全文获取类型
收费全文 | 8154篇 |
免费 | 729篇 |
国内免费 | 437篇 |
专业分类
耳鼻咽喉 | 138篇 |
儿科学 | 195篇 |
妇产科学 | 133篇 |
基础医学 | 975篇 |
口腔科学 | 124篇 |
临床医学 | 1046篇 |
内科学 | 1211篇 |
皮肤病学 | 53篇 |
神经病学 | 363篇 |
特种医学 | 440篇 |
外国民族医学 | 1篇 |
外科学 | 796篇 |
综合类 | 1038篇 |
现状与发展 | 4篇 |
一般理论 | 2篇 |
预防医学 | 684篇 |
眼科学 | 201篇 |
药学 | 825篇 |
7篇 | |
中国医学 | 423篇 |
肿瘤学 | 661篇 |
出版年
2024年 | 9篇 |
2023年 | 92篇 |
2022年 | 174篇 |
2021年 | 308篇 |
2020年 | 302篇 |
2019年 | 274篇 |
2018年 | 297篇 |
2017年 | 272篇 |
2016年 | 302篇 |
2015年 | 384篇 |
2014年 | 467篇 |
2013年 | 481篇 |
2012年 | 674篇 |
2011年 | 733篇 |
2010年 | 426篇 |
2009年 | 338篇 |
2008年 | 401篇 |
2007年 | 479篇 |
2006年 | 389篇 |
2005年 | 397篇 |
2004年 | 274篇 |
2003年 | 255篇 |
2002年 | 226篇 |
2001年 | 154篇 |
2000年 | 134篇 |
1999年 | 169篇 |
1998年 | 103篇 |
1997年 | 92篇 |
1996年 | 68篇 |
1995年 | 84篇 |
1994年 | 63篇 |
1993年 | 51篇 |
1992年 | 44篇 |
1991年 | 56篇 |
1990年 | 52篇 |
1989年 | 54篇 |
1988年 | 39篇 |
1987年 | 32篇 |
1986年 | 28篇 |
1985年 | 30篇 |
1984年 | 8篇 |
1983年 | 10篇 |
1981年 | 10篇 |
1980年 | 6篇 |
1979年 | 6篇 |
1975年 | 8篇 |
1974年 | 14篇 |
1973年 | 6篇 |
1971年 | 6篇 |
1966年 | 5篇 |
排序方式: 共有9320条查询结果,搜索用时 125 毫秒
1.
A 2-year-old girl was diagnosed as Weill-Marchesani syndrome with typical systemic features of short stature, short and stubby hands and feet, language disorders and mental retardation. He developed bilateral angle closure glaucoma, ectopia lentis and suffered visual loss from the ocular features of Weill-Marchesani syndrome. The child was successfully treated by combined CO2 laser-assisted sclerectomy surgery and trabeculectomy. 相似文献
2.
“三全育人”视角下思政教育机制实践与探索——“杏林成长导师”计划的构建 《医学教育管理》2021,7(6):656-660
“三全育人”是高校思政教育工作的关键一环,也是中医药高校推动思政教育的重要内容。以“三全育人”为视角对北京中医药大学思想政治教育举措“杏林成长导师”计划路径、内容深入分析,运用统计分析和文献研究方法,剖析该计划对中医学专业大学生的学业、思想和实践等多个层面的现实成效,从而为“三全育人”理念在中医药院校制度建构中的应用提供新的视角与方法。 相似文献
3.
No national epidemiological investigations have been conducted recently regarding facial lacerations. The study was performed using the data of 3,634,229 people during the 5-year period from 2014 to 2018 archived by the National Health Information Database (NHID) of the Health Insurance Review and Assessment Service. Preschool and children under 10 years old accounted for about one-third of patients. Facial lacerations were concentrated in the “T-shaped” area, which comprised forehead, nose, lips, and the perioral area. The male to female ratio for all study subjects was 2.16:1. Age and gender are significantly related with each other (P < .001). Mean hospital stays decreased, and numbers of outpatient department visits per patient were highest for hospitals and lowest for health agencies. Over the study period, hospital costs per patient in tertiary and general hospitals increased gradually. Preschool and school-aged children are vulnerable to trauma. Male patients outnumbered female patients by a factor of more than 2. The “T-shaped’” area around forehead is vulnerable to injury. Total cost of medical care benefits per patient in tertiary hospitals was about 7 times on average than in health agencies. Regarding functional, behavioral, and aesthetic outcomes, more attention should be paid to epidemiologic data and hospital costs for facial lacerations. 相似文献
4.
