihot esculenta Crantz) is a plant that contains neurotoxins such as linamarin and lotaustraline. Its long-term consumption is associated with neuronal damage and contributes to the development of motor impairment in humans and rats. We investigated the effects of the consumption of cassava juice on renal and hepatic function and motor impairments in male rats. The rats received the vehicle, non-toxic and toxic doses of cassava juice, or linamarin as a pharmacological control, over 35 consecutive days. The effects were evaluated in an open field test, rotarod, and swim test. The toxic cassava dose and linamarin resulted in motor impairments in the rotarod and swim test from day 7 of treatment. The toxic cassava dose and linamarin increased the parameters that indicate renal and hepatic damage, with the exception of total protein and albumin levels. Behavioral variables that show motor incoordination (i.e., latency to fall in the rotarod) were negatively correlated with biochemical parameters of renal and kidney damage, whereas spin behavior was positively correlated. Our data indicate that chronic oral consumption of cassava juice caused renal and hepatic damage that was correlated with motor coordination impairment in rats, similarly to their principal neurotoxic compound, linamarin. 相似文献
4.
5.
6.
7.
8.
Leopoldo Pérez de Isla Raquel Arroyo-Olivares Ovidio Muñiz-Grijalvo José Luis Diaz-Díaz Daniel Zambón Francisco Fuentes Juan F. Sánchez Muñoz-Torrero Juan Diego Mediavilla Aurora González-Estrada Jose Pablo Miramontes-González Raimundo de Andrés Marta Mauri Daniel Mosquera José M. Cepeda Lorena Suárez Miguel Ángel Barba-Romero Rosa Argüeso Pilar Álvarez-Baños Pedro Mata 《Journal of clinical lipidology》2019,13(6):989-996
9.
J. Oliveira-Santos R. Santos C. Moreira S. Abreu L. Lopes C. Agostinis-Sobrinho G. Stratton J. Mota 《Nutrition, metabolism, and cardiovascular diseases : NMCD》2019,29(8):783-792
Background and aimsThe long-term relations between excessive adiposity in early childhood and unfavourable cardiometabolic profiles in later ages are not yet completely understood. We aimed to assess the associations between birth weight (BW) and BMI from 6 months to 6 years of age, with biomarkers indicative of low-grade inflammation, insulin resistance and lipid profiles in adolescence.Methods and resultsRetrospective school-based study with 415 Portuguese adolescents (220 girls), mean age of 14.08 ± 1.6 years old. Anthropometric data from birth to 6 years old was extracted from individual child health book records. Actual weight and height were measured and BMI calculated. Participants were classified at each time point as normal weight or overweight according to WHO reference values. Biomarkers were obtained from venous blood samples. Linear regressions were used to explore the associations between the biomarkers and early life anthropometric indicators. From 2 years onwards, BMI associated positively with the inflammatory score and HOMA-IR in adolescence. Children who were overweight/obese from 2 to 6 years of age presented significantly higher inflammatory score and HOMA-IR later in adolescence. TC/HDL ratio was also positively associated with BMI from the age of 5 years onwards. The associations between BMI and cardiometabolic outcomes remained positive in adolescence, with overweight adolescents presenting a higher inflammatory score, HOMA-IR and TC/HDL than normal weight adolescents.ConclusionA high BMI from an early age was consistently associated with worse inflammatory and lipid profiles and insulin resistance in adolescence. No associations were found between BW and the same studied outcomes. 相似文献
10.