目的总结一体化腹腔镜摄像系统在单孔腹腔镜腹股沟疝全腹膜外修补术(SILS-TEP)的应用经验。
方法回顾性分析中山大学附属第五医院胃肠外科2017年9月至2018年4月30例采用一体化腹腔镜摄像系统进行SILS-TEP患者的临床资料。
结果所有手术均顺利进行,无一例中转开放或多孔,平均手术时间(58.6±4.3)min,平均出血量(6.5±2.4)ml,术后1 h VAS评分(3.36±0.66)分,术后8 h为(2.15±0.75)分,术后1 d出院。术后血清肿3例,其中1例多次抽液后痊愈,2例1个月后完全自行吸收。术后随访6个月,无复发、腹股沟区慢性疼痛、切口感染等情况发生。
结论使用一体化腹腔镜摄像系统进行SILS-TEP安全、可行、有效,可以减少器械在体外的对抗干扰,有利于该手术的开展。 相似文献
5.
6.
7.
Sergey Motov Stefan Mann Jefferson Drapkin Mahlaqa Butt Antonios Likourezos Elizabeth Yetter Jason Brady Nechama Rothberger Ankit Gohel Peter Flom Mo Mai Christian Fromm John Marshall 《The American journal of emergency medicine》2019,37(2):220-227
Study objective
We compare the analgesic efficacy and safety of subdissociative intravenous-dose ketamine (SDK) versus morphine in geriatric Emergency Department (ED) patients.Methods
This was a prospective, randomized, double-blind trial evaluating ED patients aged 65 and older experiencing moderate to severe acute abdominal, flank, musculoskeletal, or malignant pain. Patients were randomized to receive SDK at 0.3?mg/kg or morphine at 0.1?mg/kg by short intravenous infusion over 15?min. Evaluations occurred at 15, 30, 60, 90, and 120?min. Primary outcome was reduction in pain at 30?min. Secondary outcomes included overall rates of adverse effects and incidence of rescue analgesia.Results
Thirty patients per group were enrolled in the study. The primary change in mean pain scores was not significantly different in the ketamine and morphine groups: 9.0 versus 8.4 at baseline (mean difference 0.6; 95% CI ?0.30 to 1.43) and 4.2 versus 4.4 at 30?min (mean difference ?0.2; 95% CI ?1.93 to1.46). Patients in the SDK group reported higher rates of psychoperceptual adverse effects at 15, 30, and 60?min post drug administration. Two patients in the ketamine group and one in the morphine group experienced brief desaturation episodes. There were no statistically significant differences with respect to changes in vital signs and need for rescue medication.Conclusion
SDK administered at 0.3?mg/kg over 15?min provides analgesic efficacy comparable to morphine for short-term treatment of acute pain in the geriatric ED patients but results in higher rates of psychoperceptual adverse effects.ClinicalTrials.gov Registration #: NCT02673372. 相似文献8.
9.
10.
目的 探讨类风湿关节炎患者外周血miR-150-5p、细胞因子信号抑制因子1(suppressor of cytokine signaling 1,SOCS1)mRNA的表达及对类风湿关节炎(Rheumatoid Arthritis,RA)疾病诊断、中医证型判断的意义。方法 纳入符合诊断标准的RA患者57例及健康对照组19例,根据《22个专业95个病种中医诊疗方案》有关RA的中医证候诊断标准,判断RA的中医证型。qPCR检测RA患者及健康对照组miR-150-5p、SOCS1mRNA的相对表达水平,同时检测血常规、肝功能、肾功能等常规指标。双荧光素酶分析方法判断两者是否存在靶向关系。统计分析miR-150-5p、SOCS1 mRNA对RA疾病的诊断意义及其与中医证型的相关性。结果 RA患者外周血miR-150-5p的相对表达水平下调,低于正常人群(t = -19.019,P < 0.05);其表达水平随疾病活动度升高,有下降趋势;患者外周血SOCS1 mRNA的相对表达水平上调,低于正常人群(t = 5.333,P < 0.05);其表达水平随疾病活动度升高,有上升趋势。MiR-150-5p与SOCS1 mRNA有靶向结合关系(P < 0.05)。通过AUC曲线比较,miR-150-5p的相对表达水平区分RA的敏感性及特异性分别为98.1%、92.1%(AUC = 0.972,P < 0.05);SOCS1 mRNA的相对表达水平无法区分RA(AUC = 0.472,P > 0.05)。RA患者中miR-150-5p的相对表达水平低于3.06,RA患者风湿痹阻证、寒湿痹阻证的相对风险分别为8.33、250.00(P < 0.05)。结论 miR-150-5p、SOCS1 mRNA在RA患者中有差异性表达,且有靶向结合关系。miR-150-5p可能是RA的疾病诊断及中医风湿痹阻证、寒湿痹阻证证型诊断的潜在生物标志物。 相似文献